The integration of Advanced Artificial Intelligence (AI) technologies in Printed Circuit Board (PCB) manufacturing has revolutionized the industry, offering significant improvements in defect prevention and yield optimization. As PCB manufacturing processes become increasingly complex and intricate, traditional methods of defect detection and quality assurance are often insufficient to meet the high demand for precision and efficiency. This paper explores the application of cutting-edge AI methodologies, including machine learning, computer vision, and neural networks, to address critical challenges in PCB production. The primary focus of this research is on the role of AI in enhancing automated defect detection systems and optimizing production yield. AI-based systems such as predictive maintenance, real-time process monitoring, and intelligent decision-making have been shown to drastically reduce defects while improving overall production throughput. Machine learning algorithms can identify subtle defects in real time, often undetectable by conventional methods, while neural networks can analyze historical data to predict potential failures before they occur. Additionally, AI-driven optimization techniques help manufacturers adjust production parameters dynamically, ensuring higher yields and minimizing waste. Through a combination of theoretical analysis and case studies, this paper highlights the effectiveness of AI-driven solutions in PCB manufacturing. Results from industry applications indicate significant improvements in both quality control and yield rates, providing a competitive edge to manufacturers adopting these technologies. Furthermore, this paper discusses future trends, including the integration of AI with the Internet of Things (IoT), edge computing, and sustainable manufacturing practices, which will further enhance the capabilities of AI systems in this field. The findings suggest that advanced AI technologies are not only capable of overcoming existing challenges in defect prevention but also hold the potential to reshape the future of PCB manufacturing by offering highly adaptive, precise, and efficient solutions. This research underscores the transformative impact of AI in modernizing manufacturing processes, making it an indispensable tool for the future of the PCB industry.