Process In Order Research Articles

INOVASI E-COMMERCE UNTUK OPTIMALISASI PROSES KONSUMEN, PRODUKSI, DAN PEMASARAN BAGI PELAKU UMKM

E-commerce technology enables efficient online transactions, providing customers with a convenient and efficient purchasing experience. In terms of production, e-commerce information systems can be integrated with production management, enabling monitoring of the production process, optimizing production efficiency and reducing the risk of stock shortages. E-commerce technology also opens up opportunities for more sophisticated marketing strategies, as MSMEs can utilize consumer data analysis, increasing customer appeal and ordering and sales. E-commerce technology facilitates direct interaction between consumers, fostering closer relationships and improving customer experience. The development of e-commerce technology has significantly increased the effectiveness and efficiency of MSMEs specifically in the fried chicken sector, enabling them to compete in the digital business era. The purpose of this study is to develop an E-Commerce information system in the "Maju Makmur" Kalasan fried chicken industry center that manages MSMEs fried chicken. The research method is a prototype model. This model starts from data collection, system design and testing. The stages of the prototyping development model consist of: communication, rapid planning, rapid modeling, construction, and delivery. The results of this study are a web-based system to optimize consumer, production, and marketing processes in order to increase operational efficiency and market access through an online platform.

The influence of interleukin-4 on transendothelial transport of low-density lipoproteins

BACKGROUND: Cytokines are important participants in the atherosclerotic process. The product of T-helpers and mast cells, interleukin-4, causes activation of endothelial cells and induces polarization of macrophages into anti-inflammatory M2 phenotype. AIM: The aim was to study the influence of interleukin-4 on the activation of transendothelial transport of low-density lipoproteins. MATERIALS AND METHODS: Low-density lipoproteins transendothelial transport was evaluated in a two-chamber model on a monolayer of human endothelial cell line EA.hy926. For that, 200 mkg/ml of low-density lipoproteins, and 1, or 10, or 100 ng/ml of interleukin-4, or 10, or 50 ng/ml of interleukin-6, or 50 ng/ml of tumor necrosis factor, or 10 ng/ml of interleukin-4 and 50 ng/ml of tumor necrosis factor, or a phosphate buffer saline were added to the cells on 24 h. The integrity of endothelial monolayer was controlled by the passage through 1 mkg/ml of fluorescein Na. The levels of mRNA and proteins in the cells were determined by reverse transcription polymerase chain reaction and Western blotting, the activity of matrix metalloproteinases-1, -2 and -9 in the culture medium — by zymography, interleukin-6 and -8 concentrations — by enzyme-linked immunosorbent assay. RESULTS: Interleukin-4 had no effect on the passage of low-density lipoproteins through the monolayer of endothelial cells in basal and tumor necrosis factor stimulation conditions. At the same time, interleukin-4 suppressed interleukin-8 secretion by cells and increased their production of interleukin-6. The latter also did not cause the changes in the permeability of endothelial monolayer. In addition, interleukin-4 did not affect the expression of CAV, SCARB1, ACVRL1 genes, encoding proteins involved in low-density lipoproteins transendothelial transport. An addition of interleukin-4 or -6 to the cells did not change the activity of the matrix metalloproteinases. CONCLUSIONS: Interleukin-4 does not affect the transendothelial transport of low-density lipoproteins, while modulating the production of other cytokines by endothelial cells. In the future, it is necessary to establish the effect of a wider range of cytokines produced by intimal cells on low-density lipoproteins transendothelial transport, as well as to clarify the molecular mechanisms of influence of tumor necrosis factor on this process in order to identify new targets for atherosclerosis therapy.

Impact Evaluation Adoption Towards Coastal Communities with Ongoing East Coast Rail Link (ECRL) in Terengganu

Objective: This article focuses on ongoing ECRL development challenges in Terengganu, Malaysia, by adapting the All-Party Parliamentary Group Malaysia on Sustainable Development Goals (APPGM-SDG) impact evaluation framework, which can serve as a tool for policy intervention in reducing inequality and promoting partnership. Theoretical Framework: The role of the state theory, as applied to explain the initiative launched through state coordination, requires a multistakeholder approach or structuration process in order to assess the impact on the beneficiary's sustainability. Method: The methodology adopted for this research has included in-depth interviews, observations, and site-visit approaches with local people and authoritative informants, and is heavily supported by desk research. Results and Discussion: The result shows that local coastal communities of several towns in Setiu, Terengganu, are positively accepting of this ECRL development. Nevertheless, collaboration and further information are also needed to make themselves compatible with socioeconomic changes. Research Implications: The critical APPGM-SDG mechanism, based on its success story in terms prior impact evaluation, should be embraced in assessing ongoing ECRL and its development through government-to-government partnerships. Originality/Value: This study led to the three imperatives recommendations on the academic context of the development corpus, advocacy, and policy moral deliverables.

