People Of Different Ages Research Articles

The impact of different ages of onset on cardiopulmonary function in Chinese patients with systemic lupus erythematosus

Abstract Background Despite being most prevalent in adults, systemic lupus erythematosus (SLE) can also be diagnosed in teenagers and older adults. The levels of sex hormones in people of different ages were varied and the clinical features and disease activity of SLE were affected by hormonal changes. Whether the ages of onset impact the cardiopulmonary manifestations was not well explored in patients with SLE. Purpose The purpose of this registry was to investigate the difference in clinical features and cardiopulmonary performance in patients with childhood-onset SLE, or young adulthood onset SLE and adulthood-onset SLE. Methods patients aged 18 or older and meeting the diagnostic standards of SLE which were established by the ACR in 1997 were included in this study. Patients were divided into childhood-onset (< 18 years old ), young adulthood-onset (18∼35 years old ), and adulthood-onset groups (>35 years old ) based on the different ages at diagnosis. Clinical and demographic data were collected from the clinical management system. In addition, laboratory tests, six-minute walk test (6MWT), electrocardiography, transthoracic echocardiography, and pulmonary function were performed for all patients. Results 1054 patients with SLE were enrolled in this study. The adulthood-onset group has a higher systolic blood pressure, shorter 6MWTD, and a higher proportion of chronic kidney disease compared to the other two groups (p<0.05). In contrast, mixed connective tissue disease (MCTD) has occurred more frequently in the childhood-onset group (14.5%) compared to the other two groups (p<0.05). And thus, immunosuppressive was used more frequently in the childhood-onset group than in the other two groups (p<0.05). The left ventricular diastolic function was evaluated by the ratio of peak early to late diastolic filling velocity (E/A ratio). The E/A ratio was significantly reduced in the adulthood-onset group (1.1±0.0) than in the childhood-onset group (1.4±0.0) and the young adulthood-onset group (1.3±0.0). Moreover, patients in the adulthood-onset group presented with a larger right atrial diameter (4.4±0.0) than the childhood-onset group (4.2±0.0) and the young adulthood-onset group (4.2±0.0). The adulthood-onset group (17.4%) has a high proportion of "pulmonary hypertension" which was evaluated based on the guideline established by the European society of cardiology. An impaired forced vital capacity (FVC) and forced expiratory flow at 75% of FVC (FEF75%) were observed in the adulthood-onset group compared to the other two groups (p<0.05). Conclusions This registry has demonstrated that different ages of onset could impact the clinical and cardiopulmonary performance in Chinese patients with SLE. Patients in the adulthood-onset group presented higher blood pressure, shorter 6MWT, a higher proportion of chronic kidney disease, and impaired pulmonary function compared to the other two groups.Comparisons of clinical and cardiopulmo

Ageism as a problem of the younger generation

Aim. To analyze the experience of developing and testing a targeted program for improving the age-related vitality and quality of life of people in older age groups through the development of intergenerational connections, which consists of involving younger schoolchildren and their parents in voluntary work, increasing the knowledge of younger schoolchildren in aging and old age and reducing the ageism of older people.Material and methods. This prospective cohort study consisted of 3 stages. For the study, original questionnaires were used to assess the knowledge in the field of aging processes and determine the degree of ageism among people of different ages. The study involved 138 respondents — primary school students, parents of schoolchildren, and teachers.Results. The Project "Gerontological Education of Grade Schoolers" was developed and implemented, which included separate blocks. Spending time together benefits the level of good manners among grade schoolers as follows: the high level of good manners increased by 30,6%, while the average and low levels decreased by 13,9% and 66,7%, respectively. The interpretation of 4-year survey data (2019-2023) indicate that the developed system was successfully tested.Conclusion. For the first time, a targeted program has been developed for older age groups through the development of intergenerational connections, which consists of involving grade schoolers and their parents in volunteer activities.

