Quality Of Life In Psychological Domain Research Articles

Changes in the quality of life in patients with multiple sclerosis treated with ocrelizumab

To study the quality of life (QoL) in patients with multiple sclerosis (MS) treated with ocrelizumab for at least 12 months. Thirty-eight patients were observed, including 13 with primary progressive MS (PPMS), 15 with highly active relapsing-remitting MS (HAMS) and 10 with secondary progressive MS (SPMS) with relapses. QoL was studied using unspecific SF-36 and MS-specific MusiQoL questionnaires. Depression and fatigue were assessed with the Beck Depression Scale (BDS) and the Modified Fatigue Impact Scale (MFIS). Basic characteristics of QoL indexes of the patients were similar to those previously reported for these MS variants. After 6 and 12 months, a significant increase in the indexes of the majority of SF-36 and MusiQoL scales was identified that shows a significant improvement in both physical and psychological domains of QoL. The significant and rapid decrease in depression severity after 6-month treatment with ocrelizumab may at least in part be associated with improvement of indexes of vitality, general health, social relations and the total QoL score.

The effect of wheelchair Tai Chi on balance control and quality of life among survivors of spinal cord injuries: A randomized controlled trial

BackgroundWheelchair-related falls are common in survivors with spinal cord injury (SCI). We aimed to assess the effects of wheelchair Tai Chi (WCTC) practice on balance control and quality of life (QOL) among SCI survivors. Materials and methodsForty SCI survivors were equally divided into WCTC and control groups. The control participants only received the normal rehabilitation intervention, while the WCTC intervention involved 30-min sessions, 2 sessions/day, and 5 days/week for 6 weeks. Static sitting balance, trunk muscle strength, handgrip strength, and QOL were evaluated and statistically analyzed. ResultsCompared with the control group, static sitting balance, left handgrip strength, and the psychological domain of QOL improved significantly in the WCTC group (time by group interaction, p < 0.05). ConclusionSix weeks' WCTC training improved static sitting balance and QOL in survivors with SCI. It may be a feasible, safe, and effective exercise for SCI survivors.

Burnout and Quality of Life Among Massage Therapists with Visual Impairment

Purpose The aim of this study was to evaluate the level of burnout syndrome and quality of life (QoL) among Polish massage therapists, and determine their relationship with sociodemographic and work-related variables. Methods A group of 43 participants aged 28–63, who were blind or poor-sighted were recruited for the study. They were surveyed with sociodemographic data questionnaire and the Polish versions of the Maslach Burnout Inventory-General Survey and WHOQOL-BREF. Results The overall level of exhaustion was 6.79 ± 4.45, cynicism was estimated at 7.30 ± 3.43, and professional efficacy was 23.3 ± 5.44. Regarding QoL, the psychological domain was the highest (73.6 ± 10.0), while the physical domain was the lowest (61.1 ± 6.94). None of the sociodemographic variables or occupational factors had any statistical relationship with any burnout subscale. Significant correlations were found between the psychological domain of QoL and marital status (H = 6.570; p = 0.037), years of practice (ρ = 0.315; t = 2.124; p = 0.039), hours of practice per week (ρ = 0.364; t = 2.505; p = 0.016) and private practice (z = 2.393; p = 0.017). Significant relationships were found between the environmental domain of QoL and the place of residence (H = 5.977; p = 0.050) and between hours of practice per week (ρ = 0.335; t = 2.276; p = 0.028). A significant positive correlation was noted between professional efficacy and the social relationship domain (ρ = 0.306; t = 2.056; p = 0.046). Conclusion Job activity plays a crucial function in the psychosocial rehabilitation of massage therapists with visual impairment. This was confirmed by the low risk of burnout, and the psychological domain being the highest of QoL.

