Abstract: The integration of chemical admixtures and alternative materials in concrete production has become a focal point in advancing construction technologies. This study investigates the combined effects of superplasticizers and mill scale on the workability and compressive strength of M30 grade concrete. Three different superplasticizers—Auramix 200, SikaPlast®-3069 NS, and Master Polyheed 8126—are evaluated for their performance enhancements in concrete. Additionally, mill scale, an industrial by-product, is utilized to partially replace sand in varying proportions (0%, 20%, 40%, 60%, 80%, and 100%) to assess its viability as a sustainable aggregate alternative. The experimental phase is divided into three stages: initially assessing the workability and compressive strength of M30 concrete without admixtures; subsequently incorporating mill scale to observe its effect on concrete properties; and finally combining mill scale with each superplasticizer to maintain workability while evaluating the compressive strength. Slump cone tests are conducted to measure workability, and compressive strength tests are performed at 7, 14, and 28 days. Results indicate that the inclusion of superplasticizers significantly enhances workability, with Auramix 200 showing the highest improvement. The addition of mill scales up to 60% replacement level increases compressive strength, with a notable peak at 60% replacement for both plain and superplasticizer mixes. However, higher replacement levels (80% and 100%) result in reduced strength and workability. Among the superplasticizers, Auramix 200 exhibits the best overall performance in conjunction with mill scale. This study concludes that the strategic use of superplasticizers and mill scale can produce high-performance, sustainable concrete. Future research should explore long-term durability aspects and optimize mix designs for broader applications in construction.