The relationship between political procedural justice and attitudes toward the political system: A meta‐analysis

AbstractA positive relationship between assessments of procedural justice and attitudes toward the political system has been identified in many studies of various countries. To quantify this relationship, a meta‐analysis was conducted on 69 samples from 50,814 respondents, reported in 37 manuscripts between 1981 and 2021. We found positive correlations between assessments of procedural justice and attitudes toward politicians, political institutions, and the political system in people of different ages and in countries with different political regimes. These positive correlations exist in real and hypothetical situations with various levels of authority. However, two factors moderated the association between the assessment of procedural justice and political attitudes. First, procedural justice as a set of norms is more strongly related to attitudes toward the system than procedural justice as a generalized assessment is. Second, the assessment of procedural justice is more strongly associated with attitudes toward political institutions and the system than attitudes toward the procedures and decisions. Moreover, the percentage of heterogeneity in the obtained models is fairly high; categorical moderators explain 43% of the variance of the effects obtained. The results should therefore be interpreted with consideration of this substantial heterogeneity in the correlations' sizes.

Perceptions and Attitudes of Parents and Teachers of Students Within and Outside the Chinese System Towards the LGBT+ Community

Sexual minority(LGBT+) is a relatively controversial topic, especially in China. Globally, LGBT+ is still a vulnerable group, and there are still cases of bullying and verbal abuse in various countries because of their sexual orientation, and people have mixed opinions about it. But with the development of the internet, people have become more aware of ta it and opinions have changed. And for the official and the general public, the official t attitude is significantly more neutral and conservative. And people with different education have different views on LGBT, and overseas students are significantly more open to the influence of western culture. For people of different ages, the different perceptions they receive can also lead to differences in perceptions. In this paper, we use questionnaires and references to literature and laws to derive the official and private attitudes, and then compare and analyze the perceptions of people of different ages and different educational levels about the LGBT+ community.

How Pandemic-related Misinformation Affect China after Zero-Covid

Since China abandoned its long-held zero-Covid policy and eased its Covid-19 restrictions in December 2022, much misinformation about Covid-19 treatment methods and precautions has been widely spread and fermented on various social media, seriously misleading the public and causing specific effects on society. Based on this, this study interviewed several people of different ages and occupations who experienced this period, learning about their personal experiences and feelings about pandemic-related misinformation. To explore how news audiences perceive and respond to misinformation in the specific context of the pandemic outbreak, some potential economic and social impacts brought by it, as well as attempt to provide some insights into the fight against misinformation in China and the world.

Examining the impact of social media advertising using ANOVA analysis

SummarySocial media has become a significant part of daily life and nowadays it has started to turn out to be common practice for consumers and companies to employ social media to form, establish, and connect relationships. In addition, social media is based on web and mobile‐based technologies for creating highly interactive paradigms by which communities and individuals co‐create, share, modify and discuss user‐generated content. However, it is never easy for businesses to create social media advertising that attracts people and encourages them to buy their products. This article intends to present a statistical analysis that focuses on social media marketing among people of different ages. Six categories—personal profile, usage, assessment, higher‐order data, trustworthiness, and elements of social media ads—are included in the analysis of social media marketing. The initial phase focuses on questionnaire preparation depending on social media advertising. Subsequently, the planned questionnaire is collected from diverse respondents at various educational levels utilizing a Google form. Then, these respondents' responses are collected for examination. To determine whether the outcomes of the experiment are meaningful, the evaluation in this piece of study is based on an ANOVA analysis.

