Index Properties Research Articles

Tests for almost stochastic dominance

We introduce a 2-dimensional stochastic dominance (2DSD) index to characterize both strict and almost stochastic dominance. Based on this index, we derive an estimator for the minimum violation ratio (MVR), also known as the critical parameter, of the almost stochastic ordering condition between two variables. We determine the asymptotic properties of the empirical 2DSD index and MVR for the most frequently used stochastic orders. We also provide conditions under which the bootstrap estimators of these quantities are strongly consistent. As an application, we develop consistent bootstrap testing procedures for almost stochastic dominance. The performance of the tests is checked via simulations and the analysis of real data.

The radiative properties in the near-infrared band of crude oil emulsion dispersed in the seawater

The complex refractive index and radiative properties of crude oils are essential parameters for remote sensing, which is paramount for accurately and quantitatively detecting marine oil spills. In this study, the complex refractive index in the near-infrared band of crude oil from Daqing Oilfield is measured by the combined transmission - KK transformation method, and the absorption spectral features are analyzed. A modified-Mie method is employed to calculate the radiative properties of crude oil droplets immersed in an absorbing medium, and the impact of medium absorption is examined. Furthermore, the spectral absorption/scattering coefficient and scattering phase function of the oil-in-water (OW) emulsion dispersed in seawater are calculated, and the corresponding correlations between the radiative properties and chemical compositions of the crude oil are analyzed. The research reveals that the differences in the components of crude oil and seawater result in variations in the absorption peaks/troughs in their absorption spectra curve, which subsequently cause a gradual increase/decrease in absorption and scattering coefficients as the volume fraction of emulsion increases. The quantitative correlations of the absorption/scattering coefficient with the volume fraction of OW emulsion are presented, which are significant for improving the quantification monitoring of emulsified oil spills and identifying different types of pollutants.

Psychometric evaluation of the Self-Report Habit Index for assessing habitual e-cigarette use behavior in high school adolescents

BackgroundE-cigarettes are the most-used nicotine product among adolescents, but limited psychometrically-sound, e-cigarette-relevant measures exist for adolescents. We examined psychometric properties of the Self-Report Habit Index (SRHI) for assessing adolescents’ habitual e-cigarette use. MethodsDuring Fall 2022, 4855 students from eight Connecticut high schools completed an anonymous survey. The analytic sample comprised 491 students who reported past-month e-cigarette use and completed the SRHI (Age M=15.94, SD=1.24 years, 56 % female, 37.1 % Hispanic, 57.6 % White). We examined the SRHI’s latent factor structure; internal reliability; measurement invariance and between-groups differences (e.g., nicotine vs. nicotine-free vaping); and associations with total e-cigarette flavors used in the past month, past-30-day vaping frequency, and e-cigarette dependence. ResultsThe SRHI’s 6-item, 1-factor structure was confirmed. Internal reliability was excellent. The SRHI was scalar invariant for all subgroups tested. Nicotine (vs. nicotine-free) and daily (vs. non-daily) e-cigarette use were associated with greater habitual e-cigarette use behavior. In adjusted models, habitual e-cigarette use was associated with using more e-cigarette flavors, vaping more frequently, and greater e-cigarette dependence. Habitual e-cigarette use incrementally accounted for variance in past-month flavors used and vaping frequency beyond dependence. ConclusionsThe SRHI evidenced solid psychometric properties for assessing habitual e-cigarette use behavior among high school students. Relationships between habitual use and frequency of use, e-cigarette flavors, and dependence might be expected as these constructs are associated with the three characterizing features of habitual behaviors: frequent repetition, cue-driven elicitation, and automaticity. Future prospective research can clarify the temporal ordering of habitual e-cigarette use and dependence in adolescents.

Synthesis, DFT studies on a series of tunable quinoline derivatives.

The synthesis, Density Functional Theory (DFT) calculations, and photo physical characteristics of a range of quinoline derivatives have been described in the present work. Initially, the innovative derivatives are synthesized through the cyclization of 2-amino-5-nitrobenzophenone with either acetyl acetone or ethyl acetoacetate, followed by reducing the nitro group to an amine. Subsequently, these compounds undergo an acid-amine cross-coupling reaction. The investigation shows the DFT and photo physical properties of these substances. It is noteworthy that compound 6z exhibits the most remarkable Stokes shift among the fluorophores investigated. Furthermore, the research also provides insights into the electrophilicity index, Electronegativity, chemical potential, chemical hardness and softness properties. These properties are determined by utilizing Density Functional Theory (DFT) calculations and evaluating electron potential efficiency and using computational methods Time-Dependent Density Functional Theory (TD-DFT) to predict absorption spectra in molecules at the B3LYP/6-31G'(d,p) level/basis.

