Prospects For Use Research Articles

РЕТРОДОСВІД БЛАГОДІЙНОЇ ТА МЕЦЕНАТСЬКОЇ ПІДТРИМКИ СТАНОВЛЕННЯ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ УКРАЇНИ

The actualization of research on the problem of charitable and philanthropic support for the formation of higher education institutions of Ukraine is due to the fact that constructive retro-experience has prospects for use for the post-war recovery and development of modern institutions of higher education in Ukraine. The purpose of the study is to analyze the experience of charitable and philanthropic support for the establishment of higher education institutions in Ukraine at the beginning of the 19th century. Research methods. Achieving the goal of the article made it possible to use the methods of analysis, synthesis, comparison, concretization and generalization. The article specifies the main approaches to interpreting the concepts of «charity», «charitable activity», «patronage», «patronage activity». Based on the analysis of dissertations and scientific publications, it was established that the establishment of higher education institutions in Ukraine at the beginning of the 19th century took place with significant charitable and philanthropic support from broad sections of the population: nobles, craftsmen, former Cossacks, and peasants. It manifested itself in the provision of funds for the opening of higher education institutions, the transfer of material assets and land allotments, etc., which significantly supplemented budget funding. The value of the experience of charitable and philanthropic support for the formation and development of the system of higher education in Ukraine in the first half of the 19th century is indicated, since philanthropists were the initiators and sponsors of the opening of most universities, higher women's courses, lyceums and schools (gymnasiums) of higher sciences, and philanthropic support for the opening and development of universities and institutions of higher professional education in Ukraine in the 19th century became a common phenomenon.

FTase inhibitors and cancer: prospects for use in targeted therapies

FTase inhibitors and cancer: prospects for use in targeted therapies

Stable vortex waves generation by a flexible antenna made of highly conductive graphene film

Electromagnetic waves carrying orbital angular momentum (OAM and vortex waves) attract much attention due to their specific characteristics and prospects for use in wireless communication, biomedical engineering, and imaging. Vortex waves are complex spatial entities; therefore, their stable generation is a quite complicated task, especially in the radio frequency and terahertz wave domains, considering that the corresponding antennas must be precisely adjusted. Such adjusting is very difficult to achieve for flexible antennas, which are now being actively introduced into practice. Here, we propose a design of a flexible antenna that is able to stably generate waves carrying OAM even when being subjected to some bending. The antenna is composed of a ring-shaped resonator made of a highly conductive graphene film deposited on a thin polydimethylsiloxane substrate. The antenna is operated on two mutually orthogonal degenerate TMm1 modes excited by two supply strip lines to generate vortex waves with a desired topological charge. We verify this ability numerically and in a microwave experiment on two antenna prototypes deriving the OAM mode purity by changing the bending radius of the antenna bearing surface, giving it either positive or negative curvature. The obtained experimental results confirm that the antenna has good performance and can be used for flexible electronic devices and communication systems.

METHODS FOR CLOSING PERFORATIONS OF GASTRIC AND DUODENAL ULCERS

This literature-based review analyzes different methods of closure of perforated gastric and duodenal ulcers. In addition, there have been determined the indications for the use of each method, the technique of performing, the advantages and disadvantages, as well as the prospects for use and their feasibility at the current level of abdominal surgery development.

Stress softening of nanoparticle-crosslinked hydrogels described using a physics-based damage model

Despite the promising applications of hydrogels, their poor mechanical properties still greatly limit their further applications. To improve the mechanical properties of hydrogels, various strategies have been proposed. Hydrogels with nanoparticle-crosslinked polymer networks show excellent toughness, self-recovery, and other advantages, and thus have great prospects for use in tissue engineering, artificial muscles, flexible electronics, and other fields. There have been experimental and theoretical studies of its damage. However, the underlying microscale physical mechanisms have not been fully elucidated. Herein, we established a physics-based constitutive model to describe the mechanical behavior of nanoparticle-crosslinked hydrogels under cyclic loading. The deformation-induced damage and the rate-dependent damage were explained by the network alteration and kinetics of chain dissociation/association, respectively. The kinetics dissociation/association theory was modified considering the polymer chains that wind around nanoparticles. The Mullins stress softening and recovery during cyclic loading were described. Cyclic loading tests on nanoparticle-crosslinked hydrogels were carried out to verify the proposed constitutive model. It is demonstrated that the model can well describe the mechanical behavior of nanoparticle-crosslinked hydrogels during cyclic loading.

