The aim of this prospective clinical study is to evaluate the effects of laceback and Uprighter techniques on maxillary canine retraction using digital models and panoramic radiographs and to compare the results.Sixteen patients (10 females, 6 males) with an average chronological age of 16.24±2.99 years, requiring fixed orthodontic treatment with upper canines located in a high vestibular position and the need for bilateral first premolar extraction, were included in this study. 0.018-inch Roth brackets were used in the patients. In this split-mouth design study, while laceback was used on one side, Uprighter was used on the other side. Tooth movements were measured on three-dimensional models and panoramic radiographs obtained at the beginning of treatment (T0), 2 months later (T1), and 3.5 months later (T2). Two-way analysis of variance was applied for the comparison of differences between the groups in repeated measurements.The difference between groups was found to be statistically significant in terms of canine distalization, canine rotation, and molar angulation amounts. There was no statistically significant difference in the other parameters.Both uprighter and laceback techniques can be applied in maxillary canine cases located in the high vestibule. When Uprighter is used, the canine is distalized much more. However, it should be noted that while more molar tipping may occur when laceback is used, more canine distopalatal rotation may occur when uprighter is used.