Plant Resins Research Articles

Ethnotaxonomy and Ethnobotanical Studies of Honey and Resinous Plants in the Tchamba Prefecture in Togo

Natural plant products have gained increasing attention, but climate change and human activities have led to the degradation of ecosystems and loss of biodiversity. This study aims to contribute to the preservation of local knowledge related to the classification and use of honey-producing and resinous plants in the Tchamba prefecture, Togo. Ethnotaxonomic and ethnobotanical data were collected through semi-directed interview and focus groups in the four localities, involving 92 respondents. A total of 96 plants of beekeeping were identified, classified into 88 genera, 33 families, and 22 orders, with 16 ethnotaxonomic criteria used for classification. The most common criteria were "plant use" and "plant habit". The study highlights the rich local knowledge of plant uses for food, medicine, and rituals, emphasizing the importance of conserving both biodiversity and cultural heritage. These findings contribute to understanding how indigenous knowledge can support conservation and sustainable use of plant resources.

Potential Antitumor Mechanism of Propolis Against Skin Squamous Cell Carcinoma A431 Cells Based on Untargeted Metabolomics.

Propolis is a sticky substance produced by honeybees (Apis mellifera) through the collection of plant resins, which they mix with secretions from their palate and wax glands. Propolis can inhibit tumor invasion and metastasis, thereby reducing the proliferation of tumor cells and inducing cell apoptosis. Previous research has shown that propolis has an inhibitory effect on skin squamous cell carcinoma A431 cells. Nevertheless, its inhibitory mechanism is unclear because of many significantly different Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways between the ethanol extract of the propolis (EEP) group and the control group of cells. In this study, the main components of EEP and the antitumor mechanism at an IC50 of 29.04 μg/mL EEP were determined via untargeted metabolomics determined using ultra high-performance liquid chromatography tandem mass spectrometry (UHPLC‒MS/MS), respectively. The results revealed 43 polyphenolic components in the EEP and 1052 metabolites, with 160 significantly upregulated and 143 significantly downregulated metabolites between cells treated with EEP and solvent. The KEGG enrichment results revealed that EEP significantly inhibited A431 cell proliferation via the steroid hormone biosynthesis and linoleic acid metabolism pathways. These findings may provide valuable insights for the development of targeted therapies for the treatment of cutaneous squamous cell carcinoma.

Structure-Activity Relationship of Natural Dihydrochalcones and Chalcones, and Their Respective Oxyalkylated Derivatives as Anti-Saprolegnia Agents.

Saprolegnia sp. is a pathogenic oomycete responsible for severe economic losses in aquaculture. To date, there is no treatment for its control that is effective and does not pose a threat to the environment and human health. In this research, two dihydrochalcones 1 and 2, and three chalcones 3-5, isolated from the resinous plant Adesmia balsamica, as well as their synthesized oxyalkylated derivatives 6-29 already reported and a new synthesized series of oxyalkylchalcones 30-35, were evaluated for their anti-saprolegnia activity and structure-activity relationship as potential control and treatment agents for strains of Saprolegnia parasitica and S. australis. Among the molecules tested, natural 2',4'-dihydroxychalcone (3) and new oxyalkylchalcone 34 were the most potent antisaprolegnia agents against both strains, even with better results than the commercial control bronopol. On the other hand, the structure-activity relationship study indicates that the contributions of steric and electrostatic fields are important to enhance the activity of the compounds, thus the presence of bulky substituents favors the activity.

Chemical characterization of the hydrophilic fraction of (geo)propolis from brazilian stingless bees

Stingless bees make propolis and geopropolis; the latter is characterized by the presence of small portions of soils besides the usual plant resins. These propolis are consumed by rural and indigenous communities to heal or prevent diseases and have complex chemical composition; then to get a full understanding of their chemicals it is necessary the use of complementary analytical tools. Herein the hydrophilic fraction of 50 samples of Brazilian (geo)propolis (this way referring to either propolis or geopropolis from stingless bees) was derivatised and analysed by GC-MS. Therefore, the presence of semi-volatile and non-volatile compounds belonging to chemical classes such as flavonoids, esters, terpenoids, phenolic compounds, organic acids, phenylpropanoids, fatty acids, fatty acyls, and other lipids was confirmed. Exploratory multivariate analysis indicated that bee species affects the chemical composition of (geo)propolis. It was observed that (geo)propolis from Tetragonisca angustula from the states of Paraná and São Paulo have similar chemical composition suggesting that in both regions this stingless bee have gathered similar vegetal resins to make its (geo)propolis. Alternatively, Melipona quadrifasciata and Melipona marginata have generalist collection patterns as their (geo)propolis show a variable composition depending on the geographical origin.

