Abstract Ethyl lactate is widely used as a solvent for several industries and usually produced by esterifaciton of lactic acid with ethanol. In order to lower its production cost, attempt to synthesis this ester directly from lactate salt produced by bacterial fermentation was made. In this work, reactive distillation process for small-scale synthesis of ethyl lactate from esterification of fermentation-derived magnesium lactate with ethanol was designed and simulated using Aspen Plus simulator equipped with RADFRAC module. Non-ideality of the reaction components was represented by UNIQUAC property model. Specification and optimum conditions of reactive distillation and fractional distillation units in the proposed process scheme were obtained. Under the process scheme and operating conditions proposed in this work, approximately 96.13% of lactic acid was converted and 95.76% yield of ethyl lactate was achieved.
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