In this presented communication, a novel design of intelligent Bayesian regularization backpropagation networks (IBRBNs) based on stochastic numerical computing is presented. The dynamics of peristaltic motion of a third-grade fluid in a planar channel is examined by IBRBNs using multilayer structure modeling competency of neural networks trained with efficient optimization ability of Bayesian regularization method. The reference dataset used as inputs and targets parameters of IBRBN has been obtained via the state-of-the-art Adams numerical method. The data of solution dynamics is created for multiple scenarios of the peristaltic transport model by varying the volume flow rate, material parametric of a third-grade fluid model, wave amplitude, and inclination angles. The designed integrated IBRBNs are constructed by exploiting training, testing, and validation operations at each epoch via optimization of a figure of merit on mean square error sense. Exhaustive simulation of IBRBNs with comparison on mean square error, histograms, and regression index substantiated the precision, stability, and reliability to solve the peristaltic transport model.