Polymerization Of Methacrylate Research Articles

Hydrogel granular systems for controlled release based on (co)polymers of 2-hydroxyethyl methacrylate with polyvinylpyrrolidone (a review)

The development of polymer carriers for systems of prolonged and controlled release of substances, particularly drugs, into the action environment is a relevant task in polymer chemistry and technology. This aims to solve the problem of reducing the effective dose of a medical drug administered into the body of a person or animal. The latest achievements in the field of creating such carriers in the form of spherical particles based on 2-hydroxyethyl methacrylate and polyvinylpyrrolidone (co)polymers are analyzed and summarized. The working principles and advantages of such systems are described. The research of the synthesis regularities, structure, properties and perspectives of application of granular hydrogels based on 2-hydroxyethyl methacrylate and its copolymers with polyvinylpyrrolidone was analyzed. The mixture of decanol and cyclohexanol as a solvent for the monomer phase is substantiated. Based on the analysis of kinetic studies, the optimal technological parameters for the suspension polymerization of 2-hydroxyethyl methacrylate with polyvinylpyrrolidone were selected, and the possibility of regulating the dispersion characteristics of copolymers via changes in the technological synthesis modes was confirmed. The results of studies on the sorption-desorption properties of copolymers concerning model substances and drugs are described. The possibility of directed regulation of sorption capacity and drug release rate through changes in copolymer composition was confirmed. Methods for increasing the sorption capacity of hydrogels for drugs are proposed.

Constructing an Artificial Interface as a Bifunctional Promoter for the Li Anode and the NCM Cathode in Lithium Metal Batteries.

The bottleneck of Li metal batteries toward practical applications lies at inferior cyclability as well as Li dendrite issues. As a promising solution, an interface engineering strategy is proposed herein for the Li anode through constructing a hybrid artificial interface. It is assembled onto the Li anode using photocontrolled free radical polymerization (photo-CRP) of polyethylene glycol diacrylate-hexafluorobutyl methacrylate and hexafluorobutyl methacrylate-trifluoroethyl carbonate (PEGDA-HFMBA@HFMBA-FEMC or PH@HF layer). Among such hybrid interfaces, the interior layer of PEGDA-HFMBA exists as a protective shield with flexibility and fracture resistance, while the exterior layer of HFMBA-FEMC plays a role as a LiF reservoir to promote Li mass transfer and its even electrodeposition. In the meantime, some excess HFMBA and FEMC monomers further dissolve into the electrolyte as molecular additives, followed by in situ generation of a thin and robust LiF-rich cathode electrolyte interface (CEI). With the resulting Li anode, Li/NCM811 full cells showcase multifold cyclability amplification in comparison to cells using Bare-Li, covering durable cyclability with a capacity retention of 81.8% after 400 cycles. When the cutoff voltage is elevated to 4.5 V or the working temperature is elevated to 45 °C, the cells still maintain a stable operation for extending 300 cycles.

An eco-friendly strategy for emerging contaminants removal in water: Study of the adsorption properties and kinetics of self-polymerized PHEMA in green solvents

Water contaminants severely affect human health and aquatic ecosystems, and adsorption poses an economic, available, and feasible technology for remediation that needs to be accompanied by eco-friendly and sustainable materials. This study proposes an eco-friendly strategy for removing emerging contaminants using polyhydroxyethyl methacrylate polymers synthesized by self-polymerization with hydrophilic first-generation deep eutectic solvents. The polymers were characterized using structural and physical characterization techniques and their adsorption capacity against four emerging contaminants: a non-steroidal anti-inflammatory drug, an antibiotic, a pesticide, and a non-ionic surfactant. The experimental results showed high adsorption capacity for the urea: choline chloride-derived polymer with 6.21, 7.19, 6.01, and 6.99 mg⋅g-1 for paracetamol, ciprofloxacin, glyphosate, and triton X-100, respectively; these values are comparable to those obtained for similar systems. Kinetic, isothermal, and thermodynamics were also studied using various mathematical models to understand the adsorption mechanism, further complemented by DFT analysis. Chemisorption was found to be the primary mechanism by exothermic and ordered processes, which is thermodynamically favored. The study demonstrated for the first-time the effectiveness of self-polymerized PHEMA without chemical modification as a reusable adsorbent material and its ability to remove different types of emerging contaminants, thereby offering a promising solution for water treatment in environmental science.

