Global Pressure Research Articles

Right ventricular pressure-strain-volume loop-derived myocardial work for the noninvasive assessment of volume overload-induced dysfunction in patients with secondary tricuspid regurgitation

Abstract Development of secondary tricuspid regurgitation (TR) is associated with poor outcomes in patients with left-sided cardiac diseases. Severe TR imposes substantial volume overload (VO) on the right ventricle (RV), inducing a vicious circle of progressive RV remodelling and dysfunction. Although previous studies have established the value of speckle tracking echocardiography (STE)-derived strain and pressure-strain loop-derived myocardial work indices, these metrics neglect chamber geometry, limiting their utility in conditions accompanied by VO. Accordingly, we aimed to (1) incorporate instantaneous RV volume into myocardial work calculation to define a method capable of detecting VO-induced RV dysfunction using 3D echocardiography (3DE) and (2) to test its prognostic power in patients with secondary TR. We enrolled 195 patients (age: 64±15 years, 69% male) with left-sided cardiac diseases and followed them for a median of 42 months. The primary endpoint was all-cause mortality. TR severity was graded according to current guidelines and we compared patients with significant (moderate+) TR (sTR, n=85) versus non-significant TR (nsTR, n=110). All patients underwent 3DE to measure left (LV), and RV volumes and ejection fractions (EF). A reference RV pressure curve was constructed using previously acquired right heart catheterization data and was individually adjusted by non-invasively estimated RV pressures. To obtain RV pressure-strain loops and global myocardial work index (GMWI), RV pressure and 3DE-derived RV circumferential strain tracings were concatenated. We further adjusted GMWI to instantaneous RV volumes (GMWIV) and constructed pressure-strain-volume loops (Figure 1). Twenty-three patients (11.8%) died during follow-up (16 out of 85 in the sTR group, and 7 out of 110 in the nsTR group). There were no differences in LV and RV volumes and EFs between the sTR and nsTR groups. Interestingly, patients with sTR had significantly higher values of GMWI (sTR vs. nsTR; 667 [438-879] vs. 567 [414-770] mmHg%, p=0.01), whereas GMWIV (292 [169-467] vs. 282 [170-399] mmHg%/mL, p=0.57) did not show difference. We compared patients with versus without adverse outcomes within the sTR group. Patients with sTR who died, presented with significantly lower volume-adjusted GMWIV values (dead vs. alive; 158 [122-332] vs. 312 [207-502] mmHg%/mL, p=0.02), while GMWI did not differ. By Cox regression analysis, GMWIV (hazard ratio [95% CI]: 0.997 [0.994-1.000], p<0.05) was a significant predictor of all-cause mortality in the entire population, whereas GMWI was not. By integrating RV volume into the pressure-strain relationship, our novel metric could detect the detrimental effects of VO on RV function with prognostic implications in patients with secondary TR. Our approach can be able to capture VO-induced subclinical RV dysfunction that conventional echocardiographic metrics could not unveil.Figure 1

Non-invasive estimation of left ventricular systolic peak-pressure: a prerequisite to calculate of myocardial work in hypertrophic obstructive cardiomyopathy

