Platform Approach Research Articles

An observation of the ozone response to a magnetic cloud: A case study

At midlatitudes (40°-65°S), stratospheric ozone loss has been linked to a variety of physico-chemical effects. In this study, however, we examine how ozone responded to a fortuitous magnetic cloud (MC)-triggered storm on 20 November 2003 using a synthesis of multiple platform approach. We employed this approach to predict how energetic particles interact with the atmosphere by determining realistic NOx production rates without having to run a full ion chemistry model. Using simplified numerical approximations and synthetic satellite observations, we found that this method of ion pair production might be more economical in terms of numerical cost. Following three days of MC, the tendency for ozone reduction became apparent. According to this study, relativistic electron microbursts may promote particle precipitation, which in turn induced the occurrence of NOx around 55 km midlatitude. This corroborates the hypothesis that existing electron precipitation proxies, which do not yet take relativistic microburst energies into account, are likely overlooking a significant source of precipitation that affects atmospheric ozone levels.

POLITICAL CAMPAIGN STRATEGY OF PDIP IN SURABAYA ON INSTAGRAM AND FACEBOOK MEDIA

This study describes the important role of social media in politics in interacting with digital networks. Eri – Armudji further highlight the advantages of PDIP in order to gain promotional votes on Instagram and Facebook media with embedded text in various forms of campaign content to field implementation. PDIP brings Eri – Armudji as a leader in the City of Surabaya 2020-2024. This study uses descriptive qualitative, data collection through interviews, documentation, and observation. The theoretical approach uses Niffenegger’s political strategy of 4P (Product, Promotion, Prince, Place). Research results, First; shows that the success of PDIP Surabaya as a political party has a high correlation with figures, community members in increasing their popularity and electability through coalitions of parliamentary and non-parliamentary parties to the use of social media. One of them continues to introduce Eri – Armudji by carrying out campaign movements through the 4P strategy that has been proven to win the superior vote of 597,540 voters or 56.94% of political opponents. Second; Eri – Armudji’s political campaign during the pandemic used a candidate platform approach, humanist-religious, economic value, mass communication skills both in the field and in social media as a means of winning political campaigns online with of followers of Eri Cahyadi on Instagram 26,000 – Facebook 6,695, while followers Armudji on Instagram 19,700 – Facebook 1,205. So that social media has an effect on increasing victories of Eri Cahyadi and Armudji with a cross-party coalition strategy approach and strengthening the acquisition of parliamentary seats in the DPRD in the city of Surabaya.

How financial services leaders are using enterprise intelligence to optimise efficiency ratios

Digital transformation needs to focus not just on automation but on smarter, faster, more profitable decisions throughout the customer life cycle. This involves creating a unified decision management infrastructure that enables people throughout the bank to access and use enterprise intelligence. This paper shares nine ways to measure success in digital transformation and how seven leading banks realised improvements along these measures by taking a platform approach to decision management.

Development of the Ambulance 3.0 platform application

The article examines the application of the platform approach to solving the problem of optimizing the work of emergency medical services in the city of Yekaterinburg with a population of over a million. This project is especially relevant due to the ambulance operators and crews’ heavy workload associated with seasonal increases in the morbidity rate, the COVID-19 pandemic and other crisis situations. The goal of the study is to solve the aforementioned problems by means of developing a highly specialized but also functional service as well as ensure the possibility of using it in the post-pandemic era. The author of the article points out that current realities make it especially important to create such application because while relevant Russian studies do not pay proper attention to emergency medical services issues, the use of foreign counterparts is not possible for various reasons, including that of the large amount of confidential data that require processing. It is expected that in case the technical and software parts of the project are implemented successfully, the application described in the study will allow to achieve all the objectives set and ensure the improvement of the socio-economic situation of Yekaterinburg.

Toxicological Assessments of a Pandemic COVID-19 Vaccine-Demonstrating the Suitability of a Platform Approach for mRNA Vaccines.