Hyperbranched Organosilicon Surfactants as Emulsifiers for the Emulsion Polymerization of Methyl Methacrylate

This report is devoted to the investigation of the emulsion polymerization of methyl methacrylate in the presence of PEGylated hyperbranched polymethylethoxysiloxane as an emulsifier. It is shown that its use in the amount of 1–5 wt % affords stable 25–50% poly(methyl methacrylate) dispersions with the controlled particle sizes from 300 to 800 nm and a narrow particle size distribution.

Direct-through channels of ZIF-8 composite membranes via in-situ PolyBMA sealing: Radical-induced phase transformation and dye removal efficiency

Metal-organic frameworks (MOFs)-based hybrid composite membranes are promising candidates for achieving highly efficient water purification. In this study, a facile, novel pressure-induced filtration method involving in-situ polymerization of butyl methacrylate (BMA) was proposed for sealing ZIF-8 nanoparticles on top of polyethersulfone (PES) ultrafiltration membrane support. The developed (ZIF-8+polyBMA)/PES composite membranes with thin toplayers of <1 μm present attractive water permeance (up to 31 LMH/bar) and good rejection of Congo red (99.2 %) and Methylene blue (99.1 %). The ZIF-8 particles served as direct-through channels with superior separation performance due to their high porosity and tunable pore structure, while the interstices were successfully sealed with polyBMA by in-situ polymerization, as demonstrated by SEM and dye removal experiments. It was found that the morphology of ZIF-8 transformed from a rhombic dodecahedron to two-dimensional hexagonal nanosheets during the fabrication process. We hypothesize that this surprising phenomenon is caused by the reaction of the initiators (Na2S2O5 and K2S2O8) that generate the hydroxyl and sulfate radicals attacking and transforming the Zn-MIM bond network of ZIF-8. However, insights into the structural changes need to be further investigated to understand the mechanism involved.

Proton Transfer Anionic Polymerization of Methyl Methacrylate with Ligands for Dual Control of Molecular Weight and Tacticity

Proton Transfer Anionic Polymerization of Methyl Methacrylate with Ligands for Dual Control of Molecular Weight and Tacticity

Diffusion and Exchange Kinetics of Microparticle Formulations by Spatial Fourier Transform Fluorescence Recovery after Photobleaching with Patterned Illumination.

The mechanism of active pharmaceutical ingredient (API) mobility during release in microparticle formulation was investigated using periodically structured illumination combined with spatial Fourier transform fluorescence recovery after photobleaching (FT-FRAP). FT-FRAP applies structured photobleaching across a given field of view, allowing for the monitoring of molecular mobility through the analysis of recovery patterns in the FT domain. Encoding molecular mobility in the FT domain offers several advantages, including improved signal-to-noise ratio, simplified mathematical calculations, reduced sampling requirements, compatibility with multiphoton microscopy for imaging API molecules within the formulations, and the ability to distinguish between exchange and diffusion processes. To prepare microparticles for FT-FRAP analysis, a homogeneous mixture of dipyridamole and pH-independent methyl methacrylate polymer (Eudragit RS and RL) was processed using laminar jet breakup induced by vibration in a frequency-driven encapsulator. The encapsulated microparticles were characterized based on particle size distribution, encapsulation efficiency, batch size, and morphology. Utilizing FT-FRAP, the internal diffusion and exchange molecular mobility within RL and RS microparticles were discriminated and quantified. Theoretical modeling of exchange- and diffusion-controlled release revealed that both RL and RS microparticles exhibited similar exchange decay rates, but RL displayed a significantly higher diffusion coefficient. This difference in diffusion within RL and RS microparticles was correlated with their macroscopic dissolution performance.