Abstract Introduction Myocardial work (MW) is an echocardiographic parameter to estimate global and regional myocardial performance. This method utilizes pressure strain loops derived from global longitudinal strain (GLS) and left ventricular systolic pressure (LVSP) estimated by brachial blood pressure (BP). Purpose Since LVSP cannot be equated with BP in pts with HOCM, we investigated whether the LVSP can be calculated non-invasively by combining Doppler echo parameters and the BP. This estimation is mandatory to make MW applicable for HOCM-pts. Methods We studied 20 consecutive pts (8 women, 12 men; mean age 57.0±13.9 years; NYHA class 2.1±0.8) with indication for first alcohol septal ablation. 6 pts had hypertension and 2 pts unexplained syncope. 18 (90%) pts were in sinus rhythm. NTproBNP was 1431 pg/ml (1912 IQR). Echo baseline measurements showed subaortic septal (IVS) thickness of 21.0±5.0 mm and maximal IVS thickness of 24.7±6.3 mm. Pts showed high-normal left ventricular ejection fraction (70.4±10.1%). Left atrial (LA) volume was 101.2±26 ml. All measurements of pressures and gradients were performed in the catheterization laboratory after placement of a 5F Judkins JR4 in the ascending aorta and a 5.2F special pigtail catheter in the apex of LV beyond the obstruction. Simultaneous measurements of BP at left upper arm, echo intraventricular gradients (instantaneous and mean) with CW Doppler (GE Vivid E70), and invasive pressures and gradients (peak-to-peak and mean) of the LV and ascending aorta were performed. Echo and invasive gradients were averaged over 3 cardiac cycles. Finally, we tried to identify an estimation of invasively measured LV systolic pressure by combining systolic BP and echo measured gradients. Results Systolic BP was 143±21 mmHg. Max. CW Doppler gradient was 65±29 mmHg and mean gradient was 31±14 mmHg. Invasive simultaneous measurements at rest showed peak-to-peak gradient of 55±24 mmHg and mean gradient of 34±13 mmHg between apical LV and ascending aorta. Mean LVSP was 190±40 mmHg. Systolic pressure of the ascending aorta was 134±28 mmHg. Adding systolic peripheral BP and maximal echo-gradient mean value was 208±38 mmHg. Adding systolic peripheral BP and echo-mean gradient mean value was 174±26 mmHg. Correlating these values with the invasively measured systolic LV pressure we found a slightly higher correlation of the sum of systolic BP and mean-echo gradient (Pearson correlation coefficient: 0.867 p<0.001) compared with the sum of systolic BP and maximal echo-gradient (Pearson correlation coefficient: 0.851; p<0.001). Bland–Altman plots demonstrated good levels of agreements between invasively measured LVSP and both non-invasively estimated LVSP. Conclusions Non-invasive estimation of LVSP is feasible by combining conventional BP and CW Doppler measured mean LV outflow tract gradient in HOCM. Hereby estimation of MW in pts with HOCM is applicable.

The prognostic power of two-dimensional strain-derived left ventricular myocardial work for all-cause mortality in pancreatic ductal adenocarcinoma patients receiving cancer therapy

Abstract Background Left ventricular (LV) myocardial work (MW) is a relatively novel parameter derived from the integration of LV global longitudinal strain (GLS) and LV pressure. MW may provide additive information beyond LV ejection fraction (EF) and GLS. However, the clinical implication of MW in pancreatic ductal adenocarcinoma (PDAC) patients receiving cancer therapy is still unclear. Purpose We conducted this prospective cohort study to investigate the clinical implication and the prognostic valve of LV MW in PDAC patients receiving cancer therapy. Methods We prospectively enrolled a total of 234 newly diagnosed PDAC patients (65.1±11.1 years old, 51% male). We did echocardiographic study at the following timepoints: before chemotherapy and 3 months after cancer therapy. MW parameters, including global work index (GWI), global constructive work (GCW), global waste work (GWW) and global work efficiency (GWE), would be determined from the pressure-strain loop. A ≥15% reduction in absolute GLS value from baseline was defined as signifying cancer therapy–related cardiac dysfunction (CTRCD). The primary outcome was defined as all-cause mortality. Results A total of 185 patients (64.7±11.3 years old, 49% male) were included for analysis. We excluded 49 cancer patients who did not have echocardiographic studies at 3 months after cancer therapy. Over a median follow-up of 8 months, twenty-six (14.1%) patients had CTRCD and sixty (32.4%) patients were dead. There was no significant difference of baseline demographic and echocardiographic parameters between the survivors and the mortality patients. At 3 months after cancer therapy, compared to the survivors, the mortality patients had lower LV EF (survivor vs. death: 68.6±6.5% vs. 63.5±11.3%, p=0.002) and lower GLS (survivor vs. death: -18.8±2.2% vs. -17.3±3.4%, p=0.003). Moreover, the mortality group had lower GWI (survivor vs. death: 1984.2±376.0 mmHg% vs. 1746.8±495.1 mmHg%, p=0.002) and GCW (survivor vs. death: 2307.0±405.6 mmHg% vs. 2125.1±493.9 mmHg%, p=0.02). After adjusting for age, gender, LVEF (at 3-month), GLS and CTRCD, GWI <1700 mmHg% was independently associated with all-cause mortality (hazard ratio 2.35, 95% confidence interval 1.37–4.03, p<0.001; Figure). Conclusion Approximate 14% of PDCA patients receiving cancer therapy had CTRCD. Lower values of LV GWI (<1700 mmHg%) was independently associated with increased all-cause mortality at a median follow-up of 8 months. LV GWI showed the better performance for mortality prognostic power compared to LVEF and LV GLS in PDCA patients receiving cancer therapy.

