Potential Risk Assessment Research Articles

Potential risk assessment: a model for quality evaluation in fluoroscopy-guided interventional procedures.

This study presented a model applied for potential risk assessment in an interventional radiology setting. The model of potential risk assessment (MARP) consisted of the creation of a scale of indicators ranging from 0 to 5. The radiation levels were categorized according to gender, kind of procedure, value of kerma air product (Pka), and accumulated radiation dose (mGy). The MARP model was applied in 121 institutions over 8 y. A total of 201656 patient radiation doses (Dose-area product and accumulated kerma) data were launched into the system over time, with an average of 22406 doses per year. In the context of the workers (cardiologists, radiographers, and nurses) monitored during the MARP application, 8007 cases (with an average of 890 per year) of occupational radiation doses were recorded. This study showed a strategy for quality evaluation in fluoroscopy using a model with a compulsory information system for monitoring safety.

Identifikasi Potensi Bahaya pada Stasiun Boiler Menggunakan Metode Hirarc di PT. Syaukath Agro

PT Syaukath Agro is a company operating in the Agribusiness Sector which is engaged in processing palm oil Fresh Fruit Bunches (FFB) into crude palm oil (CPO), Palm Kernel (PK) and shells. The palm oil processing system consists of several stages starting from receiving Fresh Fruit Bunches (FFB) to becoming palm oil or Crude Palm Oil (CPO). The palm oil processing process can be used in several stages carried out at each station. Based on interviews conducted, each station has a different level of risk of accidents, one of the stations that has a large risk of work accidents is the boiler station which is the heart of a palm oil factory where the steam boiler is the source of power and the source of the steam that will used to process palm oil. Boilers have potential dangers or risks when operated. The risks that often occur are falls, slips, burns, scalds, heat, noise, so it is very important to supervise and provide guidance regarding work safety. The size of the accident caused will certainly have a detrimental impact on the company. The severity of the accident can be determined through identification of potential dangers and risk assessment of all boiler operating activities at PT. Syaukath Agro. Based on the results of research conducted using the hirarc method, potential hazards found in boiler stations include: Unergonomic Working Attitudes, Noise Levels >84 dB with 8 Hours/Day Exposure, Working climate temperature (hot) 31°C on exposure >8 working hours/day, and oil buildup. Types of risk of work accidents at boiler stations consist of: Falls, injuries (slipping, slippery floors) Burns (in contact with hot objects around), Heat exhausting (Heat), Work accidents (fatigue ), hearing loss (noise), blisters (burns), health problems (muscles, bones), contact dermatitis (exposed to dangerous toxic radiation). Based on the results of risk control, it was found that the most appropriate type of control recommendation is administrative control and compliance with the use of personal protective equipment (PPE). Administration (Administration Control) is carried out by creating or providing a work system that can reduce the possibility of someone being exposed to potential dangers. The hierarchy of control of Personal Protective Equipment (PPE) is used to provide a boundary between exposure to the body and the potential danger received by the body.

Nanoparticles‐based double‐stranded RNA delivery as an antiviral agent in shrimp aquaculture