Physical activity moderates the deleterious relationship between cardiovascular disease, or its risk factors, and quality of life: Findings from two population-based cohort studies in Southern Brazil and South Australia

BackgroundFew studies have investigated the relationship between physical activity (PA) of low intensity and duration with quality of life (QoL) among individuals at risk or with cardiovascular disease (CVD).ObjectivesTo investigate whether PA of different intensity and duration moderates the relationship between CVD and its risk factors (obesity, hypertension, diabetes, dyslipidaemia) and QoL in adults.MethodsPopulation-based cross-sectional studies using data from the EpiFloripa Cohort Study (Southern Brazil; n = 1,220, 38.8±12.0 years, 48.2% males) and the North West Adelaide Health Study (NWAHS, South Australia; n = 1,661, 43.7±11.1 years, 49.7% males). The physical and psychological domains of QoL were assessed using the WHOQOL-Bref (EpiFloripa) or the SF-36 (NWAHS) questionnaires. The diagnosis of CVD and its risk factors were self-reported. PA was self-reported and quantified by its intensity [“walking” or moderate/vigorous (MVPA)] and duration (none, 1–150, ≥150 min/week). Both studies were analysed separately, and results were adjusted for sociodemographic variables.ResultsParticipants at risk or with CVD from both studies showed a lower QoL than ‘healthy’ individuals with a stronger relationship for the physical domain. PA duration showed a direct-trend relationship with QoL, but the associations were stronger for MVPA in both studies. However, when stratified by health status, the magnitude of the association between “walking” duration and a higher physical QoL was greater among those at risk or with CVD compared to ‘healthy’ individuals. Conversely, among Australians with CVD, MVPA was associated with a better physical QoL only when its duration was ≥150 min/week. All associations were stronger in the NWAHS than in the Brazilian study.Conclusions“Walking” was more prevalent than MVPA and was consistently associated with a better physical QoL among those at risk or with CVD. These findings should be considered in the design of public health interventions designed to increase PA and improve QoL.

Use of modern contraceptive methods and its association with QOL among Nepalese female migrants living in Japan.

IntroductionModern contraceptive use among migrants may be limited due to factors such as language barriers, socio-economic condition, and inadequate knowledge. Limited evidence is available on the factors associated with the use of modern contraceptive methods by migrants in Japan. Moreover, evidence remains scarce on the quality of life (QOL) of migrants in relation to contraceptive use. As the Nepalese migrant population in Japan is increasing, this study was conducted to address their sexual and reproductive health issues. Therefore, the objectives of this study were to examine the factors associated with the use of modern contraceptive methods and to explore the association between the use of modern contraceptive methods and QOL among married Nepalese female migrants in Japan.MethodsThis is a cross-sectional study conducted among 189 married Nepalese female migrants residing in five prefectures of Japan from August to October 2016. This study employed snowball sampling to recruit the migrants. Simple and multiple logistic analyses were used to examine the association between independent variables and the use of modern contraceptive methods. Similarly, multiple linear regression analysis was used to examine the association between the use of modern contraceptive methods and quality of life.ResultsMigrants who had higher knowledge of modern contraceptive methods were more likely to use them (Adjusted Odds Ratio [AOR] = 1.31; 95% Confidence Interval [CI]: 1.07, 1.60). The psychological domain scores were higher in those who used modern contraceptive methods (Coefficient [B] = 0.58; 95% CI: 0.05, 1.11).ConclusionThis study highlights the importance of the knowledge of modern contraceptive methods to increase their use. Also, the use of modern contraceptive methods improves the psychological QOL domain scores of the migrants using them. These results suggest a need for sexual and reproductive health education for migrants, especially pertaining to modern contraceptive use.

Association of physical activity with cardiovascular and renal outcomes and quality of life in chronic kidney disease.

Patients with chronic kidney disease (CKD) are more readily prone to have impaired physical activity than the general population. The aim of this study is to examine the relationship between physical activity and adverse clinical outcomes and quality of life (QOL) in CKD. One hundred and sixty-one patients with CKD stages 1–5 was enrolled from February 2013 to September 2013 and followed up until June 2016. Physical activity was measured using high handgrip strength, 30-second chair stand, and 2-minute step. The QOL was assessed using the Taiwan version of the World Health Organization Quality of Life-BREF. Clinical outcomes included commencing dialysis, major adverse cardiovascular events (MACEs), and first hospitalization. Of all participants, 1 kgf increase in handgrip strength was significantly associated with 0.13 score increase in total scores of QOL and 0.05 score increase in physical domain of QOL in adjusted analysis. One time increase in 30-second chair stand was significantly correlated with 0.14 score increase in psychological domain of QOL. Over a mean follow-up period of 29.1±11.2 months, 37 (23.0%) reached commencing dialysis, 11(6.8%) had MACEs, and 50(31.1%) had first hospitalization. High handgrip strength (hazard ratio (HR): 0.89, 95% CI: 0.84–0.96) and high 2-minute step (HR: 0.04, 95% CI: 0.01–0.95) were significantly associated with decreased risk for commencing dialysis in multivariate analysis. Thirty-second chair-stand was negatively associated with MACEs (HR: 0.65, 95%CI: 0.47–0.89) and first hospitalization (HR: 0.84, 95%CI: 0.74–0.95). In conclusion, physical activity is a potential predictor of QOL and adverse clinical outcomes in patients with CKD.

