Potential Exploitation Research Articles

The Ethical Implications of Integrating Complementary and Alternative Medicine (CAM) in Chinese Psychological Practice

This paper meticulously delves into the intricate ethical implications that arise from the integration of Complementary and Alternative Medicine (CAM) into the realm of Chinese psychological practice. The surge in interest in holistic well-being has spurred the incorporation of CAM modalities within psychology. This convergence lays bare a tapestry of intricate ethical quandaries. With a meticulous and rigorous examination, this study navigates the core ethical principles, including the imperative commitments to public welfare, shielding against potential harm, and upholding individual autonomy. The exploration unearths multifaceted challenges spanning transparency, the intricacies of accountability, the nuances of informed consent, and the shadows of potential exploitation. In response to these complexities, the paper advocates for strategic measures such as fostering interprofessional collaboration, catalyzing governmental initiatives, and embracing qualitative methodologies. Inescapably, the study underscores the pressing need for a responsible and reasonable integration that ensures the delivery of comprehensive and patient-centered care while aligning with China's constantly evolving mental health landscape. By engaging rigorously with these ethical dimensions, the integration of CAM emerges as a pivotal contributor to an inclusive and all-encompassing mental health framework.

Targets of tumor microenvironment for potential drug development

AbstractThe tumor microenvironment (TME) is the ecosystem surrounding a tumor, which usually consists of nontumoral cells or components, and molecules they produce and release. The frequent and continuous interplay between tumor cells and the TME strongly affects tumor development, disease progression, metastasis, and responses to therapeutic interventions. As a hub of potential therapeutic targets, the TME has gained appreciable momentum in cancer research. Here we systematically review the progress in targeting the TME as a strategy to develop novel antitumor drugs from the immunological, stromal and extracellular matrix components of the TME, shedding light on its complex synergies with tumor cells. This exploration highlights the transformative potential these elements hold in refining cancer treatment approaches. This thorough examination not only accentuates the TME's multifaceted nature but also positions it as a formidable avenue for propelling forward the paradigms of cancer therapy. This review aims to foster a deeper understanding of the TME's role in oncogenesis and its potential exploitation in advancing targeted, efficacious cancer treatments, marking a significant stride in the realm of cancer research.

Translating microcalcification biomarker information into the laboratory: A preliminary assessment utilizing core biopsies obtained from sites of mammographic calcification

Rationale and objectivesThe potential of breast microcalcification chemistry to provide clinically valuable intelligence is being increasingly studied. However, acquisition of crystallographic details has, to date, been limited to high brightness, synchrotron radiation sources. This study, for the first time, evaluates a laboratory-based system that interrogates histological sections containing microcalcifications. The principal objective was to determine the measurement precision of the laboratory system and assess whether this was sufficient to provide potentially clinical valuable information. Materials and methodsSections from 5 histological specimens from breast core biopsies obtained to evaluate mammographic calcification were examined using a synchrotron source and a laboratory-based instrument. The samples were chosen to represent a significant proportion of the known breast tissue, mineralogical landscape. Data were subsequently analysed using conventional methods and microcalcification characteristics such as crystallographic phase, chemical deviation from ideal stoichiometry and microstructure were determined. ResultsThe crystallographic phase of each microcalcification (e.g., hydroxyapatite, whitlockite) was easily determined from the laboratory derived data even when a mixed phase was apparent. Lattice parameter values from the laboratory experiments agreed well with the corresponding synchrotron values and, critically, were determined to precisions that were significantly greater than required for potential clinical exploitation. ConclusionIt has been shown that crystallographic characteristics of microcalcifications can be determined in the laboratory with sufficient precision to have potential clinical value. The work will thus enable exploitation acceleration of these latent microcalcification features as current dependence upon access to limited synchrotron resources is minimized.

Maize catalases are recruited by a virus to modulate viral multiplication and infection.

