Background: Coronavirus disease-2019 (COVID-19) was an emerging public health problem threatening the lives of over 2.4 million people globally. It was a great challenge for the management of all hospitals to respond to the coronavirus (COVID-19) outbreak at the early stage in the world. The most prominent problems were the arrangement of medical staff to diagnose and treat patients with COVID-19 and the allocation of medical protective equipment. The estimated basic reproductive number of the virus is significantly higher than many other infectious diseases, which can potentially result in the capacity of health facilities becoming overwhelmed, even in the countries with the most developed healthcare systems. Objective: The aim was to assess the level of nurses and practice regarding preventing complications of COVID-19 at Shaheed Ziaur Rahman Medical College Hospital, Bogura. Methodology: This descriptive cross-sectional study design was used, and a sample size of 110 that was a purposive sampling technique followed those who met the inclusion criteria to assess the nurses’ practice regarding the prevention of complications of COVID-19 at Shaheed Ziaur Rahman Medical College Hospital, Bogura. The study was conducted from July 2021 to December 2021. The instruments for data collection were a semi-structured questionnaire composed of three parts: Demographic variables, knowledge, and practice-based information on the prevention of COVID-19 complications. Results: The findings of the present study revealed that the demographic information the highest 40.91% were within ≤ 30 years of age, 77.27% were female, 90% were Muslim, 87.27% were married, and 46.36% were diploma in nursing. The average level of knowledge, 38.18%, was a high level of knowledge regarding the prevention of COVID-19, which may be due to their clinical experiences. Conclusion: Coronavirus disease 2019 (COVID-19) is a global public health threat, creating a pandemic worldwide. The preventive measures include strict quarantine and screening, as well as education to promote the use of masks and hand-washing practices. Nurses’ roles in the disease are an important cognitive key in public health regarding prevention and promotion.
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