Personal Access Research Articles

SOME PROBLEMS OF PROTECTION OF COMMERCIAL SECRETS

The purpose of this article is to clarify some of the problems of trade secret protection and suggest ways to overcome them. The methodological basis of the study are general and special methods of cognition. The use of these methods made it possible to describe the problems of trade secret protection. Results: the study found that breaches of trade secrets are considered by international law as unfair competition. At the same time, the laws on unfair competition in the countries of the continental (pandectic) legal system are based on the theory of confidentiality (de facto monopoly). Therefore, the foreign experience of the countries of the continental (pandect) system of law is of particular importance for the formation of Ukrainian legislation on trade secrets. Discussion: given the specifics of the studied object of intellectual property rights and based on the analysis of international experience found that national approaches to ways to protect intellectual property rights to trade secrets are not effective because they do not provide and do not provide maximum material satisfaction for the person access to which is violated, and quite severe consequences for the offender. It is proposed to improve the current legislation of Ukraine on the protection of trade secrets.

Technology Has Empowered the Consumer, but Marketing Communications Need to Catch-Up: An Approach to Fast-Forward the Future

No industry is immune to digital transformation. Social media is empowering individuals everywhere and driving a democratization of personal access that is fundamentally different from the top-down communications associated with traditional mass-media at the outset of globalization. Social media, social sharing, and social business have been accelerated by COVID-19. The rise of e-commerce has materially affected not only how people buy, but also how people research their purchase decisions. Marketing has not kept up with this paradigm shift, and by simply viewing digital as another media channel misses the shift in consumer power and the imperative to engage rather than advertise. Narratives are part of our everyday, and popular stories affect individual and community behaviour. We demonstrate how big data and AI can track the narratives that are shaping our world. Engaging with these narratives can improve marketing decision-making by addressing what people feel is important and result in better outcomes to grow and sustain brand equity in our contemporary, digital world.

Life Skills Education Through Non-Formal Education For People With Physical Disabilities

This study aims to identify and identify life skills education through non-formal education for persons with physical disabilities. Individuals who have physical limitations are called persons with physical disabilities. In the social environment, society tends to give negative stigma to people with physical disabilities and other problems that are in the spotlight are the low participation and provision of job opportunities for people with disabilities in obtaining work. This study used qualitative research methods. This research is sourced from secondary data obtained from documents, journals related and in line with physical disabilities and life skills education for physical disabilities. The result of this literature review is that empowerment of disabled groups must be carried out to increase participation in various fields of social life with adequate and relevant work skills. Skill enhancement is provided to gain accessibility for persons with disabilities, one of which is through non-formal education programs, namely life skills education. Vocational rehabilitation as a form of life skills education through non-formal education is carried out by providing services in the form of skills training activities that aim to cultivate, develop and increase the potential possessed by persons with disabilities, especially persons with physical disabilities.

Facilitators of and Barriers to Adherence to Dietary Interventions Perceived by Women With Multiple Sclerosis and Their Support Persons.

People with multiple sclerosis (MS) frequently report implementing dietary strategies as part of their personal wellness programs; however, little is known about the perceived themes of healthy behavior change in people with MS. Semistructured one-on-one interviews were conducted with 20 women with MS enrolled in 2 different restrictive dietary intervention studies and their 18 self-identified support persons consisting of partners and adult children. Interviews were transcribed, coded, categorized, and then grouped into summative themes. The frequency of issues being mentioned as facilitators of or barriers to diet adherence was evaluated to identify possible differences in perceived experiences between women with MS and their support persons during the studies. Five qualitative themes were identified: (1) personal motivation, (2) diet components, (3) time, (4) support, and (5) resource access. Major facilitators of dietary adherence were positive support from support persons and study staff, access to resources, symptom improvement, and personal motivation. Major barriers included the novelty of the study diet, lack of cooking skills, no change in or worsening of symptoms, lack of diet knowledge, and food preferences and temptations. Symptom severity was more frequently reported as a barrier to study diet adherence among participants with secondary progressive MS. Methods to enhance personal motivation and ensure positive support from support persons and study staff may improve study diet adherence. Due to the unique challenges faced by people with MS, future studies should tailor interventions to their unique MS cohort to increase diet adherence.

