Modern livestock development trends in the agricultural production structure include the use of feed mixers and distribution equipment. However, a stream of malfunctions and failures is reported for mixer-feeders due to factors that are specific to agricultural enterprises in Ukraine, which reduce the operational reliability of feed mixers and distributors. The study aims to evaluate the quantitative indicators of the in-service reliability of mixer-feeders and develop methods to improve them. The reliability test plan [NMT] was used, which implies a certain number of research objects (N), objects undergoing repair in case of performance loss (M), and tests terminated when the operating time (T) is reached. Initial information was collected and processed, and empirical data on the time between failures of KUHN PROFILE 12.2 DS and PROFILE 14.2 DS mixer-feeders in Ukraine were analysed. The analysis established that the faulty condition of mixers-feeders in the initial operation period is caused by the second complexity group failures. Failures related to the loss of the grinding and mixing mechanism, which limits the average time between failures of the feed mixture and distribution equipment, were identified among the second complexity malfunction group. A statistical analysis of the mixer-feeder failure occurrence was carried out. The failure probability of the grinding-mixing mechanism of the feed mixer was determined to be within the normal distribution law. The main parameters of the given theoretical distribution law were determined by calculation results. The calculations determined that the average time between failures is 3152.0 motor-hours; the standard deviation is 902.6 motor-hours; and the coefficient of variation is 0.40. An average time between failures of the study objects was proved to be consistent with the normal distribution law following Kolmogorov’s agreement criterion. Calculations determined that the average reliability index value, according to the normal distribution law, is within the confidence intervals: 1964.2 motor-hours – lower confidence limit; 4339.8 motor-hours – upper confidence limit. The obtained results may be used to improve the mixer-feeder operational reliability