Prolonged Operation Research Articles

Research on the Stability of Salt Cavern Hydrogen Storage and Natural Gas Storage under Long-Term Storage Conditions

The stability of salt cavern storage during prolonged operation is a crucial indicator of its safety. This study focuses on an operational underground gas storage facility, conducting comparative numerical simulations for the storage of natural gas and hydrogen. We investigated the evolution of stability for natural gas and hydrogen storage under long-term storage conditions. The main conclusions are as follows: (1) A new equation for stress equilibrium and constitutive relations are derived. (2) At the same storage pressure, the effective stress at the same position in the interlayer is greater for hydrogen storage compared to natural gas storage, signifying a higher level of danger. (3) At the same storage pressure, the displacement at the cavity top for hydrogen storage is greater than that for natural gas storage. The displacement difference between the two is greatest at 9 MPa, amounting to 0.026 m. (4) Due to hydrogen’s lower dynamic viscosity and higher permeability, the depth and extent of the plastic zones within the interlayers are greater compared to natural gas. When the storage pressure is 15 MPa, the depth of the plastic zone within the interlayer can be up to 2.1 m greater than when storing natural gas, occurring in the third interlayer from the top. These research findings may serve as a valuable reference for determining the operational parameters of on-site salt cavern hydrogen storage facilities.

Evolution of Lubrication Characteristics of Double-Nut Ball Screws Based on an Efficient Surface Roughness Modeling Method

Abstract Accurate prediction of lubrication characteristics, specifically film thickness and pressure distribution, is pivotal for ensuring optimal performance in ball screws. Despite its significance, there is a notable dearth of studies investigating the evolution of lubrication characteristics resulting from the changing surface roughness over prolonged operation of ball screws. Furthermore, obtaining the surface roughness of ball screws poses a challenge due to the limited loading capacity of measurement instruments. Traditional methods involving cutting the screw for surface roughness measurement are impractical for continuous monitoring during extended operation. To address this issue, the present study introduces an efficient approach to model the surface roughness of the raceway in double-nut ball screws. A profilometer is employed to measure profile roughness along two directions (parallel and perpendicular to the rolling direction) without the need to cut the screw raceway. The 2D power spectral densities and height probability densities of profile roughness are calculated to model the surface roughness, and the synthesized data are utilized to solve the Reynolds equation. The simulation method is validated through friction torque tests, demonstrating a calculation accuracy exceeding 92%. The study further explores the evolution of film thickness and pressure distribution in double-nut ball screws during running-in and steady wear stages, revealing severe asperity contact in the two nuts. Additionally, variations in load ratio, friction coefficient, and film thickness ratio (λ) are investigated. Considering the load ratio and λ of the slave nut, it can be inferred that boundary lubrication persists in the two nuts throughout the operation.

Comparative study of robotic-assisted single-incision-plus-one port and single-incision laparoscopic choledochal cyst excision.

To compare the efficacy of robotic-assisted single-incision-plus-one-port laparoscopic choledochal cyst excision (R-SILC + 1) and single-incision laparoscopic choledochal cyst (SILC) in treating pediatric choledochal cyst (CDC). We retrospectively analyzed the clinical data of patients diagnosed with CDC in our hospital from June 2021 to October 2023. Among them, patients underwent either R-SILC + 1 or SILC procedures. Demographic parameters, operative details, and postoperative outcomes were studied. A total of forty-nine patients were included, with 23 children undergoing R-SILC + 1 and 26 children undergoing SILC. There were no statistically significant differences in demographic data, postoperative pain scores, and postoperative complication rates between the two groups (all p > 0.05). Compared with the SILC group, the R-SILC + 1 group demonstrated less intraoperative bleeding volume (10.4 ± 3.6 vs. 15.0 ± 3.6 ml, p < 0.05), a shorter indwelling time of the abdominal drainage tube [5(5,6) vs. 7(5.8,8.3) d, p < 0.05], a shorter postoperative fasting time [4(3,4) vs. 6(5,7) d, p < 0.05], and a shorter postoperative discharge time [6(6,7) vs. 8(6,11) d, p < 0.05]. However, the R-SILC + 1 group had a longer operation time [388(295,415) vs. 341(255.8,375.2) min, p < 0.05] and higher hospitalization cost (7.9 ± 0.4 vs. 3.2 ± 0.3 ten thousand, p < 0.05). Compared with the SILC group, the R-SILC + 1 group demonstrated clear advantages in treating pediatric CDC, but it is associated with a prolonged learning curve and operation time, and high costs. With improvements in physician experience and technological advancements, its potential will be further unleashed.