Enhancing Personalized Learning Through Process Mining

AbstractTechnology-mediated learning offers new possibilities for individualizing learning processes in order to discover, monitor, and enhance students’ learning activities. However, leveraging such possibilities automatically and at scale with novel technologies raises questions about the design and the analysis of digital learning processes. Process mining hereby becomes a relevant tool to leverage these theorized opportunities. The paper classifies recent literature on individualizing technology-mediated learning and educational process mining into four major concepts (purpose, user, data, and analysis). By clustering and empirically evaluating the use of learner data in expert interviews, the study presents three design patterns for discovering, monitoring, and enhancing students’ learning activities by means of process mining. The paper explains the characteristics of these patterns, analyzes opportunities for digital learning processes, and illustrates the potential value the patterns can create for relevant educational stakeholders. Information systems researchers can use the taxonomy to develop theoretical models to study the effectiveness of process mining and thus enhance the individualization of learning processes. The patterns, in combination with the taxonomy for designing and analyzing digital learning processes, serve as a personal guide to studying, designing, and evaluating the individualization of digital learning at scale.

A novel cross fusion model with fine-grained detail reconstruction for remote sensing image pan-sharpening

ABSTRACT Pan-sharpening aims to obtain high resolution multispectral (HRMS) images by integrating the information in the panchromatic and multispectral images. Existing pan-sharpening methods have demonstrated impressive sharpening performance. However, these methods inherently overlook the complementary characteristics and interaction between diverse source images, resulting in sharpened outcomes accompanied by distortion. To solve the above problems, we construct a novel cross fusion model with fine-grained detail reconstruction from the perspective of frequency-domain. The motivation of the model is twofold: (1) to reconstruct spatial detail representations from diverse source images, laying the foundation for the generation of fine details in the subsequent fused images; and (2) to enhance the interaction between diverse source features during the fusion process in order to attain high-fidelity fusion outcomes. Based on the theoretical model, we develop a frequency-spectral dual domain cross fusion network (CF2N) utilizing the deep learning technique. Consequently, the CF2N consist of two main stages, namely frequency-domain dominated detail reconstruction (FD2R) and frequency-spectral cross fusion (FSCF). Specifically, a more reasonable reconstruction of fine frequency details in HRMS can be achieved by performing adaptive weighted fusion of frequency details in the FD2R stage. Furthermore, the FSCF module, which seamlessly integrates frequency- and spectral-domain details in a highly interactive cross fusion manner. As a result, the CF2N possesses the capability to attain high frequency-spectral fidelity results with excellent interpretability. Extensive experiments show the superior performance of ours over state of the art, while maintaining high efficiency. All implementations of this work will be published at our website.

Integration Approaches in Forensic Portrait Examination

The article reviews some actual issues of the theory and practice of the production of forensic portrait examinations: the tight deadlines of the preliminary investigation, the increased time expenditures to produce forensic video examination, the need for an integrated approach to the training of forensic portrait experts. The author proposes to revise some approaches to the training of forensic experts in the field of forensic portrait examinations. Along with the possibility of a comprehensive forensic examination, taking into consideration current needs of practice, more attention needs to be paid to software application for processing photo and video images processing in order to improve visual perception of the information displayed and to study montage marks and their detectability. All this will contribute to the evolvement of a portrait examiner as a specialist of double competence.

Pectus excavatum or Pectus chiaroscurum in paintings of St. Jerome (17th century)?

Considering the influence of artistic style is a key methodological step in the iconodiagnostic process in order to avoid some pitfalls. The two present artworks, depicting Saint Jerome, attributed respectively to the 17th-century Neapolitan school and to Valentin de Boulogne, French painter of the 17th century, highlight how the interplay of light and shadow can enhance and disguise a possible pectus excvatum.