Synthesis and properties of superhydrophobic monomer stearyl methacrylate-modified polyacrylate latex pressure sensitive adhesives

Hybrid surfactants of long carbon chain hydrophobic nonionic emulsifier N-390 and conventional anionic emulsifier CO-436 were utilized in this study to enable successful emulsion polymerization of super-hydrophobic monomer stearyl methacrylate (SMA) together with butyl acrylate (BA), acrylic acid (AA), and 2-hydroxyethyl acrylate (HEA). The influences of SMA on the resulting latex and film properties were thoroughly investigated. Both FTIR and 1H NMR were used to confirm the successful participation of SMA in the emulsion polymerization. The results indicated that with introduction of SMA, the roughness of the latex film increases, while the light transmission decreases. It was also found that with the addition of SMA, contact angle of the latex PSA film increased from 115.1° to 127.2°, while water absorption decreased from 5.76 to 2.89 wt%. DSC curves demonstrated that SMA has participated more in the homopolymerization reaction than in the copolymerization reaction. TGA results showed that the initial decomposition temperature (T5%) of the latex film was increased from 302.8 to 332.7 °C with the increase of SMA dosage from 0 to 20 wt%. Finally, adhesion properties results indicated that loop tack and 180° peel force of the PSA films were decreased from 11.51 to 1.88 N/25 mm and 6.36 to 3.44 N/25 mm, respectively, while shear strength was increased from 732 to 2865 min.

Living Cell-Mediated Catalyst-Free Spontaneous Polymerization of Zwitterionic Methacrylates for Preparation of Probiotic-Loaded Hydrogels.

Living cell-mediated polymerization offers promising applications in biomaterials, yet its further biological utilization is hindered by the need for metal ions or radical initiators with available methods. In this study, we introduce a living cell-mediated polymerization that leverages the intrinsic metabolic activities of living cells to initiate and sustain free radical polymerization of zwitterionic methacrylates. The polymerization proceeded in the absence of transition metal catalysts, radical initiators, or light sources. The conversion of zwitterionic methacrylate strongly correlated with cellular activities and achieved a maximum conversion of 98% within 48 hours. Living cells efflux redox power across membranes through metabolism and that terminal electron fluxes are captured by zwitterionic methacrylates pre-assembled on the living cell surface to initiate radical polymerization reactions. The polymerization caused significant changes to the cell membrane surface and synthesized hydrogels with tailored mechanical properties. The polymer hydrogel obtained via probiotic E. coli Nissle 1917 was able to release the in-situ encapsulated molecules, which demonstrated living cell-mediated polymer hydrogel as a vehicle for the delivery of both cellular and molecular therapeutic agents. This research offered a green and efficient method for synthesizing bioactive materials and advancing the field of cellular therapeutics and drug delivery.

Confining CsPbI3 perovskite in metal organic framework (MOF-545) as stable composite photocatalyst for efficient oxygen-tolerant NIR light-driven atom transfer radical polymerization

Zirconium-porphyrin metal-organic framework (MOF-545) encapsulated all inorganic iodide perovskite (CsPbI3) composite (CsPbI3@MOF-545) is used as highly efficient photocatalyst to catalyze NIR light induced atom transfer radical polymerization (ATRP). The combination of CsPbI3 and MOF-545 leads to a synergistic effect with enhanced photoinduced carrier separation and light absorption performance in the composite photocatalyst. The constructed CsPbI3@MOF-545(10 %) can efficiently catalyze the conversion more than 90 % of various monomers under 810 nm NIR light irradiation. Strong oxygen-resistance has been confirmed in the CsPbI3@MOF-545(10 %) catalyzed photo-ATRP system. In a large-volume photo-ATRP system (100 mL), the polymerization of methyl methacrylate (MMA) achieved a conversion over 90 % in 10 h using NIR light in air. The success of chain extension and block polymerization indicates good end-chain fidelity for the synthesized polymers. The composite photocatalyst still displays high photocatalytic activity for the synthesis of polymers with controllable dispersity after seven photopolymerization cycles, demonstrating its promising potential for practical applications.

Living Cell‐Mediated Catalyst‐Free Spontaneous Polymerization of Zwitterionic Methacrylates for Preparation of Probiotic‐Loaded Hydrogels

Living cell‐mediated polymerization offers promising applications in biomaterials, yet its further biological utilization is hindered by the need for metal ions or radical initiators with available methods. In this study, we introduce a living cell‐mediated polymerization that leverages the intrinsic metabolic activities of living cells to initiate and sustain free radical polymerization of zwitterionic methacrylates. The polymerization proceeded in the absence of transition metal catalysts, radical initiators, or light sources. The conversion of zwitterionic methacrylate strongly correlated with cellular activities and achieved a maximum conversion of 98% within 48 hours. Living cells efflux redox power across membranes through metabolism and that terminal electron fluxes are captured by zwitterionic methacrylates pre‐assembled on the living cell surface to initiate radical polymerization reactions. The polymerization caused significant changes to the cell membrane surface and synthesized hydrogels with tailored mechanical properties. The polymer hydrogel obtained via probiotic E. coli Nissle 1917 was able to release the in‐situ encapsulated molecules, which demonstrated living cell‐mediated polymer hydrogel as a vehicle for the delivery of both cellular and molecular therapeutic agents. This research offered a green and efficient method for synthesizing bioactive materials and advancing the field of cellular therapeutics and drug delivery.