Mechanical and hydraulic properties of unsaturated layered pyroclastic ashes in landslide-prone areas of Campania (Italy)

Air-fall pyroclastic soil deposits usually display a loose fabric composed of alternating layers of ashes and pumices. Such deposits, when lying on steep slopes, represent a major geohazard due to the occurrence of landslides. This is the case of the carbonate massifs in Campania (southern Italy), a wide landslide-prone area of approximately 400 km2 covered with pyroclastic soils. In such cohesionless deposits, the additional shear strength provided by soil suction in unsaturated conditions is important for ensuring slope stability and can be jeopardized by soil wetting during rainwater infiltration. This paper provides a comprehensive view of the hydraulic and shear strength characteristics of different layers of pyroclastic deposits at different sites in Campania, revealing a broad view of their similarities and differences. To that end, some datasets from previous studies and novel data are gathered, linking the index properties, the hydraulic behavior of the soils and the contribution of suction to the shear strength of the studied materials. Two types of ashes at different positions within the stratigraphic sequence are identified: ashes interbedded between pumice layers, where landslide failure surfaces usually occur, and altered ashes in contact with the bedrock, which affects water leakage from the overlying soil profile. The former show quite uniform characteristics, and this allowed testing some predictive models for the assessment of the unsaturated shear strength of pyroclastic ashes in the absence of direct measurements. In contrast, the latter may exhibit significantly different behaviors, with great variability in hydraulic and mechanical properties.

Transparent and High-Refractive-Index Titanium Dioxide/Thermoplastic Polyurethane Nanocomposites.

Transparent nanocomposite films made of surface-modified titanium dioxide nanoparticles and thermoplastic polyurethane are prepared via film casting approach showing enhanced refractive indexes and mechanical properties. Two different sets of composites were prepared up to 37.5 wt % of inorganic nanoparticles with a diameter <15 nm, one set using particles capped only with oleic acid and a second one with a bimodal system layer made of oleic acid and mPEO-5000 as coating agents. All of the composites show significantly enhanced refractive index and mechanical properties than the neat polymeric matrix. The transparency of nanocomposite films shows the excellent dispersion of the inorganic nanoparticles in the polymeric matrix avoiding aggregation and precipitation phenomena. Our study provides a facile and feasible route to produce transparent nanocomposite films with tunable mechanical properties and high refractive indices for various applications.

Highly conductive polymer electrodes for polymer light-emitting diodes

Organic light-emitting diodes (OLEDs) offer the advantage of flexibility; however, the use of traditional transparent anode ITO limits further extension of their flexible characteristics. In this study, we propose employing an polymer polybenzodifuranedione (PBFDO) as a flexible transparent anode instead of the rigid ITO. To address the issue encountered during the PBFDO solution spin-coating process, we introduced n-butanol into the PBFDO conductive solution to reduce its viscosity and freezing point by modulating intermolecular hydrogen bonding interactions. Consequently, high-quality PBFDO films with high conductivity, superior transmittance, and low surface roughness were successfully obtained via spin-coating. Moreover, due to its proper work function, regular molecular stacking, and low refractive index properties, PBFDO electrode facilitate efficient carrier injection and transport as well as photon extraction. The resulting device utilizing a PBFDO anode combined with Super Yellow as the light-emitting layer exhibited excellent performance characteristics including a normal threshold voltage of 2.6 V and a maximum luminous efficiency of 12.8 cd A−1 comparable to that device based on the ITO electrode. Furthermore, flexible device also achieved satisfactory performance (7.7 cd A−1) when using the PEN substrate.

