Knowledge Of Pharmacovigilance Research Articles

Impact of Educational Intervention on Knowledge, Attitude & Practice About Pharmacovigilance in Nursing Students in A Tertiary Care Teaching Hospital in India: A Cross-Sectional Study

Background: It is crucial for healthcare professionals to know how to report adverse drug reactions (ADRs). To improve reporting rates, it is essential to improve knowledge, attitude and practice (KAP) of healthcare professionals regarding Pharmacovigilance (PV) and adverse drug reactions (ADR) reporting. According to previous studies, there has been a lack of knowledge in nursing students regarding Pharmacovigilance (PV) and reporting of adverse drug reactions (ADR). Hence, this study was planned to assess the impact of educational intervention on nursing students' knowledge, attitude, and practice of pharmacovigilance at a tertiary care teaching hospital in India. Materials and Methods: This was an interventional study conducted among 93 BSc nursing students at a tertiary care teaching hospital, India. Each participant was explained the purpose of study and asked to fill in a questionnaire about their knowledge, attitude and practice of pharmacovigilance. The post-KAP questionnaire was re-circulated among participants at the end of the intervention and data was analyzed using Chi square test. Results: The study involved 93 BSc nursing students aged 21.52 ± 1.11 years, with a male to female ratio of 1:2. All statistical calculations were performed using Graph Pad prism v10.1.0. Results showed significant differences in understanding pharmacovigilance between pre-intervention and post-intervention, and a significant change in attitudes towards pharmacovigilance due to the educational intervention. A statistically greater proportion of students learned about Pharmacovigilance and ADR reporting forms. Conclusion: The Continuing Medical Education (CME) and group discussions significantly enhanced the knowledge and attitude of nursing students regarding pharmacovigilance.

Cross-sectional study of pharmacovigilance knowledge, attitudes, and practices based on structural equation modeling and network analysis: a case study of healthcare personnel and the public in Yunnan Province.

This study focuses on understanding pharmacovigilance knowledge, attitudes, and practices (KAP) in Yunnan Province, employing Structural Equation Modeling (SEM) and network analysis. It aims to evaluate the interplay of these factors among healthcare personnel and the public, assessing the impact of demographic characteristics to inform policy and educational initiatives. A cross-sectional survey was conducted in Yunnan, targeting healthcare personnel and the public. Data collection was through questionnaires, with subsequent analysis involving correlation matrices, network visualization, and SEM. The data analysis utilized SPSS 27.0, AMOS 26.0, and Gephi software for network analysis. This study evaluated pharmacovigilance KAP among 209 public participants and 823 healthcare personnel, uncovering significant differences. Public respondents scored averages of 4.62 ± 2.70 in knowledge, 31.99 ± 4.72 in attitudes, and 12.07 ± 4.96 in practices, while healthcare personnel scored 4.38 ± 3.06, 27.95 ± 3.34, and 7.75 ± 2.77, respectively. Statistically significant correlations across KAP elements were observed in both groups, highlighting the interconnectedness of these factors. Demographic influences were more pronounced among healthcare personnel, emphasizing the role of professional background in pharmacovigilance competency. Network analysis identified knowledge as a key influencer within the pharmacovigilance KAP network, suggesting targeted education as a vital strategy for enhancing pharmacovigilance engagement. The research reveals a less-than-ideal state of pharmacovigilance KAP among both healthcare personnel and the public in Yunnan, with significant differences between the two groups. SEM and network analysis confirmed a strong positive link among KAP components, moderated by demographics like age, occupation, and education level. These insights emphasize the need to enhance pharmacovigilance education and awareness, thereby promoting safer drug use.