Enhanced SWIR Absorption in PMMA‐Coated TiN‐Based Metamaterial

AbstractAchieving highly efficient absorption in the short wavelength infrared (SWIR) spectral region is crucial for advancing numerous technologies. SWIR absorption enhances energy harvesting in solar cells, improves the sensitivity of infrared sensors, and enables precise control of thermal radiative properties in thermal emission devices. These advancements are essential for applications such as thermal imaging, night vision, and thermophotovoltaic systems. The study presents a simple, cost‐effective design of a polymer‐coated multilayer perfect absorber (MPA) metamaterial optimized for the SWIR spectral region. The proposed MPA structure is composed of four distinct layers: a top layer made of polymethyl methacrylate (PMMA) polymer, a second layer featuring arrays of circular titanium nitride (TiN) disks, a dielectric middle layer consisting of a pure zinc oxide (ZnO) film, and a bottom metallic layer formed by a thin film of TiN. The results demonstrate that the MPA achieves near‐perfect absorption, with a remarkable 99% efficiency centered at a wavelength of 1.3 µm. The absorption properties are further investigated with respect to various structural parameters to ensure better performance of the absorber. These absorbers hold great promise for applications in energy absorption, infrared sensing, thermal emission, and related fields.

Corrosion protection performance of poly(PyM-co-GMA)/SWCNT nanocomposites coating on mild steel

Recently, there has been significant emphasis on developing electroactive functional methacrylate polymers for anticorrosive applications. In this context, we have synthesized Poly[(3,5-dimethyl-1H-pyrazole-1-yl) methyl methacrylate-co-glycidyl methacrylate] [Poly(PyM-co-GMA)] and its nanocomposite with single- walled carbon nanotubes (SWCNTs) [Poly(PyM-co-GMA)/SWCNT]. The resulting materials were characterized using Fourier Transform Infrared spectroscopy (FT-IR) and X-ray Diffraction analysis (XRD). Morphological changes due to the incorporation of SWCNTs were examined using field-emission scanning electron microscopy (FE-SEM) and high-resolution transmission electron microscopy (HR-TEM). The optical properties of Poly(PyM-co-GMA) and Poly(PyM-co-GMA)/SWCNT (0.5, 1.0, and 1.5 wt. %) were investigated. The thermal behavior of Poly(PyM-co-GMA) and its SWCNT nanocomposites was analyzed through thermogravimetric analysis (TGA). The anticorrosive performance of the prepared materials was evaluated on a mild steel substrate (MS) in a 3.5% (w/v) NaCl medium using electrochemical techniques. Results from potentiodynamic polarization and electrochemical impedance spectroscopy indicate that the Poly(PyM-co-GMA) and Poly(PyM- co-GMA)/SWCNT coatings (0.5, 1.0, and 1.5 wt. %) provide effective barrier protection for mild steel against marine environments.

Synthesis of Ultrahigh Molecular Weight Poly (Trifluoroethyl Methacrylate) Initiated by the Combination of Palladium Nanoparticles with Organic Halides

Ultrahigh molecular weight polymers display outstanding properties and have great application potential. However, the traditional polymerization methods have inevitable disadvantages that challenge the green synthesis of ultrahigh molecular weight polymers. The paper achieved an ultrahigh molecular weight poly (trifluoroethyl methacrylate) via a novel polymerization and discussed the mechanistic, kinetic, and experimental aspects. The combination of palladium nanoparticles with ethyl 2-bromopropionate has been identified as an exceedingly efficient system for initiating the polymerization of trifluoroethyl methacrylate. An ultrahigh molecular weight poly (trifluoroethyl methacrylate) with a number-average molecular weight up to 3.03 × 106 Da has been synthesized at a feeding molar ratio of [poly (trifluoroethyl methacrylate)]/[ethyl 2-bromopropionate]/[palladium nanoparticles] = 3.95 × 104:756:1 at 70 °C. The reaction orders concerning palladium nanoparticles, ethyl 2-bromopropionate, and poly (trifluoroethyl methacrylate) were determined to be 0.59, 0.34, and 1.38, respectively. By analyzing a series of characterizations, we verified that the polymerization of poly (trifluoroethyl methacrylate) was initiated by the ethyl 2-bromopropionate residue radicals, which were generated from the interaction between palladium nanoparticles and ethyl 2-bromopropionate. The comparatively large size of the palladium nanoparticles provided a barrier to chain-growing radicals, promoting the synthesis of ultrahigh molecular weight polymers.