AbstractThe review encapsulates the comprehensive exploration of RNA interference technology's application in shrimp aquaculture, covering molecular intricacies, production methods, and practical applications. The emphasis is on exploring the stability and delivery of gene‐specific double‐stranded RNA, particularly through nanoencapsulation. This is because the susceptibility of dsRNA to degradation and limited cellular penetration, emphasising the need for effective delivery mechanisms. The review presents an in‐depth exploration of nanoparticles for the encapsulation and delivery of dsRNA, including virus‐like particles (VLPs), and non‐viral based nanoparticles such as liposomes, chitosan, and beta‐glucan. VLPs, derived from non‐infectious shrimp virus structures, exhibit biocompatibility and natural functionality, making them suitable carriers for dsRNA. The application of chitosan and its derivatives are explored for their efficacy in reducing viral infections in shrimp. Beta‐glucan particles are examined for their immunostimulant properties in shrimp aquaculture. The text emphasises the use of yeast‐based glucan particles for encapsulating dsRNA, showcasing their potential in preventing viral diseases in shrimp. The review introduces cautionary considerations for nanoparticle formulation, highlighting factors such as pH, organic solvents, metal ions, and environmental ribonuclease that can impact dsRNA stability during synthesis. In conclusion, the text discusses the potential economic worthiness and environmental risk assessment of dsRNA technology in shrimp aquaculture. While acknowledging successful applications in other environments, it underscores the need for regulatory approval and risk assessment for dsRNA‐based products in the aquaculture industry. The evaluation of dsRNA in real‐world shrimp farms is deemed necessary for commercial utilisation, taking into account income, expenses, safety, and environmental considerations.

Potential risk assessment and occurrence characteristic of heavy metals based on artificial neural network model along the Yangtze River Estuary, China.

Pollution from heavy metals in estuaries poses potential risks to the aquatic environment and public health. The complexity of the estuarine water environment limits the accurate understanding of its pollution prediction. Field observations were conducted at seven sampling sites along the Yangtze River Estuary (YRE) during summer, autumn, and winter 2021 to analyze the concentrations of seven heavy metals (As, Cd, Cr, Pb, Cu, Ni, Zn) in water and surface sediments. The order of heavy metal concentrations in water samples from highest to lowest was Zn > As > Cu > Ni > Cr > Pb > Cd, while that in surface sediments samples was Zn > Cr > As > Ni > Pb > Cu > Cd. Human health risk assessment of the heavy metals in water samples indicated a chronic and carcinogenic risk associated with As. The risks of heavy metals in surface sediments were evaluated using the geo-accumulation index (Igeo) and potential ecological risk index (RI). Among the seven heavy metals, As and Cd were highly polluted, with Cd being the main contributor to potential ecological risks. Principal component analysis (PCA) was employed to identify the sources of the different heavy metals, revealing that As originated primarily from anthropogenic emissions, while Cd was primarily from atmospheric deposition. To further analyze the influence of water quality indicators on heavy metal pollution, an artificial neural network (ANN) model was utilized. A modified model was proposed, incorporating biochemical parameters to predict the level of heavy metal pollution, achieving an accuracy of 95.1%. This accuracy was 22.5% higher than that of the traditional model and particularly effective in predicting the maximum 20% of values. Results in this paper highlight the pollution of As and Cd along the YRE, and the proposed model provides valuable information for estimating heavy metal pollution in estuarine water environments, facilitating pollution prevention efforts.

PFAS assessment in fish – Samples from Illinois waters

Per- and Polyfluoroalkyl substances (PFAS) have been widely used in various industries, including pesticide production, electroplating, packaging, paper making, and the manufacturing of water-resistant clothes. This study investigates the levels of PFAS in fish tissues collected from four target waterways (15 sampling points) in the northwestern part of Illinois during 2021–2022. To assess accumulation, concentrations of 17 PFAS compounds were evaluated in nine fish species to potentially inform on exposure risks to local sport fishing population via fish consumption. At least four PFAS (PFHxA, PFHxS, PFOS, and PFBS) were detected at each sampling site. The highest concentrations of PFAS were consistently found in samples from the Rock River, particularly in areas near urban and industrial activities. PFHxA emerged as the most accumulated PFAS in the year 2022, while PFBS and PFOS dominated in 2021. Channel Catfish exhibited the highest PFAS content across different fish species, indicating its bioaccumulation potential across the food chain. Elevated levels of PFOS were observed in nearly all fish, indicating the need for careful consideration of fish consumption. Additional bioaccumulation data in the future years is needed to shed light on the sources and PFAS accumulation potential in aquatic wildlife in relation to exposures for potential health risk assessment.

