Abstract Background Parkinson’s Disease (PD) is a progressive, complex neurodegenerative disease characterised by both motor and non-motor symptoms. PD medications are time sensitive, and their correct prescription and administration are crucial in optimal management strategies. Previous work presented at the Irish Gerontological Society showed a lack of knowledge regarding PD and its medications among healthcare staff in a level four hospital. Methods Data were collected from a retrospective chart analysis of PD admissions in 2019. 115 admissions coded PD were identified from HIPE data. Subsequently, 10 patients were randomly selected from medical, surgical, and orthopaedic admissions respectively (39 admissions). Patients were excluded if they were not on PD-specific medications or if their drug Kardex was not available. 28 patient Kardex’s were reviewed. Data was collected using a predetermined spreadsheet and analysed using Microsoft Excel. Results 100% of patients were on levodopa medication. 86% of patients did not receive their appropriate PD medications in the Emergency department. 21% had errors in medication prescription (omitted drug [n = 4, 14%], incorrect timings [n = 2, 7%]) on admission. 75% missed at least one dose of levodopa. 83 doses of levodopa were missed across the 28 admissions. 40% were because the patient was nil by mouth (NPO), while 21% had no reason documented. 64% of patients had doses of levodopa delayed by more than 1 hour, with over 80% of these in the perioperative period. 5 patients (18%) received antidopaminergic drugs. Conclusion This review highlighted multiple shortcomings in PD medication management during acute admissions. We introduced hospital guidelines for the management of patients with PD while NPO. This guideline includes information on alternatives to oral route, advice regarding the perioperative period, and medications to avoid. It has been approved by the Medications and Therapeutics committee and will be introduced with education sessions at the changeover. We will reaudit practices after 6 months.