Propylene Glycol Solution Research Articles

Vapor-phase oxidation of propylene glycol-methanol mixture to methyl lactate on CeO2/Al2O3 catalyst

The vapor-phase oxidation of mixtures of propylene glycol with methanol and ethanol to methyl and ethyl lactate, respectively, on supported CeO2/Al2O3 catalyst at 210-2500С was investigated. Air oxygen and a flow reactor with a fixed catalyst bed were used. A 20% solution of propylene glycol in alcohol was supplied to the reactor inlet. Oxidation of propylene glycol in the presence of methanol occurs according to the overall reaction CH3CHOHCH2OH +O2 + СН3OH = CH3CHOHCOOСН3 +2H2O. First, hydroxyacetone is formed, which is further oxidized to pyruvic aldehyde, which adds alcohol to form a hemiacetal. Next, this hemiacetal is rearranged according to Cannizzaro into methyl lactate. At 2200C and catalyst load < 2 mmol PG/gcat/h, the selectivity for methyl lactate reached 70 wt.% at 100% propylene glycol conversion. In the presence of ethanol, the formation of a significant amount of acetaldehyde and its aldol condensation products, as well as the formation of diethoxyethane, was observed. Therefore, the selectivity for ethyl lactate at 100% propylene glycol conversion did not exceed 45%.

Machine-learning based thermal conductivity prediction of propylene glycol solutions: Real time heat propagation approach

The objective of this paper is to evaluate the capability of an ANN to classify the thermal conductivity of water-glycol mixture in various concentrations. Massive training/validation/test temperature data were created by using a COMSOL model for geometry including a micropipette thermal sensor in an infinite media (i.e., water-glycol mixture) where a 500 ?s laser pulse is irradiated at the tip. The randomly generated temporal profile of the temperature dataset was then fed into a trained ANN to classify the thermal conductivity of the mixtures, whose value would be used to distinguish the glycol concentration at a sensitivity of 0.2% concentration with an accuracy of 96.5%. Training of the ANN yielded an overall classification accuracy of 99.99% after 108 epochs.

Ichthyosis vulgaris: An updated review.

Ichthyosis vulgaris is an inherited, non-syndromic form of ichthyosis that presents with skin problems. Making up more than 95% cases of ichthyosis, ichthyosis vulgaris is caused by heterozygous loss-of-function mutation of the filaggrin gene, raising the fragility and permeability of the stratum corneum. It typically presents in infancy as xerosis, skin lesions, keratosis pilaris, palmoplantar hyper linearity, scaly dermatosis, and erythroderma, clearly identifiable by age 5. Although majority of patients have a normal lifespan, possible complications include a vitamin D deficiency and auditory problems due to scaling in the ears, besides a drop in quality of life due to dermatological changes. Urea-based creams with 10% urea, ceramides, and other ceramides are often the first line therapy in ichthyosis vulgaris. There is no known curative treatment for ichthyosis vulgaris, but lifelong treatment can alleviate the symptoms. Urea-based creams are highly therapeutic, whereas ammonium lactate 12% lotion with a physiological lipid-based repair cream can help with scaling and dryness. There is also evidence in favour of propylene glycol solutions. Risankizumab, an anti-interleukin-23 drug, and enhancement of natural moisturizing factors are also two highly promising solutions that require additional research. This review aims to provide updates on the manifestation, evaluation, and treatment of ichthyosis vulgaris.

Determination of fluorescence quantum yields and decay times of NADH and FAD in water–alcohol mixtures: The analysis of radiative and nonradiative relaxation pathways

Combined studies on fluorescence quantum yield of coenzymes NADH and FAD in water–methanol, water–ethanol and water–propylene glycol mixtures and on time-resolved fluorescence of these molecules under excitation at 450 and 355 nm by means of time-correlated single photon counting (TCSPC) method have been carried out. A novel model that allowed to separate the contributions from several excited state relaxation mechanisms to fluorescence dynamics in the pico- and nanosecond time domains and to fluorescence quantum yield was developed and used for analysis of experimental data. The results indicated the existence of at least two different nonradiative relaxation mechanisms in NADH and FAD: a relatively slow nanosecond and a much faster picosecond ones. The analysis suggested that the increase of NADH fluorescence quantum yield with all alcohols concentration occurred mainly due to relatively slow nanosecond non-radiative and radiative relaxation mechanisms related with the change of conformation distributions, while the picosecond fluorescence quenching was found to have practically the same and conformation-insensitive value in water–monohydric alcohol mixtures. Similar conclusion was made for NADH in water–propylene glycol solutions where however a moderate decrease of the picosecond quenching rate was determined at high propylene glycol concentrations that was attributed to a slowdown of picosecond quenching under high viscosity conditions. In the case of FAD the analysis suggested that the dramatic rise of fluorescence quantum yield with alcohol concentration was mostly due to the conformation-sensitive picosecond quenching. This conclusion supports the known mechanism of the picosecond fluorescence quenching in FAD through electron transfer reaction in the π-stacked conformation between isoalloxazine and adenine moieties. Radiative decay times in NADH and FAD were estimated from experimental data and found to be about 10 ns and 20–30 ns, respectively.

