Levels In Pregnant Women Research Articles

Diagnostic and Prognostic Value of Deregulated Long Non-Coding RNA Plasmacytoma Variant Translocation 1 in Patients with Gestational Hypertension.

This study aimed to investigate the serum plasmacytoma variant translocation 1 (PVT1) level in pregnant women with gestational hypertension and pre-eclampsia and its diagnostic value for diseases and its influence on pregnancy outcome. Serum PVT1 levels in 72 pregnant women with gestational hypertension, 72 pregnant women with pre-eclampsia and 71 healthy pregnant women were evaluated by RT-qPCR, and the diagnostic significance of PVT1 for gestational hypertension was verified by receiver operator characteristic (ROC) curve. The correlation between PVT1 and clinical indicators were evaluated by Pearson correlation coefficient method. Logistic regression analysis evaluated the influencing factors in the development process of gestational hypertension to pre-eclampsia. The effect of PVT1 level on pregnancy outcome was evaluated by prognostic analysis. Results showed that PVT1 level was down-regulated in gestational hypertension group compared with healthy control group, whereas PVT1 level was down-regulated more significantly in pre-eclampsia group than in gestational hypertension group. ROC curve showed that PVT1 had high diagnostic accuracy for gestational hypertension. Pearson correlation coefficient and multiple linear regression analysis showed that PVT1 was correlated with systolic blood pressure, diastolic blood pressure, interleukin (IL)-6 and tumor necrosis factor-α. Logistic regression analysis revealed that IL-6 and PVT1 were the influencing factors of gestational hypertension to pre-eclampsia transition. Moreover, prognostic analysis manifested that the incidence of fetal growth restriction in low PVT1 expression group was significantly higher than that in high PVT1 expression group. The expression level of PVT1 has a high diagnostic accuracy for gestational hypertension, and the low PVT1 expression group is more prone to fetal growth restriction.

The impact of vitamin D deficiency on gestational COVID-19 infection

Background: A worldwide pandemic infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2020 caused an outbreak of the disease called COVID-19 infection. Multiple researchers investigated the effect of serum Vitamin D levels in preventing and treating infectious respiratory syndromes. Vitamin D is a steroid hormone and fat-soluble vitamin which helps preserve a strong immune system and is frequently taken as supplements for the prevention of viral and bacterial illnesses. The serum Vitamin D levels in pregnant women have led to discussions on the severity of the clinical outcomes and its possible role in preventing a COVID-19 infection by treating Vitamin D deficiency with supplements. The purpose of this study is to describe the most recent studies on the impact of vitamin D levels on pregnant women with COVID-19 infection. Methods: This is a narrative literature review in which PubMed, Medline, ScienceDirect, Cochrane and Google Scholar database were used to select the most relevant research published in English before December 2022 and available to the authors. Results and Conclusion: Although lower serum vitamin D levels are associated with a higher chance of contracting a serious disease caused by several respiratory viruses like SARS-CoV-2, they are not associated with a higher possibility of COVID-19 occurring in expecting women. Key words: COVID-19, SARS-CoV-2, Vitamin D, Vitamin D deficiency, pregnant women

Gestational TSH Levels and Their Association with Obstetric and Neonatal Outcomes in Lebanon: A National Observational Retrospective Study

Objectives: Gestational hypothyroidism is associated with obstetric complications and disturbances in the offspring development; however, it remains easy to treat. The objective of the study was to describe thyroid-stimulating hormone (TSH) levels in pregnant women and analyze their association with pregnancy course and outcome. Design: This national, observational, retrospective study analyzed data on Lebanese pregnant women visiting their obstetrician as part of their routine follow up. Participants, Setting and Methods: Enrolled subjects were all pregnant women who visited the obstetrics clinic from 01 September 2017 until 31 August 2018, as part of their routine follow up and have a TSH level record. In 2020, during their routine follow-up visit, the participants signed an informed consent to allow the investigator to access the data retrospectively and enter them into his database. Relevant participant characteristics and outcome data were collected from clinic files of the private clinic of Dr Abi Tayeh, at the Department of Obstetrics and Gynecology, H?tel-Dieu de France University Hospital, Beirut, Lebanon. Results: A total of 419 women were enrolled, 11.5% of them reported at least one comorbidity prior to pregnancy, most often the antiphospholipid syndrome, followed by thrombophilia and hypothyroidism. At least one complication was reported for 18.4% of participants. Around 87.6% of participants delivered a full-term baby with normal birth weight for most. The average TSH value for all participants was within the normal range at all time-points. Highest TSH values were recorded during the first trimester. As treatment was immediately initiated in women with abnormal TSH levels, no correlation was observed between TSH levels and pregnancy outcomes or pregnancy complications at any time-point. Conclusions: This study highlights satisfactory routine practice in the management of thyroid disorders in pregnancy and underscores the need for routine TSH screening for all pregnant women.

