Prevalence Of Intestinal Parasitic Infections Research Articles

Prevalência e fatores de risco associados a infecções Infecções Parasitárias Intestinais (IPIs) em áreas rurais e urbanas de Quetta, Paquistão

Intestinal parasitic infections (IPIs) are endemic worldwide and more prevalent in countries with unhygienic conditions. The objective of the research was to identify the prevalence of intestinal parasitic infections in rural and urban areas of Quetta, Balochistan and to check their associated risk factors including; age, gender, educational status, sanitary system and any other immunodeficiency. For this instance 204 stool samples were collected from the urban and rural population of Quetta, Balochistan. The participants with positive results for Intestinal Parasitic Infections were interviewed using close-ended questionnaire. From the findings of this study, it has been revealed that prevalence of Intestinal parasitic infections in rural and urban areas was 21%. Males were found more prevalent (66%) as compared to females (34%) due to higher risk of contacting to outer environment. The prevalence was higher in rural areas (23%). The most prevalent intestinal parasite was Entamoeba histolytica (48%). Other prevailing parasites were Hymenolepis nana (26%), Giardia Intestinalis (17%), Trichomonas hominis (5%) and Trichuris trichiura (5%). The majority of patients were having lower socio-economic (52%) and educational status (48%). Educational status of 48% patients was primary or below primary. Most of the participants with positive results did not have hand washing habit (62%) and didn't have the closed sanitary system (71%). The intestinal parasitic infections were more prevalent among children aged from 1-10 (33%). This may be a result of poor hygiene in children. The study will contribute to lower down the prevalence in the studied areas by the application of different preventive measures in future.

Prevalence and Predictors of Intestinal Parasitic Infections at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, from 2019 to 2023: A Retrospective Study.

Parasitic infections are a primary cause of illness worldwide and a public health problem. This study highlighted the prevalence of intestinal parasitic (IP) infections and their updated epidemiologic status from 2019 to 2023 at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. A retrospective study was conducted from 2019 to 2023 at King Abdulaziz University Hospital. The laboratory results, socio-demographic information, and the year of data collection were collected from the hospital's parasitology laboratory. The data were analyzed using SPSS version 26. Ethical approval was obtained from the National Committee of Bioethics (NCBE) - King Abdul Aziz City for Science and Technology, with an approval number of 258-22. During the study period, 7673 stool samples were requested for intestinal parasite examination. The prevalence of IP infection from 2019 to 2023 was 212/7673, with a percentage of 2.8%. Infected patients had a mean (SD) age of 37.68 (17.27) years. Most infected patients were females (61%) and from Saudi Arabia (37.1%). Most stool samples were brown (79.1%), and about half were soft (51.7%). 2019 had the highest number of infected cases (28.3%), while the number of cases decreased in 2023 (8.8%), the lowest during five years. The most predominant parasite among study subjects was Blastocystis hominis (48.11%). The prevalence of IP infection is lower than in previous comparable surveys. Maintaining personal hygiene, conducting epidemiological surveillance, and enhancing environmental sanitation can prevent and control infections.

Pattern of Intestinal Parasitic Infection in School Children of District Malakand, Pakistan

Intestinal parasites either helminths or protozoans are a common health problem particularly in remote areas. This research was aimed to explore the prevalence of intestinal parasitic infection in school children of district Malakand, Pakistan. A total of 315 fecal specimens were examined by using direct smear methods and concentration techniques. Two hundred and fifty six (81.2%) children were found infected with one or more than one intestinal parasites. One hundred and sixty seven (53.2%) of the children were infected with single parasite and one hundred and four (32%) with multiple infections. Ascaris lumbricoides 26.0% (n=82/315), hookworm 13.9% (n=44/315), Trichuris trichura 4.75% (n=15/315), Hymenolepis nana 3.81% (n=12/315), Taenia saginata 2.51% (n=8/315) and Enterobius vermicularis 1.91% (n=6/315) were detected as single infection in order of their prevalence, multiple infections have also been observed. The male students were found more infected as compared to females (P<0.05). No significant association was recorded among the ages and parasitic infection (P<0.05). However, higher age groups were found more infected as compared to lower ones. Due to the fact that school children is coming in the group at higher risk for intestinal parasitic infection is especially important for investigation. Such studies should continue time to time to report the prevalence and impact of IPIs in the far flung areas of the country.