Gearing towards the sustainable energy transformation, production, and storage using thermic modulated [Ce3+-Pr3+-Nd3+]:CsPbI2.7Br0.3 perovskite hetero-system

Current investigation elucidates the first report on the designing, optimization, and applications of the lanthanide tri-doped CsPbI2.7Br0.3 establishing [Ce3+-Pr3+-Nd3+]:CsPbI2.7Br0.3 (CPN:CPVSK). This novel heterostructure remained optically active for 28 days with the narrowed band gap ranging between 1.65 and 1.7 eV. CPN:CPVSK was identified with the cubic phase and average crystallite size was 58.92 nm. The spin coated thin films were marked by excellent compactness and maximal covering. As photo-converter inside an entirely air-processed perovskite solar cell, CPN:CPVSK attained the efficiency of 17.92 % and 1.1 V of the open circuit voltage (Voc). CPN-CPVSK decked nickel foam electrode expressed moderate affinity towards production of oxygen while the pure hydrogen generation activity was remarkable with the overpotential and kinetic Tafel slope value of 143.1 mV and 119.7 mV dec−1, respectively. With an impressive electrochemical service life, this electrode was also characterized with the commendable charge storage with the unit capacity of 567 mAH g−1 and a negligible equivalent series resistance (Rs) i.e. 0.51 Ω. CPN:CPVSK is a sustainable and energy efficient choice which has prospects for use in the energy systems at practical scale for maximizing the efficiency and stability.

Development of intelligent tools for logistics: practice and prospects of use

The article examines SMART products (SMARTtechnologies, SMART- systems, SMART-objects) used by logisticians in the process of carrying out logistics activities for business structures and others. It is noted that today, without SMART-products, logistics will lose its position as an effective tool that helps market players effectively conduct business and work effectively in the conditions of the development of globalization and internationalization of the market space. The purpose of the article is a thorough review and analysis of modern SMART-products, which are advisable to use in the field of logistics in order to rationally organize the logistics activities of enterprises, based on the formation of competitive supply chains. It was established that digitalization is currently one of the key factors of increasing value not only for individual enterprises and industries, but also for states. It is argued that the digital transformation marked the beginning of a new stage in the development of logistics - digital logistics based on the development of SMART-products: SMART-technologies, SMART-systems, SMART-objects. The main intelligent products are characterized, namely: Internet of Things, robotics and cyber systems, artificial intelligence, big data, paperless technologies, additive technologies (3D printing), cloud and fog computing, unmanned and mobile technologies, biometric technologies, quantum technologies, identification technologies, blockchain. It is noted that the listed products are constantly supplemented, in accordance with the development of IT technologies and means of communication between digital devices. It is substantiated that SMART -products are an important factor in the growth of sales volumes and obtaining significant profits from logistics activities. A thorough analysis of the suitability for use by logisticians in the practical activities of software products, which became the basis for the digitalization of transport, blockchain, big data (BIG DATA), uberization, was carried out; SMART technologies – 3D printing, sensor technologies (ST), GRID - technologies; SMART-objects - augmented reality (ar - augmented reality), smart products, drones, unmanned transport, robotics, as well as SMART-systems - cyber-physical systems (CPS) used in production (CYBER-PHYSICAL PRODUCTION SYSTEM (CPPS), intelligent systems and the Internet of Things (INTERNET OF THINGS). It has been proven that SMART -products today are able to ensure a high level of competitiveness of business entities in various sectors of the economy: wholesale and retail trade, agriculture, industry, health care, postal services, etc. Key words: logistics, intelligent logistics tools, logistics activity, digital transformation, logistics efficiency, logistics effectiveness, competitiveness.