Given the detrimental effects of excessive reactive oxygen species (ROS) accumulation in plant cells, various antioxidant mechanisms have evolved to maintain cellular redox homeostasis, encompassing both enzymatic components (e.g., catalase, superoxide dismutase) and non-enzymatic ones. Despite extensive research on the role of antioxidant systems in plant physiology and responses to abiotic stresses, the potential exploitation of antioxidant enzymes by plant viruses to facilitate viral infection remains insufficiently addressed. Herein, we demonstrate that maize catalases (ZmCATs) exhibited up-regulated enzymatic activities upon sugarcane mosaic virus (SCMV) infection. ZmCATs played crucial roles in SCMV multiplication and infection by catalysing the decomposition of excess cellular H2 O2 and promoting the accumulation of viral replication-related cylindrical inclusion (CI) protein through interaction. Peroxisome-localized ZmCATs were found to be distributed around SCMV replication vesicles in Nicotiana benthamiana leaves. Additionally, the helper component-protease (HC-Pro) of SCMV interacted with ZmCATs and enhanced catalase activities to promote viral accumulation. This study unveils a significant involvement of maize catalases in modulating SCMV multiplication and infection through interaction with two viral factors, thereby enhancing our understanding regarding viral strategies for manipulating host antioxidant mechanisms towards robust viral accumulation.

Assigning the unassigned: A signature-based classification of rDNA metabarcodes reveals new deep-sea diversity.

Environmental DNA metabarcoding reveals a vast genetic diversity of marine eukaryotes. Yet, most of the metabarcoding data remain unassigned due to the paucity of reference databases. This is particularly true for the deep-sea meiofauna and eukaryotic microbiota, whose hidden diversity is largely unexplored. Here, we tackle this issue by using unique DNA signatures to classify unknown metabarcodes assigned to deep-sea foraminifera. We analyzed metabarcoding data obtained from 311 deep-sea sediment samples collected in the Clarion-Clipperton Fracture Zone, an area of potential polymetallic nodule exploitation in the Eastern Pacific Ocean. Using the signatures designed in the 37F hypervariable region of the 18S rRNA gene, we were able to classify 802 unassigned metabarcodes into 61 novel lineages, which have been placed in 27 phylogenetic clades. The comparison of new lineages with other foraminiferal datasets shows that most novel lineages are widely distributed in the deep sea. Five lineages are also present in the shallow-water datasets; however, phylogenetic analysis of these lineages separates deep-sea and shallow-water metabarcodes except in one case. While the signature-based classification does not solve the problem of gaps in reference databases, this taxonomy-free approach provides insight into the distribution and ecology of deep-sea species represented by unassigned metabarcodes, which could be useful in future applications of metabarcoding for environmental monitoring.

From Meditation to Techno-Mindfulness: On the Medicalization of Contemplative Practices and Future Prospects

This article explores the historical transformation of mindfulness, through a process of transculturation and commodification, into a biopolitical tool and analyzes possible future scenarios in which this tool will acquire even greater biopolitical strength through the integration of technological devices and artificial intelligence applications, particularly focusing on the growing divide between mindfulness-based therapies and traditional meditation. While both methodologies share the common objective of providing health and psychophysical benefits, they differ fundamentally in their theoretical frameworks, with mindfulness being egolatric and performance oriented while traditional meditation emphasizes transcending psychophysical identity. The development of mindfulness has been influenced by the sociocultural context of neoliberal and capitalist societies, resulting in a model that fosters self-regulation and emphasizes social control. The article also examines the potential biopolitical risks arising from the integration of AI-powered tools into mindfulness-based therapies. The increasing use of digital devices and applications for monitoring physical and mental health may contribute to a society characterized by constant self-surveillance and self-monitoring, reinforcing biopolitical control of the body. Consequently, this raises critical questions regarding the limits of surveillance and the potential exploitation of vulnerabilities through the incorporation of AI-powered tools.