Current status of intestinal parasitic infections and associated risk factors in rural population of Guilan province, northern Iran: trichostrongyliasis is the most prevalent helminthic infection.

This study aimed to determine the distribution of enteric parasitic infections and related risk factors among rural communities of Guilan province, Northern Iran, and to compare the results with the situation in the past. Intestinal parasitic infections are still considered as a major public health concern, particularly in human communities with poor economy and sanitation. This cross-sectional study was performed in rural areas of Masal and Shanderman district from February to December 2020. A total of 917 stool samples were collected and examined for presence of intestinal helminthes and protozoa using direct, formalin-ether and Kato-Katz techniques. A total of 156 (17%) out of 917 examined individuals were infected with intestinal parasites. The overall prevalence of protozoa, helminths and mixed infections were 11.8% (108/917), 4.5% (41/917) and 0.8% (7/917), respectively. Blastocystis was the most prevalent intestinal protozoa (9.6%) followed by Giardia lamblia (1.9%), Endolimax nana (1.1%), E. coli (0.8%) and Entamoeba hartmani (0.1%). The highest prevalence of intestinal helminths belonged to Trichostongylus spp. (3.5%) and Strongyloides stercoralis (1.3%). Statistical analysis showed significant association between giardiasis and sex (P<0.03). On the other hand, prevalence of enteric helminths was influenced by close contact with livestock, keeping herbivorous animals at home, job, education, and consumption of uncooked vegetables (P<0.05). The findings indicate a decreasing trend in the prevalence of intestinal parasitic infections in Guilan province in comparison to the past few decades. Hookworm infections, which was very prevalent in the area, are now rare, while trichostrongylosis showed a high prevalence in rural residents of the study area.

Entry of Migrant Workers to Malaysia: Consideration to Implement Mass Drug Administration Against Intestinal Parasitic Infections.

Over the last five decades, widespread industrialisation and urbanisation have resulted in the influx of low-skilled workers, particularly from Southeast and West Asia to Malaysia. The current practice for migrant workers entry for employment requires mandatory medical screening for infectious diseases. However, screening for parasitic infections in Malaysia is woefully inadequate. Many migrants come from low-income countries where parasitic infections are common, which may have public health implications for their overall well-being as parasitic infections, although not critical, may impact their overall productivity. The high prevalence of intestinal parasitic infections (IPIs) recorded among migrant workers in Malaysia necessitates improvement in the national health policy to include mandatory mass administration of a single dose of anthelmintic drugs to all low-skilled migrant labourers, particularly upon entry into the country, admission, and encourage continuous surveillance. A constant stream of migrant labourers is anticipated, potentially resulting in an ongoing occurrence of parasitic infections within the population. The implementation of economic measures like health awareness initiatives, routine deworming campaigns, and improved sanitation facilities holds the potential to reduce the spread of these infections notably. More often than not, taking preventive actions proves to be more financially efficient over time compared to addressing severe infections at a later stage.

Enteric parasites and associated factors in cancer patients in Nepal.

Infection with intestinal parasites is widespread worldwide, especially in developing countries. Intestinal parasites are a major cause of diarrhea in both immunocompetent and immunocompromised people, but cancer patients are more prone to infection. This study aimed to investigate the prevalence and risk factors of intestinal parasitic infections (IPIs) among cancer patients undergoing chemotherapy at Nepal Cancer Hospital and Research Center (NCHRC) in Nepal. One hundred individuals were selected with a convenience sampling strategy. The stool samples were examined by direct wet mount, sedimentation, flotation, and acid-fast methods to determine the prevalence and intensity of IPIs in this population. The overall prevalence of IPIs was 8% (4% protozoan and 4% helminths). Altogether, three species of intestinal parasites were detected. Cryptosporidium (4%) was predominant followed by Trichuris trichiura (2%) and Ancylostoma duodenale (2%). Multivariable regression analysis revealed that "not using soap for handwashing" was significantly associated with the prevalence of overall IPIs. None of the other evaluated risk factors indicated an association with IPIs infection. In this study, the IPIs were attributable to individual hygiene behaviors, but not to nutritional status or socio-demographic characteristics. Yet, significant numbers of males reported anemia and undernutrition in this study population.

