This study examines the impact of digitalization on the formation and development of the regulatory subsystem, which is a key component of the human psyche. The findings reveal that digitalization has a significant and complex influence on this subsystem, operating at two complementary levels: analytical and structural. The analytical level reflects a profound decrease in the development of the subsystem’s individual components, including essential regulatory processes and their associated qualities. This decline raises concerns about the capacity of individuals to effectively manage their cognitive and emotional resources in a digital context. In contrast, the structural level involves meaningful transformations in the organization, structuring, and integration of these components. These changes indicate a shift in how the regulatory subsystem operates, suggesting that digitalization is reshaping the very foundation of psychological regulation. As a result of this complex influence, a new phenomenon emerges, referred to as the syndrome of reduced personality regulation. This syndrome holds significant implications for overall personality development and regulatory potential, sharing similarities with previously identified syndromes of decreased cognition and metacognition. The structural transformations in the regulatory subsystem, influenced by digitalization, primarily manifest as changes in the degree of organization and integration, rather than qualitative alterations. The qualitative aspects remain invariant and resist the pervasive effects of digitalization, suggesting the subsystem’s resilience that may offer avenues for further exploration and intervention.