The pre-salt reservoirs play a significant role in the current Brazilian ultradeep water offshore scenario. Their importance is expected to increase soon. The fluids are transported through horizontal, inclined, and vertical wells of several kilometers, and due to the environmental conditions at the reservoir, dense-gas/liquid flow occurs in the pipelines. However, the literature lacks experimental data for gas-liquid flow with densities of the same order of magnitude, which affects the mechanistic model's accuracy for flow patterns, pressure gradients, and holdup predictions. To improve the understanding of that specific two-phase flow, an experimental apparatus was built, and an experimental study was carried out using sulfur hexafluoride (100 kg/m3) and mineral oil (850 kg/m3) at medium pressures. A density ratio lower than 10 was obtained for steady-state horizontal flow in a 50.8-mm-i.d. stainless-steel pipe, and flow patterns, pressure gradient, and holdup were measured. The experimental results show the effect of the low-density ratio on the stratified to non-stratified flow-pattern transition and the occurrence of the dual-continuous flow pattern at high mixture superficial velocity. Moreover, the pressure gradient and holdup data were compared with the results of a commercial multiphase flow simulator, showing good agreement.