Impact of microplastics on strength parameters of clayey, Sandy, silty soil: A comparative assessment

The comparative assessment of a variety of microplastic contamination on various soil types hasn't been extensively explored in existing literature. The present study focuses on the comparative analysis of the impact of environmentally relevant concentrations of LDPE, HDPE, and PVC microplastic contamination (2 %, 4 %, and 6 %) on index properties and strength parameters of sandy, silty and clayey soil types at varying observation days 5,10,15,20,25, and 30 days. Extensive experimental investigations are carried out to understand the effect of contamination on moisture content, specific gravity, liquid limit, plastic limit, plasticity index, optimum moisture content, maximum dry density, and shear strength parameters of the respective soil type. It is observed that the depletion in Atterberg's limits is found more in the case of clayey soil as compared to silty soil because clayey soils consist of large specific surface areas leading to van der Waals force of attraction being the predominant force between particles, compared with silty soil which is affected by microplastic addition leading to decrease in net attractive forces. In the case of clayey soil maximum depletion of liquid limit up to 168 %, plastic limit up to 33 %, plasticity index (136 %), and optimum moisture content (9.04 %) is observed for PVC microplastic. The deduction in maximum dry density values is observed more for sandy soil (0.59 g/cc) followed by silty soil (0.21 g/cc) and clayey soil (0.12 g/cc). The maximum depletion of moisture content(delta-8 %), shear strength (delta-0.89 kg/cm2), and maximum dry density (delta-0.44 g/cc) is observed in the case of sandy soil for PVC and LDPE microplastic contamination. Significant depletion in optimum moisture content is observed in the case of clayey soil (9.57 %) compared to sandy (5.62 %) and silty soil (5.3 %). An increase in cohesion is observed for sandy soil (0.09 kg/cm2) and a decrease for clayey (0.19 kg/cm2) and silty soil (0.19 kg/cm2). The angle of internal friction is reduced in the case of clayey soil (∆-14.380) followed by silty soil (∆-11.230) and sandy soil (∆-11.020). For silty soil maximum depletion of specific gravity(delta-1.06) and cohesion (0.192 kg/cm2) is observed for LDPE and HDPE microplastic. The sandy soil type is most affected due to microplastic contamination irrespective of the type of microplastic contamination followed by clayey soil and the silty soil type is least affected. The maximum overall shear strength is reduced due to microplastic contamination in all the soil types.

Virtual reality and functional training effect on contractile properties of lower leg muscles and postural stability

Purpose. Tensiomyography is a noninvasive and reliable method to identify the differences in skeletal muscle responses. Poor lower leg muscles cause poor postural stability, leading to the risk of injury in athletes. The study aims to investigate the aftereffect of a six-week virtual reality environment and functional training program on the contractile properties of lower-leg muscles and postural stability index. Material and methods. A comparative pre-test and post-test study design was selected for this study. Twenty-four male athletes were taken part in the study. The participants were randomly divided into a virtual reality intervention-training group (n=12) or a functional training group (n=12). The virtual reality environment training was provided using the CAREN integrated virtual reality system with a D-flow application from Motek. Functional training for static and dynamic postural stability was performed with various open and closed-eye exercises in the physical therapy lab. The contractile properties of lower-leg muscles were measured using tensiomyography. The postural stability index was assessed using a stadiometer. The assessments were performed before and after six weeks of training. A paired sample t-test was used to determine differences between pretest and posttest intervention outcome measures, and sample t-test was also applied to determine differences between groups after six weeks of training. Results. Results indicated significant differences between pretest and posttest measurement in virtual reality training group for displacement (t=2.81, p=.043), (t=-6.92, p=&lt;.001) in gastrocnemius lateral and medial muscle respectively, and sustain time (t=2.29, p=.042) in souls muscle. The postural stability with close eye was significant (t=2.61, p=.024). The functional training group showed significant differences for sustain time (t=-18.86, p=&lt;.001) in gastrocnemius lateral, and relaxation time (=3.24, p=.008), delay time (t=3.07, p=.011), and sustain time (t=-19.74, p=&lt;.001) in gastrocnemius medial, and sustain time (t=3.17, p=.009) in souls muscle. The postural stability was having insignificant differences. Conclusion. The virtual reality environment and functional training, help to improve performance, and tensiomyography could be used to assess and evaluate the parameters that could be helpful for optimizing training load in the performance enhancement process of athletes.