Potential Toxic Metal Concentration and Risk Assessment in Agricultural Soil and Lentil Crop (Lens culinaris Medik) in Dawunt Woreda, Northwest Wollo, Ethiopia.

Health implications for the population due to consuming contaminated crops have been a great concern worldwide. This study aimed to measure the levels of potential toxic elements in lentils and their growing soil in Dawunt Woreda, Ethiopia. Accordingly, 15 soil samples along with the lentil samples were collected to measure the level of potential toxic elements, including chromium (Cr), manganese (Mn), iron (Fe), lead (Pb), cadmium (Cd), copper (Cu), and cobalt (Co), by using an inductively coupled plasma optical emission spectrometer and for assessing the potential ecological and human health risk. The wet digestion method using aqua regia (HCl/HNO3 3 : 1) was employed for soil and lentil sample preparation. The mean concentrations of Fe, Mn, Co, Cu, Cd, Pb, and Cr in the lentil sample were 60.4, 9.68, 0.75, 5.7, 0.25, 0.9, and 1.15 mg/kg, respectively. In soil, the mean concentrations of Fe, Mn, Co, Cu, Cd, Pb, and Cr were 649, 19.9, 3.32, 40.0, 15.2, 1.83, and 69.1 mg/kg, respectively. All of the potential toxic metals in agricultural soil and lentil samples were found to be below the reference level set by the World Health Organization, except Cd, in the soil samples. Five single metal and three cumulative pollution index parameters were employed for the data and results showed that Fe, Cu, and Cr moderately pollute the soil and are highly contaminated by Cd. The cumulative pollution indices also confirmed that the extent of soil pollution varied from highly contaminated to moderate contamination. The possible health risks at various exposure routes have also been estimated. The single-metal and cumulative-metals health risks (cancer and noncancer) of adults and children due to chronic exposure to soil and consumption of lentils were estimated using the health quotient and health index values as per the United States Environmental Protection Agency guidelines. Thus, the results revealed no significant adverse health risks (cancer and noncancer) for adults and children. Therefore, the inhabitants in the study area have no significant health impacts due to either the consumption of lentil crops or exposure to agricultural soil particles.

A multi-objective model for the assessment of potential environmental risk using big data covering air quality

A multi-objective model for the assessment of potential environmental risk using big data covering air quality

Potential risk assessment of the large hydropower station dumpsite using numerical simulation: a case study in Shanxi Province, China

Potential risk assessment of the large hydropower station dumpsite using numerical simulation: a case study in Shanxi Province, China

Occlusion-aware collision avoidance trajectory planning with potential collision risk assessment for autonomous vehicle

Motion planning for autonomous vehicles relies heavily on perception and prediction results to find a safe, collision-free local trajectory that adheres to traffic rules. However, vehicle perception is frequently limited by occlusion, and the generation of safe local trajectories with restricted perception is a significant challenge in the field of motion planning. This paper introduces a collision avoidance trajectory planning algorithm that considers potential collision risks, within a hierarchical framework of sampling and optimization. The primary objective of this work is to generate trajectories that are safer and align better with human driver behavior while considering potential collision risks in occluded regions. Specifically, in occlusion scenarios, the state space is discretized, and a dynamic programming algorithm is used for a sampling-based search to obtain initial trajectories. Additionally, the concept of a driving risk field is introduced to describe potential collision risk elements within the human-vehicle-road environment. By drawing inspiration from graph search algorithms, potential collision risk areas are accurately described, and a cost function is proposed for evaluating potential risks in occluded regions. Drivers typically exhibit conservative and cautious driving behavior when navigating through occluded regions. The proposed algorithm not only prioritizes driving safety but also considers driving efficiency, thereby reducing the vehicle's conservativeness when passing through occlusions. The research results demonstrate that the ego vehicle can actively avoidblind spots and tends to move away from occluded regions, aligning more closely with human driver behavior.