Facile route for processing natural polymers for the formulation of new low-cost hydrophobic protective hybrid coatings for carbon steel in petroleum industry

This research helps with the creation, assessment, and characterization of a new hybrid protective coating for carbon steel alloy in acid conditions. The findings of this study will be useful for both chemical and petrochemical companies as well as scientists. This study aims to protect C-steel in acid pickling solution 1.0M HCl and formulate new hydrophobic protective hybrid organic–inorganic coatings from biopolymers chitosan and plant resin guar gum. Eight coating samples of chitosan in the absence and the presence of guar gum, silica and two heterocyclic compounds are prepared at feasible operational conditions using hot melt method. The aiding additives improved compatibility between coating constituents as confirmed by using different methods of analysis. This new processing approach has addressed the problems of using chitosan in corrosion control such as solubility in acid media and low mechanical strength. Coating samples of chitosan and its composites with the heterocyclic compounds (2-Hydrazinyl-6-methyl-4, 5-dihydro pyrimidine-4-on) or (2-Hydrazinyl-6-phenyl-4, 5-dihydro pyrimidine-4-on) are potent biocides. Coating shifts corrosion potential of carbon steel by 30 mV to more noble direction relative to the active potential 520 mV of bare carbon steel surface. Impedance and polarization measurements indicate that coating samples protect metal surface as mixed-type inhibitor by adsorption mechanism. There is a good agreement between percentages protection %P of coating calculated using the values of charge transfer resistance, Rct, and corrosion current density, icorr. All %P values are above 99% for all coating samples. Guar gum plant resin increases gloss of the coating film. Silica fills the pores in the polymeric film and increases the stuffiness of the polymeric coating film by modifying the particle size. All coated samples have high contact angle ranging from 150° to 165° indicating low wettability and high hydrophobicity of coating film on the metal surface.

Comparing Antimicrobial Effects of Heterotrigona itama Propolis from Two Regions of Malaysia Against Enterococcus faecalis

Objective: This present study aimed to determine and compare the antimicrobial properties of Malaysian propolis (MP) produced by Heterotrigona Itama from different regions of Malaysia, against E. faecalis. Methods: The propolis were obtained in Lenggong MLP (North Peninsula Malaysia) and Raub MRP - (Central Peninsula Malaysia). The antibacterial activities of the ethanolic extracts of propolis were conducted using antimicrobial susceptibility test (AST), minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The effect of these extracts on the cell morphology were observed using scanning electron microscopy (SEM). Calcium hydroxide and 5% dimethyl sulfoxide (DMSO) were used as controls. Results: Statistical analysis was done using unpaired t-test to differentiate the difference of the two averages. The ethanol extracts of MLP showed higher activity compared to MRP at 50mg/ml on E. faecalis with zone of inhibition of 14.33mm and 10.00mm respectively. MIC test for MRP and MLP was 0.78125mg/ml and 3.125mg/ml respectively. Whereas the MBC value for both MRP and MLP was 12.50mg/ml and 50.00mg/ml respectively. SEM analysis showed that MP disrupted the size, cell morphology and the structure of the bacteria cell wall. Conclusion: Our study showed MRP outperformed MLP against E. faecalis via MIC, MBC and SEM. Dissimilarities of surrounding trees in Raub and Lenggong may provide the variable chemical source contributing to this contrast. Thus, these stingless bees have a very special relationship with plant resins, relying on them for the very survival of their nests.

Characterisation of New Zealand Propolis from Different Regions Based on Its Volatile Organic Compounds.