Physical Distribution Practices and Marketing Performance of Selected Fast Moving Consumer Goods Companies in South-South Region of Nigeria

This study was designed to investigate the influence of physical distribution practices (transportation management, warehousing management, communication and information systems, and order processing) on the marketing performance of selected fast-moving consumer goods (FMCG) companies in the south-south region of Nigeria. The survey research design approach was adopted using a structured questionnaire to collect data from 247 selected FMCG sales representatives involved in the distribution of FMCG products in the south-south region of Nigeria. Stratified random sampling was employed. The data gathered was analysed using percentages and frequency tables. The formulated hypotheses were tested using a multiple regression approach. Findings from the study revealed a strong positive influence between the independent variables (transportation management, warehouse management, communication and information systems, and order processing management) and the dependent variable (marketing performance). The researchers suggest that FMCG companies should prioritise transportation management to facilitate better and more efficient movement of goods and people, thereby improving their marketing performance. Given the limitations of this study, the researchers presented practical implications and directions for future research.

Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling

Protease-containing ABC transporters (PCATs) couple the energy of ATP hydrolysis to the processing and export of diverse cargo proteins across cell membranes to mediate antimicrobial resistance and quorum sensing. Here, we combine biochemical analysis, single particle cryoEM, and DEER spectroscopy in lipid bilayers along with computational analysis to illuminate the structural and energetic underpinnings of coupled cargo protein export. Our integrated investigation uncovers competitive interplay between nucleotides and cargo protein binding that ensures the latter’s orderly processing and subsequent transport. The energetics of cryoEM structures in lipid bilayers are congruent with the inferred mechanism from ATP turnover analysis and reveal a snapshot of a high-energy outward-facing conformation that provides an exit pathway into the lipid bilayer and/or the extracellular side. DEER investigation of the core ABC transporter suggests evolutionary tuning of the energetic landscape to fulfill the function of substrate processing prior to export.

Produktionssteuerungsumgebungen und ihre (technischen) Probleme

Abstract Technological development is leading to the emergence of new decentralized applications, such as decentralized production systems. Production systems require efficient production control for goal-oriented and resource-saving order processing. The environment in which the production control is implemented contributes significantly to its task fulfilment. This paper examines and analyses centralized and decentralized databases as well as edge and cloud computing as environments for production control. It additionally examines the potential of blockchain technology to solve the various problems of the presented production control environment

Methodological model for teaching residents of foreign language professional communication based on an integrated approach

Importance. The widespread use of foreign language education in non-linguistic universities is due to a number of factors that determine the development of professional activity in various industries. Medicine and healthcare are among the key areas of human activity that require regular updating of knowledge and improvement of professional skills of a specialist in the context of scientific and technological progress. Medical professionals are required to keep abreast of the latest achievements of science and technology, to study new methods of diagnosis, treatment and prevention of diseases in order to provide patients with better medical care. Using the example of the COVID-19 pandemic, the world community realized that the emergence of such threats requires rapid response and cooperation between various countries and organizations. Only through the experience of interaction between scientists and medical professionals from different countries, it was possible to jointly normalize the epidemiological situation around the world. The World Health Organization has played a key role in coordinating international efforts to combat coronavirus infection by providing all the necessary information in foreign languages, mainly English and French. In view of this, there is a social demand in the labor market for medical workers who speak English perfectly, and in higher educational institutions there is a demand for language courses from students of residency. The main purpose of the study is to develop a methodological model for teaching residents of foreign language professional communication based on an integrated approach.Research Methods. To achieve the main goal, theoretical and empirical research methods are applied, which make it possible to study and analyze existing theories and concepts on the topic of developing a methodological model for teaching residents of foreign language professional co mmunication based on an integrated approach. Based on the analysis of the academic literature on the research topic, the regularities of the construction of the methodological model, its functions and component composition are revealed. Modeling of the educational process makes it possible to create an effective methodological model for teaching residents of foreign language professional communication based on an integrated approach.Results and Discussion. The conducted research makes it possible to identify the didactic functions of the methodological model: 1) orienting; 2) regulatory; 3) formative; 4) controlling. Based on the identified didactic functions, a methodological model for teaching residents of foreign la nguage professional communication based on an integrated approach is developed, which is structurally presented in the form of five consecutive blocks: 1) prerequisites; 2) goal setting block; 3) content block; 4) operational and activity block; 5) evaluation and performance block.Conclusion. The developed methodological model for teaching residents of foreign language professional communication based on an integrated approach allows creating a simulation of the educational process in order to identify the strengths and weaknesses of the proposed teaching met hodology. The obtained research results are supposed to be used in the methods of foreign language teaching in medical universities in the training of residents.