The Effects of Age and Gender on the Quality of Life of People with Chronic Back Pain in Bosnia and Herzegovina

Purpose: Quality of life (QOL) is an important area of research in many scientific disciplines, and the findings could help in designing strategies to improve QOL for various clinical conditions. Chronic low back pain is a frequent medical condition that has a detrimental effect on QOL. The goal of this study was to examine the QOL of people with chronic low back pain in Bosnia and Herzegovina (BIH), and to assess the impact of demographic variables such as age and gender on the QOL. Methods: The study sample consisted of 50 people with low back pain, between 19-79 years of age (mean age 51.2, SD- 13.1 years). There were 35 females (70%) and 15 males (30%) in the sample. The instrument used for measuring the QOL was World Health Organisation Quality of Life scale BREF (WHOQOL BREF). Results: The study demonstrated that low back pain has a detrimental effect on QOL. There was a significant effect of age and gender on certain domains of QOL. Conclusions: Older age is a risk factor for lower QOL of people with chronic low back pain. Females are more likely to have lower scores on the psychological domain of QOL,and therefore need effective psychological interventions aimed at improving their QOL.

Quality of life improvement in Latinas receiving combined substance use disorders and trauma-specific treatment: a cohort evaluation report

BackgroundThis study evaluates the benefits of integrating behavioral health and trauma services for Latinas with a history drug use. Changes in quality of life (QOL) domains were documented after participation in a manualized intervention in a cohort of Latinas.MethodsParticipants were part of a prospective cohort study of 136 Latinas with co-occurring disorders (COD) who may have experienced trauma and receiving services in our outpatient treatment facility in Bayamón, Puerto Rico. The WHOQOL-BREF Spanish version was used to score physical, psychological, social, and environmental QOL domains, at intake and after six months. Sociodemographic variables, alcohol, drug use, mental health disorders, and severity of substance use disorders (as defined by the DSM-5) were also tabulated. Descriptive statistics and paired t test or the Wilcoxon signed-rank test were computed for comparison.ResultsA median age of 39 years was seen and with 76% high school education or higher degree. The majority were unemployed (95.9%). A diagnosis of severe cocaine use (51.4%) was present and almost half (49.5%) had three or more DSM-5 diagnoses. Mean QOL scores were higher at six months with statistically significant differences in each domain. Women with neurodevelopmental disorders and schizophrenia yielded higher mean QOL scores for each domain at six months except for the social domain. Women with polydrug use and women who reported exposure to trauma and depressive disorder experienced statistically significant increments in the physical, psychological and social domains in comparison to counterpart women.ConclusionsSignificant and positive changes in QOL were found in each domain. Latinas who reported traumatic events had lower scores in the physical and psychological QOL domains. There was a high prevalence of diminished physical and mental functioning in Latinas with COD. The exposure to trauma and the lack of social support negatively affect treatment access and retention for Latinas.

Effects of 6 months yoga program on renal functions and quality of life in patients suffering from chronic kidney disease.

