Background: The use of fixed orthodontic appliances can affect oral health as it may hinder proper tooth brushing and limit areas of the teeth with low saliva flow, increasing the likelihood of bacterial attachment and biofilm (plaque) formation. The use of chlorhexidine (CHX) mouthwash is one way to reduce plaque accumulation in the oral cavity. Objective: The aim of this article is to assess the impact and mechanism of CHX mouthwash on the oral health of users of fixed orthodontic appliances, particularly in terms of plaque accumulation. Results: Ten articles met the criteria and were used as secondary data in this article. The research types varied from randomized controlled trials (RCTs), cross-sectional studies, to literature and systematic reviews. Users of fixed orthodontic appliances are at high risk for plaque formation, even with regular tooth brushing. CHX mouthwash can significantly reduce the number of bacterial colonies responsible for plaque formation in orthodontic users. Conclusion: CHX mouthwash is considered an effective material to reduce plaque in users of fixed orthodontic appliances. However, the dosage of CHX should be carefully considered to minimize side effects.
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