Bioprospecting the roles of Trichoderma in alleviating plants’ drought tolerance: Principles, mechanisms of action, and prospects

Drought-induced stress represents a significant challenge to agricultural production, exerting adverse effects on both plant growth and overall productivity. Therefore, the exploration of innovative long-term approaches for addressing drought stress within agriculture constitutes a crucial objective, given its vital role in enhancing food security. This article explores the potential use of Trichoderma, a well-known genus of plant growth-promoting fungi, to enhance plant tolerance to drought stress. Trichoderma species have shown remarkable potential for enhancing plant growth, inducing systemic resistance, and ameliorating the adverse impacts of drought stress on plants through the modulation of morphological, physiological, biochemical, and molecular characteristics. In conclusion, the exploitation of Trichoderma's potential as a sustainable solution to enhance plant drought tolerance is a promising avenue for addressing the challenges posed by the changing climate. The manifold advantages of Trichoderma in promoting plant growth and alleviating the effects of drought stress underscore their pivotal role in fostering sustainable agricultural practices and enhancing food security.

Once Again About the Problems of Preserving Objects of Immovable Cultural Heritage from the Standpoint of Collective and Individual Consumer Perception

The concept of attitude towards objects of immovable cultural heritage, formed more than a century ago, is relevant today, based on the premises that these material objects form an objective value in the perception and understanding of any individual, any society, any civilization. The purpose of the article is to conduct a preliminary analysis of the problems that form the understanding of the value of cultural heritage, preservation and careful treatment of it in the modes of restoration activities and restoration work. Achieving the goal can be the solution of a number of problems regarding the proper state protection of objects of immovable cultural heritage and the necessary assistance from the state, public institutions and international organizations, as well as taking into account the assigned status of the object in the matter of rescue, restoration and gentle scientific restoration. Currently existing directions and developments in a comprehensive assessment of architectural monuments of the past, observation methods, active comparative studies, and statistical measurements are considered as methodological and instrumental approaches to solving emerging problems. The results obtained by the authors included a study of the complex interaction and isolated influence on the category of value of such significant features-factors as evaluation criteria such as cultural and collective memory, historical reputation in their meaning for the self-identification of society and in the development of strategies in the field of preservation of cultural heritage objects and their use in the exploitation of the recreational potential of the destination by the tourism business. Examples from domestic restoration and construction practice and Western European experience, used to minimize the negative consequences of the increasing anthropogenic load on the territory, are discussed. At the end of the material, prospects for further research are indicated and the necessary conclusions are drawn.

Role of microstructure in the exploitation of self-healing potential in form-stable composite phase change materials based on immiscible alloys

Metallic Phase Change Materials (PCMs), based on solid-liquid transitions, represents one of the most promising technologies for efficient Thermal Energy Storage (TES), due to their superior thermal conductivity and energy storability per unit volume, but suffer of limited solutions for their handling at the molten state. The use of Miscibility Gap Alloys (MGAs) allows to manage PCM volume expansion and keep it confined when molten, preventing interaction with the environment. A relevant example is provided by the Al-Sn system, where Al covers the role of the high-temperature stable and highly thermal-conductive passive matrix and Sn the active PCM. The alloy can thus be considered a Composite PCM (C-PCM). The response fastness of these systems depends on their thermal diffusivity, subjected to abrupt variations under the presence of discontinuities and damages. In this sense, the authors investigated the possibility to employ molten Sn mobility in a potentially damaged C-PCM for self-healing purposes, aimed to restore, at least partially, the material continuity and thus its thermal diffusivity. Exudation heat treatments above the melting temperature of Sn were performed on sets of Al-40%wt. Sn metallic composites, produced either with powder metallurgy or liquid metal routes, in order to quantify and assess the mobility of the Sn under simulated operating conditions. Exudation tests assess Simple Mixed powders and liquid metal routes sample as the ones with the highest healing potential. Al dissolution and re-deposition was established by EDS analyses as one of the principal Sn mobility mechanisms. Laser Flash Analysis tests, as well as microstructural investigations, were performed on the samples before and after both healing-focused and simulated service heat treatments to evaluate the changes of thermal diffusivity. Healing-focused treatment at 250°C for 1 hour generally displayed a moderate thermal diffusivity recovery and simulated service by shorter cycles between 170°C and 270°C slightly reduce it. The beneficial role of healing focused heat treatments at 250°C for 1 hour suggests that the presence of fully molten Sn phase during service for relatively long time could be beneficial for functional healing. The requirements of suitable Al-Sn microstructures for self-healing purposes, granting at the same time the C-PCM functionalities, i.e., thermal energy storage and form-stability, were set.