PLATANUS L. GENUS IN TRANSCARPATHIA

Brief overview is provided below concerning the distribution of various sycamore species within the region of Transcarpathia, along with the coexistence of other Platanus L. species and interspecific hybrids within this geographic area. The purpose of the article is to study the species composition and distribution of species of the Platanus genus in Transcarpathia and the historical aspect of introduction, prospects for use in the landscaping of cities and villages of the Transcarpathian region. Methodology. In the course of the study, the following methods were used: 1) a comparative-descriptive method of determining tree species; 2) a comparative genetic research method for the oldest tree of this genus in Transcarpathia – the «Drugeth sycamore». The research topic involving the introduction of plane trees as exotic species holds undeniable significance. This importance stems from the intensive urbanization, the consistent rise in anthropogenic pressure on the biosphere, and the increasing levels of air pollution. These factors collectively contribute to the growing complexity of the ecological landscape, thereby emphasizing the pressing need for environmental conservation and protection. Scientific novelty. Historically, plane trees were introduced in almost all cities of the Transcarpathian region. Until now, these trees are actively used to plant greenery in parks, squares and roadsides. A detailed dendrological study of certain species of exotics complements the floristic analysis of landscaping in the cities of Transcarpathia, which is currently carried out by scientists and special expert groups. Conclusions. It’s clear that the study of the genus Platanus in the Transcarpathian region is essential for understanding the species composition and distribution of these trees in the area. It's especially important to clarify the classification of sycamores to distinguish between different species and hybrids accurately. The identification of the «Drugeth sycamore» as Platanus acerifolia (Aiton) Willd. is a valuable contribution to understanding the local flora. The conservation status of the «Drugeth sycamore» highlights its significance and the need for protective measures. Installing a fence around the tree and providing an informational and protective board are excellent suggestions to preserve and protect this ancient giant from potential harm. These measures would not only ensure its longevity but also educate the public about the importance of conserving such unique and historically significant trees. Further research and documentation of the genus Platanus in Transcarpathia will help in better managing and preserving these trees and enriching the local biodiversity. It’s encouraging to see efforts aimed at understanding and protecting the natural heritage of the region.

Antimicrobial activity of saponin-containing plants: review

The resistance of pathogenic microorganisms to antibiotics has become a "scourge" of the medical field in recent decades. In this regard, the vector of medical research rightly changed in favor of the search for natural mechanisms to fight pathogens. Nature has produced mechanisms for maintaining balance for millions of years, so it is reasonable to investigate and, in the future, use such mechanisms. This current study reviews and analyzes the last five years of research on the effects of saponin-containing plants on the most common pathogens. The analysis of literary data confirms the growing interest in natural antimicrobial drugs that are currently used in folk medicine or have the prospect of use in humane medicine in different countries of the world. Wide interest of the scientific community in the search for alternative antimicrobial agents, which would make it possible to overcome antibiotic resistance in the treatment of various types of diseases, has been revealed. Current scientific research has confirmed or disproved the effectiveness of only a thousandth part of all possible plants. Undoubtedly, the use of natural plant components will make it possible to make the treatment process cheaper and more effective, so this direction of research is currently very promising from all points of view.

Bacillus subtilis RBT-7/32 and Bacillus licheniformis RBT-11/17 as New Promising Strains for Use in Probiotic Feed Additives.

The normal functioning of a gastrointestinal microflora in poultry and livestock is of significant importance, since its imbalance negatively influences an organism's functions. In this study, the UV mutagenesis and selection were used to obtain two Bacillus strains possessing antagonistic activity towards Escherichia coli and Staphylococcus aureus, and their potential as a probiotic feed additive was evaluated. Compared to the parental strains, the ability of B. subtilis RBT-7/32 and B. licheniformis RBT-11/17 strains to suppress E. coli increased by 77 and 63%, respectively; the corresponding ability of these strains to suppress S. aureus increased by 80 and 79%, respectively. RBT-11/17 could not utilize microcrystalline cellulose and carboxymethyl cellulose, whereas cellulolytic activity of RBT-7/32 was doubled compared to the initial strain. The amylolytic activity of new strains was increased by 40%. Cultivation of strains on media containing soybean, pea, and corn meal did not provide any difference in the biomass production compared to the control. The heating of a water suspension of a dried biomass of the strains for 10-20 min at 80 and 100 °C or incubation in water solutions of citric, ascorbic, acetic, and formic acids (pH 3.0) for 3 and 24 h at 40 °C did not provide any negative influence on the spore survivability. Both strains were evaluated for their resistance to a number of veterinary antibiotics. Thus, RBT-7/32 and RBT-11/17 strains have good prospects for use in feed additives.

