Two permeable parking lots and one impervious concrete pavement were constructed in Shanghai to study the hydrological and water quality performance of permeable interlocking concrete pavements (PICP) with different base course materials. The hydrological performance and water quality of the influent and effluent under actual precipitation conditions in 2018 were monitored, and the two PICPs used cement-stabilized crushed stones (PICP1) and crushed stones (PICP2) as the base course, respectively. Results show that the annual total volume reduction rates of PICP1 and PICP2 are 37.0% and 38.7%, respectively. The peak flow reduction rate and the time to the peak flow of PICP1 are slightly better than PICP2. PICP1 has better transformation efficiency on NH4+-N in comparison to PICP2, and the release of NO3--N occurs in both PICPs. Moreover, PICP1 has lower effluent concentrations than PICP2 on pollutants like TSS, TP, PP, and DP. The PICP with cement-stabilized crushed stones as base course is helpful to improve the hydrological performance and water quality of the effluent.