Non-invasive measurement of global myocardial work to predict all-cause death and heart failure hospitalization in non-ischemic cardiomyopathy

Abstract Background Global myocardial work (GMW) can be non-invasively calculated using a dedicated software using global longitudinal strain (GLS) and blood pressure. The prognostic value of GMW in patients with non-ischemic cardiomyopathy (NICM) has not yet been demonstrated. Purpose To stablish the prognostic significance of GMW in NICM. Methods Patients with NICM with an available echocardiogram between 2015 and 2019 and left ventricular ejection fraction (LVEF) <50% were retrospectively included. A dedicated software was used to analyze GMW, global constructive work (GCW), global wasted work (GWW) and global work efficiency (GWE). All quantitative variables were modelled as a spline with three knots to account for non-linear associations. Patients were followed up until the occurrence of death, heart failure hospitalization or lost to follow-up. The primary endpoint was a composite of all-cause death of heart failure hospitalization (HFH). Results A total of 524 patients with NICM in whom GMW analysis was feasible were included in the study. Median LVEF was 35 (IQR 27 – 42), and median GMW was 968 (IQR 670 – 1282). There were no significant differences in clinical characteristics between patients with GMW above or below median, except for higher rates of HFH during the previous year in patients with lower GMW. Patients with lower GMW displayed lower LVEF, greater LV dilatation, worse GLS, lower TAPSE and a higher E/e’ ratio (Table 1). GMW and GCW were significantly collinear with GLS (Pearson’s r = -0.85 and -0.83 respectively, p<0.001), GWE was moderately collinear (Pearson’s r = -0.64, p<0.001) whereas GWW was not (Pearson’s r = 0.05, p = 0.23). During a median follow-up of 4.8 years, 164 (31.3%) patients presented the primary endpoint. After adjusting for age, LVEF, end-diastolic volume and TAPSE, GMW showed a significant, non-linear association with the primary endpoint (Figure 1), at the expense of both death and HFH when separately analyzed. Risk progressively increased with a GMW below 2500 mmHg% and plateaued at 1000 mmHg%. Only GCW retained an association with the primary outcome like the one observed with GMW, whereas GWW and GWE did not. Adding GMW to the model led to an improved risk discrimination (AUC increased from 0.66 to 0.69, p = 0.043). Conclusions Global myocardial work and GCW are new independent echocardiographic predictors of all-cause death and HFH in NICM, with higher rates of the outcome at lower GMW and GCW values, whereas GWW and GWE were not associated with event rates in NICM.

Competition Law and Policy in the Global South: Power, Coercion and Distribution

Abstract Countries in the Global South have adopted competition laws and pursued competition policies very similar to countries in the North. This arrangement can be traced to various coercive powers at play—from trading partners in the North, international organizations to development banks, among others. As a result, the adopted laws are often unsuitable to the local needs of the countries in the South and their enforcement policies are often shaped by global pressure. This has alienated countries in the Global South from pursuing competition enforcement policies that could be empowering to their firms, consumers and communities at large. One way to resist and challenge these coercive powers is to pursue alternative competition policies, not alien to the Western nations themselves. In these alternative configurations, competition laws are squared with goals of industrialization and distributive equality. Pursuing these alternative competition goals challenges the dominance of the static model of competition policy aiming to achieve allocative efficiency. Examples from many places around the world are illustrated to show how competition policy, at crucial times of their development, were broadened to encompass an industrial agenda. The latter, more suitable for countries in the South, is discussed as a means of counter-coercion. It is discussed alongside an elaborate program for distribution to assure that the benefits of industrialization do not befall upon only a few. The aim of such a distributive program, built into competition enforcement, is to bring social justice concerns within the purview of competition policy.

Structure and variations of global planetary boundary layer top from 2008-2022 multiple GNSS RO observations