Scalable chlorination of polypropylene for structural modification and flame retardancy as coating materials of insulation cable

ABSTRACT Chemical precipitation route has been demonstrated for in-situ chlorination of polypropylene and structural modification to integrate flame retardancy along with facile processing parameters, i.e. optimum melt flow index and mechanical properties. Thus, obtained chlorinated polypropylene (Cl-PP) was characterized for optimized composition and degree of chlorination, chemical structure, morphology, physical properties with the help of infra-red spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscope (SEM), melt flow index and other standard methods. The analytical results revealed the 74% chlorination of polypropylene chain increased with the molecular weight, comparable melt flow index and improved flame retardancy from V2 to V0 grade on UL-94 scale due to reduced heat release rate and improved limiting oxygen index from 17.5 to 27.1 due to structural changes and induced polycrystallinity. The evolved features of PP were explained on the basis of synergistic interaction, evolved crystallinity, size reduction and functionality during chemical treatments and reprecipitations. Further, the obtained Cl-PP was explored as the coating material for insulation of cables with electric insulation and durable properties.

Psychometric Evaluation of the Insomnia Severity Index in Nurses

ABSTRACT Objectives Examine psychometric properties of the Insomnia Severity Index (ISI) in a sample of nurses. Method In a sample of day shift nurses (N = 289), a confirmatory factor analysis (CFA), convergent and discriminant validity analyses, and a test–retest reliability analysis were performed. Results CFA showed that a two-factor model provided the best fit. The ISI had moderate to poor convergent validity with sleep diary parameters, and moderate convergent validity with the Sleep Condition Indicator (r = -.66), Pittsburgh Sleep Quality Index (r = .66), and PROMIS Sleep-Related Impairment measure (r = .67). The ISI demonstrated good discriminant validity with the measures Composite Scale of Morningness (r = −.27), Nightmares Disorder Index (r = .25), PTSD Checklist for DSM-5 (sleep items removed; r = .32), and Perceived Stress Scale (r = .43). The ISI had weaker discriminant validity with the PHQ-9 (r = .69) and Generalized Anxiety Disorder Screener (r = .51). The ISI demonstrated a good test–retest reliability (ICCs = .74–.88). Conclusions The ISI is a psychometrically strong measure for the assessment of insomnia severity in day shift nurses. Overlap with psychological symptoms, primarily anxiety and depression, suggests caution while interpreting these constructs.

Characterization of polarization properties of colorectal cancer using decomposition Mueller matrix method

Rectal cancer is the third most prevalent cancer diagnosed and is traditionally screened using colonoscopy. Meanwhile, polarization characteristic measurement has emerged as an attractive alternative in recent years owing to its deep analysis of the structure of samples and non-invasive nature. Accordingly, this study employed the Mueller matrix decomposition method to measure the effective optical parameters of 100 slices from 20 healthy rectal tissue samples and 100 slices from 20 cancerous rectal tissue samples. The mean values and expression levels of the linear birefringence, circular birefringence, linear dichroism, circular dichroism, and depolarization index properties of the samples were compared using t-tests and ANOVA tests. The experimental results showed that the linear birefringence, orientation angle of linear dichroism, and values of linear dichroism and circular dichroism showed significant differences between the different tissue types. Thus, these parameters may serve as useful biomarkers for the diagnosis of rectal cancer.

Analisis Perubahan Volume pada Timbunan Tanah Lempung Berdasarkan Nilai Batas Susut (SNI 3422:2008)

Sedimentation has continuously resulted in siltation of the port of Pelabuhan Perikanan Samudera (PPS) Lampulo located in Kuta Alam District, Banda Aceh City. The dredged soil collected outside the port area visually indicates clay soil. In addition to the low bearing capacity and high plasticity, the effect of water on clay is high swelling and shrinkage. One of the prominent behaviors that cause major damage to structures built on clay is associated with volume decrease i.e., shrinkage in saturated compressible clay soil when water get evaporated. Shrinkage in clay will result in volume changes. The purpose of this research is to calculate the volume changes in mound of clay soil based on shrinkage limit values using SNI 3422:2008. The soil sample used is an undisturbed sample (UDS) originating from the dredging area of the port of PPS Lampulo. The test consists of water content, specific gravity, liquid limit, plastic limit, shrinkage limit and grain size distribution using the SNI method. Based on the results of the index properties test, according to AASHTO the soil sample belongs to group A-7-5 which means it is a clay soil with a GI value greater than 20, so it is considered poor as a subgrade soil. According to USCS, the soil belongs to the CH classification, which means clay soil with high plasticity, so it has a large potential for expansion and shrinkage. Based on SNI 3422:2008, the average shrinkage limit (SL) is 21.21%, the average shrinkage ratio (R) is 2.27% and the average linear shrinkage (LS) is 9.65%. With an average volume change (VC) value of 35.59%, the shrinkage volume of soil embankment of the dredging area of the port of PPS Lampulo is 32,438.85 m3 compared to its initial volume (91,145.97 m3). Therefore, the shrinkage limit is an important parameter for calculating the volume shrinkage in mound of soil due to the soil type is clay with high plasticity.