Optimization of the Camellia oleifera Fruit Harvester Engine Compartment Heat Dissipation Based on Temperature Experiments and Airflow Field Simulation

The Camellia oleifera fruit harvester, a specialized agricultural device, is engineered for efficient operation within the densely planted C. oleifera groves of China’s undulating terrains. Its design features a notably small footprint to navigate the constrained spaces between trees. With the enhancement of the functionality and power of the harvester, the engine compartment becomes even more congested. This, while beneficial for performance, complicates heat dissipation and reduces harvesting efficiency. In this study, experiments were initially conducted to collect temperature data from the main heat-generating components and parts susceptible to high temperatures within the harvester’s engine compartment. Subsequently, a 3D model was developed for numerical simulations, leading to the proposal of optimization schemes for the engine compartment’s structure and the validation of these schemes’ feasibility. A comparison of the experimental data, both before and after optimization, revealed a significant reduction in the surface temperatures of components within the engine compartment following optimization. As a result, the heat dissipation of the engine compartment has been greatly optimized. The harvester has demonstrated prolonged normal operation, enhancing the reliability and economy of the harvester.

Capillary container array structures for efficient, energy-saving, and sustainable evaporative cooling and humidification

Evaporative cooling is a widely employed method for air conditioning and heat dissipation, utilizing the phase transition of water to achieve simultaneous cooling and humidification. It relies on high-surface-area solid materials to enhance air-liquid contact upon wetting. However, these water-absorbing materials have drawbacks such as increased air resistance, degradation of water quality, and limited water retention capabilities. This study introduces a novel structure called the capillary container array (CCA) for effective humidification and cooling. The CCA structure overcomes the limitations of traditional methods by incorporating interconnected capillary containers with adjustable spacing and utilizing capillary forces to capture liquid droplets while minimizing the solid component. Compared to commercial paper-based wet curtains, the CCA structure offers significant advantages including strong water retention capabilities, high humidification performance, low air resistance and high pollution resistance. It increases water capacity by 6 times, humidification capacity by 8 %, and temperature drop by 2.2 °C. Moreover, it exhibits a 5-fold longer in water retention duration, a 30 % reduction in air pressure drop and a 3-fold increase in the performance coefficient, and maintains excellent water quality (<1 NTU) over prolonged operation. These advancements make the CCA structure highly promising for various applications in agriculture, industry and environmental conservation.

Are Preoperative CT Findings Useful in Predicting the Duration of Laparoscopic Appendectomy in Pediatric Patients? A Single Center Study.

Background/Objectives: Preoperative computed tomography (CT) imaging plays a vital role in accurately diagnosing acute appendicitis and assessing the severity of the condition, as well as the complexity of the surgical procedure. CT imaging provides detailed information on the anatomical and pathological aspects of appendicitis, allowing surgeons to anticipate technical challenges and select the most appropriate surgical approach. This retrospective study aimed to investigate the correlation between preoperative CT findings and the duration of laparoscopic appendectomy (LA) in pediatric patients. Methods: This retrospective study included 104 pediatric patients diagnosed with acute appendicitis via contrast-enhanced CT who subsequently underwent laparoscopic appendectomy (LA) between November 2021 and February 2024. CT images were meticulously reviewed by two experienced radiologists blinded to the clinical and surgical outcomes. The severity of appendicitis was evaluated using a five-point scale based on the presence of periappendiceal fat, fluid, extraluminal air, and abscesses. Results: The average operation time was 51.1 ± 21.6 min. Correlation analysis revealed significant positive associations between operation time and neutrophil count (p = 0.014), C-reactive protein levels (p = 0.002), symptom-to-operation time (p = 0.004), and appendix diameter (p = 0.017). The total CT score also showed a significant correlation with operation time (p < 0.001). Multiple regression analysis demonstrated that a symptom duration of more than 2 days (p = 0.047), time from CT to surgery (p = 0.039), and the presence of a periappendiceal abscess (p = 0.005) were independent predictors of prolonged operation time. In the perforated appendicitis group, the presence of a periappendiceal abscess on CT was significantly associated with prolonged operation time (p = 0.020). In the non-perforated group, the presence of periappendiceal fluid was significantly related to longer operation times (p = 0.026). Conclusions: In our study, preoperative CT findings, particularly the presence of a periappendiceal abscess, were significantly associated with prolonged operation times in pediatric patients undergoing laparoscopic appendectomy. Elevated CRP levels, the time between CT imaging and surgery, and a symptom duration of more than 2 days were also found to significantly impact the procedure's duration.

