Neurofibromatosis type 1 (NF1) is a genetically determined disease characterized by damage to all organs and systems with dominant involvement of the skin and peripheral nervous system. One of the main NF1 features is the age-dependent representation of its clinical symptoms, which is the reason for untimely diagnosis verification and inadequate medical care which in its turn entails the risks for severe disability and reduced life expectancy. Obviously, the key factors in improving the prognosis for life and its quality are the improvement of screening, diagnostics, therapy and rehabilitation programs, both in childhood and in adult patients. The issues of social and psychological adaptation of patients and their families are highly relevant, this therefore requires the availability of information sources and the involvement of a multidisciplinary team of medical specialists at all stages of medical care. The purpose for publication of this bibliographical review was to highlight the features of diagnosis and observation of children with NF1 as well as existing treatment options for associated diseases.
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