Propolis is a bee product mainly consisting of plant resins and is used by bees to maintain the structural integrity of the colony. Propolis is known to contribute to bee health via its antimicrobial activity and is a valued product for human use owing to its nutritional and medicinal properties. Propolis is often characterised into seven categories depending on the resin source. New Zealand propolis is typically assumed as being poplar-type propolis, but few studies have chemically characterised New Zealand propolis to confirm or reject this assumption. Here, for the first time, we characterise propolis originating from different regions in New Zealand based on its volatile organic compounds, using gas chromatography coupled with mass spectrometry (GC-MS). To support this characterisation, we also collected and analysed resin samples from a variety of resin-producing plants (both native to New Zealand and introduced). Our findings suggest that bees mainly use poplar as a resin source, but also utilize native plant species to produce propolis. While regional variation did not allow for clear separation between samples, some patterns emerged, with samples from some regions having more chemical complexity and a higher contribution from native species (as suggested by a higher number of compounds unique to native species resin). Further studies are needed to accurately identify the botanical sources contributing to these samples. It may be also of interest to explore the biological activity of regional propolis samples and their potential nutritional or medicinal benefits.

New approach for processing chitosan as low cost protective hybrid coating for C-steel in acid media

The novelty of this study is that it the first time blending and formulation of chitosan as a new hybrid (organometallic) protective coatings for achieving synergistic protection for carbon steel alloy during acid pickling. The role of coated silica (by 0.1 wt % stearic acid lubricant) in the improvement of coating performance was highlighted. Variable weight percentage of chitosan and silica in addition to a fixed weight percentage (35 %) of guar gum natural plant resin, 5 × 10−6 mmol (2-Hydrazinyl-6-methyl (or phenyl) −4, 5-di-H pyrimidinone) as organic corrosion inhibitors were compounding as hot melt in the presence of a low cost surfactant as an emulsifying agent improved compatibility between coating constituents. Guar gum increased coating flow during application and grafted chitosan into high molecular copolymer resin insoluble in acid media. Phosphorous acid improved coating flexibility during application by hot dipping. Hybrid coating decreased corrosion potential of carbon steel and retarded both redox reactions of corrosion acting as adsorbed mixed-type inhibitor. Percentages protection (%P) approached hundred percentage as confirmed from the agreement between impedance and polarization parameters. Guar gum plant resin and slice powder increased gloss of coating. The coated silica filled the pores and increased stiffness of coating. Super hydrophobicity of coating was confirmed by the measured contact angle above 150oC indicating good spreading of coating sample as insulating adherent surface film.

Contribution to the knowledge of the nesting biology of Eumenine wasps (Hymenoptera, Vespidae) in the Brazilian Amazonia

ABSTRACT Several recent studies have improved our knowledge on the biodiversity and evolution of Eumeninae wasps, yet many groups lack systematic reviews, and there are still many gaps regarding the nesting biology, with the rather fragmentary information dispersed in the literature. Eumeninae are solitary wasps and important predatory insects regulating arthropod populations and exhibiting remarkable nest-building behaviors. Nesting strategies include using preexisting cavities, making clay pots, or other exposed structures built with plant material, sometimes incorporating chewed leaves, cellulose pulp, or plant resins. Understanding the nesting biology of Eumeninae is important for elucidating the origins of group living and eusociality, as these species range from solitary to primitively social. However, there is a scarcity of information on behavior and nest architecture, hindering a comprehensive understanding of these subjects. In this study, we describe and illustrate for the first time the nest of Monobia funebris Gribodo, 1891 (Odynerini), the nest of Eumenes versicolor de Saussure, 1852 (Eumenini), and provide additional information on the nesting of Pachymenes ghilianii (Spinosa, 1851) (Eumenini) from nests collected in the Brazilian Amazonia. Our observations reveal new facts about nest architecture in Eumeninae and highlight the need for additional efforts to elucidate aspects of the nesting behavior of M. funebris and the continued presence of female P. ghilianii in the nest after its completion.

Phytochemical potential and GC–MS analysis of propolis from Punjab region of India

Propolis is a beehive product produced from honeybees by mixing β-glycosidase enzyme and beeswax with exudate collected from plant resins. The main goal of this study was to investigate the phytochemical potential and GC–MS profiling of the main constituents of propolis. The antioxidant activity was assessed by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, total phenolic content and total flavonoid content were analysed by Folin-Ciocalteu reagent method and aluminium chloride method respectively. Methanolic extract exhibited highest antioxidant activities, ethanolic extract had the highest total phenolic content, and maximum amount of flavonoid was observed in the chloroform extract. GC–MS analysis revealed the presence of flavonoids, fatty acids and phenolic compounds. Results revealed that propolis from Derra Bassi can be used as natural antioxidant, also extracting solvents had a significant impact on the phytochemical activities and with its standardisation can be used for prevention of diseases related with free radicals.