Keperluan Mengenalpasti Risiko Dalam Proses Istibdal Harta Wakaf

Waqf is the dedication of assets by a Muslim for any purpose recognised by Islamic law as religious, pious, or charitable. Therefore, careful management of waqf properties is vital to prevent potential exposure to threats and issues that could hinder the achievement of waqf objectives. Comprehensive identification and management of risks in the istibdal process of waqf property can contribute to enhancing the reputation of the waqf institution and fostering trust among waqf donors. This can also help reduce disputes arising from a lack of understanding about the istibdal process within the community. Therefore, this study examines the need to identify risks in the istibdal process of waqf assets in Malaysia, using qualitative methods to analyse secondary data from journal articles, reports from State Islamic Religious Councils (SIRC), and websites, according to the theme of this study. The assessment of potential risks can inform the implementation of control actions, ensuring a reasonable level of assurance in achieving waqf goals. This will assist the waqf institution in making decisions related to istibdal waqf, reducing risks, and ensuring the sustainability of waqf assets. These efforts can strengthen the public's confidence in participating in waqf activities and maintaining the reputation and accountability of waqf institutions.

"ORGANIZATIONAL AND LEGAL PECULIARITIES OF CARICC ACTIVITY IN THE SPHERE OF COMBATING DRUG TRAFFICKING IN CENTRAL ASIA"

The article is devoted to organizational and legal peculiarities of activity of the Central Asian Regional Information and Coordination Center for Combating Illicit Trafficking of Narcotic Drugs, Psychotropic Substances and their Precursors (CARICC) as an interstate body designed to assist regional cooperation in combating illicit drug trafficking through exchange and analysis of operational information, organization and coordination of joint operations. The author of the article notes the importance of multilateral format of cooperation in Central Asia in the field of combating drug trafficking and search for joint responses to the drug threat. It is suggested to use CARICC analytical materials in terms of strategic analysis of the situation related to drug production in Afghanistan, assessment of potential risks and threats to Central Asian states from drug trafficking. In recent years, Uzbekistan's role in the world arena has been growing, and the country's positive influence on international processes has been increasing due to the pragmatic and active foreign policy pursued by the country's leadership. In this context, the country's active participation in multilateral cooperation institutions - international and regional organizations, including the CARICC format - plays an important role.

Changes in clozapine dose and concomitant medication - a 10-year comparative study

IntroductionClozapine is an atypical antipsychotic approved for treatment-resistant schizophrenia. Although effective, possible side effects make its underutilization still a current problem. The type of titration and dosages used differ worldwide.ObjectivesTo asses doses of clozapine and concomitant medications used in schizophrenia during 2012-2013 versus 2022-2023.MethodsA retrospective observational study analysing clozapine doses and concomitant treatment used in schizophrenia from 2012-2013 compared to 2022-2023. Data were collected from the medical charts of patients admitted to the Clinical Hospital of Psychiatry and Neurology Brasov, Romania, during 2012-2013 and 2022-2023.ResultsIn the total of 570 patients who were admitted in 2012-2013 with a diagnosis of paranoid schizophrenia, 69 (12,10%) of them were treated with clozapine.Of the 69 cases, 53,62% patients were females, mean age was 40,95 years (SD = ±10,32), with an average of onset age 23,17 (SD=±6,21). The average length of stay for hospitalization was 24,97 days (SD= ±12,65). The mean clozapine dose was 393,47 ((SD= ±183,69), with a minimum dose of 100mg/day and a maximum dose of 800mg/day. 37,68% of patients received concomitant treatment with benzodiazepines, mood stabilisers or sedative-hypnotic drugs. None of the patients received concomitant treatment with another antipsychotic.Among the total of 356 patients admitted with the diagnosis of paranoid schizophrenia during the 2022-2023 period, 72 (20,22%) of the patients were treated with clozapine. 72,22% patients were females, mean age was 49,12 years (SD = ±11,16), with an average of onset age 25,04 (SD=±6,40). The average length of stay for hospitalization was 18,58 days (SD= ±13,78). The mean clozapine dose was 275,34 (SD= ±146,7), with a minimum dose of 25mg/day and a maximum dose of 600mg/day. 72,22% of patients received concomitant treatment with benzodiazepines, mood stabilisers, sedative-hypnotic drugs or with another antipsychotic. Antipsychotics used in combination with clozapine were both oral (risperidone, amisulpride, quetiapine, aripiprazole) and long-acting injectable (aripiprazole, risperidone, paliperidone, flupentixol decanoate).ConclusionsClozapine remains the drug of choice in treatment-resistant schizophrenia even after 10 years, but its mode of administration has changed over time. While the doses of clozapine used have decreased, the percentage of patients receiving concomitant treatment has doubled.Although some side effects of clozapine are dose-dependent, lowering doses and combining with other adjuvant treatment is not always a better option, as polypragmacy and possible adverse effects combined can lead to reduced adherence.The decision to increase the dose of clozapine or to use concomitant (combination) treatment depends on individual factors, including the patient’s clinical condition, response to treatment, and the assessment of potential risks and benefits.Disclosure of InterestNone Declared