IMPACT OF AN EDUCATIONAL INTERVENTION ON AWARENESS OF PHARMACOVIGILANCE AND ADR REPORTING AMONGST AYURVEDIC POST-GRADUATE STUDENTS

Objective: Adverse drug reactions (ADR) are one of the major causes of morbidity and mortality. Ayurveda is one of the oldest healthcare systems, widely practiced in India and there is a misconception that AYU and H drugs are free from ADRs. Post-graduate (PG) students are fresh pass-out medical graduates and are major contributors in providing health care at tertiary care centres. The present study was planned with the aim of evaluation of knowledge, attitude and practice of pharmacovigilance amongst PG students and impact of an educational intervention on their knowledge and attitude.
 Methods: A pre-test, post-test questionnaire based cross-sectional study was conducted. 41 postgraduate students from different branches were included. An educational intervention in the form of sensitization programme, including basic knowledge of pharmacovigilance, monitoring system for pharmacovigilance andcase-based ADR reporting was conducted. A validated questionnaire consisting of questions regarding knowledge, attitude and practice of pharmacovigilance was provided as a pre-test and post-test and the results were statistically evaluated.
 Results: Scores of pre-test reveals that the participants were aware of basic knowledge of pharmacovigilance but knowledge about reporting procedure and the monitoring system was lacking. The difference in mean scores of pre and post-test was statistically significant. Most of the participants agreed that reporting ADR improves drug safety and frequent sensitization programmes should be conducted but practically, they had not undergone any training/sensitization programme.
 Conclusion: The study reveals that even with the favorable attitude towards drug safety and ADR reporting, the unawareness of PG students about the monitoring system and deficient ADR reporting indicatesa strong need for the conduction of repeated training/sensitization programmes and other suitable methods for encouraging ADR reporting.

Knowledge, attitude and practice of pharmacovigilance among medical students

Background: Spontaneous voluntary adverse drug reaction (ADR) reporting is the backbone for the successful functioning of the Pharmacovigilance Programme of India. The aim of pharmacovigilance is to ensure safe and rational use of medicines, once they are released for general use in the society. Targeting the younger doctor for sensitization toward pharmacovigilance is the key to ensure practice of adverse drug reactions (ADR) reporting in clinical practice. The objectives of this study are to evaluate the knowledge, attitude, and practice (KAP) of pharmacovigilance among medical students at LLRM Medical College, Meerut, a tertiary care teaching hospital. Methods: A cross-sectional study was carried out using a pretested questionnaire. The questionnaire was designed to assess the KAP regarding pharmacovigilance. The medical students (2nd year, final year, and interns) were included in the study. Only the participants who gave their consent were included in the study. Results were calculated by proper statistical analysis. Results: The current study was conducted in a LLRM Medical College, Meerut, which included a total of 250 medical students of which 40% 2nd year, 40% final year students, and 20% interns. Most of them (83%) accepted that reporting ADR is necessary, and pharmacovigilance should be taught in detail to health-care professionals. Conclusions: This study demonstrated that knowledge of pharmacovigilance among medical students is improving gradually and pharmacovigilance and ADR reporting needs to be made compulsory, have better, interesting ways to learn and understand it, so that the students can practice it with confidence in their clinical practice.

Assessment of Knowledge, Attitude, and Practice of Pharmacovigilance and Materiovigilance among Oral Health Practitioners in India

ABSTRACT Aim: This electronic survey was carried out to assess the knowledge, attitude, and practices among the oral health practitioners. Methods: A questionnaire survey was conducted among undergraduates, graduated practitioners, and specialist practitioners. A Google Form that included a specified instruction format, informed consent with a clear description of the purpose of the study, and questions in different categories were sent through Whatsapp and email. Descriptive statistics were used to analyze responses. The association of knowledge and attitude with respect to oral health professionals was analyzed with the Chi-square test. Results: The questionnaire was completed by 570 participants. Thirty percent of participants encountered ADR related to the drugs available in the market and 33.2% of participants encountered adverse reaction related to materials used in practice. ADR should be reported as soon as it is detected, according to this study about 12.1% of participants reported the ADRs, and this reporting is primarily for patient safety. Almost 66.8% of participants perceived that dental products can cause ADR owing to a lack of information about ADR and reporting procedures, or due to fear of legal concerns. Only about 9.5% of the participants had previously attended an ADR workshop. Conclusion: Oral health practitioners have a general understanding of ADR; however, there is substantial evidence of underreporting and a lack of reporting system information. Organizing an orientation program and raising awareness about ADR reporting could help improve spontaneous reporting and better patient care.