Aim:To study the effect of 6 months yoga program in patients suffering from chronic kidney disease (CKD).Materials and Methods:Fifty-four patients with CKD were studied and divided into two groups (yoga group and control group) to see the effect of yoga in CKD. Patients in the yoga group were offered yoga therapy along with other conventional treatment modalities, while the control group was only on conventional treatment. Subjects in yoga group were trained to perform specific yogic asanas for at least 5 days a week for 40–60 min a day. Regular monitoring of blood pressure, renal function, requirement of a number of dialysis, and quality of life (QOL) indicators were done. Fifty patients (yoga – 25; control-25) completed 6 months follow-up.Results:In yoga group, a significant reduction of systolic and diastolic blood pressure, significant reduction in blood urea and serum creatinine levels, and significant improvement in physical and psychological domain of the World Health Organization QOL (as assessed by BREF QOL scores) were seen after 6 months. In control group, rise of blood pressure, deterioration of renal function, and QOL were observed. Poststudy comparison between the two groups showed a statistically significant reduction of blood pressure, nonsignificant reduction in blood urea and serum creatinine, and significant improvement in physical and psychological domain of QOL in yoga group as compared to control group. For subjects in yoga group, the need for dialysis was less when compared to control group although this difference was statistically insignificant. Except for inability of some patients to perform certain yogic asanas no adverse effect was found in the study.Conclusion:Six months yoga program is safe and effective as an adjuvant therapy in improving renal functions and QOL of CKD patients.

Is history of suicidal behavior related to social support and quality of life in outpatients with bipolar I disorder?

Bipolar disorder (BD) affects the social functioning and quality of life (QoL) of its patients. This study aimed to investigate whether there is an association between social support (SS), and suicidal behavior in BD I patients compared to healthy controls; secondarily, we evaluated the influence of QoL on those variables. A total of 119 euthymic outpatients with BD I, 46 of whom had attempted suicide (SAs) and 73 who had not (non-SAs), were compared to 63 healthy controls, through the Medical Outcomes Study Social Support Scale and World Health Organization's Quality of Life Instrument. No differences were noted in SS and QoL between SAs and non-SAs. Compared to healthy controls, non-SAs showed lower values in the positive social interaction domain of SS, and the patients, as a whole, showed lower values in affectionate and positive social interaction domains of SS. Compared to healthy controls, SAs had lower values in the environmental domain of QoL, and the patients, as a whole, had lower values in the environmental, social, and psychological domains of QoL. There was positive correlation between SS and QoL. Although BD is a disabling disease, patients receive inadequate SS. Interventions that may alter the SS in these patients should be investigated.

Change in Quality of Life and Its Association with Oral Health and Other Factors in Community-Dwelling Elderly Adults-A Prospective Cohort Study.

To determine whether changes in oral health status were associated with decline in quality of life (QoL). Prospective cohort study. Carlos Barbosa, southern Brazil. A random sample of 872 community-dwelling individuals aged 60 and older was evaluated in 2004. The current study population consisted of 389 participants available for follow-up in 2012. Change in QoL was assessed through the use of the short version of the World Health Organization QoL Assessment tool (WHOQOL-BREF) at baseline and follow-up. Each WHOQOL domain generates a score, with changes being calculated for each domain. Individuals with the same or higher scores at follow-up were categorized as having improved QoL, and those with lower scores were categorized as having a decline in QoL. Sociodemographic and health variables were assessed in an interview, and tooth loss, use of dental prostheses, and satisfaction with chewing ability and oral appearance were verified through oral examinations. Interviews and examinations were repeated. Risk ratios (RRs) relative to the outcome and independent variables were estimated using Poisson regression with a robust variance estimator. Tooth loss was a risk factor for decline in the psychological domain of QoL (RR = 1.04, 95% confidence interval (CI) = 1.02-1.06). Improvement in satisfaction with chewing ability was a protective factor for decline in this same domain (RR = 0.69, 95% CI = 0.50-0.97). Greater satisfaction with oral appearance was a protective factor against decline in social (RR = 0.84, 95% CI = 0.72-0.98) and environmental (RR = 0.77, 95% CI = 0.61-0.97) domain scores. Preventing tooth loss and recognizing and properly addressing concerns about chewing and dental appearance can affect the general well-being of community-dwelling elderly adults.