Kesetaraan Di Muka Hukum Bagi Penyandang Disabilitas (Analisis Putusan Nomor 28/Pid.B/Pn.Skh/2013)

The right on the same position on the law means that every citizens including disabilities persons have the same change to use their rights regulated by the institution. Indonesia government has signed Convention on the Rights of Persons with Disabilities in March 30, 2007 in New York. That even shows the strong intention of Indonesia country to respect, save, fulfill, and develop the disabilities persons’ right to fulfill the welfare of the disabilities persons. There is a case happened in Sukaharjo in the decision No. 18/Pid.B/PN.SKH/2013 about a crime defeated the disabilities person. This study employed library research design. The finding shows that the judges in the decision Nomor 28/Pid.B/PN.SKH state that the defendant convicted 8 years 6 months. The decision can be used as jurisprudence for other judges in examining the same case in order to avoid criminal disparity. In a further development, the criminal appeals to the High Court in Central Java, and in the High Court, Decision No. 244 / Pid 2013 / P.T.Smg actually strengthens the High Court Decision Sukoharjo with 10 years prison. Based on this decision it should increase the capacity of law enforcement agencies in the fulfillment of the right to a fair trial for persons with disabilities must be done. It aims to introduce the concept of disability to law enforcement officials, provide an understanding of human rights, especially the rights of persons with disabilities to law enforcement officials, as well as provide expertise (skills) to law enforcement authorities on the way and methods to fulfill the accessibility of persons with

Panophthalmitis secondary to retained intraocular foreign body amidst a national lockdown during the COVID-19 pandemic: A case series and review of literature

IntroductionIntraocular foreign bodies (IOFBs) can be serious as they may result in vision-threatening ocular inflammations and even loss of the eye. Delay in presentation or treatment by more than 24 hours from the time of injury results in a poor prognosis. In penetrating wounds, microorganisms enter the eye through penetrating objects. Both bacterial and fungal organisms are responsible for causing panophthalmitis. At the ocular level, these microorganisms produce irreversible damage which includes keratitis, uveitis, hypopyon, vitreous abscesses, retinal necrosis, detachment, and, finally, panophthalmitis. Case scenariosIn this case series, we report three cases of IOFB presenting with panophthalmitis secondary to delay in seeking medical attention. In our cases, there was a delay in the presentation by more than 24 hours of trauma. All cases had panophthalmitis at the time of presentation. In two cases, the causative organism was coagulase-negative staphylococci and in one case it was staphylococcus. Initially, we planned to manage them with intravitreous, intravenous and topical antibiotics till the inflammation subsides, then IOFB removal surgeries were planned. However, in two cases, the clinical presentation worsens with scleral necrosis. Therefore, they had to undergo evisceration. In one case, the antibiotics therapy was enough without IOFB removal surgery to manage her symptoms. All cases recovered uneventfully after the interventions. Discussion/ConclusionIn developing nations, like Nepal, transportation barriers can affect a person's access to health care services. This can be clearly explained from this case series as limited transportation options in rural regions are a major factor for all patients' delayed presentation to the hospital during the time of national lockdown in the second wave of the COVID-19 pandemic. The concerned authority must pay attention to solving such social determinants of health.

Analytical Review of Digital Accessibility Services on Official Sites of the World’s Best Universities