Molecular genetic abnormalities in ACTH-secreting pituitary tumors (corticotropinomas): fundamental research and prospects for use in clinical practice

In recent years, a large number of studies have been carried out to research molecular genetic abnormalities in ACTH--secreting pituitary tumors. This review presents a comprehensive analysis of exome studies results (germline and somatic mutations, chromosomal abnormalities in corticotropinomas which developed as part of hereditary syndromesMEN 1, 2, 4, DICER1, Carney complex etc., and isolated tumors, respectively) and transcriptome (specific genes expression profiles in hormonally active and inactive corticotropinomas, regulation of cell cycles and signal pathways). Modern technologies (next-generation sequencing - NGS) allow us to study the state of the microRNAome, DNA methylome andinactive chromatin sites, in particular using RNA sequencing. Thus, a wide range of fundamental studies is shown, theresults of which allow us to identify and comprehend the key previously known and new pathogenesis mechanisms andbiomarkers of corticotropinomas. The characteristics of the most promising molecular genetic factors that can be used in clinical practice for screening and earlier diagnosis of hereditary syndromes and isolated corticotropinomas, differential diagnosis of various forms of endogenous hypercorticism, sensitivity to existing and potential therapies andpersonalized outcome determination of Cushing`s disease.

Методика застосування інноваційних технологій навчання в диригентсько-хоровій підготовці майбутніх учителів музичного мистецтва

The purpose of the article is to consider the extent to which innovative tech­nologies are in demand in higher education institutions in the context of studying conducting and choral disciplines and to determine their feasibil­ity, effectiveness, usefulness and prospects for use in the training of future choirmasters. The authors determine the necessity and expediency of form­ing an innovative space for a number of disciplines based on the use of achievements of communication technologies. They reveal the effective­ness and efficiency, usefulness and prospects of their use in the process of training choral conductors. The introduction of innovative technologies in educational practice is con­ditioned by the fact that it should serve as a means of solving some urgent problems of a certain University and pass experimental testing for its final implementation. One of the types of innovative technologies in such classes is the use of vir­tual electronic music choral anthology, which is systematized in the form of a table with URL to the music medium, sheet music and text files that are freely available online. Another innovation in the study of the cycle of conducting and choral disciplines is the creation of an intellectual map. This method is appropriate when studying the theory of conducting (its technical component, artistic and expressive, communicative and psychological, man­agerial and organizational). Along with intelligence maps, there are also so-called web quests, which are aimed at expanding the knowledge of concepts and terms related to understanding the specifics of conducting activities. Distance learning encourages teachers of almost all specialties, including conducting and choral specialties, to introduce such a form of work as a webinar. Often in the process of studying conducting and choral disciplines, students undergo so-called socio-psychological training. Practice shows that today the use of some of the latest technologies in the context of studying conducting and choral disciplines in higher education not only stimulates the activity of students in the educational process, but also gives it an innovative appeal. At the same time, they contribute to the creation of a creative atmosphere in the seminar-type classes, provide an opportunity for self-realization of creative potential when students perform independent work, thereby improving the quality of learning material.

Девиации как гипотетическая основа негласно-конспиративного сегмента оперативно-розыскной деятельности (на примере легендированных объектов)

The article is devoted to the analysis of the modern crime detection means and methods. The author considers that contemporary operative-investigation activity is based on diverse functional and legal tools; some of them are similar to the oldest socio-psychological deviations of society, but aimed at achieving the social and humanistic goals of society. 
 The Russian legislation declares the right of the subjects of the operative-investigation activity to «create enterprises, institutions, organisations and divisions necessary to solve tasks», but does not reveal the essence of these terms, called in the professional environment «legendary objects».
 On the basis of a comparative and meaningful analysis of some excerpts from the classic work «The Golden Calf» with the provisions of modern Russian operative-investigation legislation, scientific views on the issues of the operative-investigative activity and the recent detective practice, the author highlights the main features of such a means of «legendary object” and talks about its genesis, purpose, current condition and prospects for use in solving the problems of crime prevention and detection.
 The author concludes on possible directions for using legendary / undercover objects in revealing a wide range potential criminals and documenting their criminal activities, as well as in detecting and solving crimes.

Piperacillin-tazobactam: prospects for use in real-world practice

A review of the literature concerning the efficacy and safety of combined anti-pseudomonas protected ureidopenicillin piperacillin/tazobactam usage. Randomized clinical trials and their meta-analysis have demonstrated that piperacillin/ tazobactam among non-carbapenem β-lactams is an equally effective alternative to carbapenems in the treatment of severe infections, including those caused by extended-spectrum β-lactamase producing strains, regardless of the infection locus. It can be used in cases of carbapenem de-escalation if it is necessary. The use of this antimicrobial therapy strategy is justified not only from a clinical, but also from an economic point of view.