A study on knowledge, attitude, and practice of pharmacovigilance and adverse drug reactions awareness among health-care students in a tertiary care teaching hospital, Telangana, India

Background: The training of health-care students in pharmacovigilance (PV) fulfills curriculum requirements as well as providing early exposure for a secured use of medications in the future. Active participation of health-care professionals ensures successful implementation of PV. Aims and Objectives: To assess the knowledge, attitude, and practice of PV among health-care students. Materials and Methods: A cross-sectional, questionnaire-based study was conducted at Mamata Academy of Medical Sciences, Bachupally, between May 1st, 2023, and October 31st, 2023. After obtaining permission from the Institutional Ethics Committee, all health care students were provided with a study questionnaire in Google Docs. Results: Medical undergraduates (57.45%) were a majority of the 369 respondents (79.35%) enrolled. PharmDs had the highest response rate (84.76%), followed by medical (78.52%), and nursing (75.56%). The knowledge of PV terminologies was good among 50.47% of medical students, whereas 48.31% pharm ds were aware of adverse drug reactions (ADR) reporting systems and concerned regulatory authorities. 66.51% of medical students and 57.3% of Pharmds had a positive attitude toward PV. However, most of the nursing students had poor knowledge and expressed a negative attitude. Around 33% of the study participants had encountered ADRs, and 33% of the encountered ADRs were reported. Medical undergraduates had significantly better knowledge and attitude, with a mean (standard deviation) total score of 8.03 (2.08) and 3.78 (0.84), respectively (P < 0.01). Conclusion: The disparity of knowledge and attitude from the practice of PV among medical students and PharmDs consequently emphasizes to enroute our strategic initiatives to address the practical difficulties and foster a better reporting culture in the future.

Knowledge, attitude, and practice of pharmacovigilance among undergraduate medical students in a tertiary care teaching hospital of Northern Maharashtra

Background: Adverse drug reactions (ADRs) contribute significantly among underlying reasons of morbidity and mortality in the health-care system. ADR reporting is the core of pharmacovigilance program but still insufficient reporting by health professionals exists in various part of our country. Aims and Objectives: The study was designed to evaluate the knowledge, attitude, and practice (KAP) of undergraduate medical students about ADR and pharmacovigilance. Materials and Methods: It was a cross-sectional study. Questionnaire was comprising 21 questions to evaluate the KAP of pharmacovigilance among undergraduate medical students. Descriptive statistics were analyzed and analysis of variance test was applied for statistical difference between the groups. Results: One hundred and eighty-six students participated in the study. The average score of 2nd year, 3rd year, and 4th year for knowledge was (4.50, 5.15, and 4.59) and for attitude was (5.37, 5.70, and 5.59) and for practice was (1.14, 1.78, and 1.36). There is a significant difference in average score between groups for knowledge and attitude, but not for practice. They have higher attitude and knowledge, but poor practice regarding pharmacovigilance. Conclusion: Respondent of the study was not completely aware of pharmacovigilance and ADR reporting. There is an increased need to create awareness and to train students about pharmacovigilance.

A cross-sectional study on knowledge, attitude, and practice of health-care professionals about adverse drug reactions reporting in a tertiary care teaching hospital of southern Rajasthan