Enhancing University-based Organic Product Initiatives through Digital Innovation: a Case Study of Dev Bhoomi Uttarakhand University

This study explores the potential of digital innovation to enhance the organic product initiative at Dev Bhoomi Uttarakhand University (DBUU). Through a mixed-methods approach, including interviews and surveys, we identified key challenges in the current workshop-based production model, such as inefficient order management and lengthy fulfillment times. We propose a mobile application, "DBUU Organic," designed to streamline operations, enhance educational value, and facilitate growth. The app integrates inventory management, order processing, and educational components, addressing current inefficiencies while providing students with hands-on experience in sustainable agribusiness. This research contributes to the growing body of knowledge on integrating technology in agricultural education and sustainable food systems, offering a model for other institutions to emulate.

Effects of Mixtures of Emerging Pollutants and Drugs on Modulation of Biomarkers Related to Toxicity, Oxidative Stress, and Cancer.

Background/Objectives: Over time, the scientific community has developed a growing interest in the effects of mixtures of different compounds, for which there is currently no established evidence or knowledge, in relation to certain categories of xenobiotics. It is well known that exposure to pollutants causes oxidative stress, resulting in the overproduction of reactive oxygen species (ROS), which can affect signaling pathways that regulate the cell cycle, apoptosis, energy balance, and cellular metabolism. The aim of this study was to investigate the effects of sub-lethal concentrations of mixtures of emerging pollutants and pharmaceuticals on the modulation of biomarkers related to toxicity, oxidative stress, and cancer. Methods: In this study, the hepatoma cell line HepG2 was exposed to increasing concentrations of polybrominated diphenyl ether 47 (BDE-47), cadmium chloride (CdCl2), and carbamazepine (CBZ), both individually and in mixtures, for 72 h to assess cytotoxicity using the MTT assay. The subsequent step, following the identification of the sub-lethal concentration, was to investigate the effects of exposure at the gene expression level, through the evaluation of molecular markers related to cell cycle and apoptosis (p53), oxidative stress (NRF2), conjugation and detoxification of xenobiotics (CYP2C9 and GST), DNA damage (RAD51 and γH2AFX), and SUMOylation processes (SUMO1 and UBC9) in order to identify any potential alterations in pathways that are normally activated at the cellular level. Results: The results showed that contaminants tend to affect the enzymatic detoxification and antioxidant system, influencing DNA repair defense mechanisms involved in resistance to oxidative stress. The combined effect of the compounds at sub-lethal doses results in a greater activation of these pathways compared to exposure to each compound alone, thereby exacerbating their cytotoxicity. Conclusions: The biomarkers analyzed could contribute to the definition of early warning markers useful for environmental monitoring, while simultaneously providing insight into the toxicity and hazard levels of these substances in the environment and associated health risks.

Pre-specifiable fixed-time control for quadrotor aircraft with output constraints

For the controller design of quadrotor aircraft with six-DOF, a pre-specifiable fixed-time method combined with state constraints is researched in this paper. The 6-DOF aircraft model is divided into position loop and attitude loop through time scale decomposition method for the convenience of decoupling. Adaptive pre-specifiable fixed-time controllers for the position subsystem and attitude subsystem are proposed to ensure the desired trajectory and the desired attitude angle can be reached within a fixed-time which is independent of initial conditions. Meanwhile, the convergence time can be user-assignable in advance. Time-varying state constraints are considered in the controller design process in order to guarantee the safety of the system and prolong the life of actuator. The Barrier Lyapunov function is applied to ensure quadrotor aircraft’s output constraints are not violated. Finally, the effectiveness of the proposed controller is verified by the simulation experiment.

