Positive Agglutination Reaction Research Articles

THE BACILLUS DYSENTERIÆ (SHIGA) IN ITS RELATION TO THE DIARRHEAL DISEASES OF INFANTS.A CLINICAL STUDY OF TWO HUNDRED AND THIRTY-SEVEN CASES.

The early history of the work done on the dysentery bacillus has been so often published that it need not be repeated here. It is to Duval and Bassett that the credit is due of first pointing out the fact that this organism played an important part in the diarrheal diseases of infancy. Working under the direction of Dr. Flexner at the Thomas Wilson Sanitarium, Baltimore, in the summer of 1902, Duval and Bassett studied 53 cases of diarrheal disease in infants and young children, in 42 of which they demonstrated the presence of the dysentery bacillus. After a considerable number of positive cases had been found, 25 cases were taken successively and from 19 of these the dysentery organism was isolated. They established the connection between the organism and the disease by obtaining positive agglutination reactions in a very considerable number of their patients. In the autumn of 1902