Background: Adverse drug reaction (ADR) reporting is the integrity of healthcare professionals (HCPs) to counteract fatal outcomes aroused by the use of medications during therapy. The underreporting of ADRs imposes major problems globally. The pharmacovigilance program plays a key role in detecting and preventing ADRs. Targeting the upcoming younger generation of HCPs and sensitizing them towards ADR reporting in their clinical practice is essential. Aims and Objectives: The main objective of our study is to measure the knowledge, attitude, and practice of interns and postgraduates at our institute towards ADR reporting and pharmacovigilance. Materials and Methods: This study was a cross-sectional study conducted on interns and postgraduates of a tertiary care teaching hospital in Udaipur, Rajasthan. A set of 28 standard questions related to knowledge, attitude, and practice of pharmacovigilance and ADR reporting were distributed among 106 students after taking the ethical approval from the institute. The collected data were analyzed using SPSS (version 20) software in percentage. The Chi-square test (χ2) was used, and P < 0.01* was considered significant statistically. Results: In our study, we found most of the participants were in 21–30 age groups (84.19%); male participants were (67%) in comparison with females (33%). The majority of interns showed their interest in participation (66%) rather than postgraduates (34%) in this study. The overall knowledge (14.645, P = 0.01), attitude (14.64, P = 0.01), and practice (35.712, P = 0.01) of HCPs were found to be significant. Conclusion: We conclude from this study that both interns and postgraduates have good knowledge of ADR reporting, but interns lack practice in their daily duties due to fear of heavy paper work, and postgraduates lack attitude towards ADR reporting due to heavy duty schedules. Most of the participants, i.e., interns and postgraduates, felt ADR reporting was their primary responsibility along with patient safety. Recurrent training and sensitization of upcoming medical professionals about ADR reporting will impart better patient compliance and eradicate fatal outcomes. They also suggest a separate working body needs to keep by institutions to collect the ADR reports during their busy duty schedules.

Evaluation of Knowledge, Attitudes, and Perceptions of Pharmacovigilance (PV) amongst Health Professionals and Students

Pharmacovigilance (PV) and drug safety remain important areas of study worldwide. Unfortunately, medical professionals and students generally do not understand the reporting of PVs and adverse drug reactions (ADRs). This study compares student knowledge, attitudes, and perspectives with those of healthcare professionals in the pharmacy, medical, dental, and nursing fields. A questionnaire study was conducted to determine the level of understanding and attitudes toward PV and ADR reporting among 82 healthcare professionals (52 pharmacists, 15 physicians, 10 dentists, and 5 nurses) and 100 undergraduate healthcare students (45 pharmacies, 12 physicians, 35 dentists, and 8 nurses). According to the survey, among medical professionals and students, pharmacists are better educated about pharmacovigilance and adverse drug reactions than physicians, dentists, and nurses. The study found that pharmacists had a more favorable attitude toward pharmacovigilance and ADR reporting than other healthcare professionals. Doctors and medical students ranked second in terms of understanding of pharmacovigilance and the ADR reporting system, followed by dentists and dental students, and nurses and nursing students ranked last. In conclusion, pharmacists and pharmacy students exhibited superior knowledge, attitudes, and views of PV and ADR reporting compared to other healthcare professionals and students. The paper underlines the necessity of integrating pharmacovigilance education into the Libyan healthcare system and school curricula to train staff and educate students for real-world practices and workplaces.

Assessment of knowledge, attitude and practice of pharmacovigilance and ADR reporting in health care professionals

Background: Lack of awareness among healthcare professionals is cited as one of the main reasons along with under reporting of adverse drug reactions. Knowledge, attitude, and practice (KAP) studies can help to understand various issues and improve pharmacovigilance system.
 Objectives: The present study was undertaken to assess the knowledge, attitude, and practices (KAP) regarding pharmacovigilance and ADR reporting among healthcare professionals at the various departments of hospitals in Northern Kerala to get an insight into the causes of under-reporting of ADRs.
 Materials and Methods: The data was collected using a pre-designed questionnaire. A total of 25multiple choice questions related to knowledge, attitude and practice. There were 6 Knowledge based 7 Attitude and 12 Practice based questions. The participants were graded in three categories as good, fair and poor depending on the mean score. The data were interpreted by calculating the frequencies, one-way ANOVA test.
 Results: A total of 300 healthcare professionals who completed the questionnaire were considered of which 110 were doctors, 98 were nurses and 92were pharmacist. Among them, doctors have relatively better score than nurses and pharmacists in knowledge and attitude. Most healthcare professionals have showed fair practice in pharmacovigilance and ADR reporting and the pharmacists being the best performers.
 Conclusion: To facilitate the culture of reporting and creating awareness among health professionals, CME, workshops, conferences, post training reminders such as periodic E-mails and SMS alerts should be conducted. Pharmacovigilance is being taught to some degree in theory, but the knowledge on the practical method is lacking. The existing academic curriculum can be amended to incorporate the application of pharmacovigilance in the medical practice.