An Exploratory Study to Determine the Quality of Life (QoL) and Factors Leading to Imprisonment among Women Prisoners in a Selected Women Prison

The research study titled “An exploratory study to determine the quality of life (QoL) and factors leading to imprisonment among women prisoners in a selected women prison” was based on the objectives; to determine the quality of life of women prisoners, to explore the factors leading to imprisonment, to find the association between the QoL of women prisoners and selected socio demographic and clinical variables, to find the association between the QoL and domains of quality of life of women prisoners and to find the association between the QoL of women prisoners and factors leading to imprisonment. Survey approach with an exploratory design was adopted and was conducted in a selected women prison. The conceptual framework was based on the Quality of Life model at the Centre for Health Promotion, University of Toronto. The study had primary outcome variables as quality of life and factors leading to imprisonment among women prisoners. Seventy samples were selected by purposive sampling technique. The tools used for the study were validated, pretested and the reliability also was established. The major findings of the study revealed that 43 (61.4%) participants have good quality of life. Among seventy participants 21 (30%) of them had poor QoL in psychological domain. Thirty seven (52.9%) of the participants had good QoL score in physical domain and 36 (51.4%) of them had medium QoL score in psychological domain. Majority 51 (72.9%) of the samples had good QoL score in social domain and 46 (65.7%) of them had good QoL score in environmental domain. Majority i.e. 61 (87.1%) of them had good QoL score in spiritual domain. Among the 70 participants, 10 (14.3%) of the participants had poverty as the leading reason for committing crime, followed by 8 (11.4%) having physical abuse and another 8 (11.4%) having family breakdown as the factor leading to imprisonment. Among the socio demographic variables; age of women prisoners has statistically significant association with the QoL of women prisoners (p<0.05). Among the clinical variables; Blood pressure and Lipid profile (Total serum cholesterol) have statistically significant association with quality of life (p=0.048). Physical, psychological and social domains have statistically significant association with the QoL of women prisoners (p<0.05). Factors leading to imprisonment has statistically significant association with the QoL of women prisoners (p <0.05).

P18.10 Determinants of quality of life among people living with human immunodeficiency virus (plhiv) in coastal south india

Aim To assess the quality of life (QOL) of PLHIV and to identify the factors influencing their QOL. Method A cross-sectional study was conducted among 302 PLHIV aged 18 years and above, attending ART centre of Kasturba Medical College Hospital, Mangaluru, India from April to December 2014. Institutional Ethics Committee (IEC) approval was obtained prior to the commencement of the study. After obtaining a written informed consent, PLHIV were interviewed using WHOQOL-HIV BREF questionnaire to assess their QOL. Data was entered in, and analysed using SPSS version 16. Results The mean scores (SD) across the six domains of QOL were physical- 16.37 (2.18); psychological- 12.40 (2.02); level of independence- 13.56 (2.28); social relationship- 12.19 (1.69); environment- 12.37 (2.03) and spirituality- 12.42 (2.23). A statistically significant difference was observed between the various domain scores of QOL (psychological; level of independence; social relationship; environment and spirituality) with socio economic status (SES) of PLHIV (P 0.05). A significant difference was also observed between psychological domain of QOL among PLHIV and the presence of opportunistic infection. (P = 0.028) Conclusion In our study, poor SES and presence of opportunistic infection have an adverse effect on QOL among PLHIV receiving ART.

Measures of Nutritional Status and Quality of Life in Adult People Living with HIV/AIDS at a Tertiary Hospital in Nigeria

Background & Aims: The study investigated the relationship between objective and subjective nutritional status parameters and quality of life in HIV seropositive patients. Methods: Retrospective review of clinic records of 150 HIV seropositive patients at a teaching hospital in Nigeria. Nutritional status was evaluated objectively with anthropometry including body mass index (BMI), subjectively with malnutrition universal screening tool (MUST) and subjective global assessment (SGA) tool. Data on quality of life (QOL) assessed with WHOQOL (Bref), and CD4 count were extracted. Correlation analysis and linear regression were done to investigate the relationship between variables, level of significance set at p < 0.05 respectively. The CD4 count correlated with percentage body fat (r = 0.224), MUST (r = -0.186) and SGA (r = -0.192), p < 0.05 respectively, but not with any of the QOL domains. Weight, MUST, SGA, percentage body fat were significant predictors of the percentage weight change in 6 months. Conclusions: BMI has significant positive association with psychological domain of QOL. MUST and SGA have significant negative association with certain domains. QOL did not predict short-term weight changes, as did the current weight, MUST, and SGA.

