In order to develop the corrosion protection technology for the target reservoir, temperature-resistance self-healing coating has been constructed. The corresponding corrosion resistance property is investigated by comparing with the commercial phenolic epoxy coating and commercial heavy-duty coating. Electrochemical tests, SEM/EDS, micro-Raman spectrometer, and FTIR are applied to characterize the coatings after exposed to the simulated wellhead and well bottom condition. The results show that no degradation, peeling off and bubbling can be observed on the temperature-resistance self-healing coating under both conditions. The coating plays a fine healing role that there are no obvious corrosion products identified around the artificial scratch. The corrosion resistance of the temperature-resistance self-healing coating at the characteristic frequency of 0.01 Hz is about triple that of the other two coatings. The corresponding corrosion current density is about 7 times lower than that of the heavy-duty coating. There is no S or Cl corrosive element identified at the interface of coating and the substrate, so the coating shows great resistance to the corrosive ion penetration.