Cost Analysis of Pelvic Exenteration Surgery for Advanced Pelvic Malignancy.

Pelvic exenteration (PE) is a radical procedure involving multi-visceral resection for locally advanced pelvic malignancies. Such radical surgery is associated with prolonged operating theater time and hospital stay, as well as a substantial risk of postoperative complications, and therefore significant financial cost. This study aimed to comprehensively detail the inpatient cost of PE at a specialist center in the Australian public sector. A retrospective costing review of consecutive PE operations at Royal Prince Alfred Hospital in Sydney between March 2014 and June 2022 was performed. Clinical data were extracted from a prospectively maintained database, and in-hospital costing data were provided by the hospital Performance Unit. All statistical analyses were performed using SPSS. Pelvic exenteration was performed for 461 patients, of whom 283 (61 %) had primary or recurrent rectal cancer, 160 (35 %) had primary or recurrent non-rectal cancer, and 18 (4 %) had a benign indication. The median admission cost was $108,259.4 ($86,620.8-$144,429.3) (Australian dollars [AUD]), with the highest costs for staffing followed by the operating room. Overall, admission costs were higher for complete PE (p < 0.001), PE combined with cytoreductive surgery (CRS) (p < 0.001), and older patients (p = 0.006). The total admission cost for patients undergoing PE reflects the complexity of the procedure and the multidisciplinary requirement. Patients of advanced age undergoing complete PE and PE combined with CRS incurred greater costs, but the requirement of a sacrectomy, vertical rectus abdominal flap reconstruction, major nerve or vascular excision, or repair were not associated with higher overall cost in the multivariate analysis.

Directional‐Thermal‐Conductive Phase Change Composites Enabling Efficient and Durable Water‐Electricity Co‐Generation Beyond Daytime

AbstractSolar‐driven water‐electricity co‐generation (WEC) emerges as a viable solution to address global freshwater and energy scarcity. Phase change materials (PCMs)‐based WEC systems have been proposed to solve intermittent solar radiation issues. Nevertheless, WEC performances decline significantly leading to limited operating durations in dark. The study proposes a new concept of directional‐thermal‐conductive PCMs to address above challenges. By precisely regulating hydrophilicity/hydrophobicity distribution of Cu substrates, the structural disorder of boron nitride‐based PCMs is effectively tuned to achieve directional thermal transport. These directional‐thermal‐conductive PCMs exhibit a high phase transition enthalpy of 250.4 J g−1 and a large thermal‐conductivity anisotropy index of 3.24, which improves heat exchange between PCMs and photothermal/thermoelectric, and minimizes transverse heat dissipation simultaneously. Consequently, the directional‐thermal‐conductive PCMs‐based WEC achieves evaporation rates of 2.51 kg m−2 h−1 with power outputs of 1759.7 mW m−2 at 1 sun, among the best performance reported in the state‐of‐the‐art studies. More impressively, its evaporation rate still reaches 0.93 kg m−2 h−1 with a superior power output of 411.0 mW m−2 and a prolonged operation time of 90 minutes in nighttime, significantly surpassing previously‐reported devices with nondirectional‐thermal‐conductive designs. Finally, an omniphobic PVDF membrane is demonstrated that can improve the anti‐fouling performance of WEC systems for prolonged lifespan.