The paper discusses the problem of e-learning accessibility for persons with disabilities. Development of e-learning content accessible to all students is gaining special relevance in the context of global trends in higher education related to the massive transition of learning to distance and hybrid formats. Based on the analysis of the official websites of 25 world’s top universities (according to the QS World University Rankings 2021), data on university digital accessibility services were systematized. The data search was carried out by total browsing of university sites’ structure and headings and by keywords. Data on 14 checklist categories were registered. Signs of administrative and project activities in the field of digital accessibility were found for 20 universities (80%), among which 10 (40%) have specialized structural subdivisions for digital accessibility. The content of digital accessibility web services contains data on the following topics: training in digital accessibility for educational content for authors and developers (14 university sites – 56%); a guide for authors (15–60%) and web developers (12–48%); consulting and assistance for authors and web developers (17–68%); accessibility examination (5–20%); legal norms (11–44%) and accessibility standards (16–64%); accessibility testing guide (16–64%); procurement requirements for accessible web products and services (8–32%); frequently asked questions (6–24%), etc. Based on the results of the analysis, the model of university digital accessibility services was developed and corresponding web site was published. It seems important to create similar web resources and corresponding structural subdivisions in universities of the Russian Federation, as well as to approve the intra-university local acts regulating the mandatory fulfillment of digital accessibility requirements in the development of educational content and the procurement of digital products and services. GOST R 52872-2019, based on WCAG 2.1, should be used as the basis for local legal regulations.

Ultrasound Use by Upper Extremity Surgeons in 2020: A Survey of ASSH Members.

The use of musculoskeletal ultrasound (US) among hand surgeons appears to be increasing. The purpose of this study was to determine the utilization patterns and attitudes regarding US among American Society for Surgery of the Hand (ASSH) members in 2020 as well as the changes in usage patterns since a previous survey in 2015. In 2020, an updated and expanded 27-question survey was distributed to 4852 members of the ASSH. Questions assessed respondent demographics, training, and practice patterns, and access, utilization, training, and opinions pertaining to US. A total of 418 surveys (8.6%) were analyzed. Compared to 2015, there was an increase in the percentage of respondents using US for diagnostic purposes (51%-68%), as well as having personal access to US machines (43% to 58%). US use to assist in diagnosing carpal tunnel syndrome increased from 19% to 27%. The most common reason for using US was convenience and practice efficiency, while the most common reasons for not using US was no machine access. In 2020, 33% of respondents performed US-guided injections. Compared to 2015, the majority of responding upper extremity surgeons now have personal access to US machines. Utilization of diagnostic US appears to be increasing, and two-thirds of respondents believed that US use will continue to increase among upper extremity surgeons.

Large animal veterinarians' knowledge, attitudes, and practices regarding livestock abortion-associated zoonoses in the United States indicate potential occupational health risk.

To understand large animal veterinarians' knowledge of select zoonotic diseases that cause livestock abortions and identify barriers to using personal protective equipment (PPE). A convenience sample of 469 veterinarians currently working with livestock. We sent an electronic survey invitation to large animal veterinarians through various veterinary organizations. Respondents answered questions addressing knowledge and prior experience with select abortion-associated zoonotic diseases, resources available for infection control, attitudes and barriers to PPE use, and demographics. Median participant age was 49 years (range, 22 to 82 years), and 54% (235/438) were male. Half of veterinarians (185/348) were contacted 5 or fewer times per year to consult on livestock abortions. No veterinarians surveyed answered all questions on zoonotic disease transmission correctly. Personal protective equipment access varied, from 99% (289/290) having access to gloves to 20% (59/290) having access to respirators. Concerns for spreading disease to other animals (136/289 [47%]) and to other humans (108/287 [38%]) ranked as the most common reported motivators for PPE use. Reported barriers to PPE use among survey participants were the inconvenience of taking PPE into the field (101/286 [35%]) and the inconvenience of wearing PPE (97/286 [34%]). Access to PPE was not correlated with PPE use. Surveyed veterinarians had limited knowledge of transmission of select abortion-associated zoonotic diseases. Incomplete understanding might lead to inappropriate PPE selection, preventable disease exposure, or missed opportunities for client education. Inconvenience was a primary reason PPE was not used.

Whole Genome Sequencing, Focused Assays and Functional Studies Increasing Understanding in Cryptic Inherited Retinal Dystrophies.