Transplantation in the Context of Migration and Refugees: A Summary of the DICG and TTS Ethics Committee Workshop, Buenos Aires, Argentina, September 2022.

Global conflicts and humanitarian crises have resulted in an unprecedented number of refugees and migrants. This challenges the limited resources of health care systems and jeopardizes the availability of transplant care for these deserving migrants and refugees. This was the basis for a workshop held during the Congress of the Transplantation Society (Buenos Aires, 2022). We elaborate on the proceedings of the workshop entitled "Transplantation in the Context of Migration and Refugees," organized by the Ethics Committee of The Transplantation Society and Declaration of Istanbul Custodian Group. Transplant providers from around the world shared strategies of how each region has responded to providing access to care for refugees and migrants in need of transplant services. The potential exploitation of this vulnerable group leading to illicit organ removal was addressed for each region. The Transplantation Society, Declaration of Istanbul Custodian Group, and global transplant community should continue to focus on the status of refugees and migrants and collaborate on strategies to provide access to transplant care for this deserving population. Global cooperation will be essential to provide vigilant oversight to prevent exploitation of this vulnerable population.

Advanced protein-embedded bimetallic nanocomposite optimized for in vivo fluorescence and magnetic resonance bimodal imaging

HypothesisThe development of bimodal imaging probes represents a hot topic of current research. Herein, we deal with developing an innovative bimodal contrast agent enabling fluorescence imaging (FI)/magnetic resonance imaging (MRI) and, simultaneously, consisting of biocompatible nanostructures. Optimized synthesis of advanced protein-embedded bimetallic (APEBM) nanocomposite containing luminescent gold nanoclusters (AuNC) and superparamagnetic iron oxide nanoparticles (SPION), suitable for in vivo dual-modal FI/MR imaging is reported. ExperimentsThe APEBM nanocomposite was prepared by a specific sequential one-pot green synthetic approach that is optimized to increase metals (Au, Fe) content and, consequently, the imaging ability of the resulting nanostructures. The protein matrix, represented by serum albumin, was intentionally chosen, and used since it creates an efficient protein corona for both types of optically/magnetically-susceptible nanostructures (AuNC, SPION) and ensures biocompatibility of the resulting APEBM nanocomposite although it contains elevated metal concentrations (approx. 1 mg·mL−1 of Au, around 0.3 mg·mL−1 of Fe). In vitro and in vivo imaging was performed. FindingsSuccessful in vivo FI and MRI recorded in healthy mice corroborated the applicability of the APEBM nanocomposite and, simultaneously, served as a proof of concept concerning the potential future exploitation of this new FI/MRI bimodal contrast agent in preclinical and clinical practice.

Recent Developments of Carbon Dots for Advanced Zinc‐Based Batteries: A Review

AbstractRechargeable Zn‐based batteries provide a compelling supplement to subsistent energy storage devices owing to their high energy density, good safety, and low cost. Nevertheless, inherent imperfections such as dendrite growth, side reactions, and andante reaction kinetics, severely impede their commercialization. As new 0D nanomaterials, carbon dots (CDs) with unique characteristics and excellent electrochemical activity, exhibit promising potential exploitation in electrochemistry and electrocatalysis areas. Herein, the adhibition of CDs in resolving the aforementioned drawbacks of Zn‐based batteries is introduced. To begin with, concepts, physicochemical properties, and synthetic methods of CDs are discussed. Next, recent developments and advances exploiting CDs in respectively ameliorating the performance of the Zn anode, the cathode, and electrolytes of Zn ion batteries and bifunctional electrocatalytic activities including oxygen reduction reaction and oxygen evolution reaction for Zn‐air batteries, are roundly reviewed and minutely generalized. Finally, current challenges and prospects are surveyed as well, aiming to offer a reference for the blossom of advanced Zn‐based batteries.