Polarised fluorescence in FAD excited at 355 and 450 nm in water–propylene glycol solutions

Time-resolved polarised fluorescence in flavin adenine dinucleotide (FAD) in water–propylene glycol mixtures has been studied as a function of propylene glycol concentration using the TCSPC technique. The fluorescence was excited by picosecond laser pulses either at 450 nm or at 355 nm, the wavelengths that belong to the first and second FAD absorption bands, respectively. The global fit procedure was used for the determination of fluorescence decay times, corresponding weighting coefficients, initial anisotropy and rotational diffusion time from experiment. The experimental data manifested a double-exponential decay in the whole range of propylene glycol concentrations with the decay times τ 1 , τ 2 and weighting coefficients a 1 , a 2 . The coefficients a 1 and a 2 and the corresponding relative fluorescence quantum yields Q ( 1 ) r e l and Q ( 2 ) r e l were shown to change dramatically with addition of propylene glycol to the solution and demonstrated the domination of contribution of longer decay time at medium and high propylene glycol concentrations. The rotational diffusion time τ r o t manifested a sharp rise, up to 40 times with propylene glycol concentration that was practically proportional to solution viscosity. The initial anisotropy was determined to be equal to r 0 = 0.35 ± 0.03 and r 0 = 0.25 ± 0.02 under excitation at 450 nm and 355 nm, respectively. The dependence of fluorescence parameters on the solution viscosity and polarity was discussed taking into account FAD conformation distributions.

Thermal performance of water‐based brines as a heat carrier for ground heat exchanger under severely cold environments

AbstractThe aim of the present study is to investigate the performance of water‐based brine solutions in the ground heat exchanger (GHX) for space heating applications under severely cold climate conditions. The conventional ethylene glycol (EG) and propylene glycol (PG)‐based water solutions have been considered for investigation. For the closed‐loop vertical U‐tube GHX, a mathematically built model is developed for ambient temperature below 0°C. The thermal performance analysis of GHX is carried out for the variation in fluid flow rate and brine solutions for different mixture percentages of water in EG and PG. The percentage of the mixture and fluid flow rate varied from 25% to 60% and 0.2 to 0.6 LPS, respectively. GHX performance parameters, namely convective coefficient, pressure drop, borehole resistance, and GHX effectiveness are determined for both EG and PG brines. Better performance of GHX is noticed with EG brines as compared to PG brines for similar operating conditions. The drop in convective coefficient from 22% to 44% in the case of PG brines as compared to EG brines with the increase in mixture percentage from 25% to 60%, for the same operating conditions. The pressure drops decreased from 15% to 74% for EG mixture as compared to PG mixture at considered flow rate and mixture percentage. The effectiveness and overall borehole resistance were higher for EG as compared to the PG solution.

Preparation of Aqueous Propolis Extracts Applying Microwave-Assisted Extraction

Water-based propolis extracts usually contain up to 10-fold lower quantities of active ingredients due to poor solubility in water of propolis bioactive compounds when compared with ethanol-based extracts. Since ethanol-based extracts are of limited use, water-based extracts are preferred nowadays. The application of alternative extraction techniques should be evaluated to improve extraction efficiency. Aqueous propolis extracts were prepared using purified water and propylene glycol, 2-hydroxypropyl-beta-cyclodextrin and sodium bicarbonate aqueous solutions. A microwave-assisted extraction method was applied in cycles. The total concentration of hydroxycinnamic acids in aqueous propolis extract produced by four extraction cycles was determined to be 1502.1 ± 130.1 μg/mL and 20% propylene glycol, 10% 2-hydroxypropyl-beta-cyclodextrin and 5% sodium bicarbonate aqueous solutions, increasing the total concentration of hydroxycinnamic acids by 1.6, 1.7 and 1.9-fold, respectively. An application of microwave-assisted extraction method and the procedure of repeating extraction cycles reliably increased the quantity of hydroxycinnamic acids in aqueous propolis extracts. Similarly, the presence of propylene glycol, 2-hydroxypropyl-β-cyclodextrin and sodium bicarbonate increased the concentration of the hydroxycinnamic acids in propolis extracts.

