Macadamia (Macadamia integrifolia, M. integrifolia × M. tetraphylla) trees were pruned at different times at sites near Alstonville, northern New South Wales, Australia, to examine the effects on vegetative flushing, subsequent flower raceme production and yield. Pruning of cv. 849 and cv. A268 modified the cycle of flush development. Pruning times that resulted in immature flushes on the canopy in late autumn or early winter inhibited raceme production. In contrast, pruning in late May and early June did not generally reduce raceme production relative to production on unpruned trees. The times of pruning that reduced raceme production also reduced yield. The yields of trees pruned in late May were also reduced, presumably because of decreased light interception. In the season after treatment the trees pruned in early April had greater numbers of racemes per unit of tree canopy volume than the trees pruned in late May. The trees of the lighter flowering cv. 849 pruned in early April had higher yield efficiencies than the trees pruned in late May, whereas there was no effect on yield efficiency in the prolifically flowering cv. A268. The differences in raceme production in the season after pruning may have been due to a combination of an alternate bearing response, characteristics of the stems produced after pruning, or maturity of the flushes. In a separate experiment, uniconazole sprays immediately after pruning reduced the length of the new stems, slowed canopy expansion, and increased kernel recovery compared with untreated hedged trees, but did not affect flowering or yield. In another experiment, hedging in early June had no effect on raceme production in cv. 849 trees in consecutive seasons, and no effect on canopy volume or yield in the first season. In contrast, canopy volume and yield were reduced in the second season. Finally, pruning of young, yet-to-flower cv. 849 trees from late winter to spring staggered flush development, with the earliest pruned trees producing more racemes and setting more fruit than the later pruned trees.