Reference Intervals of Thyroid Hormones During Pregnancy Established by Three Statistical Methods.

Monitoring the thyroid hormones during pregnancy is of great importance for fetal growth and development. Throughout the whole pregnancy, there is constant fluctuation in the thyroid hormone reference intervals (RIs). The purpose of this study is to determine method- and trimester-specific RIs for thyroid-stimulating hormone, free thyroxine, and free triiodothyronine in pregnant women in China. In this study, 2,167 women with normal pregnancies (first trimester, n = 299; second trimester, n = 1,032; third trimester, n = 836) and 4,231 healthy nonpregnant women subjects were recruited. Serum thyroid-stimulating hormone (TSH), free thyroxine (fT4), and free triiodothyronine (fT3) concentrations were measured using electrochemiluminescence immunoassays in Abbott Alinity i analyzer. Following the exclusion of outliers, the RIs were determined using three statistical techniques: the non-parametric method, the Hoffmann method, and the Q-Q plot method. Pregnant women's levels of these three thyroid hormones differ markedly from those of healthy non-pregnant women. In addition, the concentrations of these three hormones change considerably over the course of the three phases of pregnancy. The Q-Q plot method offered more comparable RIs with the non-parametric method in healthy non-pregnant women than the Hoffmann method. Three statistical techniques were used to construct the trimester-specific RIs of thyroid hormones in pregnant women, and there was little difference between them all. The RIs by the non-parametric and Q-Q plot methods indicated closer RIs, and the RIs by the Hoffmann approach were higher and wider than those by the other two methods. For thyroid hormones, trimester-specific RIs are required. The RIs determined by non-parametric and Q⁃Q plot indirect calculation could be used as the alternative method.

PEMERIKSAAN KADAR HAEMOGLOBIN PADA IBU HAMIL DI LABORATORIUM PRODI KEBIDANAN AMBON POLTEKKES KEMENKES MALUKU

Policies related to pregnancy are the integrated Antenatal Care (ANC) program for every pregnant woman, namely the 14T examination in which there is an examination of hemoglobin levels. Checking hemoglobin (Hb) levels is carried out in the laboratory to determine red blood cell levels in pregnant women to ensure Hb levels are above 11 g/dL. If the Hb level is below 11 g/dL, then the pregnant woman has anemia which can disrupt the growth and development of the fetus and can cause a risk of bleeding in the mother during delivery. The aim of this study was to determine the hemoglobin level of pregnant women. The type of research used is observational research with a prospective descriptive nature with a cross-sectional research design. The subjects of this study were third trimester pregnant women who had an examination at the Ambon Midwifery Study Program Laboratory. The result showed that 60% of the 20 respondents (12 pregnant women) had normal Hb levels, while 8 pregnant women (40%) had abnormal Hb levels. There are more pregnant women with Hb levels ≥ 11.0 g/dL than pregnant women with Hb levels < 11.0 g/dL. It is recommended that pregnant women carry out routine pregnancy checks at the Public Health Center and take Fe tablets as recommended and consume nutritious food.