Prevalence of Intestinal Parasitic Infections among Children Attending Some Schools in Amran Governorate, Yemen

Intestinal parasitic infections (IPIs) are a global health issue among schoolchildren, with high morbidity and mortality. Therefore, this study aimed to determine the prevalence of intestinal parasite infections among schoolchildren in the Amran governorate, Yemen. Methods: This is a cross-sectional study carried out among 200 schoolchildren aged 7–15 years between December 2021 and March 2022. The stool specimens were collected and the parasite species was detected according to standard laboratory methods. Results: The overall rate of parasite infection was 48%. Entamoeba histolytica was the most prevalent parasite among children (25%), followed by Giardia lamblia (13.5%), Entamoeba coli (12%), Enterobius vermicularis (10%), and Hymenolepis nana (6.5%). Furthermore, a higher infection was among males (57%), those aged 7 to 10 (45%), those whose parents had a basic education (60.7%), and those who consume unwashed vegetables and fruits (57.7%). Additionally, a higher infection was among those who do not wash their hands after defecation (57.7%) and individuals who maintain their nails (54.8%). Conclusion: As a result of the high prevalence of IPIs among the study's participants, environmental sanitation, personal hygiene, and health education are all required for promotion in order to avoid parasitic infection among children

Prevalence of intestinal parasites in HIV/AIDS-infected patients with correlation to CD4+ T-cell count at hospital in Eastern India.

In developing nations, one of the most common reasons for death and illness is due to infections that are brought on by intestinal parasites. People who have HIV are more likely to contract parasites that are either well-established intestinal pathogens, like Entamoeba histolytica, Giardia lamblia and Strongyloidesstercoralis, or an opportunistic pathogen like Cryptosporidium, Isospora, Cyclospora and Microsporidia. Higher prevalence of intestinal parasitic infections occurs in patients with low CD4+ cell counts. Hence, this study had been performed to know the correlation of intestinal parasitic infection in HIV/AIDS patients with reference to CD4+ cell count. The study comprised 1477 HIV-positive patients who were treated at ART Centre of Rajendra Institute of Medical Sciences (RIMS), Ranchi. All participants provided verbal informed consent before specimens were collected. Blood and stool sample were used for the identification of parasite and CD4+ T-Cell count. In patients living with HIV, the prevalence of intestinal parasite infection was 12.59 per cent. In a manner parallel, the prevalence of parasitic infections was found to be 10.29% among male HIV-positive patients and 2.31% among female HIV-positive patients. This study has shed light that low CD4+ T-cell count appears to be a factor for intestinal parasitic infections and development of diarrhoea. Regular screening and treatment of intestinal parasitic infections is very important in overall improvement in quality of life of HIV/AIDS patients. Nevertheless, sanitary hygiene practices and deworming are needed to enhance the control of infection in the affected areas.

Prevalence of Intestinal Parasitic Infection Among the 1-15 Years Age Group Children and Its Association with Iron Deficiency Anemia

Background and Objective Intestinal parasitic infection and iron deficiency anaemia are still, a significant public health concern mostly in developing countries. The present study aimed to study the relationships between intestinal parasitic infections and iron deficiency anaemia among the 1-15 years age group of children. There are many helminths, transmitted through the soil like Ascaris lumbricoides (roundworm), Trichiuris trichiura (whipworm), Ancylostoma duodenale, and Necator americanicus (hookworms). These infections are most prevalent among the children Methods: In this study the stool samples were collected fro[i]m above age group children for parasitic infection and Hb, PBF examination was also conducted to rule out the anemia at verto medical lab. There may be chances of IDA because of the nutrition deficiency but if the occult blood positive and parasites in stool, suggestive of anemia due to the blood loss. Results: The sample was collected and processed out of that 19% samples were positive for intestinal parasites. Particularly the Entamoeba coli was 6%, E. histolytica was 2%, Ascaris and Giardia was 7%. Giardia percentage was high and fecal occult blood was positive of all sample containing parasites except Entamoeba coli, the FOB was negative. The patient with intestinal infection usually having low hemoglobin value and peripheral examination populated with predominately microcytic hypochromic picture. Conclusion: The reveals the relationship between the role of intestinal parasites in loss of iron that gives the impact on hemoglobin synthesis revealed in blood film examination. finding proof of IDA. The study also helpful in early diagnosis of IDA through few parameters mentioned in study.&#x0D; &#x0D;