The emergence of SARS-CoV-2 at the end of 2019 required the swift development of a vaccine to address the pandemic. Nonclinical GLP-compliant studies in Wistar Han rats were initiated to assess the local tolerance, systemic toxicity, and immune response to four mRNA vaccine candidates encoding immunogens derived from the spike (S) glycoprotein of SARS-CoV-2, encapsulated in lipid nanoparticles (LNPs). Vaccine candidates were administered intramuscularly once weekly for three doses at 30 and/or 100 µg followed by a 3-week recovery period. Clinical pathology findings included higher white blood cell counts and acute phase reactant concentrations, lower platelet and reticulocyte counts, and lower RBC parameters. Microscopically, there was increased cellularity (lymphocytes) in the lymph nodes and spleen, increased hematopoiesis in the bone marrow and spleen, acute inflammation and edema at the injection site, and minimal hepatocellular vacuolation. These findings were generally attributed to the anticipated immune and inflammatory responses to the vaccines, except for hepatocyte vacuolation, which was interpreted to reflect hepatocyte LNP lipid uptake, was similar between candidates and resolved or partially recovered at the end of the recovery phase. These studies demonstrated safety and tolerability in rats, supporting SARS-CoV-2 mRNA-LNP vaccine clinical development.

Microbial Carotenoid Synthesis Optimization in Goat Cheese Whey Using the Robust Taguchi Method: A Sustainable Approach to Help Tackle Vitamin A Deficiency.

The work describes the carotenoid synthesis process by Rhodotorula glutinis P4M422 using an agro-industrial waste as the substrate, seeking a biorefinery platform approach for waste utilization to produce high-value molecules. A culture medium based on goat milk whey (GMW) was optimized via the Taguchi method (L9 array). Four factors (ethanol, carbon and nitrogen source, and pH) were evaluated at three levels. The carbon and nitrogen composition were the factors dominating the process performance. Optimized conditions were validated (Urea, 0.3% w/v; pH, 4.5; ethanol, 10% v/v; glucose, 6.0%), and the carotenoid production (4075 µg/L) was almost 200% higher than when using the un-optimized process (2058 µg/L). Provitamin A carotenoids torulene, β-carotene, and γ-carotene (different proportions) were produced under all conditions. The hydrolyzed goat milk whey showed promising expectations as a low-cost source for carotenoid production by Rhodotorula glutinis P4M422. The results are important for the innovative sustainable production of carotenoid-rich matrices for different purposes (nutrition, health promotion, color) and industries (foods, nutricosmetics, nutraceuticals, feeds), notably to help to combat vitamin A deficiency.

Urban platform approach in Covid-19 pandemic management (case of Semarang and Yogyakarta, Indonesia)

The world population is experiencing urban life disruption since early 2020 due to the Covid-19 pandemic. In Indonesia, Semarang and Yogyakarta both are the capital cities of respective provinces, undergone the peak of pandemic twice. The first peak occurred between January and February 2021, and the second peak occurred in July 2021. The pandemic that occurred in those two cities altered the dynamics of urban social, political, and cultural dynamics. This paper attempted to discover the phenomenon of urban management in Semarang and Yogyakarta in dealing with the Covid-19 pandemic. In this study, statistical description was used by comparing indicators and investigating their relationship using urban platform approach. The study found four major variables in Semarang and Yogyakarta: the quality of the environment; collaboration and coordination among government, society, and private parties; the presence of infrastructure to deal with Covid-19; and pandemic handling in planning and implementation.

A human-centered IIoT platform approach for manual inspections: Towards digital documentation and assistance applications

Manual inspection processes’ results are difficult to map into digital twins. Since they rely on the expertise of the inspector and lack support systems, the process and the accompanying manual documentation are error-prone and time-consuming. This paper addresses this deficit, presenting an IoT-based platform approach to enable digitized and assisted inspections. Requirements for this platform are derived from process analyses in the aircraft domain and are addressed with the help of ISO's IoT reference system architecture based on adaptable solution modules. The focus is on the cross-application data model and the documentation module, enabling the mapping of the inspection process as a digital twin.

Strategic opportunities for the development of digital platforms of industrial companies

Industrial corporations are actively implementing digital technologies, which has an impact on the content of business models. The implementation of the platform approach is the main vector of strategic development of an industrial company. The platform approach changes the processes of industrial business modelling, which have an impact on competitiveness, and forms the leading positions of an industrial company in the market. Digital platforms are becoming the basis for the design of the technological chain, and business processes. The ecosystem nature of digital platforms contributes to the increase of business innovation activity. The functioning of the platforms is aimed at creating new values, implementing the concept of client-centricity, innovative development and the formation of competitive advantages. 36 technological platforms are used in Russia. The technological platform solves ecosystem tasks to ensure the functioning of the information and communication circuit of the digital ecosystem, which determines its strategic orientation.