Knowledge, Attitude and Perception of Pharmacovigilance Science in Ayurveda among Ayurved pharmacy undergraduates - A Cross Sectional Study

Background: India is known for its traditional medicinal systems. Ayurveda, Siddha and Unani systems are being practised since ages and their use have accepted in other countries in era of globalisation. There is a wide spread misconception that all drugs of “natural” origin are “safe”. Many drugs not only of allopathy but homeopathy as well Ayurved, having undesirable unwanted effects beyond therapeutic action called Adverse Drug Reaction (ADR). Ministry of AYUSH, Government of India, New Delhi has initiated the Pharmacovigilance Program for Ayurved, Siddha, Unani & Homeopathy drugs (ASU & H drugs). Aim and Objectives: To evaluate knowledge, attitude and perception of Pharmacovigilance among Ayurved pharmacy undergraduates. Materials and Methods: It was a prospective, cross-sectional study conducted among Ayurved pharmacy undergraduates perusing their study at government Ayurved College during 2022. The questionnaire was designed to test knowledge, attitude and perception of Pharmacovigilance. Basic and study data was entered in Microsoft Office Excel 2016 and descriptive statistics was used. Result: Majority students had knowledge about “ADR’ and “Pharmacovigilance” and “ADR” reporting Centre” but where and to whom and how to report was lacking as there have not been exposed to any practical training and awareness session. Majority participants were agreed that all the drugs including ASU & H has adverse drug reaction and need to report and should be mandatory. Conclusion: There is a need of more awareness and practical/ hand to hand training programme related to Pharmacovigilance and ADR reporting to Undergraduate Ayurved Pharmacy Students to sensitise them and to strengthen the reporting culture for ASU & H drugs form early stage.

Knowledge and perception of pharmacovigilance among pharmacy students and pharmacy professional students

Background: Adverse Drug Reaction (ADR) contributes to high morbidity and mortality rate worldwide. This can be minimised through pharmacovigilance. It is important to evaluate the level of knowledge and perception of pharmacovigilance among pharmacy students. Objective: To describe the level of knowledge and perceptions of final-year pharmacy students and students of pharmacy professional programs in Yogyakarta regarding pharmacovigilance. Method: A cross-sectional study involved 437 pharmacy students from five different universities in Yogyakarta, who were selected using a convenience sampling technique. Data were analysed to describe the characteristics of the respondents and their level of knowledge and perceptions about pharmacovigilance. Result: The majority of final year students in pharmacy and pharmacy professional programs had acquired a high level of knowledge about pharmacovigilance with a percentage of 54.0%. They also shared a positive perception of the implementation of pharmacovigilance with a percentage of 55.6%. Conclusion: Final-year pharmacy students and students of the pharmacy professional program have good knowledge and perceptions towards pharmacovigilance.

Assessment of educational intervention impact on improving pharmacovigilance knowledge among health care providers: A study from different hospitals in tanzania

Assessment of educational intervention impact on improving pharmacovigilance knowledge among health care providers: A study from different hospitals in tanzania

Safeguarding human rights to health: a systematic review of supply chain impediments to safe medicines in developing nations

