Creams are semisolid dosage forms widely used for pharmaceutical and cosmetic purposes due to their pleasant appearance, easy spreadability, and the possibility to deliver hydrophobic and hydrophilic active agents. The aim of the current study was to evaluate the impact of type and concentration of different oil phases on the mechanical and rheological properties of cosmetic creams. For this purpose, a series of blank and anti-age creams were prepared applying the hot homogenization method (9000 rpm for 5 minutes). The blank creams contained an emulsifying base (Neofin Nat 8% w/w) and varying types of lipid phase: 1) babassu oil (8% w/w), 2) Cannabis sativa (2% w/w) and Camelina sativa (6% w/w) oils, 3) babassu (6% w/w) and Cannabis sativa (2% w/w) oils, and 4) babassu (6% w/w) and Camelina sativa (2% w/w) oils. The anti-age creams contained additionally Jasminum sambac flower extract (5% w/w) and Аrgireline® solution (5% w/w). The spreading, mechanical, and rheological properties of the developed formulations were investigated. The anti-age cream based on babassu (6% w/w) and Camelina sativa (2% w/w) oils exhibited suitable textural and rheological characteristics that would facilitate its application onto skin and provide sufficient contact time to exert its beneficial effects.
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