Regional mechanism for sustainable development

Technologization and resource consumption of modern regional production complexes actualizes the paradigm of their sustainable development. Ecosystem development of mesoterritoriums requires the use of integrated approaches, the creation of conditions and incentives. The concept of using an integrated mechanism to achieve sustainable development of the region as a technology for managing the territorial economy, focused on improving the efficiency of territorial production complexes, the implementation of priority areas in science, technology and critical technologies is put forward. The components of the management tools for the sustainable development of mesosystems are proposed, representing the internal structure and sequence of stages of interrelated directions of movement of the territorial economy to the desired state. This mechanism can be considered as a set of actions, the implementation of which will lead to socio-economic progress at a new level. A comprehensive regional mechanism of sustainable development is substantiated, which activates the process of economic and social changes in five directions: economic, spatial, social, digital and environmental, ensuring the implementation of the strategy of transformational processes. The proposed integrated regional mechanism of sustainable development can be applied at different levels of territorial management. In the conditions of modern realities of the implementation of the new regionalism, it is advisable to ensure stable trends in territorial development on the basis of platform and ecosystem approaches.

ЦИФРОВЫЕ HR -ПЛАТФОРМЫ И ЭКОСИСТЕМЫ В ГОСУДАРСТВЕННОМ УПРАВЛЕНИИ

The global trend of digital transformation of public administration, the processes of its development in Russia have exposed the lack of modern personnel management technologies. The purpose of the article is to develop a conceptual framework for thinking about the platform and ecosystem approaches as tools to overcome the fragmentation of public sector workforce efforts. The research was based on the trends in the HR transformation of public administration, the basic definitions of digital HR platforms and ecosystems, and the emerging concepts of personnel management in the context of digitalization. The methods of content analysis, structural analysis, and a comparative method were used. As a result, the principles of building digital HR systems were identified, leading to an orderly and optimal interaction between participants, the parameters for building an advanced HR platform to provide a configuration that meets the modern needs of the state and civil servants, and success factors for creating digital HR ecosystems. The article was prepared as part of the research work of the state task of the RANEPA.

Multistakeholder Collaboration to Enhance the Scalability of Jarwo Super Technology: An Innovation Platform Perspective

<p align="justify">The process of accelerating the diffusion of research and development (R&D) results in an agricultural innovation system (AIS) can be realized through an innovation platform approach. This study examines the collaboration of multi-stakeholders in the process of development and diffusion of the Jajar Legowo (Jarwo) Super technology through the perspective of innovation platform. There have been few studies in the area to look at the structure of technology diffusion process to achieve a scalability of impact. This study will fill the gap by looking at the structure of multi-stakeholders’ network and the working mechanism of the platform to get understanding on the delivery process of Public Research Organization (PRO)’s research result at a systemic level. The analysis of this research is equipped with the application of a co-word analysis. This tool is used to map issues based on the actor's function, namely the role in the development and diffusion of Jarwo Super technology. The results of the study will contribute to the theoretical development of innovation platform in AIS. It also provides a basis for policy makers and related stakeholders on how innovation platform can strengthen agricultural development programs in a wider organizational context.</p>

The conception of the digital platform of independent assesment of the future teachers

Introduction. Modern processes of digitalization of education put forward new requirements for the procedures for evaluating the results of research results of research results of teachers. Of particular relevance are approaches to the design of digital research tools, including electronic resources that allow consolidating the consumption and evaluation of the educational result by experts with the possibility of implementing an integrative and differentiated evaluation procedure. Materials and Methods. Methods of analysis, systematization and generalization of scientific literature on problematic studies were used. The purpose of the article is to analyze and substantiate the conceptual foundations for creating a digital platform for an independent assessment of the level of achievement of research results by future teachers. Results. The article analyzes approaches to the protection of electronic resources in the fields of education, substantiates the advantages and functionality of the phenomenon of electronic assessment. The conceptual foundations for creating digital platforms are the methodological unity of the platform and ecosystem approach, extended methodological assessments of the foundations for creating an independent educational result system, including systemic, activity-based, criteria-based, competency-based, technological, level-based approaches, objectivity, objectivity, reliability and openness of assessment procedures. The digital platform for independent assessment of the level of achievement of the educational result gives its idea based on the evaluation of the effectiveness of the study of results, the effectiveness of data and their use on the basis of broad procedures and algorithms for assessing the educational result of the observation of teachers, the modularity of the organization of procedures for assessing the educational result, non-linear functionality, partisipatory analytics and evaluation of results , popular results at the lowest cost of resources. The digital platform for independent assessment of the level of achievement of the educational result performs an analytical, predictive, evaluation, information and aggregation function. Discussion and Conclusions. As part of the study of the conceptual and practice-oriented statistical foundations for independent evaluation of the results of teacher research, promising areas for long-term research have been identified: – adding a digital platform for independent evaluation of the results of teachers' observation in the system of teachers' professional growth, accompanying young professionals in the life cycle of the profession; – improvement of the university accreditation system based on the use of a digital platform; – determination of approaches to the combination of emotional, psychological comfort and personality verification processes in the procedures for implementing the evaluation of research results.

