Coaches and analysts face a significant challenge of inaccurate estimation when analyzing Men's 100 Meter Sprint Performance, particularly when there is limited data available. This necessitates the use of modern technologies to address the problem of inaccurate estimation. Unfortunately, current methods used to estimate Men's 100 Meter Sprint Performance indexes in Iraq are ineffective, highlighting the need to adopt new and advanced technologies that are fast, accurate, and flexible. Therefore, the objective of this study was to utilize an advanced method known as artificial neural networks to estimate four key indexes: Accelerate First of 10 meters, Speed Rate, Time First of 10 meters, and Reaction Time. The application of artificial neural networks in the sports industry in the Republic of Iraq is crucial to ensure successful players. In this study, an artificial neural network model was built to predict Men's 100 meter indexes. Several factors related to the construction of artificial neural networks were studied, including network architecture and internal factors and their impact on the performance of the models. As a result, four easy equations were developed to calculate the four key indexes. The findings of the study indicate that these networks can predict Men's 100 Meter indexes with a high degree of reliability 98.034% and accounting coefficients R = 0.9143.