The article considers the evaluation of sustainability of natural complexes of low-mountain sections of the western slope of the Southern Urals (Minyarsk physical and geographical area) on the basis of analysis of landscape profiles on the indicator of sustainability of natural complexes. Peculiarities of the study area are highlighted: specific climatic conditions, complex geological and geomorphological conditions with ongoing industrial development, as well as a variety of soil and hydrological conditions combined with anthropogenic transformation of the territory. In the course of landscape profiling, as well as the application of methods of assessment of anthropogenic transformation of landscapes (at the level of the terrain), a decrease of diversity in natural complexes on the studied slopes was established, Replacement of typical plant communities by secondary successional communities in lowland areas dominated by horsetail. It has also been established that the aggregate of conditions in natural complexes indicates anthropogenic transformation of slope landscapes, the aggregate leading factor of which is the geochemical position on the element of the slope, Low resistance to external influence of the soil with a rinsing type of water regime defining plant associations. The obtained materials can be used as a basis for analysis of ecological condition of landscapes of the western slope of the Southern Urals, as well as characteristics of slope types of locations. Materials allow to further assess the recreational attractiveness of landscapes and the choice of ways of natural use of the studied area.