CITY-ORIENTED POLITICS: SOCIAL MOVEMENTS OF NEW URBANISM AND MUNICIPALITY ON THE WAY TO INNOVATION

The article discusses the latest trends related to global transformations in the context of the introduction of a new global “place-based politics”. The author draws attention to the fact that due to the technological, demographic and migration processes that lead to large-scale urbanization and the concentration of the Earth’s population in cities, the recognition of the comfort of the city, oriented to the needs of the social and the needs of people of different ages, has become a privileged object of such a global and national policy. It is noted that urbanization and the formation of global cities – metropolises, agglomerations, etc. – leads to excessive concentration of production, uneven global settlement of territories, excessive immigration load on the centres of industrial growth, which in turn causes problems of global social inequality, which is also manifested in the hierarchy cities, and in the internal social hierarchy in cities. The author points out that social movements: New Municipalism and New Urbanism have become global social movements that embody innovations to help solve the above problems. Therefore, the purpose of the study is to determine the main proposals of new urbanism and new municipalism for the implementation of “place-based politics” in the city as a centre of innovation. The article examines the historical features of the development of both movements built on the slogans: “democracy begins where you live” and “right to the city”. The article defines the goals and principles of activity of organizations that are participants in these movements, and also examines the scientific and methodological discourse formed around the development of these movements. In particular, the author presents an interpretation of the “nature” of municipalism, analyzes three models of municipalism, according to Matthew Thompson’s typology. In the conclusions, the author points out that planning ideas and successful projects of New Urbanism promote tools for quality urban planning for the sake of people in the conditions of global reconstruction of urban networks for the purpose of deconcentration and demonopolization of resources and investments. The ideas of New Municipalism promote tools to ensure self-organization at the city level, tools of social solidarity interaction to protect human interests.

B-284 Evaluating the Range of Serum Neurofiament Light Chain at Different Ages in Chinese

Abstract Background Neurofilament light chain (NFL) has recently been identified as a sensitive biomarker for diagnosis and prognosis in many neurological diseases. However, studies focused on NFL levels ranges in healthy individuals remain few, especially in the Chinese population. The clarification of the reference range among healthy individuals at different ages would be useful for further clinical utility. Objectives To evaluate the serum neurofilament light chain range at different ages in healthy Chinese and analyze the potential contributing factors for NFL levels. Methods Healthy individuals undergoing rigorous cognitive and neuroimaging detection were enrolled. Serum samples and plasma samples of different anticoagulants were collected for NFL levels detection by the ultra-sensitive Simoa HD-1 platform. The tendency of NFL levels to change with age and potential influence factors were analyzed. Results We enrolled three hundred and ninety-nine healthy participants. The positive correlation between serum NFL levels and age was observed and the regression formula was further established. There were no statistical differences between the <20 years group and the 20–29 years group (P = 0.2512), as well as the 60–69 years group and the 70–79 years group (P = 0.0528) and differences,were statistically significant among the remaining pairwise groups. We further observed the positive correlation between serum tNFL levels and age was 0.76 in total (P < 0.0001). The NFL levels between the serum and heparin plasma are statistically different and there was no statistical difference between the serum and plasma of other anticoagulants. Conclusions The age-related change pattern was uncovered, providing important assistance for the clinical use of NFL to monitor the potential neurological alterations for people of different ages.

GLOBAL TRENDS IN THE CREATION OF THEME ENTERTAINMENT SPOTS

Entertainment is one of the most important areas of people’s social practices, which significantly affects the state of society. Satisfaction with the quality and availability for the society is the development quotient of the country’s economy and its social sphere. In fact the formation of the entertainment industry is a direct consequence to reach a certain level of population income, when there is available cash. The practice of creating special conditions for the organization of entertainment processes led to the introduction of a potential entertainment industry, which has developed by the end of the 20th century. The article provides an overview of modern world trends in the design of theme recreational facilities based on the analysis of foreign and local experience. Their features and techniques used in creating a theme space are revealed. There are the examples of the most famous and iconic theme recreational facilities.
 The research purpose is to conduct the analysis of the existing theme recreational facilities and provide the recommendations for the designers. The presence of a theme leisure facility contributes to the development of the city and the region in general, they contain a whole infrastructure for receiving and serving the visitors. A theme recreational facility is a separate entertainment object created for the commercial purposes based on a popular theme (from literature, history, cinema, music, etc.), which is the tool for selecting and mythologizing space, is used in the elements of environmental design, complex symbolism, attractions etc. The analysis of the research work showed that the subject of the structure can be determined by the places associated with historical events, natural objects and conservation area, buildings and structures, memorial monuments, the works of architecture and urban planning, original engineering structures, objects, related to the life and activities of people, technical exhibits, art monuments, archaeological monuments, folk custom, modern or future achievements, etc. In order to unite people of different ages, the adult population are involved as the organizers of a short family trip, the main theme of the park is not only entertaining, but also informative.
 The scientific novelty of the research is in the fact that the regularity and possibility of applying this method allows to get a working tool that will help to design theme entertainment complexes.