PREVALENCE OF INTESTINAL PARASITES AND ASSOCIATED RISK FACTORS AMONG UNDER-FIVE CHILDREN ATTENDING KIBOGORA LEVEL TWO TEACHING HOSPITAL, RWANDA

This study aimed to assess the prevalence of intestinal parasites and associated risk factors among under-five children attending Kibogora Level Two Teaching Hospital in Rwanda. Specific objectives were: to determine the prevalence of intestinal parasites among under-five years children attending Kibogora Level Two Teaching Hospital, Rwanda, to identify the source of water and their utilization in intestinal parasitic occurrence among under-five years children attending Kibogora Level Two Teaching Hospital, Rwanda; and to identify the risk factors associated with intestinal parasites occurrence among under-five children attending Kibogora Level Two Teaching Hospital, Rwanda. Methods: retrospective cross-sectional study design with quantitative approaches at Nyamasheke in June 2022. The study includes a target population of 772 children and a sample size of 263. A questionnaire was administered to collect data on hygiene, sanitation, socio-demographic and economic characteristics (risk factors), and secondary data from 2019-2022 were used. Results: the prevalence of intestinal parasites was 102(38.7%). In this study the prevalence of Ascaris 56(21.3%) was the highest followed by amoeba (Entamoeba histolytica) 24(9.1%), Giardia lamblia 8(3.0%), Trichomonas intestinalis 7(2.6%) and Ankilostoma duodenale 7(2.6%). Other intestinal parasites detected such as Necator americanus and Trichiuris trichiura were identified at less than one percent prevalence. A chi-squared test was used to establish a relationship between different variables. The chi-squared shows that there is no statistically significant association between the marital status category of the children and having latrines at home with a chi-squared value of 3.293 and a p-value 0.183 of there was no statistically significant association. utensils drying site with a chi-squared value of 5.422 and p-value of .000 there was a statistically significant association. Drinking boiled water with a chi-squared value of 7.857a and p-value of .97. Washing hands before a meal with a chi-squared value of 7.857a and p-value of 98. Washing hands after defecation with a chi-squared value of 3.293 and p-value of .193, there is no statistical significance. Finally, the high prevalence of intestinal parasitic infections in under-five children warrants strict control measures for microbial reduction through the utensils-drying site, improved hygiene and sanitation, and treatment of drinking water should be considered.&lt;p&gt; &lt;/p&gt;&lt;p&gt;&lt;strong&gt; Article visualizations:&lt;/strong&gt;&lt;/p&gt;&lt;p&gt;&lt;img src="/-counters-/soc/0015/a.php" alt="Hit counter" /&gt;&lt;/p&gt;

Prevalence of Intestinal Parasites and Associated Risk Factors among Rural Areas in Duhok Province