Complete Whole-Genome Sequence of Streptomyces sp. MUM 178J, a Potential Anti-Vibrio Agent

Streptomyces sp. is a group of filamentous, Gram-positive bacteria notoriously known for their capabilities in producing bioactive compounds that have been used as novel drugs and lead in drug development. The Streptomyces sp. MUM 178J was isolated from a mangrove forest in Malaysia. This isolate was found to harbor anti-Vibrio properties as its crude extract inhibited the growth of multidrug-resistant Vibrio parahaemolyticus. Therefore, the strain was subjected to whole genome sequencing to unearth its genomic potential. The genome of Streptomyces sp. MUM 178J consists of 6,699,249 bp with a G+C content of 71.3%. 66 tRNA genes and 18 rRNA genes were also predicted to be present within the genome. Further analysis with the bioinformatics tool, antiSMASH (antibiotics & Secondary Metabolite Analysis Shell), detected nine biosynthetic gene clusters displaying more than 70% similarity to known gene clusters, including one associated with melanin production. Melanin has demonstrated antagonistic activity against the growth of members of the Vibrio family, including V. parahaemolyticus. This indicates the potential correlation between the production of melanin and the anti-Vibrio properties of MUM 178J. The availability of the whole genome sequence of Streptomyces sp. MUM 178J allows for future in-depth investigation and potential exploitation of MUM 178J to harvest useful bioactive compounds.

Artificial Intelligence (AI)-Based Campaign in the Implementation of General Elections

This research aims to analyze Artificial Intelligence (AI)-based campaigns in implementing General Elections. The research method used is normative legal research, with statutory and conceptual approaches. The research results explain the limitations of the artificial intelligence (AI) campaign. These include the use of digital or AI technology that is not significantly different from reality as it currently exists; all digital content or AI-produced content is required to have a watermark or information label that includes the name of the application or website where the content was created, the creation date, does not contain racism or words or sentences that have multiple interpretations, and does not use a person without consent, who has died, and minors. There is an urgent need for an AI supervisory commission, as well as the need for special legislation about AI to avoid potential exploitation. Furthermore, it is necessary to amend Article 1 Number 35 and Article 274 Paragraph 4 of Law No. 7 of 2017 concerning the General Election, so AI is applicable as campaign material but only if it uses watermarks, is not significantly different from reality, does not contain racism, and does not use living or deceased people without consent.

Inhibitors of NAD+ Production in Cancer Treatment: State of the Art and Perspectives.

The addiction of tumors to elevated nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of cancer metabolism. Obstructing NAD+ biosynthesis in tumors is a new and promising antineoplastic strategy. Inhibitors developed against nicotinamide phosphoribosyltransferase (NAMPT), the main enzyme in NAD+ production from nicotinamide, elicited robust anticancer activity in preclinical models but not in patients, implying that other NAD+-biosynthetic pathways are also active in tumors and provide sufficient NAD+ amounts despite NAMPT obstruction. Recent studies show that NAD+ biosynthesis through the so-called "Preiss-Handler (PH) pathway", which utilizes nicotinate as a precursor, actively operates in many tumors and accounts for tumor resistance to NAMPT inhibitors. The PH pathway consists of three sequential enzymatic steps that are catalyzed by nicotinate phosphoribosyltransferase (NAPRT), nicotinamide mononucleotide adenylyltransferases (NMNATs), and NAD+ synthetase (NADSYN1). Here, we focus on these enzymes as emerging targets in cancer drug discovery, summarizing their reported inhibitors and describing their current or potential exploitation as anticancer agents. Finally, we also focus on additional NAD+-producing enzymes acting in alternative NAD+-producing routes that could also be relevant in tumors and thus become viable targets for drug discovery.

Unlocking the potential of bacterial endophytes from medicinal plants for drug discovery.

