One of the most pressing health problems worldwide is the fight against such common and socially significant parasites as toxoplasmosis. Epidemiology, prevention and rehabilitation of patients require careful study, as this invasion can lead to termination of pregnancy, stillbirth or birth of children with abnormalities of the central nervous system and visual organ, as toxoplasmosis chorioretinitis can result in complete loss of vision. It is known that congenital toxoplasmosis can be detected in decades by multifocal lesions of the central nervous system, auditory analyzer. Toxoplasmosis is characterized by polymorphism of clinical manifestations, which complicates the diagnosis of this disease; so far there are no specific methods of its prevention and rehabilitation programs. The causative agents of many parasitosis are potential biological threats, a number of these diseases, including toxoplasmosis, are associated with many immunodeficiency conditions, including HIV. The research aim was to improve the monitoring, regulation and improvement of the parasitological situation regarding toxoplasmosis in Ukraine by introducing a system of preventive measures against this invasion; development and use in the practice of medical institutions of methods of rehabilitation of patients with various forms of toxoplasmosis. Recommendations have been given to women on the prevention of congenital toxoplasmosis when planning a pregnancy. The need to improve the monitoring system and main ways to solve problems in diagnosis, prevention and rehabilitation of patients with toxoplasmosis, especially for the population at high risk has been demonstrated. The priority tasks are the development of leading parasitologists of Ukraine methodological recommendations, protocols and algorithms of actions for diagnosis, treatment, prevention and rehabilitation of patients with toxoplasmosis, the creation of appropriate regional centers, establishing a comprehensive national program to combat toxoplasmosis. Key words: toxoplasmosis, parasitosis, prophylaxis, rehabilitation.