Self-powered wearable remote control system based on self-adhesive, self-healing, and tough hydrogels

The advent of the fifth-generation mobile communication network era induces a great potential for the design and development of self-powered wearable electronic devices. Hydrogels, as a typical material for flexible electrodes, have been widely employed in self-powered wearable electronic devices. However, the hydrogel-based triboelectric nanogenerator (H-TENG) is usually compromised by the challenges in data collection, operational stability, and manufacturability due to the unstable combination between the friction layer and the electrode layer, the occurrence of hydrogel damage during prolonged operation, and also the difficulty of machining sticky hydrogel electrodes. In the present study, a composite hydrogel composed of acrylamide, crotonyl alcohol, and 4-carboxyphenylboronic acid was synthesized via ultraviolet crosslinking, which was specially developed for H-TENG and wearable wireless remote control interface, featuring with excellent stretchability and mechanical strength as well as self-healing and self-adhesive properties. The open-circuit voltage of the H-TENG prepared with the hydrogel reached up to 165 V, and the output voltage remained almost unchanged following 10,000 cycles of compression test. Additionally, a wearable wireless remote control system was designed that could accurately control the multiple appliances and adjust different working modes using the H-TENG. Consequently, the development of the H-TENG and wearable wireless remote control system has the potential to provide a new methodology for the application of next-generation wearable devices in various areas, such as smart homes, as a representative example.

Methods and Strategies of Microsurgery Combined with Ilizarov Technique in the Treatment of Amputation of Limbs in Renji Hospital: A Report of 51 Cases.

Severe limb amputation trauma often results in bone and soft tissue defects after debridement. Traditional replantation aims to save the limb by shortening the ischemic period and using autologous transplantation for repair, but it can lead to surgical trauma, donor site damage, and prolonged operation time. Due to contusion, pollution, and complex injury, there is no unified standard for replantation and fixation. Improper operation can easily lead to complications such as bone infection, nonunion, bone defect, and joint stiffness. This study introduces the Ilizarov technique into microsurgery to improve limb lengthening after reconstruction and standardizes the steps of replantation fixation for complex limb avulsion injuries, with a focus on clinical efficacy. A retrospective analysis was performed on 51 patients with complex limb amputation who were treated in Zhengzhou Renji Hospital from June 2009 to March 2021. On the basis of microsurgical limb replantation, Ilizarov technology was introduced to innovate the internal and external combined stepwise fixation method for replantation. Patients' gender, age, height, weight, BMI, and other general information were collected. X-ray films were reviewed regularly to observe the surgical healing of fracture, that is, the degree of limb shortening. The lengthening time, carrying time after lengthening, follow-up time, Dahl classification, Paley fracture healing classification, and Chen Zhongwei's replantation function score were used to evaluate the recovery of the affected limb. A total of 51 patients were included in this group, including 36 male patients and 15 female patients. All the amputated wounds were single limb amputation. In this group of patients, the hind limbs were shortened by 2-12.5 cm (5.32 ± 2.24) after replantation. A total of 44 patients whose hind limbs were shortened by more than 2.5 cm were treated with two-stage Ilizarov lengthening for 1.5-5.5 months (3.19 ± 1.03). The carrying time was 3-7.5 months (4.25 ± 0.94), and the follow-up time was 1-7.8 years (3.76 ± 1.69). Among the 49 survived patients, the Dahl grade of external fixation was less than Grade 2 in 89.8%. The excellent and good rate of Paley fracture healing classification was 89.8%. The excellent and good rate of Chen Zhongwei's limb replantation function classification was 79.6%. Microsurgery combined with Ilizarov technique in the treatment of limb amputation injury, limb salvage reconstruction with internal and external combined step-by-step combined fixation, and one-stage shortening and two-stage limb lengthening can reduce the occurrence of osteomyelitis, bone defect and nonunion, expand the indications of limb replantation, improve the success rate of limb replantation, with satisfactory results, and facilitate the promotion of clinical techniques.