Cost-efficient digital twins for design space exploration: A modular platform approach

The industrial need to predict the behaviour of radically new products brings renewed interest in how to set up and make use of physical prototypes and testing. However, conducting physical testing of a large number of radical concepts is still a costly approach.This paper proposes an approach to actively use digital twins in the early phases where the design can be largely changed. The approach is based on creating a set of digital twin modules that can be reused and recomposed to create digital twin variants. However, this paper considers that developing a digital twin can be very costly. Therefore, the approach focuses on supporting the decisions about the optimal mix of modules, and about whether a new digital twin module should be developed.The approach is applied to an industrial case derived from the collaboration with two space manufacturers. The results highlight how the design of the modular platform has an impact on the cost of the digital twin, if commonality and reusability aspects are considered. These results point at the cost-efficiency of applying a modular approach to digital twin creation, as a means to reuse the results from physical testing to validate new designs and their ranges of validity

Nontargeted metabolomic analysis of four different parts of Actinidia arguta by UPLC-Q-TOF-MSE

Actinidia arguta, an edible berry plant with high nutritional values, has been widely used in Asian countries as a food and traditional medicinal herb. The well-recognized health-promoting properties of A. arguta were associated with its bioactive components in its different botanical parts. To rapidly screen and identify chemical components and simultaneously determine the potential metabolites from different parts of A. arguta, UPLC-Q-TOF-MSE coupled with UNIFI platform and multivariate statistical analysis approach was established in this study. As a result, a total of 107 components were identified from the four different parts of A. arguta, in which 31 characteristic chemical markers were discovered among them, including 12, 8, 6, and 5 compounds from the fruits, leaves, roots, and stems, respectively. These results suggested that the combination of UPLC-Q-TOF-MSE and metabolomic analysis is a powerful method to rapidly screen characteristic markers for the quality control of A. arguta.

Advancing the Contributions of European Stakeholders in Farming Systems to Transitions to Agroecology

SummaryThe concept of a ‘just transition’ is gaining traction in international policy discourses. It has particular significance in relation to achieving net zero greenhouse gas emissions and the need for ensuring rights and responsibilities of all actors in transitions to agroecological farming systems. Research plays an important role in accompanying this transformation. It explores pathways for more sustainable and fair food systems, barriers to them being achieved, and where and what risks arise for communities of interest and of place. Researchers and practitioners across levels and sectors were brought together in H2020 projects LIFT and UNISECO using processes of stakeholder engagement. Both projects analysed the perceptions of actors towards agroecological farming, and their active involvement in the transitions required. This article summarises lessons learnt regarding multi‐actor engagement in different participatory settings in both projects, including a Multi‐Actor Platform approach, Q method, DELPHI and Hybrid forum workshops. The interactions involved several hundred actors from 18 countries across Europe. The article reflects on implications of the Covid‐19 pandemic on the processes and effectiveness of multi‐actor engagement, and assessments of the impacts on the empowerment of the actors. The findings are contextualised by contemporary European Union and national policy objectives of tackling climate change, the loss of biodiversity, and inequalities.

Surveying cliff-nesting seabirds with unoccupied aircraft systems in the Gulf of Alaska

Drones, or unoccupied aircraft systems (UAS), can transform the way scientific information on wildlife populations is collected. UAS surveys produce accurate estimates of ground-nesting seabirds and a variety of waterbirds, but few studies have examined the trade-offs of this methodology for counting cliff-nesting seabirds. In this study, we examined how different UAS survey parameters might influence seabird counts for population monitoring and assessed behavioral responses to aerial surveys for three sub-Arctic seabird taxa in the Gulf of Alaska: common murres (Uria aalge), black-legged kittiwakes (Rissa tridactyla), and pelagic and double-crested cormorants (Phalacrocorax pelagicus and Phalacrocorax auritus). We flew two commercially available models of UAS in planned approaches at different speeds and distances from colonies during incubation and chick-rearing periods. We compared counts from UAS-derived images with those from vessel-based photography and assessed video recordings of individual birds’ behaviors for evidence of disturbance during UAS operations and control phases. Count estimates from UAS images were similar to or higher than those from conventional vessel-based images, and UAS were particularly effective at photographing birds at sites with high cliff walls or complex topography. We observed no significant behavioral responses to the UAS by murres or cormorants, but we did observe flushing by black-legged kittiwakes during UAS flights; most of these birds were not incubating or brooding. At both the colony and individual level, we observed slightly greater responses to the smaller UAS platform and closer approaches. These results inform both species specific and general best practices for research and recreational usage of UAS near cliff-nesting seabird colonies.