Sulcatol and Fuscumol Increase Catches of Leptostylus asperatus and Styloleptus biustus (Coleoptera: Cerambycidae) in Ethanol-Baited Traps

Sulcatol and Fuscumol Increase Catches of <i>Leptostylus asperatus</i> and <i>Styloleptus biustus</i> (Coleoptera: Cerambycidae) in Ethanol-Baited Traps

Testosterone Sustained Release Microspheres for the Treatment of Fecal Incontinence

The objective of this study was to develop a testosterone sustained release formulation for the treatment of fecal incontinence. To suppress the initial burst release of testosterone, which can lead to systemic toxicity, we incorporated a washing step using an aminoalkyl methacrylate copolymer E solution or propylene glycol solution into a typical o/w emulsion method to prepare polylactic-co-glycolic acid microspheres. We used this method to develop a polylactic-co-glycolic acid microsphere formulation that shows sustained release of testosterone for up to one month. Not only did this formulation show a sustained release profile after administration into the intersphincteric groove in minipigs, it also increased both the anal pressure and mass of the external anal sphincter, while keeping systemic testosterone exposure low. Thus, this formulation successfully affected both the internal and external anal sphincters with a sufficient safety profile, deeming it a promising candidate treatment strategy for fecal incontinence.

Experimental and computer simulation of a molecular distillation process for the dehydration of tetramethylammonium hydroxide solution

Tetramethylammonium hydroxide pentahydrate (TMAH·5H2O) is easily decomposed when heated, which results in the difficulty of dehydration. In this study, a new process for dehydration of a TMAH propylene glycol solution using wiped-film molecular distillation was developed. The experiments were carried out to evaluate the effect of operating conditions on the performance of the dehydration with the operating temperature ranging from 65 °C to 90 °C, the operating pressure from 100 Pa to 2000 Pa and the mass flow rate from 36 to 162 g/min. The experimental results indicated that molecular distillation was capable of dehydrating TMAH solution to a water content of 0.65% from 5.82%. Then a modified Flash module in Aspen plus, which used the fitting factor and linear correlation between the simulated and experimental temperatures, was developed to simulate the dehydration process. The relative error between the modified simulated and experimental data is less than 5%, and the response surface methodology analysis was conducted to optimize the operating conditions. The optimal dehydration conditions were 85 °C, 100 Pa and 54 g/min feed flow rate, where the minimum water content in distilled solution is 0.43%. The results show that the process developed realizes a high efficiency of dehydration and prevents TMAH from thermal decomposition.

The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis

Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been shown to increase ketone bodies in patients with type 2 diabetes; however, the underlying mechanisms have not been fully elucidated. Here we examined the effect of the SGLT2 inhibitor dapagliflozin (1 mg/kg/day, formulated in a water, PEG400, ethanol, propylene glycol solution, 4 weeks) on lipid metabolism in obese Zucker rats. Fasting FFA metabolism was assessed in the anesthetized state using a [9,10-3H(N)]-palmitic acid tracer by estimating rates of plasma FFA appearance (Ra), whole-body FFA oxidation (Rox), and nonoxidative disposal (Rst). In the liver, clearance (Kβ-ox) and flux (Rβ-ox) of FFA into β-oxidation were estimated using [9,10-3H]-(R)-bromopalmitate/[U-14C]palmitate tracers. As expected, dapagliflozin induced glycosuria and a robust antidiabetic effect; treatment reduced fasting plasma glucose and insulin, lowered glycated hemoglobin, and increased pancreatic insulin content compared with vehicle controls. Dapagliflozin also increased plasma FFA, Ra, Rox, and Rst with enhanced channeling toward oxidation versus storage. In the liver, there was also enhanced channeling of FFA to β-oxidation, with increased Kβ-ox, Rβ-ox and tissue acetyl-CoA, compared with controls. Finally, dapagliflozin increased hepatic HMG-CoA and plasma β-hydroxybutyrate, consistent with a specific enhancement of ketogenesis. Since ketogenesis has not been directly measured, we cannot exclude an additional contribution of impaired ketone body clearance to the ketosis. In conclusion, this study provides evidence that the dapagliflozin-induced increase in plasma ketone bodies is driven by the combined action of FFA mobilization from adipose tissue and diversion of hepatic FFA toward β-oxidation.