The inherited retinal dystrophies (IRDs) are a clinically and genetically complex group of disorders primarily affecting the rod and cone photoreceptors or other retinal neuronal layers, with emerging therapies heralding the need for accurate molecular diagnosis. Targeted capture and panel-based strategies examining the partial or full exome deliver molecular diagnoses in many IRD families tested. However, approximately one in three families remain unsolved and unable to obtain personalised recurrence risk or access to new clinical trials or therapy. In this study, we investigated whole genome sequencing (WGS), focused assays and functional studies to assist with unsolved IRD cases and facilitate integration of these approaches to a broad molecular diagnostic clinical service. The WGS approach identified variants not covered or underinvestigated by targeted capture panel-based clinical testing strategies in six families. This included structural variants, with notable benefit of the WGS approach in repetitive regions demonstrated by a family with a hybrid gene and hemizygous missense variant involving the opsin genes, OPN1LW and OPN1MW. There was also benefit in investigation of the repetitive GC-rich ORF15 region of RPGR. Further molecular investigations were facilitated by focused assays in these regions. Deep intronic variants were identified in IQCB1 and ABCA4, with functional RNA based studies of the IQCB1 variant revealing activation of a cryptic splice acceptor site. While targeted capture panel-based methods are successful in achieving an efficient molecular diagnosis in a proportion of cases, this study highlights the additional benefit and clinical value that may be derived from WGS, focused assays and functional genomics in the highly heterogeneous IRDs.

The Role of Health Kiosks: Scoping Review.

BackgroundHealth kiosks are publicly accessible computing devices that provide access to services, including health information provision, clinical measurement collection, patient self–check-in, telemonitoring, and teleconsultation. Although the increase in internet access and ownership of smart personal devices could make kiosks redundant, recent reports have predicted that the market will continue to grow.ObjectiveWe seek to clarify the current and future roles of health kiosks by investigating the settings, roles, and clinical domains in which kiosks are used; whether usability evaluations of health kiosks are being reported, and if so, what methods are being used; and what the barriers and facilitators are for the deployment of kiosks.MethodsWe conducted a scoping review using a bibliographic search of Google Scholar, PubMed, and Web of Science databases for studies and other publications between January 2009 and June 2020. Eligible papers described the implementation as primary studies, systematic reviews, or news and feature articles. Additional reports were obtained by manual searching and querying the key informants. For each article, we abstracted settings, purposes, health domains, whether the kiosk was opportunistic or integrated with a clinical pathway, and whether the kiosk included usability testing. We then summarized the data in frequency tables.ResultsA total of 141 articles were included, of which 134 (95%) were primary studies, and 7 (5%) were reviews. Approximately 47% (63/134) of the primary studies described kiosks in secondary care settings. Other settings included community (32/134, 23.9%), primary care (24/134, 17.9%), and pharmacies (8/134, 6%). The most common roles of the health kiosks were providing health information (47/134, 35.1%), taking clinical measurements (28/134, 20.9%), screening (17/134, 12.7%), telehealth (11/134, 8.2%), and patient registration (8/134, 6.0%). The 5 most frequent health domains were multiple conditions (33/134, 24.6%), HIV (10/134, 7.5%), hypertension (10/134, 7.5%), pediatric injuries (7/134, 5.2%), health and well-being (6/134, 4.5%), and drug monitoring (6/134, 4.5%). Kiosks were integrated into the clinical pathway in 70.1% (94/134) of studies, opportunistic kiosks accounted for 23.9% (32/134) of studies, and in 6% (8/134) of studies, kiosks were used in both. Usability evaluations of kiosks were reported in 20.1% (27/134) of papers. Barriers (e.g., use of expensive proprietary software) and enablers (e.g., handling of on-demand consultations) of deploying health kiosks were identified.ConclusionsHealth kiosks still play a vital role in the health care system, including collecting clinical measurements and providing access to web-based health services and information to those with little or no digital literacy skills and others without personal internet access. We identified research gaps, such as training needs for teleconsultations and scant reporting on usability evaluation methods.

