The largest carbonate condensate field in China has been found in the central Tarim Basin. Ordovician carbonate reservoirs are generally attributed to reef-shoal microfacies along a platform margin. However, recent production success has been achieved along the NE-trending strike-slip fault zones that intersect at the platform margin. For this contribution, we analyzed the strike-slip fault effects on the reef-shoal reservoirs by using new geological, geophysical, and production data. Seismic data shows that some NE-trending strike-slip faults intersected the NW-trending platform margin in multiple segments. The research indicated that the development of strike-slip faults has affected prepositional landforms and the subsequent segmentation of varied microfacies along the platform margin. In addition, the strike-slip fault compartmentalized the reef-shoal reservoirs into multiple segments along the extent of the platform margin. We show that fractured reef-shoal complexes are favorable for the development of dissolution porosity along strike-slip fault damage zones. In the tight matrix reservoirs (porosity < 6%, permeability < 0.5 mD), the porosity and permeability could be increased by more than 2–5 times and to 1–2 orders of magnitude in the fault damage zone, respectively. This suggests that high production wells are correlated with “sweet spots” of fractured reservoirs along the strike-slip fault damage zones, and that the fractured reservoirs in the proximity of strike-slip fault activity might be a major target for commercial exploitation of the deep Ordovician tight carbonates.