Topological insulators (TIs), exhibiting topologically protected edge and interface waves, have recently emerged in phononic systems. Reconfigurabilty is essential for enabling TI-based applications. One potential means for achieving reconfigurability employs shunted piezoelectric (PZT) disks in which a unit cell’s mechanical impedance is altered using negative capacitance circuits. Dynamic reconfigurability and programmability of such material platforms can then be obtained through simple on/off switching. In this vein, we propose and experimentally verify an electroacoustic TI which exhibits programmable topologically protected edge states useful for acoustic multiplexers, demultiplexers, and transistors. This reconfigurable structure is composed of an elastic hexagonal lattice whose unit cell contains two shunted PZT disks, each connected to a negative capacitance circuit by an on/off switch. Closing one or the other circuit results in the breaking of mirror symmetry and yields mechanical behavior analogous to the quantum valley Hall effect. By interfacing two topologically distinct materials, a domain wall is introduced exhibiting a localized interface state topologically protected from backscattering at defects and sharp edges. Through the use of programmable time-division, in which domain walls appear and disappear in time, we demonstrate multiplexing and demultiplexing. We also demonstrate an acoustic transistor using the same programmable platform, before closing with a discussion on future research directions.