A Universal Strategy for Modular Tunable Full‐Color Circularly Polarized Luminescent Materials with Afterglow

AbstractCircularly polarized luminescence (CPL) has shown significant potential for use in optoelectronic information and biomedical applications. Previously, the construction of CPL in thin films has often required the introduction of chiral groups into the system, which is efficient but complicated to synthesize and separate enantiomeric isomers. This manuscript proposes a simple and efficient strategy to construct dye‐doped polyvinyl alcohol (PVA) thin films with controlled orientation of the panchromatic CPL signal. This strategy can be generalized to the construction of thin‐film CPL. Besides, the metal‐free pure circularly polarized afterglow material is reported here to be adjustable. Moreover, the PVA films can be cut and stacked in a modular way to obtain different emission effects to induce mixed CPL, and three primary colors can be piled up together to induce white CPL. The PVA film has good prospects for use in optical devices, for example, anti‐counterfeiting of information and optical information encryption.

Advances in Solution‐Processed OLEDs and their Prospects for Use in Displays (Adv. Mater. 43/2023)

Advances in Solution‐Processed OLEDs and their Prospects for Use in Displays (Adv. Mater. 43/2023)

Cryptocurrencies as a new form of money: prospects for use and impact on the financial system in the future

In today's environment modern economic technologies are rapidly developing. This process and its impact on the financial system as a whole requires all the details effective consideration. Given that cryptocurrencies are highly dynamic in the market, the article proposes prospects for further use of the new currency. Accordingly, the purpose of the research was to provide a comprehensive analysis of cryptocurrencies as digital currencies in the Ukrainian economic market, trends, and prospects for their introduction. In the article such methods as special scientific methods (methods of collecting information, methods of processing information, methods of conducting analytical work) and general scientific methods (analysis, synthesis and generalization) were used. It allowed carrying out a complex study based on the principles of systematicity, scientificity and specificity. Search engines revealed more than 70 works on the issue of cryptocurrencies. In the course of the study, 40 in-depth studies from 2019 to 2023 were selected. The results provided a strategy for the impact and transformation of cryptocurrencies on the reform of the economic sector in general. It has been established that the introduction of cryptocurrency into the Ukrainian economy will facilitate the digitalisation of the economy. Based on the analysis of market denominations, crypto-exchanges and cryptocurrencies in the world are aimed at people, management, savings, and services. The research analysed the concept of the content of “cryptocurrency”, its features, advantages and disadvantages, and the relationship with the economic world. The international cryptocurrency market, the general state, development factors, and dynamics of adaptation in Ukraine were studied. The main conclusions were reflected in a comprehensive study of cryptocurrencies and their rapid growth as major technological innovations in the global and Ukrainian economy.

ПОВЫШЕНИЕ ЭКСПЛУАТАЦИОННЫХ ХАРАКТЕРИСТИК ГИПСОВОГО КОМПОЗИТА ДЛЯ ДЕКОРАТИВНЫХ ИЗДЕЛИЙ

The article discusses the results of research on the use of modifying additives in gypsum binder. Regulation of the structure and, therefore, the properties of gypsum stone can be carried out using small quantities of highly active additives that can effectively influence the formation of the structure of gypsum stone, and, consequently, its characteristics. Using functional modifying additives in small quantities, which practically do not affect the cost of the material, and using them to control the composition of gypsum binders, it is possible to obtain effective decorative and finishing gypsum products with improved characteristics.
 The work studied the effect of polyvinyl acetate additives together with synthetic polypropylene fiber on the properties of gypsum stone products. A comparison of the physical and mechanical characteristics of modified gypsum composites is presented, and the advantages of introducing fiber are revealed. By covering the pores and capillaries of gypsum stone with fiber fibers, the formation of shrinkage microcracks is significantly reduced, crack resistance increases, and strength characteristics increase.
 It has been established that modification of gypsum stone with polyvinyl acetate together with synthetic fibers helps to improve the physical and mechanical characteristics of gypsum stone. The developed compositions of decorative and finishing gypsum tiles using the additions of polyvinyl acetate and polypropylene fiber make it possible to obtain gypsum finishing materials products with improved characteristics, which demonstrates their increased efficiency as a modern finishing material and opens up broad prospects for use in housing and civil construction.

