Modern tools of water supply systems monitoring at enterprises or in the housing sector use laser liquid sensing systems. In this case, as a rule, laboratory analyses of the obtained liquid samples are used, as well as spectral analysis methods when scanning the liquid with light for different wavelengths. These approaches do not allow for real-time analysis of a moving fluid flow (flow analysis). The paper considers a version for constructing of a system for online detecting and identifying emergency clots of pollutants in a liquid stream using laser radiation. The basic principles of the system construction, the block diagram of the system structure and parameters for identification of clots of substances under study flowing in the pipelines of the sewage or water treatment system at industrial enterprises are given. When constructing the system, several wavelengths of laser radiation are used, simultaneously directed to the one point of the studied clot of the studied fluid flow. Light wavelengths are determined at the stage of preparation for the study. At this initial stage of the process, optical transmission spectra of substances that are a priori possible in the studied fluid flow are analyzed. The main criterion for wavelengths choose is difference in substances optical transmission spectra at the se selected wavelengths. For the possibility of technical separation of signals at different wavelengths of the emitting radiation, the radiation fluxes are modulated. Creation of standards for identification substances in fluid flow clusters is carried out in the form of lattice functions containing the components of the substance optical transmission spectrum at certain wavelengths of laser radiation. Modulation of radiation is proposed to be carried out by controlling the pumping of each emitters of the system. The proposed system will find application in the oil and gas, processing industry, water filtration and purification systems, industrial enterprises and agricultural processing enterprises.