Among the plant-associated microorganisms, the so-called endophytes continue to attract much attention because of their ability not only to protect host plants from biotic and abiotic stress factors, but also the potential to produce bioactive secondary metabolites. The latter property can elicit growth-promoting effects on plants, as well as boost the production of plant-specific secondary metabolites with valuable pharmacological properties. In addition, endophyte-derived secondary metabolites may be a rich source for the discovery of drugs to treat various diseases, including infections and cancer. However, the full potential of endophytes to produce bioactive secondary metabolites is often not revealed upon conventional cultivation in the laboratory. New advances in genomics and metabolic engineering offer exciting opportunities for the exploration and exploitation of endophytes' biosynthetic potential. This review focuses on bacterial endophytes of medicinal plants, some of their secondary metabolites and recent advances in deciphering their biosynthesis. The latter may assist in genetic engineering efforts aimed at the discovery of novel bioactive compounds with the potential to be developed into drugs.

Reflections of Medical Social Workers’Roles in Living Organ Donors’Psychosocial Assessment: Human Rights and Social Justice Perspectives

研究目的：本研究以人權與社會正義觀點來探討醫務社會工作人員在活體器官捐贈社會心理評估中的角色、任務以及工作內容，以確保捐贈者自主、自願及知情下同意器官捐贈的行為。<br />研究方法：本研究採立意取樣，訪談現職從事活體器官捐贈社會心理評估工作或曾任職衛生福利部核准之活體肝臟移植或活體腎臟移植醫院之醫務社會工作人員。<br />研究結果：訪談資料顯示，醫務社會工作人員在活體器官捐贈社會心理評估的工作內容是透過會談來確認捐贈者是權利主體，其捐贈決定是自主、自願以及知情下同意；同時，捐贈者的性別、身心障礙或族群等脆弱性特質形塑捐贈決策中的角色期待、家庭關係壓力與脅迫。<br />研究結論：醫務社會工作人員在捐贈者社會心理評估裡的角色既是知情同意倫理彰顯者，以捐贈者為中心，進行充權，使其具備權利意識來決定同意或拒絕器官捐贈；也是捐贈者權益維護者，協助捐贈者審視捐贈決策的情境與社會脈絡，保護捐贈者不因脆弱性特質，遭受不公對待，而進行捐贈決策。Research Purpose Liver and kidney transplants are the most common forms of living organ transplants in Taiwan. According to Article 8, item 1, paragraphs 1 and 2 of the Human Organ Transplant Act, consent to organ donation should be given in a condition of“sound mental capacity”and“free will.”To avoid coercion or organ trafficking and selling in situations of living organ donation and transplantation, a thorough assessment and examination must be performed prior to the procedure. This study examined how medical social workers (MSWs) adopted human rights and social justice perspectives in the psychosocial assessment of living organ donors before surgery to ensure donors’autonomy and willingness. <br />Method A purposive sampling technique was adopted that involved interviewing 12 MSWs (three males and nine females) assigned to living-donor liver transplant hospitals approved by the Ministry of Health and Welfare or working in psychosocial assessment of living organ donation at the time of interviewing. Interviews were conducted between March 23 and April 10, 2021. Thematic analysis was used to analyze the qualitative data. <br />Results According to the research findings, the psychosocial assessment of living organ donation focuses on the donor’s demographic characteristics such as gender, age, marital status, and employment to ensure relationships between the donor and the recipient. It is also necessary to have information about the donor’s family system because potential donors are frequently under pressure to donate organs owing to role expectations. MSWs feel confident in their roles as professionals in the psychosocial evaluation of living organ donation since psychosocial evaluation is an essential skill to acquire in social work education. Furthermore, MSWs must ensure that potential donors’decisions are made freely and without any coercion, even though MSWs are not the only ones who respect and protect the donor’s rights to autonomy and self-determination during the psychosocial assessment process. Additionally, when donors are placed in oppressive situations during the donation decision-making process, MSWs must be aware of their vulnerability based on their gender, disability, or ethnicity to empower them to resist potential oppression or exploitation. In other words, the social work profession values the notion of social justice and emphasizes acknowledging service users’possible existence of the social injustice faced by disadvantaged groups. Psychosocial assessments of living donors help potential donors become aware of whether their characteristics, such as gender, ethnicity, or disability, cause them to be dominated and exploited. According to our findings, female family members, such as spouses, daughters, or daughters-in-law, are sometimes required to sacrifice themselves to donate living organs to other family members, especially when the female is financially reliant. <br />Conclusion The results suggest that MSWs are expected to maintain consciousness of rights to protect the free will, autonomy, and self-determination freedom of potential living organ donors. Moreover, based on social justice, MSWs are expected to protect living organ donors from the pressures caused by interpersonal relationships and social roles. Consequently, the role of medical social workers in the psychosocial evaluation of living organ donations may be viewed as an advocate for human rights and social justice practitioners.