EFEKTIVITAS SEDUHAN BUNGA ROSELLA TERHADAP KADAR HAEMOGLOBIN PADA IBU HAMIL DI PUSKESMAS SUKAINDAH KABUPATEN BEKASI PERIODE MEI - JUNI TAHUN 2021

Anemia is one of the factors of maternal death. The government has tried to prevent it by giving Fe tablets during pregnancy. Fe tablets can increase hemoglobin levels, and it is more effective if you consume the Fe tablets by drinking rosella flower steeping. Sukaindah Health Center, Sukakarya District, Bekasi Regency, it was found that the incidence of anemia in pregnant women was quite high. The purpose of the study was to knowing the effectiveness of steeping rosella flowers on increasing hemoglobin levels in pregnant women at the Sukaindah Health Center, Sukakarya District, Bekasi Regency in 2021. Methods: quasi-experimental research using a pre-test-post-test control group design. The sample in this study amounted to 42 respondents with total sampling technique. The data were analyzed using the Independent T-Test. Result: univariate analysis the difference in the average administration of rosella flower steeping and Fe tablets was 0.733 and the difference in the average administration of Fe tablets was 0.262. The results of the bivariate analysis showed the effectiveness of steeping rosella flowers on increasing hemoglobin levels in pregnant women with a significance level of 0.000. The conclusion provision of rosella flower infusion is effective in increasing hemoglobin levels of anemic pregnant women. Suggestions for pregnant women are expected to be diligent in consuming foods that contain iron and be obedient in consuming tablets along with steeping rosella flowers before going to bed in order to increase Hb levels in the mother's blood.

Effect of consuming ambon banana on increasing hemoglobin levels in pregnant women

The results of the 2018 Basic Health Research stated that in Indonesia 48.9% of pregnant women had anemia. The aim of the study was to determine the effect of consumption of Ambon bananas on increasing Hb levels in pregnant women. This research method uses a quantitative method with the Pre Experiments one group pretest-posttest design. The research sample consisted of 10 respondents using a purposive sampling technique. Based on the univariate results, the highest percentage before administration of Ambon bananas was pregnant women with a hemoglobin level of 9 g/dL in 5 people (50%), a hemoglobin level of 10-11 g/dL in 3 people (30%), a hemoglobin level of 10-11 g/dL dL in 3 persons (30%). level of 8 g/dL in 2 people. people (20%). After giving Ambon bananas to pregnant women who had a hemoglobin level of 12 g/dL in 3 people (30%), a hemoglobin level of 11 g/dL in 5 people (50%), a hemoglobin level of 10 g/dL in 2 people (20%) . Statistical test results obtained P Value 0.004 <0.005 where there was an effect between hemoglobin levels before and after administration of Ambon bananas with a P Value of 0.004 <0.005

Relationship between Sera Vitamin D, Calcium, and Magnesium Levels in Pregnant Women with and without Postpartum Depression

Postpartum depression (PPD) is a significant mental health case after childbirth, distinguished by behavioral changes and emotional disturbance. PPD is a significant public issue estimated to affect 10–15% of women worldwide. The study's objective was to investigate whether low sera concentrations of vitamin D, calcium, and magnesium during the third trimester of pregnancy are associated with PPD. The study population included eighty pregnant women between the ages of 25 to 35 years. They were divided into two groups (control and depressed group). Simple samples technique collecting was used for serum collecting from the two groups. When the blood samples were taken, vitamin D level was determined using an ELISA device. Calcium and magnesium were measured by using the spectrophotometric method. A health questionnaire structure was used for screening depression after birth. After measuring pregnancy serum concentrations of vitamin D of (40) pregnant control and (40) pregnant with PPD, we found that there was no significant relationship between vitamin D concentrations and risk of PPD (p= 0.6497). Statistical analysis indicated the significant differences (p= 0.0003) between sera calcium levels of the control group as compared with the depressed group. Significant differences (p= 0.0005) in magnesium levels between the two groups were observed. Our study detected that vitamin D concentrations in the serum of women during their last trimester of pregnancy had no statistical link with their risk of PPD. Whereas direct associated with calcium and magnesium deficiency in the third trimester of pregnancy and the incidence of PPD were reported.