New Property Averaging Scheme for Volume of Fluid Method for Two-Phase Flows With Large Viscosity Ratios

Abstract To predict liquid–gas two-phase flow, accurate tracking of the evolving liquid–gas interface is required. Volume-of-fluid (VoF) method has been used for computationally modeling such flows where a single set of governing equations are solved for both phases along with an advection equation for the volume fraction. Properties in each cell are determined by a linear weighted average of the properties of the two fluids based on the phase fraction. While the method predicts water–air flows well, the predictions tend to deviate significantly from experiments for liquids with high viscosity. A new property averaging technique is proposed, which is shown to provide accurate results for high viscosity liquids. Computational predictions using open-source VoF solver inter-foam and the proposed method are compared with experimental data for multiple two-phase applications. Four different problems, viz., suspended drop, jet breakup, drop impact on thin films, and on liquid pools, are considered to extensively validate the new method. Data for aqueous solutions of propylene and ethylene glycol are used to cover a range of surface tension (72–36 mN/m) and viscosities (1–40 mPa·s). For all cases, the modified VoF solver is observed to perform significantly better than the original VoF method. It reduces spurious currents in simulations of a drop suspended in the air. For the cases of a drop impacting on a pool and during drop generation from liquid jets, the time progression of the surface tension governed dynamics is improved from the slower estimate of the inter-Foam solver.

Pressurized aqueous solutions of deep eutectic solvent (DES): A green emergent extraction of anthocyanins from a Brazilian berry processing by-product

Deep eutectic solvents (DES) are emergent solvents with high extractability of bioactive compounds. Therefore, anthocyanin rich-fractions were recovered from jaboticaba peels by combining aqueous solutions of DES and pressurized liquid extraction (PLE). The extraction occurred at 10 MPa, 12 min, with conditions optimized through response surface methodology: 47% DES concentration, 90 °C, and 5.3 mL/min flow rate. PLE with different DES (choline chloride combined with propylene glycol or malic acid) solutions were compared to conventional solvents (water and acidified water) concerning yield, thermostability, antioxidant, anti-diabetic, and anti-obesity activities. DES solutions presented anthocyanin yields up to 50% higher than conventional solvents. ChCl:Ma, with the highest anthocyanin stability (Ea = 77.5 kJ.mol−1), was a promising solvent concerning color, anti-diabetic and anti-obesity potential. Environmental analysis by Green Certificate and EcoScale indicated PLE with DES solutions is a green and efficient approach to recover anthocyanin from jaboticaba peel, providing useful extracts.

Remote Loading of Gas Bubbles into Polylactic Acid Microcapsules Creates Acoustically Active Janus Particles.

Polymeric microcapsules (MCs) are biocompatible agents used in biomedical applications such as drug delivery and in vivo imaging. We have discovered a method of remotely loading air into polylactic acid (PLA)-based MCs with an aqueous core. When the microcapsules are suspended in high content glycerol and propylene glycol solutions, changes in gas solubility cause bubbles to nucleate within the core through an "Ouzo-like" effect. The resulting bubble displaces the internal fluid of the MCs, but small molecules are retained in their interior. The residual content does not homogeneously distribute; rather, it localizes to one specific location, creating gas-filled Janus particles.

Does the technical methodology influence the quality attributes and the potential of skin permeation of Luliconazole loaded transethosomes?

Luliconazole (LCZ) is a novel topical imidazole medication with broad-spectrum antifungal activity. Unfortunately, the high potential of LCZ for topical antifungal activity is hampered by its low solubility and low skin permeability that required long-term therapy with frequent administration for a full recovery. So, this study aimed to enhance the skin permeation of LCZ through its loading in ultradeformable nanovesicles, transethosomes (TE), using either ethanol injection sonication or thin-film hydration methods. The prepared nanovesicles were characterized for vesicles size, zeta potential, entrapment efficiency, and in vitro drug release. Moreover, the ex vivo skin permeation and deposition via rat skin were estimated. In vitro characterization of the LCZ-TE displayed that the average vesicles size prepared by the ethanol injection method was 246.3 ± 0.56 versus 62.75 ± 0.16 nm with a thin-film method. Also, the zeta potential and encapsulation efficiency were 36.3 ± 0.81 mV and 82.35 ± 3.68% versus 49.4 ± 0.67 mV and 93.85 ± 1.78% in the ethanol injection sonication and thin-film hydration, respectively. Furthermore, the deposited percentage of LCZ in the skin by TE formulation prepared by thin film hydration (54.79 ± 5.23%) is more than 2-fold the percentage of LCZ solution in propylene glycol (PG) (25.26 ± 2.84%) and 1.5 fold more than TE prepared by ethanol injection (35.65 ± 4.354) due to the enhanced skin permeation and deposition of LCZ-TE. These results revealed the superiority of the thin film hydration technique in the enhancement of the quality attributes of the prepared nanovesicles and pointed out their potential in the treatment of fungal infections of the skin.

