Traffic sign detection is a research hotspot in advanced assisted driving systems, given the complex background, light transformation, and scale changes of traffic sign targets, as well as the problems of slow result acquisition and low accuracy of existing detection methods. To solve the above problems, this paper proposes a traffic sign detection method based on a lightweight multiscale feature fusion network. Since a lightweight network model is simple and has fewer parameters, it can greatly improve the detection speed of a target. To learn more target features and improve the generalization ability of the model, a multiscale feature fusion method can be used to improve recognition accuracy during training. Firstly, MobileNetV3 was selected as the backbone network, a new spatial attention mechanism was introduced, and a spatial attention branch and a channel attention branch were constructed to obtain a mixed attention weight map. Secondly, a feature-interleaving module was constructed to convert the single-scale feature map of the specified layer into a multiscale feature fusion map to realize the combined encoding of high-level semantic information and low-level semantic information. Then, a feature extraction base network for lightweight multiscale feature fusion with an attention mechanism based on the above steps was constructed. Finally, a key-point detection network was constructed to output the location information, bias information, and category probability of the center points of traffic signs to achieve the detection and recognition of traffic signs. The model was trained, validated, and tested using TT100K datasets, and the detection accuracy of 36 common categories of traffic signs reached more than 85%, among which the detection accuracy of five categories exceeded 95%. The results showed that, compared with the traditional methods of Faster R-CNN, CornerNet, and CenterNet, traffic sign detection based on a lightweight multiscale feature fusion network had obvious advantages in the speed and accuracy of recognition, significantly improved the detection performance for small targets, and achieved a better real-time performance.