PurposeA wealth of studies have identified numerous antecedents to online self-disclosure. However, the number of competing theoretical perspectives and inconsistent findings have hampered efforts to obtain a clear understanding of what truly influences online self-disclosure. To address this gap, this study draws on the antecedent-privacy concern-outcome (APCO) framework in a one-stage meta-analytical structural equation modeling (one-stage MASEM) study to test a nomological online self-disclosure model that assesses the factors affecting online self-disclosure.Design/methodology/approachUsing the one-stage MASEM technique, this study conducts a meta-analysis of online self-disclosure literature that comprises 130 independent samples extracted from 110 articles reported by 53,024 individuals.FindingsThe results reveal that trust, privacy concern, privacy risk and privacy benefit are the important antecedents of online self-disclosure. Privacy concern can be influenced by general privacy concern, privacy experience and privacy control. Furthermore, moderator analysis indicates that technology type has moderating effects on the links between online self-disclosure and some of its drivers.Originality/valueFirst, with the guidance of the APCO framework, this study provides a comprehensive framework that connects the most relevant antecedents underlying online self-disclosure using one-stage MASEM. Second, this study identifies the contextual factors that influence the effectiveness of the antecedents of online self-disclosure.