Las condiciones de la producción agropecuaria en Boyacá

This article uses data from the Census of Agriculture 2014 pertaining to the Department of Boyacá. It connects the production performance at the municipal level to a set of rural determinants, which encompass the exploitation of the agricultural potential. This approach highlights features of the agricultural sector in Boyacá: the predominance of annual crops, the break-up of agricultural units, family arrangements to supply labor input, and the lack of a widespread export stuff, inter alia. The methodology employs a spatial approach that seeks to identify spatial patterns in the agricultural output, using the municipality as the spatial unit. We resort to spatial econometrics to model the determinants of the agricultural output, and to point out a better spatial structure according to the pool of data. The econometric results confirm a kind of spatial dependence in the error, suggesting the influence of common shocks affecting the agricultural output, everywhere the municipalities of Boyacá. Throughout the region, the traditional production profile, based on annual crops to satisfy the national consumption, prevails. This type of production depends on typical rural conditions: small plots of land, little mechanized production, family work and precarious wages.

Energy harvesting from plants using hybrid microbial fuel cells; potential applications and future exploitation.

Microbial Fuel Cells (MFC) can be fuelled using biomass derived from dead plant material and can operate on plant produced chemicals such as sugars, carbohydrates, polysaccharides and cellulose, as well as being "fed" on a regular diet of primary biomass from plants or algae. An even closer relationship can exist if algae (e.g., prokaryotic microalgae or eukaryotic and unicellular algae) can colonise the open to air cathode chambers of MFCs driving photosynthesis, producing a high redox gradient due to the oxygenic phase of collective algal cells. The hybrid system is symbiotic; the conditions within the cathodic chamber favour the growth of microalgae whilst the increased redox and production of oxygen by the algae, favour a more powerful cathode giving a higher maximum voltage and power to the photo-microbial fuel cell, which can ultimately be harvested for a range of end-user applications. MFCs can utilise a wide range of plant derived materials including detritus, plant composts, rhizodeposits, root exudates, dead or dying macro- or microalgae, via Soil-based Microbial Fuel Cells, Sediment Microbial Fuel Cells, Plant-based microbial fuel cells, floating artificial islands and constructed artificial wetlands. This review provides a perspective on this aspect of the technology as yet another attribute of the benevolent Bioelectrochemical Systems.

MICROCREDIT: A MEANS OF FINANCIAL STABILITY OR A TOOL FOR EXPLOITATION?

Microcredit has received a lot of attention lately since it is hailed as a revolutionary financial instrument for reducing poverty and promoting economic empowerment. This piece explores the dual nature of microcredit, examining how it may be used as a tool for potential exploitation as well as a means of achieving financial security. This research highlights the critical role that microcredit has had in giving marginalised populations access to capital by drawing on an extensive analysis of empirical evidence. It looks at how microcredit initiatives have boosted community development, entrepreneurship, and income production, thereby empowering people, especially women. These encouraging results highlight microcredit's capacity to promote economic resilience and financial stability. On the other hand, the research also reveals the negative aspects of microcredit. The research indicates that low-income individuals with inadequate financial and educational backgrounds are using microcredit to cover everyday household needs because there are insufficient regulating authorities in place. With no other feasible choice, these people are turning to microcredit, where they frequently run into predatory practises such excessive interest rates and forceful loan practises. The positive effects of microcredit are overshadowed by these practises, which give rise to serious ethical and social concerns.