Who wants to go first? A simulation study of accrual in a stand-alone trial versus starting a platform trial

Others have quantified the efficiency of the platform approach as compared to a sequence of independent two-arm trials and have shown the platform approach more efficiently evaluates a set of candidate therapies. However, a practical barrier to initiating a platform trial is incentivizing the first candidate therapies to enter the platform. A platform trial is more complex and will take longer to design and operationalize than a traditional trial. For the first therapy, this additional up-front planning time must be considered along with the ability to enroll. There is a common concern that accrual in a platform setting would take longer than for a single stand-alone trial because intuition suggests that a two-arm trial with a smaller total sample size should complete accrual more quickly than a multi-armed trial. We focus on the accrual duration for the first therapy as a particular barrier to initiating a platform trial strategy. We simulate accrual into a platform trial versus a stand-alone trial in the setting of a large clinical trial network. Accrual duration in the platform strategy dominates that of a single stand-alone trial if the platform leverages a large enough fraction of the site network. Patient preference for a particular stand-alone trial has little impact on the ability of a stand-alone trial to enroll more quickly.

Physics-Based Circuit Modeling of the Impedance Characteristics of a Smart Hydrogel-Actuated Bending Sensor.

Smart hydrogels are stimuli-responsive polymers which exhibit a volume-phase transition in response to external influences. This makes them promising candidates for sensing elements, especially in a biomedical context due to their easily achievable biocompatibility. The main challenge in harnessing the smart polymer's potential for sensor applications lies in a reliable transduction of the swelling change into an electrical signal. A novel platform approach is based on a bending sensor where the smart hydrogel acts as an actuator on a thin film with embedded metal traces. Mechanical deformation due to the hydrogel volume change alters the traces' electric impedance. However, besides deformation, the medium surrounding the sensor structure will also affect the impedance. For sensor design it is therefore crucial to understand the complex interdependencies between electric sensor properties, influences of the surrounding medium and mechanical deformation. Here, an electric circuit model is presented which considers all these contributions through a minimum number of lumped elements and is strictly based on physical considerations. By employing measured impedance spectra from an experimental sensor implementation subjected to different surrounding media and mechanical deformation, the validity of the simplified model is demonstrated. A detailed analysis and discussion give insights into the determination of the different model parameters and how external influences can clearly be attributed to specific circuit elements. This work provides a general approach for deducing minimalistic but strictly physics-based circuit models which can still adequately replicate the actual behavior of such types of impedance-based bending sensors.

Network design. Using a platform approach and network cooperation in housing design, formation & revitalization of a living environment – participation, complexity approach

Networked methods of cooperation, informatization practices, decentralized systems, «Uberization», emerging today in “common” sectors of the economy, can have an effect in housing/renovation. The 20th century, to solve the problems of large-scale housing creation, formed its own systems (including mass-production, standardization, functionalist vision, typization, etc.)- they all complemented each other and gave a complex effect in synthesis. Today, for new problems of renovation & creating sophisticated environment, we can mark possibility of forming our own complex systems – including “new” economy, network production, collaboration of participants - creating its own tools, more adapted to solve new problems. Changes of the 21st-century: “new economy”, network cooperation & participation for creating environment (sophisticated distribution design tasks in networks), new management - can form new systems and design techniques that contribute to the individualization & new understanding of housing for 21-stage-society. An experimental platform was created on the basis of these ideas, allowing to synthesize them. 3 cases will be considered: 1-”contrasted”(with the traditional methodology) dwelling design with communities in IT-environment. 2-Experimental residential complex including a “game” with different forms of individualization. 3-A historical building, renovated into a mixed-use-development with a public park. All of them demonstrate complicity, usage of AI, IT & based on the open-building philosophy. The methodology of work includes theoretical models & real community testing, systematized information, methods classification, various digital modeling data.