Water‐Soluble, Spin‐Cast‐Based Crystalline Poly(Methacrylic Acid) Film as a Reversible Li‐Ion Battery Anode

Poly(methyl methacrylate) (PMMA) polymer anodes are proposed as potential reversible anode materials for lithium‐ion batteries (LIBs) owing to their simple thin‐film formation process and cost‐effectiveness. Nevertheless, challenges such as the use of toxic aprotic solvents and the irreversible consumption of Li ions during the initial cycle need to be addressed to improve their performance. Herein, a water‐soluble poly(methacrylic acid) (PMAA) polymer processed using a simple spin‐casting method as a reversible LIB anode is presented. Unlike the PMMA anode, the conjugated carbonyl groups of the crystalline PMAA polymer readily form a chain backbone during ex situ thermal annealing, demonstrating a reversible capacity. The mechanism underlying the superior electrochemical characteristics of the PMAA anode is revealed using grazing incidence X‐ray diffraction and theoretical calculations. In particular, the highly crystalline cyclic anhydride PMAA polymer induced by thermal annealing shows enhanced interactions between Li ions and CO groups during operation, resulting in improved electrochemical properties. The resulting crystalline cyclic anhydride PMAA anode achieves a capacity of ≈427.7 mAh g−1 and retains a reversible specific capacity of 156 mAh g−1 after 500 cycles, indicating that it is a promising polymeric anode for next‐generation LIBs.

One Reaction: Two Types of Mechanism-SARA-ATRP and SET-LRP-for MMA Polymerization in the Presence of PVC.

This study presents for the first time the polymerization of methyl methacrylate (MMA) in the presence of poly(vinyl chloride) (PVC) that takes place by both SARA-ATRP and SET-LRP mechanisms. The two types of polymerizations that occur in the system are PMMA grafting to the PVC backbone and the formation of a new PMMA polymer, both occurring in the presence of a Cu0wire. The polymerizations were controlled as confirmed by the molecular weight evolution, polymerization kinetics, and variations in the dispersity value. The MMA polymerization in the presence of PVC at 60 and 70 °C leads to the formation of two polymer species characterized by an increase in the molecular weight with the conversion and a narrowing of the dispersity value with the reaction progress. To increase the degree of control over the polymerization, the same reaction was performed at room temperature, which allowed us to highlight the presence of the SARA-ATRP and SET-LRP mechanisms via subsequent polymer chain extensions. The results demonstrated that PMMA grafting on PVC polymers follows a SARA-ATRP mechanism, while the formation of a PMMA homopolymer entails a SET-LRP process. The influence of solvent nature on the polymerization reaction was studied by performing the grafting of N-isopropylacrylamide (NIPAM) onto the surface of PVC particles in aqueous media in the presence and in the absence of CuCl2. The polymerization reactions and the obtained materials were studied by gel permeation chromatography (GPC), 1H NMR, DMA, scanning electron microscopy (SEM), and atomic force microscopy (AFM).

Enhanced antifouling and anti-swarming properties poly (sulfobetaine methacrylate-co-2-hydroxy-3-phenoxypropyl acrylate) hydrogel coatings for urinary catheters