Openness and Preparedness of Senior FFA Members Toward Technology in Agriculture

School-Based Agricultural Education provides students the opportunity to engage with new and emerging agricultural technologies. Employers value employability skills such as openness, preparedness, and adaptability. However, the Agricultural Education literature is limited on the preparation of students in these skills. We conducted a descriptive study to explore how open and prepared 2020-2021 high school senior members of the National FFA Organization were for 10 selected new and emerging Agriculture, Food, and Natural Resources (AFNR) technologies. Additionally, the study evaluated the methods through which members learned about technology. An overview of students’ contact with the 10 selected technologies and their experiences using these technologies contributes to an understanding of methods used in the classroom and how adaptable students may be for emerging technologies in the future. The study occurred in fall 2020 with 1,528 respondents completing the online survey. Almost all respondents reported personal access to a smart phone and computer at home with internet access. Respondents reported use or contact with the 10 selected technologies with that contact most often being in the agriculture classroom/laboratory. Respondents reported self-perceived very strong adaptability, high openness, and average preparedness. This could imply study respondents are open to new and emerging AFNR technologies but not prepared.

Impact of Malaria Diagnostic Technologies on the Disease Burden in the Sub-Saharan Africa.

Worldwide, transmission of emerging and reemerging malaria infections poses a significant threat to human health in the Sub-Saharan Africa, one that can quickly overwhelm public health resources. While the disease burden of malaria in the Sub-Saharan Africa appears to be on a gradual decline, it is characterized by spatial and temporal variability occasioning a sorry state for the Global South Countries. New evidence on long-term complications of malaria heightens our awareness of its public health impact. Given the likelihood of misdiagnosis, and the unknown levels of malaria transmission across different landscapes, many missed opportunities for prevention occur. Africa's population growth, unplanned urbanization, habitat destruction, and trans-border travel are contributing to a rise in the calamitous epidemiology of malaria. Despite empirical statistics demonstrating a downward trend in the malaria disease burden attributable to the scale-up of multiple control strategies, including new diagnostic technologies, malaria remains a global threat to human health in Sub-Sahara Africa. Malaria is a severe public health threat globally, despite several advancements and innovations in its control. Six species of the genus Plasmodium including Plasmodium malariae, Plasmodium falciparum, Plasmodium cynomolgi, Plasmodium knowlesi, Plasmodium ovale, and Plasmodium vivax are known to infect humans. However, greatest disease burden and fatalities are caused by Plasmodium falciparum. Globally, about 3 billion individuals are at risk of contracting malaria disease every year, with over 400,000 fatalities reported in the Sub-Saharan Africa. World Health Organization (WHO) 2018 malaria report indicated that approximately 405,000 mortalities and 228 million cases were reported worldwide, with Africa carrying the highest disease burden. Over the last decade, there has been a significant decline in malaria deaths and infections, which may be related to the availability of effective diagnostic techniques. However, in certain areas, the rate of decline has slowed or even reversed the gains made so far. Accurate diagnosis, adequate treatment, and management of the disease are critical WHO-set goals of eliminating malaria by 2030. Microscopy, rapid diagnostic tests (RDTs), nucleic acid amplification tests (NAATs), and biosensors are all currently accessible diagnostic methods. These technologies have substantial flaws and triumphs that could stymie or accelerate malaria eradication efforts. The cost, ease, accessibility, and availability of skilled persons all influence the use of these technologies. These variables have a direct and indirect ramification on the entire management portfolio of patients. Despite the overall decline in the malaria disease burden driven partly by new diagnostic technologies, a sobering pattern marked by limited number of studies and spatial as well as temporal heterogeneity remains a concern. This review summarizes the principle, performance, gaps, accomplishments, and applicability of numerous malaria diagnostic techniques and their potential role in reducing the malaria disease burden in Sub-Saharan Africa.

