The 38th general council of UNESCO presented the idea of ensuring inclusive and equal quality education and promoting lifelong learning for all. Since 1965, when Mr. Paul Lengrand introduced the concept of lifelong education, countries all over the world have unceasingly carried on some practices. Since 1990s, the construction of lifelong education system has been regarded as an important subject of education reform and development in China. However, on the whole, only the important measures to construct the lifelong education system has been heard so far, and few concrete practices has been seen. And the lifelong special education service system is even more a kind of that can not be reached.Special Education Promotion Plan (2014-2016) issued by the General Office of the State Council of the people’s Republic of China proposes to actively develop special education in non-compulsory education stages. From the perspective of lifelong learning for all, based on lifelong learning for disabled people and diversified needs of special students, lifelong special education practices, which lasted 15 years with three phases of action research has been carried out in Changning District of Shanghai. The government of Changning District has set up a substantive regional special education guidance center, established a multi-disciplinary resource platform for regional medical education, developed a regional off-campus lifelong special education curriculum, built a regional transition service mechanism for special students and constructed a life-long special education service system for disabled people from 0 to 3 years old and even the elderly. Three research conclusions have been drawn: based on a multi-disciplinary comprehensive service system, the construction of a life-long special education service system is a process of continuous progress towards an ideal state to remove obstacles in administrative system and mechanism.