Age-Related Dietary Habits and Blood Biochemical Parameters in Patients with and without Steatosis-MICOL Cohort.

Steatosis is now the most common liver disease in the world, present in approximately 25% of the global population. The aim of this study was to study the association between food intake and liver disease and evaluate the differences in blood parameters in age classes and steatosic condition. The present study included 1483 participants assessed in the fourth recall of the MICOL study. Patients were subdivided by age (</>65 years) and administered a validated food frequency questionnaire (FFQ) with 28 food groups. The prevalence of steatosis was 55.92% in the adult group and 55.88% in the elderly group. Overall, the results indicated many statistically significant blood parameters and dietary habits. Analysis of food choices with a machine learning algorithm revealed that in the adult group, olive oil, grains, processed meat, and sweets were associated with steatosis, while the elderly group preferred red meat, dairy, seafood, and fruiting vegetables. Furthermore, the latter ate less as compared with the adult group. Many differences were found between the two age groups, both in blood parameters and food intake. The random forest also revealed different foods predicted steatosis in the two groups. Future analysis will be useful to understand the molecular basis of these differences and how different food intake causes steatosis in people of different ages.

Quantitative Risk Assessment of Five Foodborne Viruses in Shellfish Based on Multiplex qPCR.

Foodborne diseases are currently the most critical food safety issue in the world. There are not many hazard identification and exposure assessments for foodborne viruses (Norovirus GI, GII, Hepatitis A Virus, Rotavirus, Adenovirus) in shellfish. Multiplex qPCR for the simultaneous detection of five foodborne viruses was established and used to assess infection risk based on a 1-year pathogenesis study. The sensitivity, specificity and reproducibility of the multiplex qPCR method are consistent with that of conventional qPCR, which saves more time and effort. Overall, 37.86% of shellfish samples had one or more foodborne viruses. Risk assessment formulae and matrices were used to develop risk assessments for different age groups, different seasons and different shellfish. The annual probability of contracting a foodborne virus infection from shellfish is greater than 1.6 × 10-1 for all populations, and even for infants aged 0-4 years, it is greater than 1.5 × 10-2, which is much higher than the risk thresholds recommended by WHO (10-6) and the US EPA (10-4). High risk (level IV) is associated with springtime, and medium risk (level III) is associated with Mussel consumption. This study provides a basis for the risk of foodborne viral infections in people of different ages, in different seasons, and by consuming different shellfish.

Analysis on Chi Forest's Market in China

With the rapid development of technology in the new era, social media has become an indispensable part of everyone's life, and the Internet has penetrated into the lives of people of different ages. At the same time, many products are promoted through the Internet. Of course, this also has certain disadvantages -- rapid popularity but short life cycle. However, this marketing method also saves many endangered brands, such as "Huaxizi air honey powder", "Ke Qi lip glaze", "Hongxing Erke". In 2020, the Chi Forest took "sugar free" as the name of the beverage brand to attract a lot of people's eyes and attention. It only took 4 years for Chi Forest to enter the market and occupy the market, so this paper used MLA model to study and analyze the marketing methods of this brand.The significance of this research is to analyze the marketing method of Chi Forest to determine whether this marketing model can be applied to the same type of products, or whether the unique marketing method can teach us anything from it.