Molecular dynamics study on the mechanism of nanofluid coolant's thermal conductivity improvement

With an increase of the heat load of internal combustion engines, the amount of heat that needs to be taken away from the cooling oil chamber is increasing. However, the thermal conductivity of existing coolants is insufficient to discharge this heat out of the internal combustion engine. Nanofluids have higher thermal conductivities than conventional fluids, so they can be considered a solution to the above problem. In this paper, different volume fractions of Cu nanoparticles are added into different coolant solutions, ethanol, ethylene glycol (EG), and propylene glycol (PG), to form alcohol nanofluids. The effect of concentration on the thermal conductivity of ethanol / EG / PG solution was analyzed by molecular dynamics method, and the thermal conductivities of the systems after adding Cu are also calculated and analyzed. It is found that the temperature gradients of the ethanol/EG/PG–water systems decrease gradually with an increase of water content, resulting in an increase of thermal conductivity. The increase of thermal conductivity is mainly due to an adsorption layer of solution atoms on the surfaces of the Cu nanoparticles. 1.5% and 3% volume fractions of Cu nanoparticles can improve the thermal conductivities of the three alcohol solutions by 12.8%, 27.3%, and 16.1%, respectively. Through an analysis of the adsorption layer on the surfaces of the Cu nanoparticles, it is found that the adsorption layer is stratified; that is, water molecules are located in the outer layer, alcohol molecules are in the inner layer, and the stratification of the adsorption layer is different in the different alcohol solutions. In the three alcohols, the delamination sites of the Cu nanoparticles are 2 nm for the ethanol system, 1.8 nm for the PG system, and 1.5 nm for the EG system. The closer the stratification position is to the nanoparticles, the better the mixture of water and alcohol molecules in the adsorption layer, and the higher the thermal conductivity. These results can provide an important reference for the application of nanofluids in internal combustion engines.

ИССЛЕДОВАНИЕ ПРОТИВООБЛЕДЕНИТЕЛЬНОЙ ЖИДКОСТИ ОПТОЭЛЕКТРОННЫМ РЕФРАКТОМЕТРОМ

This work highlights the development of optoelectronic refractometer to study anti-icing liquids. Determining the composition authenticity and the flow rate of these liquids has always been a relevant task for the airport maintenance units, engaged in the processing of the aircraft body. The paper presents the objects of research: aqueous solutions of ethylene glycol and propylene glycol, which make up 95% of the composition of liquids of TYPE I, TYPE II, TYPE IV. The structural diagram and appearance of an optoelectronic refractometer are given. The results of measurements of the temperature dependences of the refractive index n(t) for solutions of ethylene glycol and propylene glycol in the temperature range from 12 °C to 100 °C and for concentrations from 0% to 100% are obtained. The spectra of ultraviolet optical transmission in ethylene glycol and propylene glycol of high purity in the wavelength range λ 210–320 nm with an error not worse than T = 0.5% are studied. The technical characteristics of an optoelectronic refractometer are given.

In vitro larvicidal activity of ivermectin and povidone-iodine against Oestrus ovis.