Catheter-associated urinary tract infection (CAUTI) remains an unsolved challenge to date, particularly with the emergence and rapid spread of antimicrobial-resistant bacterial pathogens. Despite extensive research, a catheter coating that can offer intrinsic resistance to host protein deposition, bacterial biofilm formation, and swarming is still urgently required. Zwitterionic hydrogel coatings due to their superior lubricity and antifouling properties represent a promising candidate, but their weak mechanical stability in water and poor resistance to bacterial swarming migration limit their application in urinary catheters for infection control. In this research, we describe the fabrication of a multifunctional catheter coating by copolymerizing zwitterionic sulfobetaine methacrylate (SBMA) polymers and a swarming inhibitor material, 2-hydroxy-3-phenoxypropyl acrylate (HPA). The introduction of polyHPA (PHPA) effectively impeded the uncontrolled swelling behavior of the zwitterionic PSBMA hydrogel, resulting in enhanced mechanical stability. Moreover, the copolymer coating retains the antifouling and anti-swarming properties of the homopolymers when challenged with fibrinogen, Escherichia coli, and Proteus mirabilis. The HPA content significantly correlated with its anti-adhesion activity against fibrinogen and biofilm, and the coating with an SBMA: HPA monomer feed molar ratio of 4:1 showed the best antifouling activity, reducing fibrinogen deposition by about 40 % and biofilm coverage by around fourfold compared to the uncoated polydimethylsiloxane (PDMS) surface. Furthermore, the copolymer coating also exhibited no cytotoxicity, suggesting it as a promising catheter coating for preventing CAUTI.

Bioderived Thiol-Ene Emulsion Polymerization for Hybrid Latex Particles.

The thiol-ene emulsion polymerization of three dienes synthesized from bioderived compounds, and subsequent preparation of core-shell polymer latexes, is reported. Levoglucosan (LGA), levogucosenone (LGO) and isosorbide were first modified with 4-pentenoic acid to install polymerizable groups. These monomers were used along with a dithiol to prepare poly(thioether) particles via ab initio emulsion polymerization using potassium persulfate as initiator and sodium dodecyl sulfate as surfactant. The structure of the diene significantly influenced the size of the resulting polymer latex particles. Given their low glass transition temperature, the LGA-derived poly(thioether) particles were used as a seed for the seeded emulsion polymerization of either styrene or methyl methacrylate. Core-shell latex particles with a high Tg core and a low Tg bioderived shell were formed, as verified by electron microscopy and in agreement with theoretical predictions of the equilibrium particle morphology based on the interfacial tensions of each particle phase.

Functionalized Polyisobutylene and Polyisobutylene‐Based Block Copolymers by Mechanistic Transformation from Cationic to Radical Process

AbstractThe strategy for the preparation of polyisobutylene‐based block copolymers via mechanistic transformation from cationic to radical polymerization is reported. This strategy involves the synthesis of 2‐bromo‐2‐methylpropanoyl‐terminated difunctional polyisobutylene macroinitiator (BiBB‐PIB‐BiBB) via consecutive cationic polymerization, in situ preparation of hydroxyl‐terminated polyisobutylene and its acylation by 2‐bromo‐2‐methylpropanoyl bromide. The Mn2(CO)10−triggered photo‐induced radical polymerization of styrene in bulk using this macroinitiator leads to the formation of multiblock copolymer, while predominantly triblock copolymer is generated during the polymerization of methyl methacrylate. The possibility to functionalize the polyisobutylene by pyrene via photo‐induced radical addition of 1‐bromomethyl pyrene in the presence of Mn2(CO)10 is also demonstrated in this work.

Improving the mechanical, spectroscopic and laser ablation characteristics of UDMA-MMA copolymers using a titanocene photoinitiator

We have shown that the Irgacure 784 titanocene photoinitiator can be advantageously used to improve the light absorption, mechanical and nanosecond-regime laser ablation properties of urethane dimethacrylate (UDMA)-methyl methacrylate (MMA) polymer blends with photopolymerization using curing with green (520–525 nm) light. The hardness was found to be significantly higher (0.25–0.29 GPa) than that of other UDMA polymer blends photopolymerized using other initiator systems. The established 48–63 % degree of conversion is also comparable to that of similar other blends and is useful in many applications. The laser ablation and laser-induced breakdown spectroscopy (LIBS) properties of these polymers were studied at 266 and 532 nm laser wavelengths. The polymers showed consistently good laser ablation characteristics (reproducible, well-defined, shallow craters) at 266 nm wavelength, whereas at 532 nm, extensive carbonization and strong photothermal effects were observed. LIBS spectra of the blend shows lines of C, H, O, N and Ti as well as C2 and CN bands, but provide many spectral windows for interference-free analytical measurements. Our findings indicate that UDMA-MMA polymer blends can be good candidates as target matrices for laser ablation-based measurements in the UV or Vis range, in applications like analytical spectroscopy or laser-initiated fusion research.