The structural changes at the planetary boundary layer (PBL) top are very complex and closely related to climate and environmental changes. With the development of Global Navigation Satellite System Radio Occultation (GNSS RO), it provides a good opportunity to estimate and study PBL variations. In this paper, long-term variations and structures of planetary boundary layer height (PBLH) from 2008 to 2022 are investigated by the Wavelet Covariance Transform (WCT) method based on refractivity profiles from Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) and Korea Multi-purpose Satellite-5 (KOMPSAT-5). Furthermore, the temperature and pressure of PBL top are detected using the temperature and pressure profiles from COSMIC and KOMPSAT-5 occultation data. The results demonstrate the latitudinal distribution of the PBL top height, temperature, and pressure, with the more apparent temperature's latitudinal characteristics. The pressure is more strongly correlated with PBL height than temperature. The PBL height in most land and oceans is high in summer and low in winter, and the PBL pressure is low in summer and high in winter, according to seasonal variation characteristics. The global PBL temperature is high in summer and low in winter, which is more obvious in high latitude region. A positive correlation between latitude and the magnitude of seasonal variation in PBL temperature is observed worldwide. Seasonal variation is less pronounced in the Southern Hemisphere (SH) than in the Northern Hemisphere (NH) due to sea-land differences. The annual average value of the global PBL height, temperature, and pressure do not change significantly over the long term, and also there is no a discernible upward or downward trend.

Understanding biochemistry: basic aspects of statistics for life sciences.

If the biological world is one thing it is variable. As scientists we seek to measure, quantify and explain the causes of this variation. The approach we take to this is remarkably similar whether our research is exploring global temperature, blood pressure, cancer incidence or enzyme kinetics. This approach involves defining clear research questions and applying statistical methods to answer them robustly. This article will introduce a practical example that will be used throughout, specifically whether genetic variation can explain variation in coffee consumption. We assume little experience with statistics and walk through the statistical approach that biologists can use, firstly by describing our data with summary statistics and then by using statistical tests to help arrive at answers to our research question. A General Linear Model (GLM) approach will be used as this is what many common statistical tests are. We explore how to visualise and report results, while checking the assumptions of our analysis. The better we can understand and apply statistics to biological problems, the better we can communicate results and future research to others. The popular statistical programming language R will be used throughout.

Patterns of change in coral reef communities of a remote Maldivian atoll revisited after eleven years

Coral reefs are exposed worldwide to several global and local human pressures including climate change and coastal development. Assessing the effects of such pressures on coral reef communities and the changes they undergo over time is mandatory to understand their possible future trends. Nonetheless, some coral reefs receive no or little scientific attention, as in the case of Huvadhoo Atoll that is an under-studied region in the southernmost area of the Maldives (Indian Ocean). This study analyzes the changes occurring over time in eight coral reefs (four inner reefs within the atoll lagoon and four outer reefs on the ocean side) at Huvadhoo Atoll, firstly surveyed in 2009 and revisited in 2020 using the same field methods. The cover of 23 morphological benthic descriptors (including different growth forms of Acropora) was taken into account and then grouped into three categories (i.e., hard coral, other benthic taxa and abiotic descriptors) to analyze the change in the composition of the coral reef community. Significant changes (e.g., increase in hard coral cover and decrease in abiotic descriptors) were observed in the inner reefs as compared to the outer reefs, which showed less variability. A significant decrease in tabular Acropora cover was observed in both inner and outer reefs, with possible negative effects on reef complexity and functioning. By comparing two time periods and two reef types, this study provides novel information on the change over time in the community composition of Maldivian coral reefs.

Sustainable strategy as a lever for corporate legitimacy and long-term competitive advantage: an examination of an emerging market multinational

PurposeThe purpose of this paper is to examine the process of integrating sustainability into the corporate strategy of an emerging market multinational enterprises (EMNE) to achieve and maintain corporate legitimacy over time. The research explores how deploying a corporate sustainability strategy enhances the company’s long-term competitive relevance by creating and maintaining corporate legitimacy and transferring practices based on sustainable development goals within the organization.Design/methodology/approachThe study adopts a qualitative single-case design, focusing on a corporate energy services company (Interconexión Eléctrica S.A.) operating in volatile, uncertain and turbulent environments.FindingsThe findings indicate that integrating sustainability into the corporate strategy enables subsidiaries to effectively meet global requirements, considering internal and external pressures. This integration also fosters the development of unique capabilities and the internalization of standards, addressing liabilities in foreign markets, thus providing a competitive advantage and safeguarding corporate legitimacy among stakeholders.Originality/valueThis research contributes to the international business literature by providing insights into strategy development and implementation in EMNEs. Specifically, it demonstrates how a Latin American emerging multinational enterprise (multilatina) adopts new sustainability strategies to enhance its business competitiveness. The study also offers guidance for emerging market companies on developing sustainability strategies and transferring them to subsidiaries operating in complex institutional environments. Furthermore, the research provides a rationale for governments and civil society organizations on why firms are committed to sustainability, highlighting its positive impact on firm’s competitiveness and survival in international markets.