Assessment of elemental chemistry, spatial distribution, and potential risks of road-deposited dusts in Sharjah, United Arab Emirates

Road dust is a major source of pollution in the environment, carrying different pollutants, including heavy metals and metalloids, from one location to another. This study assesses the concentrations of eight heavy metals and one metalloid (Zn, Pb, Mn, Fe, Cr, Cu, Cd, Ni, and As) in dust samples collected from sixty-eight streets of Sharjah, United Arab Emirates using ICP-OES, as well as investigates their effects on both the environment and humans. Mean concentrations of the elements in μg/g across the sites were 392 ± 46 (Zn), 68.28 ± 11.3 (Pb), 1437 ± 67 (Mn), 39,481 ± 4611 (Fe), 460 ± 31 (Cr), 150 ± 44 (Cu), 1.25 ± 0.65 (Cd), 856 ± 72 (Ni), and 0.97 ± 0.28 (As). The Cdeg and ERI calculated from the study were 54.79 and 573, respectively, suggesting varying pollution levels. The highest contributions were from Ni, Cd, Zn, Cu, Cr, and Pb, especially in areas with heavy traffic. The non-carcinogenic risk assessments were generally low for the three routes of exposure, except HQoral that was slightly higher for children. Similarly, none of the elements exhibited any carcinogenic risk except chromium. Overall, the cancer risk is considered low. In view of the limited studies from UAE in relation to the metal content of road-deposited dusts, the current study serves as novel knowledge, especially in the context of geographical areas with a higher occurrence of sandstorms and the presence of particulate matter. The study also adds to the global understanding of the contribution of street dust to environmental pollution and its implications for human health.

Potential Health Risk Assessment for Nitrate Contamination in the Groundwater of Mersin Province, Türkiye

Though groundwater is one of the most significant natural water sources, its quality is deteriorating due to the anthropogenic pressures that poses health risks for people. In this study, potential health risk assessment for nitrate pollution in groundwater of Mersin Province was determined by commonly using health indices. Study findings indicated that the calculated Hazard Index (HI) values varied between 0.001 and 17.89 for the adults whilst the HI values ranging from 0.001 to 29.87 for the children. The HI values in the groundwater of Erdemli, Göksu and Anamur regions showed low chronic health risk for the adults and children (HI≤1). However, the calculated health risk indices indicated significant health hazards for the children inhabited between Tarsus and Çeşmeli regions (HI≥4.00) due to severe nitrate contamination originated from terrestrial sources. The findings of this study performed in the Mersin Province showed the sustainable management of groundwater policies is needed to reduce nitrate contamination and potential health hazards of the groundwater of studied and other regions in Türkiye.