Fast algebraic multigrid for block-structured dense systems arising from nonlocal diffusion problems

Algebraic multigrid (AMG) is one of the most efficient iterative methods for solving large structured systems of equations. However, how to build/check restriction and prolongation operators in practical AMG methods for nonsymmetric structured systems is still an interesting open question in its full generality. The present paper deals with the block-structured dense and Toeplitz-like-plus-cross systems, including nonsymmetric indefinite and symmetric positive definite (SPD) ones, arising from nonlocal diffusion problems. The simple (traditional) restriction operator and prolongation operator are employed in order to handle such block-structured dense and Toeplitz-like-plus-cross systems, which are convenient and efficient when employing a fast AMG. We provide a detailed proof of the two-grid convergence of the method for the considered SPD structures. The numerical experiments are performed in order to verify the convergence with a computational cost of only O(NlogN)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\\mathscr {O}(N \ ext{ log } N)$$\\end{document} arithmetic operations, by exploiting the fast Fourier transform, where N is the number of the grid points. To the best of our knowledge, this is the first contribution regarding Toeplitz-like-plus-cross linear systems solved by means of a fast AMG.

The effect of intraoperative fluoroscopy on acetabular component positioning and patient anatomy restoration during total hip arthroplasty: A systematic review and meta-analysis.

In total hip arthroplasty (THA), the positioning of components holds critical importance for factors such as joint stability, polyethylene liner wear, and range of motion. This meta-analysis aimed to compare the effects of intraoperative fluoroscopy (IF) versus no use of IF on component positioning and the restoration of patient anatomy during THA. We conducted our systematic review following the recommendations outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. The literature search was performed from the inception of medical databases up to August 2023. PubMed, Embase, Web of Science, Cochrane Controlled Trials Register, Cochrane Library, Highwire, Wanfang, China National Knowledge Infrastructure (CNKI), China Biology Medicine Disc (CBM), and China Science and Technology Journal (CSTD) databases were systematically searched to identify relevant studies comparing IF versus no IF during primary THA. Thirteen studies involving 2195 patients (2207 hips) were incorporated in the Analysis. No statistically significant differences were observed between the groups in terms of acetabular cup inclination angle (ACIA, P = .9), ACIA within the safe zone rate (P = .87), acetabular cup anteversion angle (ACAA, P = .42), ACAA within the safe zone rate (P = .35), combined safe zone rate (P = .30), limb length difference (LLD, P = .13), dislocation rate (P = .76), and infection rate (P = .97). In comparison to the no fluoroscopy group, the IF group exhibited prolonged operation time (P < .00001) and reduced femoral component offset difference (FCOD, P = .03). IF did not demonstrate improvements in acetabular cup placement, limb length difference, or dislocation occurrence. Nonetheless, IF showed a significant enhancement in restoring femoral offset. It is noteworthy that surgeons operating in facilities with lower patient volumes may observe more pronounced benefits from IF.

Solvent Minimized Synthesis of Amides by Reactive Extrusion

AbstractHerein, we report on the translation of a small scale ball‐milled amidation protocol into a large scale continuous reactive extrusion process. Critical components to the successful translation were: a) understanding how the different operating parameters of a twin‐screw extruder should be harnessed to control prolonged continuous operation, and b) consideration of the physical form of the input materials. The amidation reaction is applied to 36 amides spanning a variety of physical form combinations (liquid‐liquid, solid–liquid and solid‐solid). Following this learning process, we have developed an understanding for the translation of each physical form combination and demonstrated a 7‐hour reactive extrusion process for the synthesis of an amide on 500 gram scale (1.3 mols of product).

Solvent Minimized Synthesis of Amides by Reactive Extrusion.

Herein, we report on the translation of a small scale ball-milled amidation protocol into a large scale continuous reactive extrusion process. Critical components to the successful translation were: a) understanding how the different operating parameters of a twin-screw extruder should be harnessed to control prolonged continuous operation, and b) consideration of the physical form of the input materials. The amidation reaction is applied to 36 amides spanning a variety of physical form combinations (liquid-liquid, solid-liquid and solid-solid). Following this learning process, we have developed an understanding for the translation of each physical form combination and demonstrated a 7-hour reactive extrusion process for the synthesis of an amide on 500 gram scale (1.3 mols of product).

