193 nm immersion lithography optical projection systems using conventional UV optical materials and water as the immersion fluid, with planar lens/fluid interfaces, have a practical numerical aperture (NA) limit near 1.3. Higher-index resists and immersion fluids are being developed, but the bottleneck for pushing the NA further is the relatively small refractive index of the final lens element material. In this paper we consider the possibility of using novel high-index materials in the last lens element to get around this bottleneck and to push the NA limit to at least 1.5, while containing the lens system size and complexity. We discuss four classes of high-index (n>1.8), wide-band-gap, oxide-based materials that have the potential for being fabricated with optical properties appropriate for lithography optics: group-II oxides, magnesium-aluminum-spinel-related materials, ceramic forms of spinel, and aluminum garnets. We present measurements of the optical properties of these materials, including intrinsic birefringence, and we assess their prospects.