Background: Intestinal parasitic infections in humans are considered a significant global issue, particularly in rural areas. The study aimed to determine the prevalence of intestinal parasite infections and their associated factors in rural areas in Duhok province-Kurdistan Region-Iraq.&#x0D; Methods: A total of 620 stool samples were collected from individuals of various ages residing in rural villages within districts of Duhok province and were subjected to microscopic examination techniques.&#x0D; Results: Among the participants, 62.26% were found to be infected with at least one or two species of intestinal parasites. The prevalence of intestinal parasites was higher in males (68.65%) compared to females (31.35%). The highest prevalence rate (34.46%) was observed in the age group between 6 and 12 years. The infection were three protozoa: Entamoeba histolytica (73.83%), Giardia lamblia (16.84%), and Blastocystis hominis (8.81%). only one helminths was detected: Taenia spp. (0.52%). Protozoan infection was higher than helminths infections (99.48% and 0.52%, respectively). Abdominal pain and diarrhea were reported with high rates (33.16% and 32.12%, respectively). Participants who consumed water from wells exhibited the highest rate of intestinal parasitic infections (62.44%). Those who did not wash their hands before meals (70.47%), consumed raw or unwashed vegetables and fruits (61.66%), and had contact with animals (80.57%) showed significantly higher prevalence rates of intestinal parasitic infections (P &lt; 0.05).&#x0D; Conclusions: The prevalence of intestinal parasites among rural populations was high in Kurdistan Region and it was associated with unhygienic conditions.

The Frequency of Intestinal Parasitic Infections in COVID-19 Patients: A Case-Control Study in Tehran, Capital of Iran.

The present study was done to evaluate the prevalence of intestinal parasitic infections (IPIs) in patients with COVID-19 in health care centers (Imam Reza and Golestan hospitals), Tehran, capital of Iran. By designing a matched case-control study, 200 fecal samples were collected for each of the COVID-19 patients and healthy individuals. Nasopharyngeal/oropharyngeal swab samples were collected from all participants for the diagnosis of COVID-19. RNA extraction was performed, and then real time reverse-transcription polymerase chain reaction (rRT-PCR) assay was applied to detect viral RNA. Considering the lung complications, 25%> lung complications was detected in 49 patients, 25-49% in 42 patients, and 50%≤ in 109 patients. Fecal samples were examined using different parasitological techniques. After nested-PCR, sequencing was applied to identify Cryptosporidium spp. and microsporidia spp. A relatively lower prevalence of IPIs was detected among control group (7.5%), than in COVID-19 patients (13%), though not significant (P=0.13). The most prevalent parasite among patients was Blastocystis sp. (6%). Also, 13.76% of IPIs were detected in inpatients with more than 50% lung complication. As well, a remarkably significant difference in IPIs was observed among diarrheic COVID-19 patients, in comparison with nondiarrheic patients (P < 0.00001). Moreover, the isolated sequences in the present study belonged to C. parvum subtype IIa and Enterocytozoon bieneusi genotypes D and Peru 8. In conclusion, more epidemiological and clinical research studies are needed to better understand the status and interaction of IPI in COVID-19 in Iran and other countries.

Prevalence of intestinal parasitic infections in HIV-positive and negative groups in some selected semi-urban areas in Nasarawa state, Nigeria

Objectives: The objective of the study is to determine the occurrence of intestinal parasites among human immunodeficiency virus (HIV)-positive and negative groups. Materials and Methods: A case–control study was conducted in four semi-urban areas in Nasarawa State. The study enrolled 422 participants. Stool samples were collected and examined for the presence of intestinal parasites. Blood sample was collected to investigate for HIV infection. Results: The overall prevalence of intestinal infections among HIV-positive individuals was 37.7% (78/207). For geohelminth infections, HIV-positive individuals were more commonly infected by hookworm at a rate of 9.7% (20/207). For Protozoa infections, HIV-positive groups were identified more with Giardia lamblia, at a rate of 8.2% (17/207). The binary logistic regression showed that factors significantly associated with parasite infections among HIV-positive individuals included being under 43 years of age (odds ratio [OR] = 2.192, confidence interval [CI]: 0.082, 3.736) and subjects with diarrhea (OR = 1.521, CI: 0.112, 2.891) for geohelminth parasite. While in the case of Protozoa infections, parasitic infections are higher among study subjects with diarrhea (OR = 1.767, CI: 0.111, 3.009). Conclusion: HIV-positive individuals are more susceptible to coinfections with hookworm (geohelminth) and G. lamblia (Protozoa), which are more prevalent among those with poor personal hygiene habits. This indicates a need for an integrated approach to hygiene promotion, surveillance, and treatment.

Prevalence and risk factors of intestinal parasitic infections among pregnant women in Taiz Governorate, Yemen: A hospital-based study.