Mesenchymal stem cells arouse myocardial NAD+ metabolism to alleviate microgravity-induced cardiac dysfunction

After prolonged space operations, astronauts showed maladaptive atrophy within mostly left-ventricular myocardium, resulting in cardiac dysfunction. However, the mechanism of cardiac dysfunction under microgravity conditions is unclear, and the relevant prevention and treatment measures also need to be explored. Through simulating the microgravity environment with a tail suspension (TS) model, we found that long-term exposure to microgravity promotes aging of mouse hearts, which is closely related to cardiac dysfunction. The intravenous administration of adipose-derived mesenchymal stem cells (ADSCs) emerged preventive and therapeutic effect against myocardial senescence and the decline in cardiac function. Plasma metabolomics analysis suggests the loss of NAD+ in TS mice and motivated myocardial NAD + metabolism and utilization in ADSCs-treated mice, likely accounting for ADSCs' function. Oral administration of nicotinamide mononucleotide (NMN, a NAD + precursor) showed similar therapeutic effect to ADSCs treatment. Collectively, these data implicate the effect of ADSCs in microgravity-induced cardiac dysfunction and provide new therapeutic ideas for aging-related maladaptive cardiac remodeling.

Thermal enhancement of targeted cooling thermosyphon array applied to the embankment–bridge transition section of the Qinghai–Tibet railway in warm permafrost

Permafrost degradation in the embankment–bridge transition section (EBTS) along the Qinghai–Tibet Railway has led to extensive damage to bridge structures, posing a serious threat to railway safety. With the ongoing global warming, reinforcing the affected EBTS to ensure long-term stability remains a pressing challenge. To address this issue, this study proposes a targeted cooling thermosyphon array (TCTA) approach utilising variable inclination evaporator (VIE) thermosyphons. The effectiveness of the VIE thermosyphon was evaluated through an in-situ test. Meanwhile, a three-dimensional numerical model was employed to analyse the overall cooling effect, long-term performance and thermal enhancement provided by the TCTA approach. The findings indicated that the VIE thermosyphon exhibited excellent cooling performance and maintained uniform wall temperature, with the lowest wall temperature reaching −15 °C. Within one year of implementation, a cold core of −2 °C formed at the centre of the foundation, and the permafrost table was uplifted by approximately 3 m, showcasing its potential to rapidly enhance the thermal stability of in-service EBTS in permafrost. With prolonged operation, the cold accumulative effect of this approach gradually becomes apparent, and the range of the low-temperature cores expands. This method effectively reinforces the thermal stability of in-service EBTS and is well-suited for future railway construction in warm permafrost amidst the challenges of climate change.

A sensitive wavelength-enhanced reconstruction algorithm for track quality assessment based on measured data and vehicle dynamics

High-speed railways are extensively utilized worldwide. However, with prolonged operation, track irregularities increasingly pose significant challenges, adversely affecting the safety and stability of train operations. This paper proposes a sensitive wavelength-enhanced reconstruction algorithm based on the cmplete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) method to address this issue. This method evaluates the influence of reconstructed track irregularities on vehicle dynamic response, considering sensitive wavelengths and amplification factors. The algorithm effectively enhances these sensitive wavelengths while maintaining the integrity of the input signal, utilizing measured track irregularities. After applying the algorithm, the maximum vertical body acceleration rises by 206.09%. The study validates a coupled train model and analyzes the mapping relationship between single-wave irregularities and vertical body acceleration. Compared to random irregularities, the maximum vertical acceleration can amplify up to 122.80% under various operating conditions. The periodic sensitive wavelengths of track irregularities significantly impact the train’s dynamic response.