Awareness and Attitudes Towards Open Access Predatory Publications Among the Academic Staff Members of Faculty of Management Studies and Commerce, University of Jaffna, Sri Lanka

The scholarly community is now dealing with a serious issue with predatory journals. It might be difficult for authors to identify predatory publications apart from reputable ones. The purpose of this study is to investigate the academic staff members of the Faculty of Management Studies and Commerce, University of Jaffna, Sri Lanka on awareness of predatory publications and open access. The research methodology used in this study to gauge participants' knowledge of "open access" and "predatory publishing" was a questionnaire survey. Data collection involved the use of a pretested questionnaire. The permanent academic staff members affiliated with the Faculty of Management Studies and Commerce, university of Jaffna comprised the study's population. A link to an online survey was shared with every one of the faculty's fifty-two academic staff members. The response rate of the study was 67.30 %. MS Excel was used for the data analysis to describe the data in frequencies, percentages and rank orders of responses.Socio demographic details shows that, highest number of respondents are female (57.14%), completed master/MPhil (51.42%), senior lecturer (57.14%) and interested in marketing (28.57%) as their research discipline. Respondents expressed their priority order for the factors considered to select journal to submit manuscript for publications, journal indexing is the highest priority. All the respondents have an idea about the open access publishing system. Respondents are expected to publish in open access journals because of high visibility, increasing citation number, prestigious journals and fast publication process in a frequency order. The result of the survey shows that, 97.15% of the respondents are knowledgeable about predatory publishing. Majority of the respondents are characterized, the predatory journals are, no insufficient peer review process, and Beall’s list of predatory journals used by the high number of respondents to differentiate legitimate journals from predatory journals. More than half of the respondents are satisfied with the services provided by the library to avoid publishing in predatory journals. Responses are summarized for each of the 8 statements about the impact of publishing in predatory journals. Almost all the statements are agreed by the respondents other than the statement of “Articles published in predatory journals are poor in quality”. Highest agreement found for the statement 3 which is “Predatory publications are not considered for any academic reward” in which 14out of 35 were strongly agreed and followed by the statement 2 “many researchers published articles due to lack of awareness about predatory publication” (13 out of 35). Finally respondents are suggested to organize more awareness session on open access publishing and journal selection to avoid predatory publishing.

Assessment of soil erosion risk and vulnerability in the transboundary Sio-Malaba-Malakisi watershed in Kenya and Uganda

Persistent soil erosion poses a significant threat to water quality, ecosystem viability and soil health in many regions of the world. Addressing this challenge requires a comprehensive understanding of local soil erosion rates, including the identification of vulnerable areas, to facilitate effective and integrated environmental management. In East Africa, however, many affected regions are data poor and lack measured hydrological data from which soil erosion estimates can be derived. This study used the physically based Revised Universal Soil Loss Equation (RUSLE) model to estimate the annual rate of soil erosion in the transboundary Sio-Malaba-Malakisi catchment, straddling Kenya and Uganda. Soil erosion events were quantified by integrating input factors derived from physical datasets using a Geographical Information System (GIS). The Analytical Hierarchy Process (AHP) technique was then used to assess the importance of selected physical factors influencing the soil erosion process in order to identify regions of increasing environmental vulnerability. The results obtained indicate a wide range of soil erosion rates across the region, with an estimated mean annual rate of 250 t ha−1 yr−1 for the whole catchment. Upstream areas characterized by intensive agricultural activity had erosion rates of up to 2000 t ha−1 yr−1, while downstream areas recorded erosion rates below 600 t ha−1 yr−1. Areas with intensive agriculture, unprotected soils, and a soil loss tolerance value above 12 t ha−1 yr−1 were found to be most vulnerable. Rainfall and vegetation cover were identified as key factors influencing erosion susceptibility. Regions with soil erosion rates above 50 t ha−1 yr−1 were identified as high priority regions for targeted soil and water conservation measures. The identification of vulnerability zones, including the classification of their severity, provides an opportunity to prioritize sustainable environmental management interventions; a process that can be replicated for such affected regions elsewhere.