Exercise and severe major depression: Effect on symptom severity and quality of life at discharge in an inpatient cohort

BackgroundExercise is a potential treatment for depression. However, few studies have evaluated the role of adjunct exercise in the treatment of severely major depressed inpatients. The goal of this study was to evaluate the effects of add-on exercise on the usual treatment of severely depressed inpatients. MethodsFifty participants were randomized to an exercise (exercise + usual treatment) or a control (usual treatment) group. Twenty-five patients were randomly allocated to each group. The participants in the exercise group performed three sessions per week throughout the hospitalization period, with a goal dose of 16.5 kcal/kg/week plus the usual pharmacological treatment. Depressive symptoms and the Quality of Life (QoL) of the participants were assessed at the baseline, the second week, and discharge. ResultsA significant group × time interaction was found for depressive symptoms and the physical and psychological domains of QoL. Differences between groups occurred at the second week and discharge with respect to depressive symptoms and the physical and psychological domains of QoL. There was no difference in the remission rate at discharge (48% and 32% for the exercise and control group, respectively). An NNT of 6.25 was found. No significant baseline characteristics predict remission at discharge. ConclusionAdd-on exercise is an efficacious treatment for severely depressed inpatients, improving their depressive symptoms and QoL. Initial acceptance of exercise remains a challenge.

Quality of life among people living with hypertension in a rural Vietnam community.

BackgroundTo respond to growing prevalence of hypertension in Vietnam, it is critical to have an in-depth understanding about quality of life (QOL) among people living with hypertension and related factors. This study aimed to measure QOL among hypertensive people in a rural community in Vietnam, and its association with socio-demographic characteristics and factors related to treatment.MethodsThis study was conducted in a rural community located 60 km from Ho Chi Minh City. Face-to-face interviews were conducted among 275 hypertensive people aged 50 years and above using WHOQOL-BREF questionnaire. Descriptive statistics were used to examine mean scores of quality of life. Cronbach’s alpha coefficient and Pearson’s correlation coefficient were applied to estimate the internal consistency, and the level of agreement between different domains of WHOQOL-BREF, respectively. Independent T-test and ANOVA test followed by multiple linear regression analyses were used to measure the association between QOL domains and independent variables.ResultsBoth overall WHOQOL-BREF and each domain had a good internal consistency, ranging from 0.65 to 0.88. The QOL among hypertensive patients was found moderate in all domains, except for psychological domain that was fairly low (mean = 49.4). Backward multiple linear regressions revealed that being men, married, attainment of higher education, having physical activities at moderate level, and adherence to treatment were positively associated with QOL. However, older age and presence of co-morbidity were negatively associated with QOL.ConclusionWHOQOL-BREF is a reliable instrument to measure QOL among hypertensive patients. The results revealed low QOL in psychological domain and inequality in QOL across socio-demographic characteristics. Given the results, encouraging physical activities and strengthening treatment adherence should be considered to improve QOL of hypertensive people, especially for psychological aspect. Actions to improve QOL among hypertensive patients targeted towards women, lower educated and unmarried patients are needed in the setting.

Water-Based Exercise and Quality of Life in Women: The Role of Depressive Symptoms

Several studieshave evaluated the relation of exercise to quality of life (QoL). To our knowledge, no study has evaluated the relation of water-based exercise to depressive symptoms and QoL, or the association between improvement in QoL and depressive symptoms in healthy women. The purpose of this study was to evaluate the association of water-based exercise with changes in QoL. Forty-seven women performed water-based combined exercise for 12 weeks. All participants improved in the physical and psychological domains of QoL. Decreases in depressive symptoms and improvements in maximal strength and aerobic capacity were found for all participants. A regression model revealed that depressive symptoms were associated with improvements in physical and psychological domains of QoL. The results showed that moderate intensity, water-based exercise improved physical and psychological domains of QoL, depressive symptoms, aerobic capacity, and muscular strength of women. Furthermore, the improvement in physical and psychological domains of QoL appeared to be mediated by the antidepressant effects of exercise, but not by changes in aerobic capacity or muscular strength.

