AimThis study examines the relative influence of personal resilience, social support and organisational support in reducing COVID‐19 anxiety in front‐line nurses.BackgroundAnxiety related to the COVID‐19 pandemic is prevalent in the nursing workforce, potentially affecting nurses’ well‐being and work performance. Identifying factors that could help maintain mental health and reduce coronavirus‐related anxiety among front‐line nurses is imperative. Currently, no studies have been conducted examining the influence of personal resilience, social support and organisational support in reducing COVID‐19 anxiety among nurses.MethodsThis cross‐sectional study involved 325 registered nurses from the Philippines using four standardized scales.ResultsOf the 325 nurses in the study, 123 (37.8%) were found to have dysfunctional levels of anxiety. Using multiple linear regression analyses, social support (β = −0.142, p = .011), personal resilience (β = −0.151, p = .008) and organisational support (β = −0.127, p = .023) predicted COVID‐19 anxiety. Nurse characteristics were not associated with COVID‐19 anxiety.ConclusionsResilient nurses and those who perceived higher organisational and social support were more likely to report lower anxiety related to COVID‐19.Implication for Nursing ManagementCOVID‐19 anxiety may be addressed through organisational interventions, including increasing social support, assuring adequate organisational support, providing psychological and mental support services and providing resilience‐promoting and stress management interventions.