To assess the in vitro larvicidal activity of ivermectin and povidone-iodine (PVP-I) against Oestrus ovis, the most frequent cause of external ophthalmomyiasis. L1 O. ovis larvae were collected from the nasal boots of sheep slaughtered in local abattoirs and transferred onto Petri dishes containing mucosal tissue (25 larvae/dish). The larvicidal activity of the following formulations was tested: 1% ivermectin suspension in balanced sterile saline solution (BSSS), 1% ivermectin solution in propylene glycol, propylene glycol, 0.6% PVP-I in hyaluronic acid vehicle (IODIM®), and combination of ivermectin 1% solution and 0.6% PVP-I. One mL of each formulation was added to different Petri dishes containing the larvae. The time needed to kill the larvae was recorded. 893 larvae were tested. The median time needed to kill the larvae was 46, 44, 11, 6, and 10 minutes for Iodim®, ivermectin 1% suspension, propylene glycol, ivermectin 1% solution, and a combination of ivermectin 1% solution with 0.6% PVP-I, respectively. Kaplan-Meyer analysis disclosed that the survival curves were significantly lower in samples treated with ivermectin 1% solution, ivermectin 1% solution + 0.6% PVP-I, and propylene glycol than in samples receiving other treatments or BSSS. In this in vitro study, ivermectin 1% solution in propylene glycol, ivermectin 1% solution + 0.6% PVP-I, and propylene glycol alone showed a good, relatively rapid larvicidal activity against O. ovis larvae. Further experimental and clinical studies are necessary to establish whether, or not, these formulations may be considered as potential candidates for the topical treatment for external ophthalmomyiasis caused by O. ovis.

Broadband dielectric relaxation spectroscopy and molecular dynamics simulation study of paracetamol-propylene glycol solutions

The complex permittivity ε*(ω) = ε′(ω) - ε“(ω) was studied for a series of paracetamol (PCM) – propylene glycol (PG) solutions over the broadband frequency range of 20 Hz to 20 GHz at different temperatures ranging from 293.15 K to 323.15 K. Measurements of the complex permittivity were carried out using Agilent Precision LCR meter E4980A with Agilent 16452A liquid test fixture (for 20 Hz to 2 MHz frequency region) and Anritsu Shockline Vector Network Analyser MS46322A with DAK-3.5 probe (for 200 MHz to 20 GHz frequency region). Obtained broadband frequency dependent dielectric data were analyzed to explore the interaction mechanisms and structural behavior of PCM and PG molecules in mixed state in terms of molar PCM concentration and temperature variation. Temperature dependent dc conductivity response of all solutions exhibited Arrhenius behavior from which activation energy was calculated. Microwave complex permittivity data were fitted to the Cole-Davidson model in order to determine dipolar relaxation parameters of the solutions. Dielectric constant and dielectric loss values at a spot frequency of 2.45 GHz were utilized to determine the microwave heating parameters and analyzed in view of its suitability for the microwave dielectric heating in pharmaceuticals. Molecular dynamics simulation study for selected concentrations of PCM in PG was also conducted in order to understand the actual mechanism of H-bonding interactions in the solutions and to justify the inferences derived from the experimental results.

Effect of composition of mono/di-hydroxy organic compounds and temperature on the aggregation behavior and physico-chemical properties of polyvinyl alcohol + TTAB mixture

Herein, the aggregation manners of polyvinyl alcohol (PVA) with tetradecyltrimethylammonium bromide (TTAB) in alcohols/diols media containing various concentrations and at several temperatures were performed using the conductivity measurement technique. Different physico-chemical parameters, such as critical micelle concentration (CMC), fraction of bound counter ions (β) and thermodynamic properties (ΔGo m, ΔHo m, ΔSo m, and ΔCo m) for the TTAB + PVA mixture in aqueous solutions of EtOH (EtOH), 1-propanol (1-PrOH), ethylene glycol (EG), and propylene glycol (PrG), have been determined. The CMC values were found to undergo a decrease in 1-PrOH in comparison to the values obtained in aqueous media, but in EtOH, the CMC value firstly decreases, touches the lowest point, and then exhibits an upsurge with further increase of the percentage of EtOH. The observed greater CMC values in diols media disclose that the micelle formation of TTAB + PVA mixture is delayed in the manifestation of diols. The CMC values of TTAB + PVA mixture have also been observed to vary with the change of study temperature. The negative values of ΔG0 m were obtained for all circumstances suggesting a spontaneous aggregation phenomenon of TTAB + PVA system. The values of ΔH 0 m and ΔS0 m dictate that the PVA molecule interacts exclusively with TTAB through the formation of hydrogen bonding, ion-dipole, and hydrophobic interaction. Furthermore, the standard molar heat capacity (ΔC 0 m), compensation temperature (T c), intrinsic enthalpy gain (ΔH 0,* m), and the thermodynamic properties of transfer (ΔG 0 m.tr, ΔH 0 m.tr. and ΔS 0 m.tr.) for the studied system were assessed and demonstrated with appropriate explanations.