The Popularity of K-Pop Culture in Russia: Good or Evil? The Case of BTS

The export and consumption of mass culture products through social networks is practically uncontrollable through globalization. The Republic of Korea, which has made a bet on its creative industries, has achieved noticeable success in this area. The number of fans of the Korean wave (Hallyu) is growing all over the world, in Russia too. K-pop, the musical component of Hallyu, is the most interesting because most of its fans are young people. This actualizes the question about consequences of the k-pop passion on the individual and societal levels. The purpose of the study: to analyze the causes and consequences of Russians’ passion for k-pop, in particular, the BTS creativity. The theoretical basis is the theory of the cultural industry by M. Horkheimer — T. Adorno and the theory of social media by M. McLuhan — G. Jenkins. The online fandom BTS — ARMY is seen as an informal social institution of mass culture. Empirical base. Online survey of Russian BTS fans (N=2483), 13 personal fan essays, 5 focus groups with people of different ages who are not fans but know them well. results. Results. The passion for k-pop, in particular BTS, is a form of response to the challenges of modern society, in particular, the growth of loneliness, competition, the devaluation of moral values and the crisis of family relations. Positive effects are associated with the personal development of fans, broadening their horizons, increasing self-confidence and tolerance, the emergence of new forms of leisure and hobbies. Participation in a fandom creates a sense of group identity and solidarity, and social networks allow the development of a “culture of participation”. Negative effects are manifested in the idealization of South Korea, its people and culture, the desire to remain in the “beautiful fairy tale” created by the South Korean cultural industries. As a result, groups of female fans are self-isolating. Considering an idol, far from Russian realities, as a normative model of a man, leads to difficulties in building partnerships between female fans with the opposite sex. Non-aggressive behavior of ARMY forms a generally tolerant attitude towards them. K-pop fandom is perceived as a childhood disease that will eventually go away without much treatment. According to opinion of focus group participants, it does not pose a threat to national security and the national identity of the inhabitants of Russia. directions for further research are related to a more detailed analysis of the mechanisms of BTS psychological support for their fans, a comparison of the socio-demographic composition and main types of activity of Russian fans of male and female K-pop groups, an assessment of the meaning of the “complicity culture”, which BTS fans create, for their personal development.

The characteristics of organized sport and physical activity initiatives for older adults in Sweden.

There is a common understanding that sport and physical activity can be important to address healthy aging. There are individual-level recommendations about how much physical activity people of different ages should engage in to gain health benefits, but at the same time there are no recommendations for how organizations should organize physical activities to suit as many people as possible for as long as possible. The purpose of this study was to explore the characteristics of sport and physical activity initiatives that older adults participate in. Different ongoing sport and physical activity initiatives that involve older adults were investigated regarding their focus, organization, intensity and organizer, and in relation to their costs, booking opportunities and recruitment. The study was conducted with a cross-sectional design using the Salutogenic Physical Activity Health Resources Questionnaire (SPAHRQ). The study included 27 different initiatives with 372 participants (60% women) ranging from 60 to 96 years of age. A health-promoting, salutogenic settings-based approach, and specifically the concepts drop-in, drop-through and drop-over were used in discussing recommendations for the organization of sport and physical activity for older adults. The main findings were that who organizes the sport and physical activity initiative seems to affect the characteristics of how it is organized and what characterizes the participants in it. Despite the differing characters of sport and physical activity initiatives, the majority of older adults are recruited by internal contacts like friends and family. Which older adults participate in which initiatives is explained mostly by the age and gender of the participants. In conclusion, to attract as many older adults as possible, organizations should work with lowering the thresholds, as well as within and between, organizations, and raise the threshold for dropping out of sports and physical activity.

Health risk assessment of nitrate pollution of drinking groundwater in rural areas of Suihua, China.

In order to investigate the health risks of NO3- in rural drinking groundwater in Suihua, China and provide a basis for healthy drinking water, 40 sets of groundwater samples were collected in the Suihua area, and the average concentration of nitrate in the study area was 71.66 mg/L, statistical analysis software (SPSS19), Hydrogeochemical Analysis Software (AqQA) and groundwater pollution analysis software were used. Through water sample collection, chemical analysis and construction of human health risk model (HHRA), a qualitative and quantitative assessment of NO3- health risk was carried out for people of different ages and sexes, and it was concluded that there was NO3- pollution health risk in rural drinking groundwater in Suihua. Health risk level: infants > children > adult females > adult males. The evaluation provides a scientific basis for the prevention and control of NO3- pollution in groundwater and new ideas for preventing human health risks.