Intestinal parasitic infections in pregnant women have been associated with severe adverse outcomes such as anemia, low birth weight, and mother and fetus morbidity and mortality. This study aimed to determine the prevalence of intestinal parasitic infection and its associated risk factors among pregnant women in Taiz, Yemen. A cross-sectional study was conducted between July 2022 and January 2023. Sociodemographic and other explanatory variables were obtained via face-to-face interviews using a structured questionnaire. The wet-mount and formol-ether concentration techniques were applied to identify the IPIs. Data were analyzed using SPSS, version 20, and p-values < 0.05 were considered statistically significant. An analysis of descriptive statistics and multivariate logistic regression was conducted. A p-value < 0.05 was deemed statistically significant. The study included a total of 393 pregnant women. Of the 393 pregnant women screened for intestinal parasites, 144 (36.6 %) had at least one parasite. The most common intestinal parasite was Giardia lamblia (12.2 %), followed by Ascaris lumbricoides (10.9 %), Entamoeba histolytica/dispar (7.4 %), Enterobius vermicularis (14.3 %), and Hymenolepis nana (1.8 %). Being a farmer (AOR = 2.7, 95% CI: 1.69-4.26, p = 0:003) and drinking from unsafe water wells, streams, rain, and dams (AOR = 2:6, 95% CI: 1.68-4.25, p ≤ 0:001) were significantly associated with IPIs. Pregnant women in the study area still face a severe health burden due to intestinal parasitic infection. Therefore, it is recommended that health education should be improved, and safe tap water should be provided to pregnant women to reduce the incidence of IPIs.

Prevalence of Intestinal Parasitic Infections among children in Kirkuk City, Iraq.

Intestinal parasites are endemic in many developing areas, and they are regarded as one of the most frequent tropical diseases, where they are responsible for adult and child morbidity and mortality. The current study is a survey to determine the prevalence of intestinal parasite infections in patients attending the General Hospital for Pediatrics in Kirkuk City from January 2021 to September 2021. Stool samples were examined by direct smear method with normal saline 0.9 % NaCl and 1% iodine-Lugol solution staining method to determine the outcomes of the current investigation. The results were assessed using the Q-square statistic test. The current study's findings revealed that intestinal parasites were reported in 69(31.7), the most affected group of patients with intestinal parasites, those 1-3 years old (11.4%), Intestinal protozoa infection were (24.3%) significantly more than helminths with (7.4%). The most common protozoa were Entamoeba histolytica (17.9%), the next common protozoan found was Giardia lamblia (6.4%). Intestinal helminth infections were reported in this study (7.4%). Males were more infected with intestinal parasites (18.4%) than females (13.3%). The highest infection rate with intestinal parasites was recorded between August (6.4%) and September (4.6%). Double infection was detected in three cases with Entamoeba histolytica and Giardia lamblia. At the same time, no triple infection was reported during this study. Keywords: Intestinal parasitic infections, Intestinal protozoa, Intestinal helminths, Kirkuk

Prevalence of Intestinal Parasitic Infections, Genotypes, and Drug Susceptibility of Giardia lamblia among Preschool and School-Aged Children: A Cross-Sectional Study in Thailand.

This study aimed to estimate the prevalence of intestinal parasitic infections in children and assess the drug susceptibility and genotypes/assemblages of Giardia lamblia in Thailand. This cross-sectional study was conducted among children aged 3-12 years in Sangkhlaburi District, Kanchanaburi Province, Thailand, between 25 September 2017 and 12 January 2018. Parasites were identified by stool microscopic examination, cultivation of intestinal parasitic protozoa, and enzyme-linked immunosorbent assay (ELISA). Drug susceptibility and genotype of G. lamblia were performed, respectively, by a resazurin assay and Triosephosphate Isomerase A and B genes using modified primers and probes. Among the 661 participants, 445 had an intestinal parasitic infection, resulting in a prevalence of 67.32% (95% CI: 63.60-70.89%). Blastocystis hominis was the most prevalent protozoa infection (49.32%; 95% CI: 45.44-53.22%), while Ascaris lumbricoides was the most prevalent helminth infection (0.91%; 95% CI: 0.33-1.97%). The prevalence of G. lamblia was 17.40%, with genotype B being the most common. According to our study, intestinal parasitic infections were commonly found in Thai children. G. lamblia was the most common pathogenic protozoa infection identified and exhibited less susceptibility to metronidazole compared to furazolidone and mebendazole.