Mechanism of Internet of Things (IoT) Integrated with Radio Frequency Identification (RFID) Technology for Healthcare System

Radio frequency identification (RFID) technology has already demonstrated its use. RFID is used in many productions for different applications, for example, apparatus chasing, personal and vehicle access panels, logistics, baggage, and safety items in departmental stores. The main benefits of RFID are optimizing resources, quality customer service, improved accuracy, and efficient business and healthcare procedures. In addition, RFID can help to recognize appropriate information and help advance the probability of objects for certain functions. Nevertheless, RFID components need to be studied for use in healthcare. Antennas, tags, and readers are the main components of RFID. The study of these elements provides an understanding of the usage and integration of these components in healthcare environments. The security of the patient is now a global alarm for public health, particularly among older people who need integrated and technologically integrated physiological health monitoring systems to monitor medical needs and manage them. This paper proposes using Internet of Things (IoT) and RFID tags as an effective healthcare monitoring system. In this method, we utilize RFID dual-band protocols that are useful for identifying individual persons and are used to monitor body information using high frequency. The patient’s physiological data are monitored and collected by sensors to recognize the patient, using an RFID tag. The IoT-based RFID healthcare provides the elderly and people with physiological information. The aim is also to secure patient health records using the signing algorithm based on the hyperelliptic curve (HEC) and to provide the physician with access to health information for patients. Furthermore, the confidentiality of the medical records for patients of variable length is provided. The evaluation reveals the algorithm proposed for optimum health care with different genus curves.

Study Protocol: Cannabis in the Closet? Older Persons' Perceptions of Stigma and their Influence on Use and Access to Medicinal Cannabis

Background: Cannabis has been used for medicinal purposes for millennia. Stigma associated with cannabis use may influence older persons access to cannabis, information seeking about cannabis, and/or use of cannabis. Scant research has sought to examine the impact of older persons’ perceptions of stigma on the ways they learn about and use medicinal cannabis, with important implications for their health.
 Methods/Design: In this qualitative descriptive study, we will seek older persons’ information needs and challenges accessing cannabis from older persons and professionals who work in the cannabis industry. Using open ended questions, we will survey and interview older persons who use cannabis or are considering using it about their perceptions of stigma, information seeking, choice of cannabis product, and preferred vendor. Professionals who work with cannabis will be interviewed for their experiences with older persons seeking information about and access to cannabis.
 Discussion: Findings will identify what information related to medicinal cannabis use older Canadians most urgently need, shed light on any stigma they fear and/or experience when searching for such information, and inform the development of information products and knowledge mobilization strategies tailored to older Canadians’ knowledge needs.

Use of complementary and integrative health in cancer pain management among patients undergoing cancer treatments: a qualitative descriptive study.

Pain is a common symptom in patients undergoing cancer treatment. Despite recommendations for the stronger integration of complementary and integrative health (CIH) in cancer pain management, little is known about the individual experience of using this approach for cancer pain, particularly in certain populations such as African Americans. This study aimed to describe the experiences of using CIH for pain in African American and White patients with cancer undergoing cancer treatments. A secondary analysis of qualitative descriptive data from a subsample of patients with cancer in a parent study of their illness concerns was employed. Atlas.ti 8.0 was used for data management and qualitative analysis. Counts of participant-endorsed themes were tabulated to discern differences in themes by group. Of 32 participants (16 African American, 16 White), 22 reported CIH usage for cancer pain management, with equal distribution between groups (11 each). Three themes emerged: Approach to, Reasons for, and Barriers to CIH Use. Psychological approaches were most common (n = 15). Nutritional, physical, and combination approaches were less common and more often employed by White participants. Reasons for CIH use were to reduce opioid consumption or for an opioid adjuvant. Personal limitations and access issues contributed to Barriers to CIH use. Both African American and White patients used CIH for pain management while undergoing cancer treatments. However, some preferential differences in CIH approaches by race surfaced. Further research into these differences may uncover new ways of addressing disparities in cancer pain management with CIH.

A qualitative study of services accessibility for indigenous persons who use injection drugs across three communities in the United States