Temporal variations of carbon and water fluxes in a subtropical mangrove forest: Insights from a decade-long eddy covariance measurement

Mangroves, highly efficient ecosystems in sequestering CO2, are strongly impacted by climate change. The lack of long-term observation in mangroves hinders the evaluation of seasonal and inter-annual variability in carbon and water fluxes and their responses to various environmental drivers. In this study, we measured net ecosystem CO2 exchange and evapotranspiration between the atmosphere and subtropical mangroves using the eddy covariance technique over a decade (2010–2019) in southern China. This mangrove forest acted as a strong CO2 sink, with annual net ecosystem production (NEP) ranging from 622.5 to 832.8 g C m−2 year−1. The annual evapotranspiration (ET) varied between 934.6 and 1004.9 mm year−1. During the study period, ET consistently remained higher in the wet season (May to October) compared to the dry season, while NEP did not exhibit consistent seasonal variation. Path analysis indicated that during the dry season, NEP was primarily influenced by global solar radiation and vapor pressure deficit. However, in the wet season, NEP was regulated by a combination of global solar radiation, vapor pressure deficit, air temperature, and tidal inundation time. Additionally, the promoting effect of global solar radiation on NEP decreased in the wet season, while the inhibitory influences of higher temperature and vapor pressure deficit on NEP intensified during the period. Unlike NEP, the dominant factors affecting ET (global solar radiation, air temperature, and vapor pressure deficit) and their intensities remained relatively consistent during both seasons. Furthermore, the relative importance of global solar radiation on NEP and ET increased over the decade, while the influence of tidal inundation time diminished. This study not only improves the understanding of the response of subtropical mangroves to climate change but also provides a valuable benchmark dataset to validate the interannual variability of mangrove carbon and water fluxes estimated from the models.

Fast-Responding Pressure-Sensitive Paint Measurements of the IC3X at Mach 7.2

Global surface pressure measurements of a 5.7% scale AFRL Initial Concept 3.X vehicle (IC3X) were obtained using a fast-responding ruthenium-based pressure-sensitive paint (PSP) at the UTSA Mach 7 Ludwieg Tube Wind Tunnel at two different angles of attack, 0° and 2.5°. Static calibration of the paint was performed over a range of 0.386 kPa to 82.7 kPa to relate luminescent intensity to pressure. Details on the facility, paint preparation, application, calibration, and image processing techniques are provided in the manuscript. The results from statistical, spectral, and proper orthogonal decomposition (POD) analyses are presented to characterize the pressure field observed on the model. The experimental results qualitatively follow the expected trends and correspond to the occurrence of shock waves and expansion fans, which were visualized via Schlieren imaging. The theoretical pressure range obtained from conical shock analysis for 0° agrees with the experimentally derived pressure range for the model, and the outliers are attributed to errors in image registration. This study presents preliminary pressure measurements that pave the way for obtaining time-resolved global PSP measurements to train and validate aerothermodynamic machine learning models.

Benefits and trade-offs of optimizing global land use for food, water, and carbon

Current large-scale patterns of land use reflect history, local traditions, and production costs, much more so than they reflect biophysical potential or global supply and demand for food and freshwater, or-more recently-climate change mitigation. We quantified alternative land-use allocations that consider trade-offs for these demands by combining a dynamic vegetation model and an optimization algorithm to determine Pareto-optimal land-use allocations under changing climate conditions in 2090-2099 and alternatively in 2033-2042. These form the outer bounds of the option space for global land-use transformation. Results show a potential to increase all three indicators (+83% in crop production, +8% in available runoff, and +3% in carbon storage globally) compared to the current land-use configuration, with clear land-use priority areas: Tropical and boreal forests were preserved, crops were produced in temperate regions, and pastures were preferentially allocated in semiarid grasslands and savannas. Transformations toward optimal land-use patterns would imply extensive reconfigurations and changes in land management, but the required annual land-use changes were nevertheless of similar magnitude as those suggested by established land-use change scenarios. The optimization results clearly show that large benefits could be achieved when land use is reconsidered under a "global supply" perspective with a regional focus that differs across the world's regions in order to achieve the supply of key ecosystem services under the emerging global pressures.