PREVALENCE OF INTESTINAL PROTOZOA, HELMINTHES, AND COCCIDIAN INFECTIONS AMONG PRIMARY SCHOOL CHILDREN IN THALA’A DISTRICT AT AMRAN GOVERNORATE, YEMEN

Background and objectives: The prevalence of intestinal parasite infection, which can range between 18% and 90%, is one of the most frequently reported diseases in Yemen and poses a serious health issue for schoolchildren. In Thala’a District, Amran Governorate, Yemen, the study's main goal was to ascertain the prevalence of intestinal parasite infection among primary school students. Subjects and methods: A cross-sectional survey was conducted from January to April 2022 among 400 schoolchildren, in the age groups 7-12 years. All the children were residents of the city of Thala’a. A pre-tested structured questionnaire was used to collect data. Stool samples were examined for intestinal parasites according to standard laboratory methods. Results: The children's ages ranged from 7 to 12 years, with a mean±SD of 9.52 ± 2.9 years. The results showed that 136/400 (34%) of the tested children were positive for intestinal parasite infection with a higher prevalence of specific intestinal worms (50.4%) than protozoa (33.3%) and coccidian infection (16.3%). The rate of infection alone was also higher than that of multiple parasitic infections (19.3% vs. 14.8%). The highest number of intestinal parasites was 50/400 (12.5%) for Ascaris lumbricoides, and 49/400 (12.25%) for Entameba histolytica followed by 9.8% for Giardia lamblia, 11.5% for Entrobius vermicularis, 6.5% for Cryptosporidium species, 6.5% for Hymenolepis nana, 2% for Schistosoma mansoni, and 0.8% for Trichuris trichiura. Considering the associated factors, boys had a higher infection rate than girls (50% vs. 24.2%) with an OR of 2.6, CI =1.7–3.9 (p &lt; 0.001). A higher rate was also recorded in older children (41%) with an odds ratio of 1.6 (p=0.03). Conclusion: There is a high prevalence of intestinal parasites among school children in Thala’a city, and various control measures are required to control and prevent intestinal parasites among school children. Peer Review History: Received: 3 March 2023; Revised: 22 April; Accepted: 27 June 2023, Available online: 15 July 2023 Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, asia_abdullah65@yahoo.com Received file: Reviewer's Comments: Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Rola Jadallah, Arab American University, Palestine, rola@aauj.edu Dr. Tamer Elhabibi, Suez Canal University, Egypt, tamer_hassan@pharm.suez.edu.eg Dr. Sheikh Abdul Khaliq, Department of Pharmacy Practice, Faculty of Pharmacy, Hamdard University, Karachi, Pakistan, drwadhsheikh1974@gmail.com

Prevalence and associated risk factors of intestinal parasitic infections among children in pastoralist and agro-pastoralist communities in the Adadle woreda of the Somali Regional State of Ethiopia.