HYGIENIC RISK ASSESSMENT OF ETOFENPROX-BASED INSECTICIDES USAGE FOR HUMANS BY TOXICITY PARAMETERS

Background. As of 2023, 135 pyrethroid-based insecticides have been registered in Ukraine. The Ukrainian pesticide market offers products based on the new active ingredient etofenprox. According to the current legislation, the acceptable daily intake (ADI) of the new active ingredient etofenprox must be substantiated at the pre-registration stage.
 Aim: hygienic assessment of the toxic properties of the third-generation pyrethroid substance etofenprox and justification of the ADI of etofenprox, the active ingredient of the insecticide Trebon. Potential risk assessment for the workers and the general population. Determining the necessity of monitoring on environmental objects.
 Materials and methods. In the course of the work expert analysis, toxicological and hygienic research methods have been used.
 Results. It has been proven that etofenprox, in accordance with Sanitary Rules and Standards (SanPiN) 8.8.1.002-98, is of low danger – for oral and percutaneous ingestion and for allergenic effects, dangerous – for inhalation, moderately dangerous – for irritating effects on the skin and mucous membranes of the eyes. Integral hazard class - II (Limitation criteria - inhalation toxicity).
 The value of the ADI was estimated at the level of 0.003 mg/kg, based on toxicity data for mice in a chronic experiment and hazard class III for reproductive toxicity, embryotoxicity, teratogenicity (3.1 mg/kg is the lowest dose), factor of safety 1000 has also been considered.
 Conclusion. There has been established the necessity to consider the toxicity data of etofenprox when deciding on the need to perform monitoring studies of the content of etofenprox in water, soil, air, and agricultural raw materials.

Financial Calculation Problems and Countermeasure Analysis of Large-Scale Engineering Construction Projects

The financial aspects of large-scale engineering construction projects profoundly influence their success. Strengthening cost control and establishing a scientific financial evaluation system can enhance the project’s economic benefits, minimize unnecessary costs, and provide decision-makers with a robust financial foundation. Additionally, implementing an effective cash flow control mechanism and conducting a comprehensive assessment of potential project risks can ensure financial stability and mitigate the risk of fund shortages. Developing a practical and feasible fundraising plan, along with stringent fund management practices, can prevent fund wastage and optimize fund utilization efficiency. These measures not only facilitate smooth project progression and improve project management efficiency but also enhance the project’s economic and social outcomes.

Assessment ofdeltamethrin-induced DNA damage, neurotoxic and neuroimmune effects inthe brain tissue ofbrown trout (Salmo trutta fario).

This study investigated the impact ofdeltamethrin (DM) toxicity onbrown trout (Salmo trutta fario), examining its effects onthe immune system, including the white blood cell (WBC), lymphocyte (Lym), total immunoglobulin (T.Ig), and lysozyme levels, aswell asits neurotoxic consequences onthe brain tissue. Theneurotoxic effects encompassed oxidative stress, the activity ofthe antioxidant enzymes, such asthe superoxide dismutase (SOD) and catalase (CAT), acetylcholinesterase (AChE) activity, and DNA damage using 8-hydroxy-2-deoxyguanosine (8-OHdG). The DM exposure led toelevated levels ofmalondialdehyde (MDA), and 8-OHdG, while concurrently causing areduction inthe AChE activity, protein and lipid content, WBC count, Lym, lysozyme activity, T.Ig levels, aswell asthe SOD and CAT levels inthe brain tissues ofgroups2 and 3 when compared tothose ingroup1. Insummary, the findings ofthis study strongly indicate that DM induces DNA damage, immunotoxicity, and neurotoxicity inthe brain tissue ofbrown trout, primarily due tothe excessive production ofreactive oxygen species (ROS). Moreover, the observed dose-dependent responses ofDM tothe environmental concentrations onall theinvestigated parameters suggest its potential utility inaquaculture risk assessment.

