ABSTRACT Household waste segregation is crucial for better domestic waste management, successful material recovery programs, environmental pollution reduction, and the promotion of circular economies. While prevalent in developed nations, global adoption of household waste segregation is lacking, particularly evident in emerging economies where city authorities grapple with mounting volumes of mixed waste. Our study, conducted in the Greater Accra Metropolitan Area, surveyed 1,245 households using a multi-stage sampling technique. Employing structural equation modeling, we assessed how descriptive, injunctive, and moral norms influence individuals’ intention to segregate household waste, considering sociodemographic attributes and policy effectiveness. Findings underscore the significance of descriptive and moral norms, affirming their impact on pro-environmental behaviors. The study reiterates the influential role of education, age, and neighborhood characteristics in moderating these norms and recommends the implementation of persuasive policies, like waste-for-cash incentives, backed by logistical support, infrastructure, and public education to foster household waste segregation and elevate waste management practices.