Kuraray plans barrier resin plant

Kuraray plans barrier resin plant

Jute Fiber Reinforced Biocomposite: Towards Developing Composite Bone Plate

Bone fractures are often treated with metallic bone plates which are inherited some fundamental issues such as stress shielding, bone atrophy, heavyweight, corrosion, and so on. This work aims to develop a jute epoxy composite to investigate its feasibility to use as a composite bone plate. In this work, the natural fiber-based composite made of jute extracted from the jute plant and epoxy resin obtained from LAPOX® METALAM - B is studied experimentally. The mechanical properties such as tensile, compressive, and bending strength of jute/epoxy composite were measured using the universal testing machine (UTM). Moisture absorption test and scanning electron microscope (SEM) image analysis were also performed. The preliminary results suggest that the jute/epoxy composite could be a potential material for a composite bone plate. However, further detailed studies are required to confirm its applicability as a composite bone plate.

Removal of microparticles from hydrogenated oil by a microchannel separation coupling hydrocyclone: Industrial application

Separation techniques utilized in industrial manufacturing account for approximately 10–15% of the total global energy consumption. Energy-efficient separation has been made possible through the use of deep filtration technology. Herein, a novel continuous and regenerative microchannel separator coupled with a hydrocyclone was proposed. The microchannel separator, which had a processing capacity of 30 t/h, was constructed in a petroleum resin plant. This device could separate trace microfine particles in hydrogenated oil. After treatment with the microchannel separator, the average particle removal efficiency was 50.7%, and the turbidity of the hydrogenated oil was reduced by a maximum value of 60.9%. The removal efficiencies of pollutant particles with diameters smaller than 5 μm, in the range of 5–10 μm, and larger than 10 μm in the hydrogenated oil were 44.0%, 54.9%, and 75.9%, respectively. The processing load on the downstream diatomite filter was effectively reduced by the microchannel separator. The lifespan of the diatomite filter increased by 2.3 times compared to its initial value. Hazardous waste emissions decreased from 104 tons/year to 58.5 tons/year. The microchannel separator could be used not only for separating trace fine particles from liquids but also for separating oil and water by modulating the hydrophilic and hydrophobic properties of the particle surfaces.

Painting on the margins: investigating the pigments, media, and techniques of Séraphine Louis

The richly decorative and imaginative works by French artist Séraphine Louis (1864–1942) have long elicited fascination, and her working methods have often eluded art historians and conservators alike. Working in secret and outside established art circles, Séraphine employed materials such as natural resin varnishes and was said to have used household paints in addition to traditional artists' oil paints. In this study of six works in the collections of the Musée d'Art et d'Archéologie, Senlis (MAA), The Museum of Modern Art, New York (MoMA), and The Metropolitan Museum of Art, New York (MMA), attention was given to Séraphine's choice of colors and paints, in addition to identifying possible additions to or manipulations of painting media by the artist. Technical imaging was carried out using UVF to visualize the extent of Séraphine's use of natural resins. Analysis of the palette relied on XRF techniques and limited sampling for analysis by Raman and µ-FTIR spectroscopies. Overall, the following pigments were identified: lead white, zinc white, carbon-based black, red and brown ochres, umber, vermilion, alizarin lake, rhodamine B lake, Prussian blue, cobalt blue, ultramarine blue, chrome green, emerald green, viridian, cadmium yellow, and lead chromates, including chrome yellow deep and light, zinc yellow, and chrome orange. THM-Py-GCMS analysis of selected samples supported the documentary evidence of Séraphine's use of household oil paints; a single instance of a cellulose nitrate enamel paint was additionally determined by µ-FTIR. The chromatographic analysis also indicated a natural plant resin in her varnishes, probably dammar in combination with pine resin. Overall, this material investigation, accompanied by the art historical record, better reveals the techniques of an experimental painter whose works have come to epitomize French outsider artists of the early twentieth century.

An Aspergillus flavus strain from bee bread of the Western honey bee (Apis mellifera) displays adaptations to distinctive features of the hive environment.