Gambaran Kadar Hemoglobin Dan Protein Urin Pada Ibu Hamil

Backgrounds of hemoglobin is a metalloprotein in red blood cells that functions as an oxygen booster from the lungs to the rest of the body. To maintain hemoglobin levels in the body, especially in pregnant women, it is necessary to have adequate intake of nutrients, namely iron. If the intake of iron in pregnant women is less, it will increase the risk of anemia. Anemia is a condition or condition that causes low levels of hemoglobin (Hb). Albuminuria or proteinuria is a condition in which urine or urine contains an abnormal amount of albumin. Throughout pregnancy, pregnant women are usually advised to take a urine test. One of the focuses of the urine test is to determine urine protein levels in pregnant women. In pregnant women, there is a phase where urine protein levels increase, namely, lack of fluids, exposure to cold and extreme weather, new strenuous activities, and emotional stress also often causes urine protein levels in pregnant women to increase, and impaired kidney function. or urinary tract infection. The method we used in this research is descriptive research method to describe the levels of hemoglobin (Hb) and urine protein in pregnant women at the Ubud 1 Public Health Center, Gianyar-Bali. With the sampling technique using the probability sampling method, with a simple random sampling technique. The results of 41 respondents, that pregnant women who have normal Hb levels (≥ 11 g/dL) at Puskesmas Ubud 1 were found to be more than pregnant women who have low Hb levels ( 11 g/dL). And from the total sample, as well as 2 pregnant women from the urine protein level examination data were positive. The conclusion after averaging the Hb and urine protein levels of pregnant women at the ubud 1 health center that it can be said that the health condition of pregnant women is quite good, but there are still some respondents who show results that are not in accordance with normal limits, therefore it is important to maintain health and pattern healthy living.Keywords: hemoglobin, urine protein, pregnant women

The Description Of Hemoglobin Levels In Pregnant Woman In Work Area Of Puskesmas Tampaksiring I

Background Anemia in pregnancy is a major health problem in developing countries with a high level of morbidity in pregnant women. The incidence of anemia in pregnancy is a condition of pregnant women with hemoglobin (Hb) levels 11 g/dL in the first and third trimesters, meanwhile in the second trimester Hb levels 10.5 g/dL. The purpose of this study was to determine the description of hemoglobin levels in pregnant women in the work area of Puskesmas Tampaksiring I. The research method used a descriptive type of research conducted in January-May 2022 with a total of 38 respondents obtained by random sampling technique. Hemoglobin levels were measured by the Point Of Care Testing (POCT) method. The results showed that 38 respondents (42.1%) had low hemoglobin levels, (55.3%) had normal hemoglobin levels, and (2.6%) had high hemoglobin levels. Low hemoglobin levels were mostly found in pregnant women who were in the range of 18-25 years, with less knowledge and were in a risky gestational age (Trimester I and III) and did not comply in taking blood-boosting tablets (TTD). The conclusion of this study is that most pregnant women have normal hemoglobin levels with a percentage of 55.3%.

GAMBARAN HEMOGLOBIN IBU HAMIL DI UPTD PUSKESMAS III DINAS KESEHATANKECAMATAN DENPASAR UTARA TAHUN 2022

Background: Hemoglobin deficiency in pregnant women is one of the health issues that can occur during the pregnancy. Anemia is more common in pregnant women because they require more oxygen, which causes an increase in erythropoietin production. The risk of anemia is connected to hemoglobin levels in pregnant women, with hemoglobin levels of less than 11 g/dl being classified low. Premature labor, miscarriage, extended labor, uterine atony, hemorrhage, and shock are all risks of anemia during pregnancy. Methods: The study used a descriptive design with a sample population of 34 pregnant women. Results: Hemoglobin levels in 22 pregnant women (64.7%) were relatively low, with the majority of them coming onto an age category of not at risk 18 people (81.8%), second trimester age 9 pregnant women (40.9%), pregnancy distance 13 pregnant women (59.1%), and parity 16 pregnant women (72.7%). Conclusion: The majority of pregnant women at UPTD PUSKESMAS III North Denpasar District Health Office have low hemoglobin levels.