Purpose A key feature of human rights in health is access to safe, effective and affordable medicines. Pharmacovigilance is advocated for monitoring intended/unintended effects of medicines to assure their safety. The purpose of this paper is to synthesize knowledge about supply chain impediments to safe medicines in developing nations and contribute to future development of research in this field. Design/methodology/approach This paper conducts a structured literature review based on Preferred Reporting Items for the Systematic Reviews and Meta-Analyses guidelines. It aims at profiling supply chain impediments to safe medicines in developing nations by reviewing 46 recent pharmacovigilance-specific papers published between 2005 and 2020. Findings Analysis of reviewed articles identified criticality of supply chain impediments that affect constituents across pharmaceutical in developing nations, which still struggle to maintain robust national pharmacovigilance systems due to lack of awareness, policy and practices. Research limitations/implications Research results can be applied by pharmaceutical industry decision-makers and drug safety professionals in developing nations. Because the review is qualitative in nature, its implication ought to be tested after actual implementation. Practical implications This review can help identify underinvestigated impediments and methods to aid in developing new pharmacovigilance knowledge areas in developing nation context. Social implications The review uncovers gaps in global health equity dialogue in developing nations. It also recognizes that macrolevel supply chain impediments exist due to unfair disease burden and health inequities in developing nations. Originality/value The paper examines supply chain impediments to safe medicines in developing nations with insights for future pharmacovigilance research. Identifying and classifying supply chain impediments through this review is the first step toward creating effective interventions for these impediments to safe medicines.

Influence of Educational Intervention on Awareness and Attitude of Nursing Students Towards Adverse Drug Reaction Reporting During Coronavirus Disease 2019 (COVID-19) Pandemic: A Quasi-Experimental Study.

Under-reporting of adverse drug reactions (ADRs) is a major concern of the pharmacovigilance program of India and has deteriorated further with the Coronavirus Disease 2019 (COVID-19) pandemic. Imparting the knowledge of pharmacovigilance among nursing students would significantly enhance patient care. Hence, this study was framed to evaluate the effect of an educational intervention on awareness and attitude of ADR reporting among nursing students during the COVID-19 pandemic. A quasi-experimental pretest-post-test study was conducted among nursing students of a tertiary care hospital in South India. The students were asked to fill out a validated questionnaire to assess Knowledge, Attitude, and Practice on ADR reporting, before and after the educational intervention. Knowledge and attitude results were analysed using Mc Nemar's test. A total of 135 nursing students attended the educational intervention and completed pretest and post-test questionnaires. Around 130 (96.3%) and 107 (79.3%) students were aware of pharmacovigilance and ADR monitoring center following the intervention. Median (interquartile range) of knowledge scores before and after the intervention were 3 (2-3) and 5 (3-7), respectively. Overall knowledge score of ADR reporting significantly improved after the intervention. Sixty two (45.9%) students agreed that ADR reporting would enhance patient safety. ADR reporting was practised by 52 (38.5%) participants. Nearly, 107 (79.3%) students were interested to participate in similar pharmacovigilance training programs. Educational intervention in pharmacovigilance improved the cognitive and affective domains of pharmacovigilance in nursing students. Periodic training programs are essential for sustained behavioural change in students.

Revealing Insights: Investigating Pharmacovigilance Knowledge, Attitudes, and Practices at a Leading Tertiary Care Hospital in Faisalabad

Background: The aim of present cross-sectional survey is to investigate healthcare workers' knowledge, attitude, and behaviour regarding pharmacovigilance at tertiary care hospital, Faisalabad. Methods: The present cross-sectional survey was conducted in tertiary care hospital, Faisalabad. The study populations of Eighty (80) male and female health care workers were included in this study. Demographic data and information about workers' knowledge, attitude, and behaviour regarding pharmacovigilance was collected on an interview schedule administered through custom designed structured Performa. The data regarding healthcare workers' knowledge, attitude, and behavior concerning pharmacovigilance at a tertiary care hospital were analyzed using SPSS. Results: The findings of study depicted a positive relationship between knowledge, attitudes, and practices among healthcare workers. Pharmacovigilance is a critical component of drug safety and plays a crucial role in identifying and managing adverse drug reactions and other drug-related problems. Conclusion: Adequate knowledge, skills, and attitudes towards pharmacovigilance among healthcare workers are essential to ensure the safety of medications and promote better patient outcomes. Study can provide valuable insights into the current state of pharmacovigilance in the region and identify areas for improvement. The also enhancing education and training programs for healthcare workers in pharmacovigilance, fostering a reporting culture for adverse drug reactions and adverse events, and establishing robust pharmacovigilance systems and processes are crucial elements for safeguarding medication safety and efficacy, as well as enhancing patient care. Keywords: Healthcare Workers, Pharmacovigilance, Knowledge, Attitude, Behavior, Cross-Sectional Survey, Tertiary Care Hospital, Faisalabad