Challenges and Opportunities of Altasia: A National Benchmarking Assessment

As global pressures mount to diversify supply chain strategies beyond China, the concept of “Altasia” has emerged, encompassing 14 alternative countries. This study offers a comprehensive framework describing the historical context, driving factors, and theoretical underpinnings motivating the global shift away from China. Our research model delineates the strategic pathways employed by multinational corporations to navigate the decoupling process, particularly in identifying alternative manufacturing hubs across the Altasia region. This article critically examines the multifaceted challenges and opportunities inherent in Altasia as a collective entity comprising these 14 alternative countries. Furthermore, it explores the transformative implications of this paradigm shift on the broader global supply chain ecosystem. In conclusion, we highlight the forward-looking significance of these findings, shedding light on avenues for future research endeavors in this evolving landscape.

Machine Learning-Based Calibrated Model for Forecast Vienna Mapping Function 3 Zenith Wet Delay

An accurate estimation of zenith wet delay (ZWD) is crucial for global navigation satellite system (GNSS) positioning and GNSS-based precipitable water vapor (PWV) inversion. The forecast Vienna Mapping Function 3 (VMF3-FC) is a forecast product provided by the Vienna Mapping Functions (VMF) data server based on the European Centre for Medium-Range Weather Forecasts (ECMWF)-based numerical weather prediction (NWP) model. The VMF3-FC can provide ZWD at any time and for any location worldwide; however, it has an uneven accuracy distribution and fails to match the application requirements in certain areas. To address this issue, in this study, a calibrated model for VMF3-FC ZWD, named the XZWD model, was developed by utilizing observation data from 492 radiosonde sites globally from 2019–2021 and the eXtreme Gradient Boosting (XGBoost) algorithm. The performance of the XZWD model was validated using 2022 observation data from the 492 radiosonde sites. The XZWD model yields a mean bias of −0.03 cm and a root-mean-square error (RMSE) of 1.64 cm. The XZWD model outperforms the global pressure and temperature 3 (GPT3) model, reducing the bias and RMSE by 94.64% and 58.90%, respectively. Meanwhile, the XZWD model outperforms VMF3-FC, with a reduction of 92.68% and 6.29% in bias and RMSE, respectively. Furthermore, the XZWD model reduces the impact of ZWD accuracy by latitude, height, and seasonal variations more effectively than the GPT3 model and VMF3-FC. Therefore, the XZWD model yields higher stability and accuracy in global ZWD forecasting.

Ecological gradients in a marine cave revisited 26 years after

Marine caves are unique and vulnerable habitats threatened by multiple global and local pressures. Changes in the sessile epibenthic community of the Grotta Azzurra of Capo Palinuro (Salerno, Italy) during the last 26 years have been evaluated using growth forms and trophic guilds as non-taxonomic descriptors, informative of the structure and the functioning of the cave ecosystem, respectively. Photographic samples were collected in 1992 and 2018 to investigate the stability of the ecosystem response to the three main environmental gradients occurring inside the cave: i) confinement, ii) depth, and iii) light. Benthic communities were well spatially distributed along the three gradients inside the cave according to both the morphology and the feeding strategy of organisms, although the zonation was less marked considering trophic guilds. Gradients persisted and zones remained distinct through time, notwithstanding significant changes in community composition. The trophic organization was preserved throughout the cave, but significant changes in the spatial organization of benthic assemblages were widely observed, mainly due to 3-dimensional growth forms replaced by 2-dimensional (i.e., encrusting) growth forms and by increased sedimentation, thus causing the structural homogenization of the cave community. The outermost and the deepest sectors of the cave experienced higher changes compared to the most confined, blind-ended, sector and to the shallowest depths, which resulted comparatively more stable. From a functional point of view, filter feeders always dominated the communities (even considering their shift from erect to encrusting morphologies) and the few observed changes were due to the reduction of photophilic autotrophs and active ciliate without lophophore and the increase of mixotrophic sponges. As local human pressures remained low through the period considered, the changes observed are likely to be mainly due to global warming, which caused increased sea surface water temperatures and repeated summer heat waves (reported in 1994, 2003, 2008, 2012, and 2015). Regular monitoring programs on marine caves should be promoted to create historical series of data precious to better understand magnitude and pattern of change in the long-term evolution, and to estimate the recovery time of such priority habitats.