The Effect of Hydrotherapy and Progressive Muscle Relaxation (PMR) on Cortisol Levels in Primigravida Pregnant Women

This study aims to measure cortisol levels in pregnant women who have intervened with Hydrotherapy and Progressive Muscle Relaxation to reduce anxiety in pregnant women in facing labor. This type of research uses quantitative with a quasi-experimental design, and a pretest-posttest approach with a control group [10]. The sampling technique used was purposive sampling so that a total sample of 30 respondents was obtained. Analysis of the data collected in the study was processed analytically with the T-Paired test and the Independent Test. The results of this study showed that the hydrotherapy and Progressive Muscle Relaxation group with Paired T test results worth P Value 0.017 = 0.05, meaning that there is no effect of hydrotherapy and Progressive Muscle Relaxation on cortisol levels. Hydrotherapy and Progressive Muscle Relaxation therapy are effective in reducing anxiety levels and cortisol levels in primigravida pregnant women in the face of childbirth.

Maternal Inflammatory Biomarkers during Pregnancy and Early Life Neurodevelopment in Offspring: Results from the VDAART Study

Maternal infection and stress during the prenatal period have been associated with adverse neurodevelopmental outcomes in offspring, suggesting that biomarkers of increased inflammation in the mothers may associate with poorer developmental outcomes. In 491 mother-child pairs from the Vitamin D Antenatal Asthma Reduction Trial (VDAART), we investigated the association between maternal levels of two inflammatory biomarkers; interleukin-8 (IL-8) and C-Reactive Protein (CRP) during early (10-18 wks) and late (32-38 wks) pregnancy with offspring scores in the five domains of the Ages and Stages Questionnaire, a validated screening tool for assessing early life development. We identified a robust association between early pregnancy IL-8 levels and decreased fine-motor (β: -0.919, 95%CI: -1.425, -0.414, p = 3.9 × 10-4) and problem-solving skills at age two (β: -1.221, 95%CI: -1.904, -0.414, p = 4.9 × 10-4). Associations between IL-8 with other domains of development and those for CRP did not survive correction for multiple testing. Similarly, while there was some evidence that the detrimental effects of early pregnancy IL-8 were strongest in boys and in those who were not breastfed, these interactions were not robust to correction for multiple testing. However, further research is required to determine if other maternal inflammatory biomarkers associate with offspring neurodevelopment and work should continue to focus on the management of factors leading to increases in IL-8 levels in pregnant women.

Maternal Serum Cripto-1 Levels in Pregnancies Complicated with Placenta Previa and Placenta Accreta Spectrum (PAS).

To examine maternal serum Cripto-1 levels in placenta accreta spectrum (PAS) pregnancies and compare them with placenta previa (PP) cases and healthy pregnancies. A prospective case-control study. Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey, from April to September 2021. Sixty singleton pregnant patients with PP complicated with PAS were enrolled, 45 singleton pregnant women with a diagnosis of PP without PAS, and 48 healthy uncomplicated gestational age-matched singleton pregnant women. Cripto-1 levels were determined and evaluated. The median maternal serum concentrations of Cripto-1 were greater in pregnant women with PAS (3.11 ng/mL) than in the PP (2.52 ng/mL) and the control groups (2.01 ng/mL, p<0.001). Based on the Youden index, a 2.557 ng/mL cut-off value of maternal serum Cripto-1 level had a 76.7% sensitivity and 72.1% specificity to diagnose pregnancies complicated with PAS. A negative and statistically significant linear relationship was found between maternal serum Cripto-1 concentration and the gestational week at birth (r= -0.325, p<0.001). A positive and statistically significant linear relationship was found between maternal serum concentrations of Cripto-1 and maternal length of hospital stay after birth (r= 0.320, p<0.001). Serum Cripto-1 levels were significantly increased levels in pregnant women suffering from PAS than in pregnant women with PP and uncomplicated healthy pregnancies. Higher expression of Cripto-1 might be a crucial factor in the pathogenesis of PAS. Abnormal placental implantation, placenta accreta spectrum, Cripto-1, Placenta previa.

Current Status of Therapeutic Drug Monitoring in Mental Health Treatment: A Review.

