This study investigated how a six-week training program involving aerobic exercise affected the lipid profile of women who were sedentary. Using the pre-test post-test model, 36 sedentary female volunteers aged 18-29 years participated in the study. After the participants had fasted overnight, healthcare professionals took blood samples from them both before and after the training program in a clinical setting. Measurements were taken of triglyceride, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and total cholesterol. The data obtained was subjected to a paired-samples test using the SPSS 22.0 statistical program to compare the values before and after training. Effect sizes (Cohen's d) were used to clarify the levels of comparison. Statistically significant differences were seen in blood lipid levels (triglycerides, HDL, LDL, and total cholesterol) between pre- and post-training assessments (p < 0.05). This study found that a six-week aerobic exercise program significantly increased HDL cholesterol levels by 15.8% (from 46.66 mg/dL to 54.05 mg/dL, p = 0.000) and decreased LDL cholesterol levels by 15.7% (from 96.72 mg/dL to 81.52 mg/dL, p = 0.000) in sedentary women. The study adds to the growing body of evidence suggesting that aerobic exercise programs, such as spinning, can significantly improve lipid profiles in sedentary women, potentially reducing their risk of cardiovascular disease. Future research should incorporate control groups to strengthen these findings.
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