Basin scale monitoring of microplastics and phthalates in sediments from the Persian Gulf and the Gulf of Makran using GIS-based algorithms: Insights towards spatial variation and potential risk assessment

Information on sedimentary microplastics and phthalates has been restricted to the coastal regions of the Persian Gulf and the Gulf of Makran. Our basin-wide study monitored their levels, spatial behaviors, and potential risks using GIS-based techniques. Microplastics and phthalates ranged from 5 to 75 particles/kg d.w and 0.004–1.219 μg g−1 d.w, respectively. Microplastics were in the size category of 100 μm to 3 mm, and black microfibers (< 1 mm) and high-density polymers were dominant. The total number of microplastics was between 356.333 × 1012 and 469.075 × 1012 particles in the surface sediments of the studied regions (confidence interval = 99 %). Diethylhexyl phthalate (DEHP) and Di-isobutyl phthalate contributed 88 % of detected phthalates. Significant correlations among microplastic abundance, total phthalates, and DEHP were distinguished (p < 0.05). Overall, the findings reiterated the widespread presence of microplastics and a potential link between phthalates and microplastics. Semi-variogram, cluster Voronoi polygons, and Trend analysis identified spatial outliers and major deposition sites of microplastics and phthalates and consequently outlined the localities where upcoming studies should be concentrated. A hotspot of potential risks was marked using Fuzzy logic and GIS-based algorithms in the Sea of Makran, covering an area equal to 342. 99 km2.

Use of inhaled vasodilators in ARDS patients

Abstract:&#x0D; Acute Respiratory Distress Syndrome (ARDS) is a severe lung injury leading to bilateral lung opacities and severe hypoxemic respiratory failure. It results from acute inflammation, endothelial dysfunction, and disruption of the alveolar-capillary membrane. ARDS management encompasses lung-protective supportive care such as lung-protective ventilation strategies. Inhaled pulmonary vasodilators show potential as adjunctive therapies for refractory hypoxemia and hold promise in improving oxygenation and reducing pulmonary vascular resistance in severe ARDS. However, their impact on mortality remains uncertain and current evidence supports their role as rescue therapies. Prudent consideration and assessment of potential benefits and risks are crucial when integrating these agents into clinical practice.

Assessment of Potential Human Health Risk Associated With Heavy Metals in Soil – Vegetables System Irrigated by Rift Valley Lake Ziway, Ethiopia

Metal contamination of vegetables is a major concern, especially in areas where irrigation has been used for a long time. The Central Ethiopian Rift Valley Region is highly affected due to the heavy use of agrochemicals throughout the year. Although some studies have been conducted on the concentration and level of heavy metal pollution, little attention has been paid to their impact on human health. This study determined the concentrations of nine metals (As, Cd, Cr, Co, Cu, Hg, Ni, Pb, and Zn) in a soils and vegetables (tomatoes and onions) irrigated by Lake Ziway, Ethiopia. An inductively coupled plasma optical emission spectrometer (ICP-OES) was used to determine the heavy metal levels. Moreover, the study evaluated the health risks associated with consuming contaminated vegetables by employing major indices, including non-carcinogenic and carcinogenic risks. The results showed that the mean concentrations of Pb, As, Hg, and Cr in all tomato and onion samples and the average Zn, Pb, Cd, and Hg levels in all soil samples exceeded the FAO/WHO threshold. Non-carcinogenic health risk estimates showed that As, Pb, Hg, and Co for children and Pb and Co for adults had THQ values greater than 1, indicating the possibility of systemic health risks. Carcinogenic health risk showed that Ni posed a risk of developing cancer for both adults and children, with values ranging from 10−3 to 10−1. In addition, children are likely to have a higher cancer risk due to exposure to As and Cr. Therefore, it is crucial to raise awareness among stakeholders and implement effective monitoring policies to safeguard public health both within and beyond the study area.