Aims: This study concerns the perspectives of Indigenous persons who use injection drugs (IPWIDs) and key stakeholders across multiple sectors regarding healthcare service and treatment accessibility in the United States. Methods: Sixty in-depth interviews were undertaken with selected participants (30 people who use injection drugs and 30 stakeholders) across three non-urban locations in the United States. An inductive analytic approach was used to explore perspectives regarding healthcare accessibility gaps. Results: IPWIDs described injecting stimulants, opioids, and diverted medications for opioid use disorder, as well as having unstable access to sterile syringes. Often, the most accessible treatment for IPWID substance use was engagement with punitive aspects of the criminal justice system. While local health and social services were described as providing limited or inadequate services for IPWIDs, human capital deficiencies in those agencies and institutions often reinforced barriers to accessibility for IPWIDs, further aggravating the epidemics of Hepatitis C Virus infection and overdose risk in Indigenous communities. Conclusions: Decolonizing approaches to IPWID-centered services are urgently needed to reduce disparities in transmission of infectious diseases and other health consequences of injection drug use among American Indian people. Potential pathways forward include moving away from punitive treatment of IPWIDs by the criminal justice system and toward local, tribally-centered, culturally appropriate treatment models. We identify an urgent need to provide reliable and local access to sterile injection equipment and opioid substitution treatment on or near reservations.

Business models transformed by digitalization in contemporary art museums and galleries

In the 21st Century, the common features of the developing digital technology are compressed information, accelerated information management, big data, multiple interaction, personalization and uninterrupted access and convergence. These features are seen as factors that accelerate access to information, reduce some communication and cost expenses economically, speed up sales and marketing, provide visibility to institutions, and increase ideas and sharing. With the effects of digital technology Contemporary art museums and galleries have experienced digitalization processes in order to maintain their existence and achieve their goals. Digitalization is not limited to being a technical application, but it is a process that transforms contemporary art institutions as a whole, especially in communication, institutionalism, branding, marketing, finance and sustainability. Therefore, digital technology requires to be available to institutions. Being a contemporary art institution requires being intellectually and technologically renewed in institutional, managerial and communicative terms. The mission and sustain-ability of art and art institutions should be ensured in harmony with technology. Therefore, new business models have been required in the digitalization processes in art institutions and the need for changing business models will increase as technology develops. Purpose of the study: To identify the new business models of contemporary art museums and galleries, and in parallel, the features they need in human resources, and to raise awareness on this issue. In this study, the hybrid structure of new business models needed in contemporary art institutions has been revealed as a whole. In the study, it has been revealed based on the examples and the viewpoints of authorized persons that, managerial digital strategies in contemporary art museums and galleries should contain the distinction specific to art. The main result that emerged from the interviews is the hybrid structures of the new business models needed by contemporary art museums and galleries in the digital age, blended with digital technology and the knowledge of art management.

Is the world ready for gene therapy?

To prepare for the introduction of gene therapies in haemophilia care, healthcare frameworks for evaluation and valuation will need to evolve to address the unique requirements of current and future innovations for treating this rare disease. The papers in this supplement provide an insightful and comprehensive state-of-the-art assessment of these requirements and challenges. In terms of evaluation, the definition of a patient-defined value framework that captures multi-dimensional, patient-centered outcomes is an important first step for determining the full benefit of gene therapy for persons with haemophilia. In terms of valuation and rewards for innovation, health systems will need to develop alternative payment models for risk-sharing that will allow payers and society to address uncertainties about the ultimate clinical and economic value of these innovations. And health technology assessment authorities will need to exercise greater flexibility in evidence requirements given the unique features of data collection for a potentially curative therapy for a rare disease with long-term uncertainties about durability of impact. Collaboration among stakeholders will be essential for developing the critical evidence requirements and providing the incentives needed to achieve sustainable budgets and broad access for persons with haemophilia worldwide.

AKSES PENYANDANG DISABILITAS TERHADAP PEKERJAAN: KAJIAN LITERATUR

According to data from the ILO, the International Labor Organization, 82 percent of people with disabilities in the world live in developing countries and live below the poverty line. They find it difficult to get various accesses including in the fields of employment, health, information, politics. Opportunities for persons with disabilities to find work are lower than those of non-disabled persons. This article discusses the access of persons with disabilities in Indonesia to work. The method used for this writing is a literature review through the Google Scholar database. From the results of the study, it is known that there have been efforts to provide access for persons with disabilities in the field of employment, but the level of participation of persons with disabilities is still there. This is due to, among other things, the low capacity of persons with disabilities, as well as the lack of access to information on time availability.