EVALUATION OF THE FEEDBACK ON PHARMACOVIGILANCE BASIC AWARENESS PROGRAM AMONGST THE MEDICAL POST GRADUATE RESIDENTS OF A RURAL TEACHING HOSPITAL

Introduction:The World Health Organization (WHO) defines an Adverse drug reaction (ADR) as a response to a drug which is noxious, unintended, and which occurs at doses normally used in man for the prophylaxis, diagnosis, or therapy of disease, or for the modification of physiological function. Adverse drug reactions (ADRs) are a major clinical problem and are main cause of death and serious disease in patients and a key cause of drug attrition in the pharmaceutical industry, as nearly more than 90% of drug molecules do not succeed in preclinical/clinical studies due to a deficiency of safety and efficacy. The chief reasons for withdrawal of already approved drugs are cardiovascular and hepatic adverse effects. The main goal was, our future healthcare providers should have basic pharmacovigilance knowledge, how to detect and prevent ADRs in order to rationally reporting ADRs and preventing serious health problems. The main aim was to sensitize all the health care providers regarding Pharmacovigilance activities. Materials & Method:The present retrospective and observational study was initiated by collecting necessary information about the Pharmacovigilance awareness program conducted during July 2017. The participants (n=47) were second year MD/MS/Diploma post graduate students (Medical), residents of Dhiraj Hospital attached to Smt. B. K. Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth an Institution deemed to be University, Piparia. Results & Discussion:The participants (n=47) rated the quality of presentations and content from excellent to good for both the sessions. With regard to the usefulness of the sessions, it was also rated from excellent to very good. They felt both the sessions were interactive, interesting & useful in all aspects. The quality of presentation was rated as good to excellent. All 47 (100 %) participants reported that it was an excellent workshop with good interactive session and interesting group activity. Majority of participants, 23 (48.93%) found that the workshop would help them to value add in their patient care in future, which implied that workshop was beneficial to convey the importance of national programme to the participants. Forty six (97.87%) participants said that they will like to attend this type of workshop in future also. The resource persons through interactive sessions, had given an overview on Pharmacovigilance, which was followed by hands on technique, how to fill ADR forms and group discussions, at the end of each workshop feedback forms were distributed to all participants. Pharmacovigilance workshops were conducted to generate awareness regarding ADR reporting amongst doctors is essential to promote the rational and safe use of medicines. Conclusion:Feedback from the post graduate healthcare professionals plays a key role in the reassurance and augmentation of the quality and their understanding on their role in pharmacovigilance and hands on training in ADR form filling group activity. Further, the study implies that workshop was beneficial to convey the importance of national programme to the participants.

Pharmacovigilance and Adverse Drug Reaction Reporting among the General Public in Lithuania: A Cross-Sectional Study.