Therapeutic drug monitoring (TDM) receives growing interest in different psychiatric clinical settings (emergency, inpatient, and outpatient services). Despite its usefulness, TDM remains underemployed in mental health. This is partly due to the need for evidence about the relationship between drug serum concentration and efficacy and tolerability, both in the general population and even more in subpopulations with atypical pharmacokinetics. This work aims at reviewing the scientific literature published after 2017, when the most recent guidelines about the use of TDM in mental health were written. We found 164 pertinent records that we included in the review. Some promising studies highlighted the possibility of correlating early drug serum concentration and clinical efficacy and safety, especially for antipsychotics, potentially enabling clinicians to make decisions on early laboratory findings and not proceeding by trial and error. About populations with pharmacokinetic peculiarities, the latest studies confirmed very common alterations in drug blood levels in pregnant women, generally with a progressive decrease over pregnancy and a very relevant dose-adjusted concentration increase in the elderly. For adolescents also, several drugs result in having different dose-related concentration values compared to adults. These findings stress the recommendation to use TDM in these populations to ensure a safe and effective treatment. Moreover, the integration of TDM with pharmacogenetic analyses may allow clinicians to adopt precise treatments, addressing therapy on an individual pharmacometabolic basis. Mini-invasive TDM procedures that may be easily performed at home or in a point-of-care are very promising and may represent a turning point toward an extensive real-world TDM application. Although the highlighted recent evidence, research efforts have to be carried on: further studies, especially prospective and fixed-dose, are needed to replicate present findings and provide clearer knowledge on relationships between dose, serum concentration, and efficacy/safety.

Evaluation of Klotho gene expression and NGAL levels following acute kidney injury during pregnancy hypertensive disorders.

This study examined the relationship between hypertensive disorders and acute kidney injury (AKI) during pregnancy by evaluating Klotho (KL) gene expression and Neutrophil gelatinase-associated lipocalin (NGAL) levels in pregnant women. Pregnant women were divided into 3 groups: (1) Pregnancy related hypertensive disorders with AKI (PR-AKI) (9 cases), (2) hypertensive disorders pregnancy (HDP) (40 cases), and (3) normal pregnancy (30 cases). For each group, Klotho gene transcription levels in the blood, Klotho and NGAL proteins levels, Malondialdehyde (MDA) and superoxide dismutase (SOD) activity levels were measured in serum. Statistical comparisons were made among the three groups. Klotho/β-actin transcript levels and serum KL protein concentrations were significantly decreased in hypertensive disorder pregnancies with AKI complications. Serum NGAL protein levels were significantly increased in the hypertensive disorder pregnancies with AKI complications. Total serum Klotho protein was negatively correlated with creatinine, while serum NGAL was positively correlated with serum creatinine, urea nitrogen, uric acid, systolic blood pressure, diastolic blood pressure and 24h urine protein levels. Serum levels of MDA and SOD were significantly increased in the hypertensive disorder pregnancy with AKI and the overall MDA concentration was negatively correlated with Klotho protein concentration. Klotho protein was found to have a direct effect on creatinine, and a mediating effect of MDA was found. Decreased expression of Klotho protein in correlation with increased levels of oxidative stress are found during of AKI complications in pregnancy hypertensive disorders.

Giving green grass jelly for mda (malondialdehyde) level in pregnant women with hypertension