Occurrence and exposure assessment of fumonisins from grains and grain products in Zhejiang Province in 2018-2019

To monitor fumonisins(FBs) in grains and grain products in Zhejiang and assess the exposure risks of FBs to local residents. Liquid chromatography coupled with tandem mass spectrometry method was used to determine the occurrence of FBs in rice, millet, dried noodles, instant noodles, and maize grains, and food frequency questionnaires were used to collect the food consumption data of Zhejiang population. Then, the simple probability distribution model was used to assess the exposure risk. The levels of FBs in rice, millet, dried noodles and instant noodles were relatively low. The occurrence of FB_1, FB_2 and FB_3 in these foods was 0-23.7%, 0-16.7% and 0-5.4%, respectively, and the mean levels were not detected(ND)-22.36, ND-20.63 and ND-7.19 μg/kg correspondingly. However, the levels of FBs in maize grains were relatively high. The occurrence of FB_1, FB_2, and FB_3 in maize grains was 100%, 93.6% and 90.3%, respectively, and the mean levels were 638.99, 103.54 and 59.69 μg/kg correspondingly. In 12.9% of the maize grain samples, the levels of FBs were higher than the standard reference. The residents were at low exposure risk overall. The mean estimated daily intake(EDI) of FBs was far lower than the provisional maximum tolerable daily intake of 2 μg/(kg·BW·d). However, 0.30% of the residents were at high risk. Among people of different ages, the mean EDI of children, adults, and elderly were 0.43, 0.28 and 0.29 μg/(kg·BW·d) respectively, and children were in the highest exposure levels of FBs. Among the tested five foodstuffs, rice and maize grains were the main sources of FBs exposure. Except for maize grains, the levels of FBs in grains and grain products were relatively low, and Zhejiang residents were at low FBs exposure risk generally.

An Analysis on Needs for National Parks by Age Group using Semantic Network Analysis

Background and objective: National parks are places people from all walks of life can utilize. However, many existing studies are limited in suggesting management plans that fit the characteristics of different age groups of people visiting national parks. Therefore, this study aims to identify the requirements for national parks and set the direction for national park services by age group.Methods: This study collected the requirements for national parks from 902 people of different ages through an online self-administered questionnaire and analyzed them through semantic link network analysis.Results: As a result of the analysis, there were management requirements in two areas related to the environment (rubbish and ecological environment, facilities environment such as safety and forest fires) and one area related to the economy, and a monitoring system for rubbish and ecological environment and a private land management policy for the economy were identified as alternatives. The younger generation was interested in environmental issues, the older generation was interested in economic issues, and the elderly was interested in the facilities environment for safety and forest fires. Therefore, it was found that environmental campaigns should be conducted for the younger generation, admission fees and parking rates should be improved for the older generation, and a safe tour environment should be provided for the elderly.Conclusion: The needs analysis found that it is necessary to establish a monitoring system for all national parks from an environmental perspective and improve the management policy about private land from an economic perspective. Furthermore, environmental campaigns and events were required for the younger generation, benefits related to entrance fees for the elderly, and policies to create a safe facilities environment for the elderly. Establishing such national park policies will improve the satisfaction of users.

Some reason prevalence of anxiety and depression among people of different ages: a review

some reason prevalence of anxiety and depression among people of different ages: a review

Evaluation of Caspase 8 Role as a Gene and Protein in Chronic Myeloid Leukemia Incidence

Chronic Myeloid Leukemia )CML( is a type of clonal hematopoietic stem cell disease marked by cytogenetic abnormalities induced by the growth and division of cells carrying the Philadelphia chromosome. The current research was carried out in Iraq to examine the link between Caspase 8 gene expression and Caspase 8 protein and the development of chronic myeloid leukemia (CML) in 100 samples (50 patients and 50 controls). There were differences in the expression of this gene between healthy controls and studied patients. The relationship between CML onset with age and gender was investigated in comparison to controls. The results revealed significant rises in the mean of Caspase 8 expression level (∆Ct) of patient groups in comparison to the related ∆Ct means in the healthy group, as well as significant differences in gene expression folding (2-∆∆Ct) of Caspase 8 gene, which reached (2.778) in CML patients, Caspase 8 protein levels were (0.1059 ng/ml) and There were considerable variations between CML patients and control groups. On the other hand, the results for gender and age of CML patients compared to controls indicated no significant differences for genders of CML patients and controls, and significant differences P &lt;0.0001 for age of CML patients and controls, this result suggests that CML may afflict people of different ages and affect both men and women.

Some reason prevalence of anxiety and depression among people of different ages: a review

some reason prevalence of anxiety and depression among people of different ages: a review