The analysis of altimetric profiles in Antarctica and their evolution over the years is a sensitive topic for the scientific community since it helps understand the effects of climate change that the continent undergoes. Different geomatic techniques, including the GNSS technology, can be employed to obtain altimetric profiles. However, the GNSS differenced approaches, such as the Post Processing Kinematic, are hardly usable to define long profiles in Antarctica because of the low number of CORS stations. In these conditions, the Precise Point Positioning (PPP) approach is a valid alternative to avoid processing very long baselines. The aim of this article is to define a standard procedure for the processing of historical GPS data, thanks to the availability of a dataset from the International Trans-Antarctic Scientific Expedition, which took place between 1998 and 1999 (ITASE98-99). This expedition focused on mapping the Antarctic territory, subdividing it by nations of influence, using geophysical and geodetic technologies, including GPS. The altimetric profiles had already been calculated in 2002 by the Geomatics group of the University of Bologna using the Gipsy-OASIS II software. In this work, the new version of the JPL software, GipsyX, is used to apply the newly implemented models and reprocessed products. The calibration of the processing parameters leading to the final PPP solution is described in the paper, including details on the implementation of a post-processing filtering procedure. The average a posteriori elevation error is 4.6 cm, while 99% of them are within 27 cm. The comparison of the new results to both the previous processing and the REMA elevation model shown that about double the number of solutions are now available, meter-level elevation spikes have been avoided, and a half meter bias is now reduced to a few centimeters. Given the almost 15 years difference between the 1999.0 expedition epoch and the REMA reference epoch, the obtained results can be used to study accumulation/erosion effects on the Antarctica ice sheet.