Aspergillus fungi are ubiquitous inhabitants of colonies of the western honey bee (Apis mellifera), where they interact with bees in associations ranging from parasitism to possible mutualism. Aspergillus Flavi fungi are frequently found in bee bread (pollen processed for longterm storage) and are thought to contribute to food preparation, processing, preservation, and digestion. Conditions in the hive are challenging for fungi due, in part, to xeric and acidic properties of bee bread and the omnipresence of propolis, an antimicrobial product manufactured by bees from plant resins. We used quantitative and qualitative assays to determine whether A. flavus isolated from bee bread demonstrates tolerance for hive environmental conditions in terms of temperature, pH, osmotic pressure, and propolis exposure. Comparisons made use of three strains of A. flavus: a fungal biocontrol product not known from beehives (AF36), a strain isolated from bee bread (AFBB) in hives from central Illinois, and a pathogenic strain from a honey bee colony displaying symptoms of stonebrood (AFPA). Strain AFBB displayed higher tolerance of acidic conditions, low matric potential (simulating xeric substrate), and propolis exposure than did other strains. A genomic comparison between this new strain and the reference NRRL-3357 showed that AFBB, like AF36, might be blocked from carrying out aflatoxin biosynthesis. Sequence comparisons also revealed several missense variants in genes that encode proteins regulating osmotolerance and osmotic pressure in Aspergillus spp., including SakA, SskB, GfdA, and TcsB/Sln1. Collectively, results of our laboratory assays and genetic analyses are consistent with the suggestion that the strain isolated from bee bread is adapted to the bee bread environment and may have persisted due to a coevolutionary relationship between Aspergillus and A. mellifera. This finding bolsters recent concerns about the effects of fungicide use near bee colonies and broadens the ecological importance of highly adaptable fungal strains.

Thinking inside the box: Restoring the propolis envelope facilitates honey bee social immunity.

When wild honey bee colonies (Apis mellifera) nest in hollow tree cavities, they coat the rough cavity walls with a continuous layer of propolis, a substance comprised primarily of plant resins. Studies have shown that the resulting "propolis envelope" leads to both individual- and colony-level health benefits. Unfortunately, the smooth wooden boxes most commonly used in beekeeping do little to stimulate propolis collection. As a result, most managed bees live in hives that are propolis-poor. In this study, we assessed different surface texture treatments (rough wood boxes, boxes outfitted with propolis traps, and standard, smooth wood boxes) in terms of their ability to stimulate propolis collection, and we examined the effect of propolis on colony health, pathogen loads, immune gene expression, bacterial gene expression, survivorship, and honey production in both stationary and migratory beekeeping contexts. We found that rough wood boxes are the most effective box type for stimulating propolis deposition. Although the use of rough wood boxes did not improve colony survivorship overall, Melissococcus plutonius detections via gene expression were significantly lower in rough wood boxes, and viral loads for multiple viruses tended to decrease as propolis deposition increased. By the end of year one, honey bee populations in migratory rough box colonies were also significantly larger than those in migratory control colonies. The use of rough wood boxes did correspond with decreased honey production in year one migratory colonies but had no effect during year two. Finally, in both stationary and migratory operations, propolis deposition was correlated with a seasonal decrease and/or stabilization in the expression of multiple immune and bacterial genes, suggesting that propolis-rich environments contribute to hive homeostasis. These findings provide support for the practical implementation of rough box hives as a means to enhance propolis collection and colony health in multiple beekeeping contexts.

Therapeutic Potential of Malaysian Stingless Bee Propolis Extract Targeting Macrophages in Atherogenesis: A Review

Propolis is a sticky substance that originates from the collection of plant saps and resins by stingless bees. The bees blend this material with pollen and wax flakes, and their salivary fluids combine with the mixture to produce a potent compound that contains various chemical constituents, such as flavonoids and phenolic compounds. Numerous studies have revealed that propolis from stingless bees displays anti-inflammatory, antioxidant, immunomodulatory, and cardioprotective properties. Geniotrigona thoracica is one of the Malaysian stingless bee species, and propolis from this species is composed of a wide array of biochemical compounds and antioxidant properties that may have an anti-atherogenic effect. This review highlights the possible role of propolis from the Malaysian stingless bee G. thoracica as a macrophage-targeted therapeutic in atherogenesis, as macrophage-derived foam cell formation is integral to the development of atherosclerosis. The review first describes the characteristics, chemical content, and antioxidant properties of propolis from G. thoracica. It then discusses the pathogenesis of atherosclerosis, with a focus on macrophage-derived foam cell formation. Subsequently, the anti-atherosclerotic effects of propolis from G. thoracica are presented, and recent studies on the anti-atherosclerotic effects of propolis from honeybees worldwide are summarized for comparison. Finally, future perspectives are emphasized, highlighting the knowledge gaps that need to be investigated by researchers in this field.