315. SHORT-TERM RESULTS OF ROBOT-ASSISTED SURGERY FOR ESOPHAGEAL CANCER IN JAPAN 5 YEARS AFTER INSURANCE COVERAGE

Abstract Background In Japan, robot-assisted surgery (RAMIE) for esophageal cancer surgery was covered by insurance in 2018, and its introduction has been rapidly progressing since then. In our department, RAMIE has been introduced and performed in 250 cases so far. In the process, we have improved the short-term results by introducing the standardization and NIM (neuromonitoring) according to the characteristics of RAMIE. In addition, we have recently expanded the use of RAMIE in advanced cancer patients due to its usefulness in stable operation. In this meeting, we will review the short- and mid-term results and discuss current issues. Methods We analyzed the short-term results of all 213 RAMIE cases performed at our department, and compared them with the short-term results of 51 post-standardization (late) MIE cases previously reported. The mid-term results to date were also reviewed. Results A total of 213 patients were included. 211, 222 mins thoracic operation time. 235, 190 ml blood loss in comparison to MIE (vs. RAMIE). Postoperative outcomes were similar: overall complications (&amp;gt;Grade II) were 49, 54.9%, respiratory complications were 19.6, 23.9%, and recurrent nerve palsy was 15.7, 17.4%. Risk analysis demonstrated that paralysis in RAMIE was significantly related to prolonged thoracic operation time (p=0.021) and NIM (Odds=0.38, p=0.0447). In comparison between patients with early-stage and advanced cancer, pneumonia and anastomotic complications were not different. Prognosis was 81.7/64.2% (UICC 8th) for 3-year survival in cStage II/III patients. Conclusion RAMIE was considered to be highly useful for short-term and medium-term outcomes at this time.

Possibilities for Improving Algorithms for Combat Use of Aircraft Using Unguided Weapons

Combat actions in recent local conflicts make us consider and re-evaluate some of the concepts concerning the development of combat aviation. As it turns out, conducting combat operations at high intensity for a long period of time using all components of the armed forces shows that the use of high-tech aircraft is extremely expensive and requires a large period of time to bring them back to full operational readiness when damage has been inflicted on them during hostilities. This is evidenced by the limited use of 5th generation aircraft in local conflicts. They are mainly used at long distances and with a tangible technological superiority over the enemy. Also, the sustained use of high precision guided weapons proves to be extremely expensive. All this makes us think and apply a creative approach to finding a solution to these problems. One of these approaches is through the improvement or rather the modernization of existing combat platforms through the implementation of advanced mathematical models and algorithms for combat use, which will increase the accuracy and efficiency of the use of unguided weapons, which are significantly cheaper compared to using guided ones. As the accuracy of using unguided weapons increases, it approaches that of guided ones. This is very important in the conduct of prolonged intensive combat operations in the conditions of limited resources. On the other hand, the use of advanced algorithms for combat use will simplify and facilitate the pilot's work with the controls of the aviation armament during the execution of combat tasks.A general mathematical model and a general algorithm for the combat use of aircraft weapons are proposed. A general mathematical model was developed for solving the ballistic task for large groups of guided and unguided weapons, which is a component of the general algorithm for combat use.

Enhancing collaboration of anammox with heterotrophic microbes mediated selectively by iron of different valences: Activities balance, metabolic mechanism, and functional genes regulation

The partial denitrification/anammox (PD/A) process is receiving increasing attention due to its cost-effectiveness advantages. However, effective strategies to alleviate organic matter inhibition and promote anammox activity have been proven to be a big challenge. This study investigated the effects of three types of iron (nano zero-valent iron (nZVI), Fe(II), and Fe(III)) on the PD/A process. It is worth noting that nZVI of 5–50 mg/L and Fe(III) of 5–120 mg/L promoted both PD and anammox activity. Long-term intermittent addition of nZVI (50 mg/L) resulted in a nitrogen removal efficiency of 98.2% in the mixotrophic PD/A system driven by iron and organic matter. The contribution of anammox for nitrogen removal reached as high as 93.8%. The organic carbon demand decreased due to the external electron donor provided by nZVI for PD. Multiple Fe–N metabolic pathways, primarily involving ammonia oxidation by Fe(III) and nitrate reduction by nZVI, play a crucial role in facilitating nitrogen transformation. Conversely, the direct addition of 30–120 mg/L Fe (II) resulted in a significant decrease in pH to below 5.0 and severe inhibition of PD and anammox activity. Following prolonged operation in the presence of nZVI, it was demonstrated that there is an enhancing effect on robust nitrite production for anammox. This was accompanied by a remarkable up-regulation of genes encoding nitrate reductase and iron-transporting proteins dominated by Thauera. Overall, this study has provided an efficient approach for advanced nitrogen removal through organic- and iron-driven anammox processes.