Intestinal parasitic infections (IPIs) can cause illness, morbidity, and occasional mortality in children. Agro-pastoralist and pastoralist children in the Somali Regional State of Ethiopia (ESRS) are especially at risk for IPIs, as access to safe water, sanitation, and health services is lacking. Minimal data on the prevalence of IPIs and associated risk factors exists in this region. We assessed the prevalence of IPIs and associated risk factors during the wet season from May-June 2021 in 366 children aged 2 to 5 years in four agro-pastoralist and four pastoralist kebeles (wards) in Adadle woreda (district) of the Shebelle zone, ESRS. Household information, anthropometric measurements, and stool samples were obtained from included children. Parasites were identified microscopically using Kato-Katz and direct smear methods. Risk factors were assessed using general estimating equation models accounting for clustering. Overall prevalence of IPIs was 35%: 30.6% for single infections and 4.4% for poly-parasitic infections. Intestinal protozoan prevalence was 24.9%: 21.9% Giardia intestinalis, and 3.0% Entamoeba spp.. Intestinal helminth prevalence was 14.5%: 12.8% Ascaris lumbricoides, 1.4% hookworm (Ancylostoma duodenale /Necator americanus.), and 0.3% Hymenolepis nana. G. intestinalis infection was associated with drinking water sourced from the river (aOR 15.6, 95%CI 6.84, 35.4) and from collected rainwater (aOR 9.48, 95%CI 3.39, 26.5), with toilet sharing (aOR 2.93, 95%CI 1.36, 6.31) and with household ownership of cattle (1-5 cattle: aOR 1.65, 95%CI 1.13, 2.41; 6+ cattle: aOR 2.07, 95%CI 1.33, 3.21) and chickens (aOR 3.80, 95%CI 1.77, 8.17). A. lumbricoides infection was associated with children 36 to 47 months old (aOR 1.92, 95%CI 1.03, 3.58). Improving access to safe water, sanitation, and hygiene services in Adadle and employing a One Health approach would likely improve the health of children living in (agro-) pastoralist communities in Adadle and the ESRS; however, further studies are required.

An observational study of the prevalence of intestinal parasite infections in patients with chronic kidney disease

Abstract Objectives: The objective of this study was to ascertain the prevalence and relationship between intestinal parasite infections (IPIs) and the severity of chronic kidney disease (CKD). Methods: One hundred and forty-two adult patients (18 years of age) with established CKD were compared to 30 controls in a case–control descriptive observational study. The primary outcome measures were the prevalence of IPIs in CKD patients and healthy controls. The secondary outcome measures were the association of IPIs with the severity of kidney disease. Results: Twenty one (14.8%) participants in the study group and 7 (23.3%) in the control group had IPIs (P = 0.278). Among the organisms causing IPI, hookworm and Entamoeba histolytica were the most common as seen in 23.8% of cases and 19.1% of cases, respectively. In different stages of CKD, the prevalence of IPI showed an increase with the increase in the grading (r = 0.2547, P = 0.036). However, the type of IPIs were similar in all three grades. Conclusion: IPIs are common among CKD patients and healthy populations in developing countries. The increasing severity of CKD increases the occurrence of IPI owing to increased uraemia and decreased immunity. Monitoring of such cases may help in improving the outcomes of such patients.

Prevalence of intestinal parasites during pre- and post-COVID-19 pandemic at a tertiary care center in Lebanon

Introduction: Intestinal parasitic infections (IPIs) are a major medical and public health problem, especially in developing countries. This study aimed at comparing the prevalence and types of IPI during pre- and post-COVID-19 pandemics, and with data reported in Lebanon a decade ago. Methodology: Stool specimen results from a total of 4,451 and 4,158 patients were examined using the concentration method during the pre-covid (2017-2018) and post-covid (2020-2021) pandemic periods, respectively. Demographic information related to patient’s age and gender was recorded. Results: The overall positive detected parasites among the total tested in these two periods were 589 (13.2%) and 310 (7.5%), respectively. The protozoa accounted for most parasites (e.g., Blastocystis hominis, Entamoeba coli (E. coli), Entamoeba histolytica, and Giardia lamblia). Only B. hominis and E. coli showed significant differences; B. hominis was more prevalent in the post-covid period (33.5%) whereas E. coli in the pre-covid phase (44.5%). Among gender, E. histolytica was higher in males during the post-covid period (13.3% vs. 6.3%). Regarding age, adults (between 26 and 55 years) had the highest prevalence, with a noticeable decrease among the elderly in the post-covid time. Compared to the previous decade, the prevalence of B. hominis and E. coli remained higher, and that of E. histolytica and G. lamblia was almost the same. Conclusions: These findings indicate an overall reduction in the prevalence of IPI during the post-covid period, though IPIs persistence remains high. This highlights the need for enhancing public health awareness efforts to improve hygiene and sanitation to reduce parasitic prevalence in Lebanon.