Управление логистическими процессами в трансграничной электронной коммерции

In the context of the globalization of the economy and the development of cross-border e-commerce, the importance of cross-border logistics is increasing, allowing for an effective process of product distribution. The issues of organizing transport and logistics processes during the delivery of goods within the framework of the functioning of cross-border e-commerce are discussed. The main aspects of the development of e-commerce logistics and its impact on the trading business have been studied. An analysis of the cross-border e-commerce market in Russia is carried out. It is noted that currently the global logistics industry is in an unstable environment. The main directions and trends in the development of logistics services in modern conditions are considered and the specifics of adapting the process of goods distribution within the framework of cross-border e-commerce to changes in the external environment are investigated. The distinctive features of e-commerce logistics have been studied in the context of its impact on the trading business, which allows for increased efficiency of logistics processes such as procurement, transportation, order processing, inventory and warehouse management, packaging and labeling. It has been proven that with the development of information technology and telecommunication networks, as well as increasing demand in the field of online trading, the need for effective logistics support is significantly increasing, and delivery speed is becoming increasingly important to provide quality service to consumers. The advantages of e-commerce are substantiated from the perspective of subjects of trade and logistics activities, which include the global nature of customer coverage and the convenience of inter-subject interaction, reduction of operating costs of trade and logistics activities, expanded opportunities for marketing and advertising support, increased level of automation of e-commerce logistics management processes.

Nonlinear Ion Acoustic Waves in Multicomponent Plasmas with Nonthermal Electrons-positron and Bipolar Ions

Abstract This paper studied the propagating characteristics of (2+1) dimensional nonlinear ion acoustic waves in a multicomponent plasma with nonthermal electrons, positrons and bipolar ions. The dispersion relations are initially explored by using the small amplitude wave's dispersion relation. Then, the Sagdeev potential method is employed to study large amplitude ion acoustic waves. The analysis involves examining the system's phase diagram, Sagdeev potential function, and solitary wave solutions through numerical solution of an analytical process in order to investigate the propagation properties of nonlinear ion acoustic waves under various parameters. It is found that the propagation of nonlinear ion acoustic waves is subject to the influence of various physical parameters, including the ratio of number densities between the unperturbed positrons, electrons to positive ions, nonthermal parameters, the masses ratio of positive ions to negative ions, and the charge numbers ratio of negative ions to positive ions, the ratio of the electrons’ temperature to positrons’ temperature. In addition, the multicomponent plasma system has a compressive solitary waves with amplitude greater than zero or a rarefactive solitary waves with amplitude less than zero, in the meantime, compressive and rarefactive ion acoustic wave characteristics depend on the charge numbers ratio of negative ions to positive ions.

Book review | Conceptualizing, designing, implementing, and evaluating writing interventions

Conceptualizing, Designing, Implementing, and Evaluating Writing Interventions, edited by Fien De Smedt, Renske Bouwer, Teresa Limpo, and Steve Graham, emerges as a comprehensive guide for researchers navigating the many steps to developing a writing intervention. Writing interventions are changes to a writer’s traditional approach which are meant to improve a writer’s cognitive processes in order to become a more skilled writer. These interventions are often implemented in classrooms, from primary schools to post-secondary education. This volume offers a start-to-finish overview of the intervention research process. The structure mirrors its title, dividing its contents into four crucial stages of intervention research. These stages are grounded in previous volumes on writing intervention research in the Brill Studies in Writing Series, which provide insight into how writing interventions have changed over the years and demonstrate a pattern of research design. Additionally, the need for a shared framework is emphasized through both reports from the National Commission on Writing (2004) and influential writing models by Graham (2018a, 2018b) and Hayes (2012), which recognize the significance of motivational factors in writing.

Impact of Managerial Skills on Organizational Development: An Applied Study in the Regional Directorate of Transport and Communications of the Amazonas Region

This study analyzes the relationship between managerial skills and organizational development in the Regional Directorate of Transport and Communications of the Amazon Region during the year 2021. A quantitative approach with descriptive-correlational and non-experimental design was adopted, using a structured questionnaire applied to a sample of 72 workers. The results show that there is a low but significant positive evaluation between managerial skills (leadership, communication, decision making and motivation) and the dimensions of organizational development (planning, organization, integration and direction). The highest rating coefficient was Rho = 0.300, indicating a moderate relationship between managerial skills and overall organizational development. Although managerial skills influence process improvement and efficiency, other factors, such as organizational structure and available resources, also play a crucial role. It is concluded that it is essential to strengthen managerial competencies through continuous training programs and to improve internal processes in order to optimize organizational development in this public entity. Finally, it is suggested that other factors that may impact organizational development, such as technology and organizational culture, be explored in future studies.