Medicinal plant resin natural products: structural diversity and biological activities.

Covering: up to the mid of 2023Plants secrete defense resins rich in small-molecule natural products under abiotic and biotic stresses. This comprehensive review encompasses the literature published up to mid-2023 on medicinal plant resin natural products from six main contributor genera, featuring 275 citations that refer to 1115 structurally diverse compounds. The scope of this review extends to include essential information such as the racemic nature of metabolites found in different species of plant resins, source of resins, and revised structures. Additionally, we carefully analyze the reported biological activities of resins, organizing them based on the their structures. The findings offer important insights into the relationship between their structure and activity. Furthermore, this detailed examination can be valuable for researchers and scientists in the field of medicinal plant resin natural products and will promote continued exploration and progress in this area.

Chemical Constituents, Cytotoxicity, and Molecular Docking Studies of Tetragonula iridipennis Propolis

Objective: Propolis of Tetragonula iridipennis, which is one of the most popular stingless bees found in Vietnam, has been used to promote health and prevent disease. This study aims to identify the chemical constituents of T iridipennis propolis and their cytotoxic activity. Methods: The propolis sample was extracted with ethanol. The crude extract was isolated by combined chromatographic methods. The structures of isolated compounds were determined by electrospray ionization mass spectrometry and nuclear magnetic resonance spectra. The cytotoxicity was evaluated by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide method. The protein interactions of active compounds were explored by molecular docking study. Results: Sixteen known compounds, including 11 triterpenes, 3 xanthones, a sterol, and a flavonoid were isolated and identified. The propolis ethanol extract displayed good cytotoxicity against A-549 and KB cancer cell lines. 24 S,25-Dihydroxytirucall-7-en-3-one was the most active compound with IC50 values ranging from 18.75 ± 0.21 to 19.62 ± 0.36 µg/mL. Conclusions: Sixteen known constituents were identified from T. iridipennis propolis, of which 8 compounds were discovered for the first time. The propolis of T iridipennis has multiple sources of plant resin, among that Ailanthus triphysa (Simaroubaceae) was identified as a new plant source. A molecular docking study revealed that cytotoxic effects of 24 S,25-dihydroxytirucall-7-en-3-one, α-mangostin, 6-methoxy–bispyrano xanthone, and 3-isomangostin related to the inhibition of all 3 targets epidermal growth factor receptor, human epidermal growth factor receptor 2, and mammalian target of rapamycin (mTOR), while other isolated triterpenes exert their cytotoxicity by the inhibition of mTOR protein activity.

Purification of hydrogenated oil by microchannel separation coupling hydrocyclone

Hydrogenated oils are commonly used as solvents in the petroleum resin industry. The separation of particulate matter from hydrotreating oil is critical to product quality and the service life of the catalyst in the downstream fixed bed. Conventional separation methods, represented by diatomaceous earth filtration, suffer from low separation efficiency, high material consumption, generation of large amounts of hazardous waste, and cumbersome operation. Therefore, a physical method of microchannel separation coupling hydrocyclone was proposed. A 1 m3/h pilot pretreatment device was established to comprehensively evaluate the particle removal in hydrogenated oil. The high separation efficiency and long operation cycle were achieved by a microchannel separator with 0.5–1 mm particle size quartz sand. The single cycle of the microchannel separator was 75 h. The turbidity was decreased by about 64.3%, which was better than that of the traditional separation method (49.9%). The particle removal in hydrogenated oil by microchannel separator was about 75.0%, while the removal of diatomite separator in the same period was only 44.7%. In a 40 m3/h petroleum resin plant based on a microchannel separator, the operating cost and the hazardous waste emissions are reduced by 1,815,000 CNY/year and 208 tons/year, respectively. It is hoped that this study can not only promote the energy-saving and cleaner production of hydrogenated oil but also provide useful guidance for other petrochemical industries.