Editorial: water and environmental solutions for adaptation to global change pressures in developing countries

Editorial: water and environmental solutions for adaptation to global change pressures in developing countries

Расширение диапазона использования условного наклонения в современном испанском языке на примере бизнес-ситуаций

<p>This paper aims to comprehensively analyze the range of use for the conditional tense in the modern Spanish language in the context of the business environment. In the last few decades, its use spectrum has widened significantly, which is visible in expanding into the Present, Past and Future areas. This process is also apparent in different language registers: in colloquial speech and journalism and in the business sector. Based on theory and practical experience, the author analyses the conditional tense as a simple tense with great potential as a form of communication in business and mass media. We found that in some cases, the conditional tense could be substituted by other present or subjunctive tenses. That change shows us the tendency to prioritize simple tenses shaped by globalization and migratory pressures. This perspective may be interesting and valuable for language professors, businesspeople, and Spanish students in the light of the negotiation planning as well as interview and exam preparation, as the research can inspire them to use these speech models in their daily lives and business environment, bringing them closer to spontaneous fluent speaking.</p>

Social reproduction in crisis: Gendered labour regimes in agro‐export sectors in Ecuador and Chile

AbstractThe pandemic lays bare the centrality of social reproduction in upholding global commodity networks. Capitalism's reliance on gendered and racialized systems of social reproduction has deepened structural contradictions and socio‐economic divides across agro‐export sectors and agrarian communities. We analyse how COVID‐19 policies and responses in Ecuador and Chile are reshaping systems of social and labour protection in feminized agro‐export sectors. We integrate labour regime and gender regime frameworks, showing how they are (1) co‐constituted via global forces, national policies, institutional pressures and local practices; (2) intertwined in neoliberal and social‐democratic development models; and (3) forged through control, consent and resistance. We analyse national legal frameworks and policy responses to COVID‐19, as well as industry, union and worker reactions, illustrating how ‘neutral’ policies have gendered outcomes, (re)creating false binaries between production and reproduction and paid and unpaid work. We find that the pandemic has reshaped gendered labour regimes in agro‐exports: in Ecuador, undermining the fragile commitment to a social‐democratic gendered labour regime and in Chile, strengthening social‐democratic supports and promises of a more equitable gendered labour regime. In both cases, states and firms have neglected to include social reproduction in the ‘costs’ of development, thus threatening national development models grounded in the exploitation of cheap female labour in agro‐export sectors.

The adoption of the green label by SMEs in the hotel sector: a leverage for reassuring their customers

PurposeIn the era of new technological revolution, seeking to survive and guarantee business sustainability in their digital internationalization, enterprises choose to become environmentally oriented. The need for new green business models has become evident in recent years, and enterprises offer green services in creative and eco-friendly ways. However, does the display of a green label on hotels' websites really promote the eco-conscious tourists' online booking intention? This study aims to examine the impact of the perceived label on the online sustainable hotel booking intention of the eco-conscious tourists, using the foundations of signal theory.Design/methodology/approachThis study adopted a structural equation model to integrate several constructs with a sample of 349 validated responses.FindingsThe empirical results highlight, the importance of the green label perception on the eco-conscious tourists' booking intention of online sustainable hotel and the role that green trust and green perceived risk play as a mediating variable between the perception of the exposed label and the booking intention. Indeed, when booking a sustainable hotel online, the tourists may be sensitive to the exposure of a green label. Therefore, this signal decreases the perceived risk of unsustainability and ultimately increases the trust in hotel's sustainability.Research limitations/implicationsThe first limitation is related to the sample employed in this study. Given that most of the participants were residents of France, the results of this study may not be generalized to the entire population. Secondly, a range of other factors can affect the eco-conscious tourists' intentions to book online a hotel with green label, such as their attitude, social media influence, tourists' satisfaction, etc. Indeed, other variables and/or signals could be adopted to study online booking intention in the pandemic era.Practical implicationsIn light of these results, theoretical and managerial implications are discussed. The findings make an important contribution to SMEs sustainability and internationalization by exploring new ties. This study considers how SMEs and specifically hotels start following green practices (e.g. adoption of an eco-label) relevant to their international environment where they operate and in response to global pressures. SMEs can survive better in the highly competitive global environment where they need to employ more green practices, however, managers should consider how green trust and green perceived risk can affect customer behavior. It also adds to the existing literature by dealing with customer perceptions about the green label of sustainable hotels and its subsequent effect on booking intention.Originality/valueThis study had shown the importance of the display of green label on the eco-conscious tourist's online booking intention.

Book Review: The Politics of English Language Education and Social Inequality

Review of the book "The Politics of English Language Education and Social Inequality: Global Pressures, National Priorities and Schooling in India".