This paper presents a synchronous proportional derivative (PD) control method using a time delay estimator (SPD-TDE) for a four-degree-of-freedom (DOF) parallel robot in practice. The proposed control is a method that is developed from a synchronous PD control method combined with a time delay estimator to guarantee the tracking objectives and synchronous requirements of the robot. Firstly, the synchronous PD control method is designed by defining cross-coupling errors. A cross-coupling error is determined by incorporating the tracking error and deviation of tracking error among two adjacent joints or synchronous errors. Then, the asynchronous problem between the kinematic chains is solved and guarantees that the goal of synchronicity is achieved. Consequently, to improve the tracking performance of the robot, a time delay estimator is used to estimate and eliminate the uncertainty components of the system, such as modeling errors and actuator faults. In addition, the Lyapunov theory is also used to demonstrate the stability and robustness of the proposed control method. Finally, a testbench 4-DOF parallel robot is built, and the controllers are embedded in the control board from MATLAB Simulink using the Waijung block set library to operate the robot preset trajectory tracking. The experimental results of the proposed control method for the 4-DOF parallel robot are compared with those obtained using other controllers to prove its effectiveness.