Background: Despite the fact that for over ten years, Lithuanian consumers have been able to report adverse drug reactions (ADR) directly to the competent authority, reporting rates remain low. A comprehensive understanding of consumer perceptions and experiences regarding ADRs is needed to ascertain further factors impacting their engagement in ADR reporting. This study aimed to assess consumer knowledge of, attitude toward, and practice of reporting ADRs. Methods: A questionnaire-guided cross-sectional survey among 404 consumers between October 2021 and June 2022 was conducted. The semi-structured questionnaire comprised open-ended and closed-ended questions to explore the sociodemographic characteristics and general knowledge of ADRs and pharmacovigilance. Other question items evaluated attitudes toward ADR reporting and ADR reporting practice. The data were summarised using descriptive statistics, while the chi-square test was used to assess categorical variables at p < 0.05. The overall percent score in the knowledge and attitude domains was divided into groups of "poor", "moderate", and "good" knowledge, as well as "positive" and "negative" attitudes. Results: While having a generally poor understanding, this study demonstrates that Lithuanian consumers have a favourable attitude toward pharmacovigilance, particularly regarding issues involving the requirement for reporting. The data also revealed the justifications for reporting and not reporting ADRs. Conclusions: The current study provided the first understanding of consumer awareness and ADR reporting intentions, which can help to develop educational campaigns and interventions addressing pharmacovigilance and ADR reporting.

Knowledge of pharmacovigilance among healthcare professionals and the impact of an educational intervention

Aim. To determine the knowledge regarding various aspects of pharmacovigilance among doctors and nurses of a tertiary care teaching hospital and to evaluate the effect of an educational intervention. &#x0D; Methods. A cross-sectional study was conducted among doctors and nurses of a tertiary care teaching hospital. The participants attended a one-hour educational session during which the concept of pharmacovigilance, the Pharmacovigilance Program of India, the need for reporting ADRs, and the method of reporting were explained by a subject expert. A 20-item questionnaire was used to assess their knowledge regarding pharmacovigilance before and after an educational session. The pre-post comparisons were done using Wilcoxon’s signed-rank test. A p-value less than 0.05 was considered statistically significant. &#x0D; Results. Forty-two doctors and 115 nurses participated in the study. A significant improvement in the participant scores was seen following the educational intervention in both doctors (Z = −5.344, p &lt; 0.001) and nurses (Z = −8.808, p &lt; 0.001). Lack of knowledge/awareness was perceived as the major barrier for ADR reporting among nurses as well as doctors. &#x0D; Conclusion. There is need for education and training among doctors and nurses to enhance their knowledge about drug safety and reporting practices. Educational intervention is likely to improve the knowledge regarding pharmacovigilance, and thereby enhance reporting by healthcare professionals.

Knowledge, Attitudes and Practices of Dentists Regarding Pharmacovigilance and Reporting of Adverse Drug Reactions in Northwestern Turkiye: A Cross-Sectional Study

ABSTRACT Objectives: The drugs commonly used/prescribed by dentists/physicians or consumed by patients may cause adverse drug reactions (ADRs). Therefore, the possibility of dentists to encounter an ADR during their professional lives cannot be underestimated and the contribution of dentists to pharmacovigilance systems by notifying spontaneous ADR reports play an important role in the early detection and prevention of ADRs. This study aimed to assess the knowledge, attitudes and practices of dentists regarding pharmacovigilance and ADR reporting. Materials and Methods: A questionnaire with 30 questions evaluating knowledge, attitudes and practices of pharmacovigilance and ADR reporting among general dentists (GDs) and specialist dentists (SDs) was distributed electronically in northwestern region of Turkey. Data were statistically analyzed (p &amp;lt; 0.05). Results: Most of the participants were able to define the terms of pharmacovigilance (64.7%), ADR (74.9%) and side-effect (58.1%). SDs were significantly more aware of ADRs related to the drugs used/prescribed by dentists/physicians and other drugs consumed by patients than GDs. Additionally, awareness of ADRs regarding these drugs was significantly higher among participants with ≤12 years of experience (p&amp;lt;0.05). Only 2.8% of participants (4 GDs, 6 SDs) reported an ADR in their professional lives. However, 52.5% of participants had encountered an oral mucosal ADR during their professional lives, which was statistically higher in the group of SDs and participants with &amp;gt;12 years of experience (p&amp;lt;0.05). Conclusions: The role of dentists in the diagnosis and reporting of ADRs should not be underestimated since they are an integral part of the healthcare system. The contribution of both GDs and SDs to the ADR reporting system needs to be improved in Turkey. Additionally, ADR reporting should be integrated into daily practices of dentists.