3D printed structures with a tailored refraction index fabricated with an acrylate resin modified by a conjugated polymer

Resins for 3D printing usually do not present suitable photoluminescence for application in optoelectronic devices. Herein, a conjugated polymer (PFeBSe) with luminescent and high refraction index properties was synthesized and used to modify an acrylate-based resin. This PFeBSe copolymer presents an ester-based side group that enhances the compatibility with the acrylate resin, resulting in a homogeneous polymeric blend. Further, the modified resin was employed with the 3D digital light processing (DLP) technique to produce luminescent guiding structures with a tailored refraction index. To maintain the processing parameters of the acrylate resin, the blending with the conjugated polymer was kept at a low concentration in the range of 5% to 15% (v/v). The blending changed the refraction index of the pristine acrylate from 1.49 to 1.51 (5% v/v) and 1.56 (15% v/v), respectively. Moreover, the resulting structures present a low extinction coefficient at the wavelength region above 600 nm. These characteristics enable the fabrication of structures with controllable forms and dimensions that can be used in the design of advanced sensors and optoelectronic devices.

Exploring the properties of the Intersectional Discrimination Index — Major in Canadian Veterans with chronic pain

LAY SUMMARY In this study, the utility of a new self-report scale to capture experiences of discrimination or violence among a sample of Canadian military Veterans with chronic pain was evaluated. The Intersectional Discrimination Index — Major (InDI-M) was administered through an online survey along with other scales to measure experiences of pain, mood disorder, and functional interference. Results indicate that the InDI-M appears to measure both experiences of interpersonal violence and of systemic inequity, although some problems were identified when using the scale in this sample of predominantly white male Veterans. The InDI-M might be a useful research tool for exploring effects of interpersonal violence on pain and mental health but less so for exploring experiences of systemic inequity in military Veteran health research.

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Fexofenadine

In this monograph, the potential use of methods based on the Biopharmaceutics Classification System (BCS) framework to evaluate the bioequivalence of solid immediate-release (IR) oral dosage forms containing fexofenadine hydrochloride as a substitute for a pharmacokinetic study in human volunteers is investigated. We assessed the solubility, permeability, dissolution, pharmacokinetics, pharmacodynamics, therapeutic index, bioavailability, drug-excipient interaction, and other properties using BCS recommendations from the ICH, FDA and EMA. The findings unequivocally support fexofenadine's classification to BCS Class IV as it is neither highly soluble nor highly permeable. Further impeding the approval of generic equivalents through the BCS-biowaiver pathway is the reference product's inability to release ≥ 85 % of the drug substance within 30 min in pH 1.2 and pH 4.5 media. According to ICH rules, BCS class IV drugs do not qualify for waiving clinical bioequivalence studies based on the BCS, even though fexofenadine has behaved more like a BCS class I/III than a class IV molecule in pharmacokinetic studies to date and has a wide therapeutic index.

Enhancing Index and Strength Properties of Black Cotton Soil Using Eco Friendly Material: GGBS

This research investigates the efficiency of utilizing Ground Granulated Blast Furnace Slag (GGBS) for soil stabilization, aiming to improve index and strength properties and address environmental sustainability through waste utilization. Various laboratory tests, including compaction, Atterberg limits, and unconfined compressive strength evaluations, were conducted on soil samples of Hingoli district amended with GGBS at different ratios. The results reveal significant enhancements in engineering properties, indicating the potential of GGBS in soil stabilization practices. The findings underscore the economic and environmental benefits of incorporating GGBS into soil stabilization techniques, offering a sustainable solution for both soil improvement and waste management in construction projects. This study contributes to the advancement of sustainable engineering practices by demonstrating the effectiveness of waste utilization in enhancing soil performance and mitigating environmental impacts. Keywords-: GGBS, Atterberg Limit, Hingoli, Unconfined Compressive Strengtht, Speicfic Gravity

Compact metamaterial-based single/double-negative/near-zero index resonator for 5G sub-6 GHz wireless applications