&lt;p align="center"&gt;&lt;strong&gt;&lt;em&gt; &lt;/em&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Background:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; Hypertension is a disease that often occurs during pregnancy. Many factors influence the occurrence of hypertension, one of which is oxidative stress. Oxidative stress has an important role in the pathogenesis of hypertension in pregnancy and may be a pathway that can lead to tissue damage. Oxidative stress can stimulate the release of cytokines, antiangiogenic, microparticles and other important molecules in hypertension. Oxidative stress is caused by an imbalance of prooxidants and antioxidants. So we need antioxidants that can suppress oxidative stress in pregnant women with hypertension. Green grass jelly contains alkaloids and flavonoids. Where flavonoids can act as antioxidants and anti-inflammatory. Flavonoids can reduce arterial stiffness making Reactive Oxygen Species (ROS) decrease so that fat peroxide decreases and is followed by decreased oxidative stress, then endothelial function will increase and vasodilation occurs. Malondialdehyde (MDA) is an aldehyde marker compound that is important to see lipid peroxidation and oxidative damage caused by Reactive Oxygen Species (ROS).&lt;/em&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Objectives:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; To prove that giving green grass jelly has an effect on reducing oxidative stress in pregnant women.&lt;/em&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Methods&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;: This study used a quasy experiment with a pretest and posttest control design. A sample of 30 was divided into 2 groups. The group with green grass jelly intervention was 15 people who were given green grass jelly as much as 150 grams per day for 14 days. The second group as many as 15 people as the control group.&lt;/em&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Results:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; The green grass jelly intervention group had a significant difference with p-value &amp;lt;0.05. For malondialdehyde results in the control group there was no change in p-value &amp;gt; 0.05. The mean decrease in malondialdehyde levels in the control group was 0.0560 nmol/ml while the average decrease in malondialdehyde in the intervention group was 1.3133 nmol/ml.&lt;/em&gt;&lt;/p&gt;&lt;strong&gt;&lt;em&gt;Conclusions:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; Green grass jelly is effective and significant for reducing malondialdehyde levels in pregnant women with mild hypertension.&lt;/em&gt;

Uric Acid Levels in Pregnant Women

Background: Preeclampsia in pregnant women can be detected by measuring uric acid levels in the blood. This can occur due to changes in the hemodynamic system and decreased glomerular filtration rate during pregnancy. Purposes: This study aims to determine the description of uric acid levels in pregnant women at Community Health Centers I, South Denpasar. Methods: This study uses a descriptive observational method from April to May 2022, with 31 respondents obtained by non-probability sampling technique. Uric acid levels were measured by the Point of Care Testing (POCT) method. Results: The results showed 23 pregnant women (74.2%) with normal uric acid levels and eight pregnant women (25.8%) with high uric acid levels. Conclusion: High uric acid levels are most suffered by pregnant women aged 30 years (16.1%), most commonly found in the third trimester of pregnancy (16.1%), most pregnant women with a body mass index (BMI) more and obesity (9.7%), and pregnant women with normal blood pressure (22.6%).

THE ASSOCIATION BETWEEN HB LEVELS AND PLACENTA PREVIA IN GRAVIDA PATIENTS

A placenta previa develops in the lower part of the uterus, covering the internal uterine ostium entirely or partially. The risk of maternal and infant mortality and morbidity rises as the placenta's inadequate vascularization expands to cover the entire birth canal. Hemoglobin (Hb) level is a biochemical indicator to determine the nutritional status of pregnant women, and reduced blood supply to the placenta can be caused by a lack of Hb levels in pregnant women. The purpose of this study was to determine the association between Hb level in gravida patients and the incidence of placenta previa at Sultan Agung Islamic Hospital, Semarang. This research was an observational analytic study with a cross-sectional design, which was conducted on 97 respondents who met the inclusion and exclusion criteria. The data was taken from the patient's medical record document from January 2017 - January 2018 at Sultan Agung Islamic Hospital. Analysis of the research data using the Chi-Square test. The findings revealed a significant correlation between Hb level and placenta previa incidence, low Hb levels (&lt;11 g/dl) could significantly increase the risk of placenta previa in gravida patients.

Manajemen Positif Coping Ibu Hamil Melalui Senam Hamil

A woman is said to be ready to get pregnant if she has gone through the process of achieving physical readiness, mental readiness, and economic readiness. Pregnant women are prone to experiencing psychological problems such as anxiety and depression which are closely related to the birthing process. Some pregnant women feel worried about the delivery process due to their previous experience of childbirth which was quite painful. This Community Service is carried out to help reduce maternal psychological problems during pregnancy by increasing positive individual coping through pregnancy exercise. This PKM is carried out using pregnant women's health interventions through counseling and pregnancy exercises. Pregnant women gain knowledge about stress management and know the techniques in pregnancy exercise. Through pregnancy exercise, it can reduce stress levels in pregnant women after covid 19.