Quality of Life in Patients With Psychotic Disorders

The aims of this study were to assess the relative contribution of symptoms and specific psychosocial factors to different domains of quality of life (QoL) in patients with psychotic disorders. Positive, negative, and depressive symptoms; Five-Factor Model personality traits; and attachment dimensions were assessed in 110 patients with nonaffective psychotic disorders. Hierarchical and stepwise regression analyses were conducted. Psychosocial factors were able to predict all domains of QoL, when symptom severity was controlled for. Furthermore, the physical QoL domain was best predicted by attachment, personality, and sex (R = 43.1%); the psychological QoL domain, by personality and depressive symptoms (R = 60.5%); the social domain, by personality and positive symptoms (R = 30.3%); and the environmental domain, by personality and negative symptoms (R = 27.9%). Our findings highlight the role that specific individual characteristics play in different aspects of QoL in patients with psychotic disorders.

Epstein‐Barr virus antibody titer and its association with the domain scores from the World Health Organization's Quality of Life questionnaire: Findings from Rural Hainan Province, China

Epstein-Barr virus (EBV) antibody titer has recently been used as a biomarker of psychological stress. This is the first study to investigate the association between EBV antibody titer and perceived quality of life (QOL) in Hainan Island, China. Participants from two regions of Hainan Island, recruited into a larger study investigating the health impact of rapid economic development among rural residents, were stratified by age, sex, and region; 15 people were randomly selected from each of the 16 subgroups, to give a total sample size of 240. EBV antibody titer in dried blood spot samples was measured by enzyme-linked immunosorbent assay. The abbreviated version of the World Health Organization's Quality of Life questionnaire was used to gather information on six categories of QOL. Multiple linear regression analysis was used to examine the relationship between EBV antibody titer and QOL. After adjusting for the effects of age, sex, region and C-reactive protein concentration, EBV antibody titer was negatively associated with the physical (P = 0.044) and psychological QOL domains (P = 0.039). This study suggests that among individuals living in an environment in the initial stages of economic development EBV antibody titer, a biomarker of psychological stress, is not only associated with the psychological aspects of QOL but is also linked to physical problems.

Quality of sleep and quality of life in higher education students

Introduction Numerous studies exist about the associations between sleep and quality of life (QoL), in samples with diagnosis of sleep disorders (e.g., insomnia, sleep apnea) or other medical conditions (e.g., cancer). However, very few studies have examined community samples. The purpose of the present work was to analyze the associations between subjective sleep quality and several dimensions of QoL in higher education students. A secondary specific aim was to examine whether or not sleep quality would be a significant predictor of QoL after statistically controlling for psychopathological symptoms. Materials and methods A sample of 324 undergraduate and master degree students completed the Portuguese versions of the Pittsburgh Sleep Quality Index (PSQI), WHOQOL-Bref to measure QoL, and Brief Symptom Inventory (BSI) to measure psychopathological symptoms. Results All PSQI components were significantly associated (at least p .05) with the QoL General Facet, and with the Psychological and Physical QoL domains. As to the Environment QoL domain and the PSQI components, four statistically significant associations emerged; as to the Social Relationships QoL domain and the PSQI components, only two significant associations emerged. The strongest associations found were between the PSQI Component 1-Subjective Sleep Quality, and the Psychological QoL domain (r = −.546, p .0001), followed by the Physical QoL domain (r = −.446, p .0001). Two PSQI components, C1-Subjective Sleep Quality and C7-Daytime Dysfunction, were systematically associated with all WHOQOL-Bref domains and general facet. Hierarchical regression analyses showed that the PSQI components added significant contributions to the general QoL facet, and to the Psychological and Physical QoL domains, after controlling for psychopathological symptoms. Conclusion Our results suggest that in non-clinical samples composed of predominantly healthy and young adults, there are numerous significant associations between several components of sleep quality and different facets of quality of life, and that these associations emerge regardless of psychopathological symptoms. Acknowledgements To the Dep. of Education – Univ. Aveiro, for the support with the printed materials. To the Psychology Master Degree Coordinator, who authorized this study. To Ana R. Salgueiro, Carolina T. Carlos, Joana M. Ribeiro and Raphaelle G. Dischler, for their help in data collection.