The concept, performance, and analyses of distinctive, miniaturized metamaterial (MTM) unit cell addressing the forthcoming Sub 6 GHz 5G applications are presented in this paper. Two circular split-ring resonators (CSRR) with two parallel rectangular copper elements in front of the design and a slotted square element in the background make up the suggested metamaterial. It has a line segment with tunable features that is positioned in the center of the little ring copper structure. The suggested design offers a significant operating frequency band of 220 MHz together with a resonance of transmission coefficient S21 at 3.5 GHz. Furthermore, in two (z & x) principal axes of wave propagation, wide-range achievement, single/double-negative (S/DNG) refractive index, negative permittivity, and near-zero permeability properties were demonstrated. Through varying central slotted-strip line length, resonance frequencies can be selectively altered. Moreover, the metamaterial has overall dimensions of 9 × 9 mm2 and is composed on a Rogers 5880 RT substrate. In order to create the suggested MTM's equivalent circuit, which shows similar coefficient of transmission (S21), a proposed design’s numerical simulation is carried out in the CST micro-wave studio. This simulation is after that put to comparison with manufacturing of the design.

Pollution assessment and index properties of Okpulor soils, Rivers State, Nigeria: geochemical characterization, geotechnical and geoenvironmental implications

This study assessed soil pollution and index properties in Okpulor through geochemical, geotechnical, and geoenvironmental analyses. Twenty samples, comprising 14 surface and 6 shallow subsurface ones, underwent geochemical analysis for heavy metals (Fe, Cr, Cu, Zn, Ni, and Pb). Five geochemical indices, including the Geoaccumulation Index (Igeo), Enrichment Factor (EF), Contamination Factor (CF), Metal Pollution Index (MPI), and Potential Ecological Risk Index (PERI), were utilized. Simultaneously, six subsurface samples underwent geotechnical analysis for Natural Moisture, Grain Size, Specific Gravity, Bulk Density, and Atterberg Limits, following Unified Soil Classification System (USCS) and American Association of State Highway and Transportation Officials (AASHTO) guidelines. The Igeo highlighted significant heavy metal contamination in Okpulor soils, particularly Cd. EF values exceeding 1.5 underscored a strong anthropogenic influence, with CF indicating Cd's substantial contribution to overall contamination. PERI underscored the ecological risks associated with Cd contamination. Natural moisture content, ranging from 18.21% to 21.45%, indicated a notable presence of water in the soil during the dry season, potentially leading to increased leaching and migration of water-soluble contaminants. Bulk density values suggested moderate to lightly packed soils, impacting porosity and permeability, and influencing contaminant movement. Atterberg limits indicated low soil plasticity, impacting moisture retention and contaminant behaviour. Grain size analysis revealed poorly graded soils with a close sand-to-clay ratio, affecting water drainage. These geotechnical properties and heavy metal contamination reveal the intricate interplay between soil characteristics and contamination risks in the Okpulor area, emphasizing the need for targeted interventions to safeguard the environment.

Endoscopic scoring indices for assessing disease severity in familial adenomatous polyposis: Systematic review.

Background and study aims There is limited consensus on the optimal method for measuring disease severity in familial adenomatous polyposis (FAP). We aimed to systematically review the operating properties of existing endoscopic severity indices for FAP. Methods We searched MEDLINE, EMBASE, and the Cochrane Library from inception to February 2023 to identify randomized controlled trials (RCTs) that utilized endoscopic outcomes or studies that evaluated the operating properties of endoscopic disease severity indices in FAP. Results A total of 134 studies were included. We evaluated scoring indices and component items of scoring indices, such as polyp count, polyp size, and histology. Partial validation was observed for polyp count and size. The most commonly reported scoring index was the Spigelman classification system, which was used for assessing the severity of duodenal involvement. A single study reported almost perfect interobserver and intra-observer agreement for this system. The InSIGHT polyposis staging system, which was used for assessing colorectal polyp burden, has been partially validated. It showed substantial interobserver reliability; however, the intra-observer reliability was not assessed. Novel criteria for high-risk gastric polyps have been developed and assessed for interobserver reliability. However, these criteria showed a poor level of agreement. Other scoring indices assessing the anal transition zone, duodenal, and colorectal polyps have not undergone validation. Conclusions There are no fully validated endoscopic disease severity indices for FAP. Development and validation of a reliable and responsive endoscopic disease severity instrument will be informative for clinical care and RCTs of pharmacological therapies for FAP.