Assessment of the variation in nutritional composition and safety of dried recovered food from United States households and prospects for use in chicken feed

IntroductionNew poultry feed valorization pathways for recovered household food could be enabled by commercially available household devices that dry uneaten food material, arrest spoilage, and preserve nutrient content. However, the nutrient composition, safety, and feed incorporation potential of dried recovered household food (DRHF) is presently unknown.MethodsThirty-eight households spanning 31 states participated in a 4-to-6-week survey to generate and collect food residues that were dried using an in-home device. The DRHF samples were evaluated for chemical composition, digestibility of energy and amino acids, and safety to determine their potential for inclusion in chicken feed.Results and discussionThe DRHF had average levels of 15.9% crude protein, 13.3% crude fat, and 22.6% neutral detergent fiber, and 3.18 kcal/g of nitrogen-adjusted true metabolizable energy (by dry weight). The Windows User-Friendly Feed Formulation 2.1 modeler was used to perform linear programming and develop chicken feed rations for broilers and layers that incorporated DRHF alongside conventional feed ingredients, including corn, soybean meal, dicalcium phosphate, limestone, synthetic amino acids, salt, vitamin premix, and mineral premix. The feed formulation results showed that, on average, DRHF incorporation rates of up to 33 and 37% (by weight) are predicted to avoid any nutrient deficiencies or electrolyte imbalances in the broiler and layer rations, respectively. In the broiler ration, DRHF displaced corn, soybean meal, and limestone to varying degrees, while corn, soybean meal, animal fat, dicalcium phosphate, and limestone were substantially displaced in the layer rations. Addition of vitamin premix was predicted as necessary to facilitate DRHF inclusion in the layer rations. Furthermore, foodborne pathogens, mycotoxins, and heavy metals were either absent or below United States regulatory threshold levels. Measured levels of biogenic amines and fat/oil oxidation were consistent with prior research showing compatibility with chickens. These results can inform future in vivo feeding trials to validate the use of DRHF with varying properties in poultry feed.

Polyhydroxyalkanoates: Biosynthesis Optimization and Design of Antimicrobial Composites

Background. The accumulation of plastic waste negatively affects the environment and human health. Currently, one of the strategies to address this global ecological problem involves the utilization of biodegradable plastics instead in place of synthetic ones. Among them, polyhydroxyalkanoates (PHA) – microbial intracellular polymers – hold a significant position. Their advantages are biodegradability, biocompatibility, and favorable thermomechanical properties. Given these attributes, PHA has significant prospects for use in medicine, agriculture, and the food industry, in particular for packaging food products. Objective. Enchance the efficiency of bacterial synthesis of polyhydroxyalkanoates through nutrient media modification, obtain antimicrobial composites based on PHA, and determine their antimicrobial properties. Methods. The optimization of PHA biosynthesis involved selecting appropriate cultivation conditions, including carbon and nitrogen sources, cultivation time, and working volume. The isolation of PHA from bacterial biomass was achieved through chloroform extraction (mixing for 10 h at 35 °C, with a biomass-to-chloroform ratio of 1:50); followed by precipitation with double the volume of isopropanol. The resulting polymer was then dried to a constant weight at 60 °C. The hydrophobicity of the biopolymer was assessed using the water contact angle measurement. Composites of biopolymers with antimicrobials in the form of films were obtained using two methods: 1) solution casting method; and 2) layering the biocides onto the polymer film. The antimicrobial activity of the resulting composites was determined using the agar diffusion method. Results. Through the optimization of the mineral media and the change of cultivation conditions, it was possible to obtain 0.26–1.45 g/l of polyhydroxyalkanoates (5.1–34.0% PHA from biomass). The R. ruber UCM Ac-288 strain synthesized the maximum amount of biopolymer (34.0% PHA). This study established the ability of Gordonia bacteria to synthesize PHA for the first time. PHA compositions of optimal content were obtained, with hydrophobicity comparable to that of polyethylene packaging films. Antimicrobial pro­perties of biopolymers composites with biocides have been substantiated. Conclusions. The bacterial synthesis of PHA was increased by modifying nutrient media. Composites based on PHA with biocides were developed. It was determined that these composites exhibit antimicrobial properties and high hydrophobicity. Consequently, they hold promise for use as biofilms for packaging and preser­ving food products.