Global change affected by multiple factors, the consequences of which continue to be far-reaching, has the characteristics of large spatial scale and long-time scale. The demand for Earth observation technology has been increasing for large-scale simultaneous observations and stable global observation over the long-term. A Moon-based observation platform, which uses sensors on the nearside lunar surface, is considered a reasonable solution. However, owing to a lack of appropriate processing methods for optical sensor data, global change study using this platform is not sufficient. This paper proposes two optical sensor imaging processing methods for the Moon-based platform: area imaging processing method (AIPM) and global imaging processing method (GIPM), primarily considering global change characteristics, optical sensor performance, and motion law of the Moon-based platform. First, the study proposes a simulation theory which includes the construction of a Moon-Sun elevation angle model and a global image mosaicking method. Then, coverage images of both image processing methods are simulated, and their features are quantitatively analyzed. Finally, potential applications are discussed. Results show that AIPM, whose coverage is mainly affected by lunar revolution, is approximately between 0% and 50% with a period of 29.5 days, which can help the study of large-scale instant change phenomena. GIPM, whose coverage is affected by Earth revolution, is conducive to the study of long term global-scale phenomena because of its sustained stable observation from 67°N-67°S on the Earth. AIPM and GIPM have great advantages in Earth observation of tripolar regions. The existence of top of the atmosphere (TOA) albedo balance line is verified from the GIPM perspective. These two imaging methods play a significant role in linking observations acquired from the Moon-based platform to Earth large-scale geoscience phenomena, and thus lay a foundation for using this platform to capture global environmental changes and new discoveries.